Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Triphala 500 mg Ingredients & Drug Interactions

by Pure Naturals Herbs

Triphala 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Triphala 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Triphala 500 mg is a dietary supplement by Pure Naturals Herbs with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, cholesterol and heart health, immune support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Amla, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Triphala 500 mg by Pure Naturals Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Triphala 500 mg by Pure Naturals Herbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Triphala 500 mg by Pure Naturals Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Triphala, Powder” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

Triphala 500 mg is a blend of three Ayurvedic fruits: haritaki, bibhitaki, and amla (Indian gooseberry). All three are powdered and combined in one capsule.

The only inactive ingredient listed is cellulose, a plant-based filler.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Indian Gooseberry's overall clinical evidence instead.

Moderate

Some clinical evidence supports Indian Gooseberry for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Dyslipidemia — rated "Possibly Effective" (Natural Medicines).
  • On file: Gastroesophageal reflux disease (GERD) — rated "Possibly Effective" (Natural Medicines).

Amla, one of the three Triphala components, is rated Possibly Effective for acid reflux (GERD) and high triglycerides (dyslipidemia) in our data. For high cholesterol and hair loss, the evidence is too thin to rate.

We hold no effectiveness data for haritaki or bibhitaki, so we can't say what Triphala as a whole does beyond what amla alone may offer.

The evidence, ingredient by ingredient Indian Gooseberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Triphala is generally well tolerated as food, but supplement safety at the doses used here is less studied. Pregnancy safety data aren't on file, so talk with your pharmacist or doctor if you're pregnant.

Breastfeeding safety is too unclear — avoid it unless you've checked with your healthcare provider first. In trials, a small number of people reported mild stomach upset or indigestion, and one or three reported fatigue or muscle pain — all uncommon.

Side effects, ingredient by ingredient Indian Gooseberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Indian Gooseberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Triphala, double-check these with your pharmacist: blood thinners and antiplatelet drugs (Moderate severity) — amla may raise bleeding risk; diabetes medications (Moderate severity) — amla may lower blood sugar too much; and aspirin or clopidogrel (Moderate severity) — similar bleeding concerns apply. No interactions are documented for the other two Triphala components in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Triphala may help with acid reflux or high triglycerides, but the evidence is modest. If you take blood thinners, diabetes drugs, or aspirin, or if you're pregnant or breastfeeding, check with your pharmacist before starting.

Use the drug checker below to see if any of your medications interact with this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Triphala 500 mg, straight from the product label.

Brand Pure Naturals Herbs
Barcode (UPC) 816511028170
Net contents 250 Veggie Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 323875
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Triphala 500 mg by Pure Naturals Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
250
UPC/BARCODE
816511028170
IngredientAmount% DV
Triphala, Powder500 mg--
Haritaki, Powder0 NP--
Bibhitaki, Powder0 NP--
Amla, Powder0 NP--

Other ingredients: Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, adults take one (1) veggie capsule daily, preferably after meals or as directed by a health care professional.

Precautions

Caution: Do not exceed recommended dose.

If you are pregnant, nursing, taking any medication(s) or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Visit us online @ purenaturals.co

Formula

Made with organic triphala

Formulation

Supports liver function Promotes digestive health Supports detoxification & regularity

Contains no: Preservative, artificial colors, flavors or sweeteners, sugar, starch, milk, lactose, soy, gluten, wheat, yeast, fish or sodium.

An FDA regulated facility

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in USA Sourced from a GMP Certified Facility Good Manufacturing Practice Quality Assured

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Triphala 500 mg by Pure Naturals Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Triphala 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Triphala 500 mg by Pure Naturals Herbs

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container250 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Triphala, Powder

500 mg per serving
  • › Haritaki, Powder
  • › Bibhitaki, Powder
  • › Amla, Powder

Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Triphala 500 mg by Pure Naturals Herbs Drug Interactions

Want to check YOUR meds against Triphala 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Amla, Powder 208

Individual Drug Interactions

The ingredients in Triphala 500 mg interact with 208 drugs. Click any drug to see the details.

1 of the 3 ingredients in Triphala 500 mg interact with drugs. Each result below shows which ingredient is responsible. Amla, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Triphala 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Amla, Powder4 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Aspirin

Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.

Likelihood Possible Evidence B
Clopidogrel (Plavix)

Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.

Likelihood Possible Evidence B
Amla, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Triphala 500 mg, from the product label.

Pure Naturals Herbs

See all Pure Naturals Herbs products
Name
Pure Naturals Herbs
City
Jersey City
State
NJ
Web Address
purenaturals.co
Pharmacist Counseling Corner

Triphala 500 mg by Pure Naturals Herbs: Common Questions

Does Triphala 500 mg by Pure Naturals Herbs interact with any medications?
Yes. Based on its ingredients, Triphala 500 mg has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Triphala 500 mg contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Triphala?
Triphala is an Ayurvedic blend of three fruit powders: haritaki, bibhitaki, and amla. Each ingredient has been used traditionally, though modern evidence for the combination is limited.
Can I take Triphala if I'm pregnant?
Pregnancy safety data aren't on file for these ingredients at supplement doses. Talk with your pharmacist or doctor before taking it.
Can I take Triphala if I'm breastfeeding?
Breastfeeding safety is too unclear in our data — it's best to avoid it unless you've checked with your healthcare provider.
Does Triphala help with digestion?
We have no effectiveness data on Triphala for digestion. Amla (one of the three components) is Possibly Effective for acid reflux, but evidence for the full blend is not established in our data.
What side effects have been reported?
In trials, a small number of people reported mild stomach upset or indigestion. One or three people reported fatigue or muscle pain. These are uncommon.
Can I take Triphala with my blood thinner?
No — not without checking with your pharmacist first. Amla in Triphala may increase bleeding risk if combined with blood thinners or aspirin. Your pharmacist can tell you if it's safe for your specific medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Triphala 500 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Triphala 500 mg label
Go deeper

The Full Monographs Behind Triphala 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Indian Gooseberry

Interacts with 208 drugs

Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion. Early research is promising for some u...

Read the full Indian Gooseberry monograph →
Sources

Sources & How We Checked

Triphala 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Indian Gooseberry 6 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21(5):579-85. PubMed
  3. Shanmugarajan D, Girish C, Harivenkatesh N, Chanaveerappa B, Prasanna Lakshmi NC. Antihypertensive and pleiotropic effects of Phyllanthus emblica extract as an add-on therapy in patients with essential hypertension-A randomized double-blind placebo-contro
  4. Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011;62(6):609-16.
  5. Usharani P, Fatima N, Muralidhar N. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 20 PubMed
  6. Majeed M, Mundkur L, Paulose S, Nagabhushanam K. Novel Emblica officinalis extract containing ß-glucogallin vs. metformin: a randomized, open-label, comparative efficacy study in newly diagnosed type 2 diabetes mellitus patients with dyslipidemia. Food Fu

See these in context on the Indian Gooseberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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