Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

U.T. Biotic Ingredients & Drug Interactions

by Vibrant Health

U.T. Biotic label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking U.T. Biotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

U.T. Biotic is a dietary supplement by Vibrant Health with 6 active ingredients. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.Based on those ingredients, 874 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are PACran whole Cranberry extract, L. helveticus, Probiotic Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against U.T. Biotic by Vibrant Health

Ask about any prescription or over-the-counter medication and we check it for interactions with U.T. Biotic by Vibrant Health — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of U.T. Biotic by Vibrant Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • “Probiotic Blend” is a proprietary blend — the label gives one combined amount (350 mg) without saying how much of each component you get.

U.T. Biotic contains 9 ingredients total: four identified probiotic strains (L. helveticus, L. acidophilus HA-122, and B. longum, plus a grouping called Probiotic Blend), four additional probiotic strains we list by name, fructo-oligosaccharides (a prebiotic fiber that feeds beneficial bacteria), and PACran whole cranberry extract.

The probiotics are live microorganisms intended to support your gut, while the fructo-oligosaccharides act as food for those bacteria. Cranberry extract is included for urinary tract support.

There are no inactive fillers listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports healthy urogenital flora and bladder function.
  • We looked for evidence on: Bacterial vaginosis, Antibiotic-associated diarrhea, Diarrhea, Lactose intolerance, Irritable bowel syndrome (IBS), Constipation — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Irritable bowel syndrome (IBS).
  • Also on file: Cranberry is rated "Possibly Effective" for Urinary tract infections (UTIs).

L. acidophilus shows possibly effective evidence for irritable bowel syndrome (IBS), antibiotic-associated diarrhea, bacterial vaginosis, and Helicobacter pylori infection. Cranberry extract is possibly effective for urinary tract infections (UTIs).

For the other probiotic strains in this product, the evidence for their listed uses is insufficient—we don't have enough data to rate them one way or the other. Fructo-oligosaccharides also lack sufficient evidence for the conditions listed.

The evidence, ingredient by ingredient Fructo-oligosaccharides (fos) Lactobacillus Helveticus Lactobacillus Acidophilus Bifidobacterium Longum Cranberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The probiotics are generally well tolerated in healthy adults. However, if you're seriously ill or have a weakened immune system, talk to your doctor first—there's a rare theoretical risk of infection from live organisms.

FOS (the prebiotic fiber) commonly causes mild gas, bloating, and abdominal discomfort, especially at higher doses, though clinical trials at moderate doses haven't consistently shown this. Cranberry is generally well tolerated, though concentrated supplement doses haven't been well studied—food amounts are considered likely safe.

For pregnancy and lactation, B. longum is rated possibly safe, but the other ingredients have insufficient data; talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Fructo-oligosaccharides (fos) Lactobacillus Helveticus Lactobacillus Acidophilus Bifidobacterium Longum Cranberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Lactobacillus Acidophilus, Cranberry, Bifidobacterium Longum, Lactobacillus Helveticus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 875 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking U.T. Biotic if you use antibiotic drugs (the probiotics may lose effectiveness if dosed together), blood thinners like warfarin, cholesterol-lowering statins like atorvastatin, or blood pressure medications like nifedipine.

The cranberry extract is the main source of these interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with IBS, antibiotic-associated diarrhea, bacterial vaginosis, or UTIs if you're looking for probiotic and cranberry support. If you take antibiotics, blood thinners, statins, or blood pressure medications, check your specific drugs with the tool on this page before starting.

Talk to your pharmacist or doctor if you're seriously ill, pregnant, breastfeeding, or have a weakened immune system.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 29, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about U.T. Biotic, straight from the product label.

Brand Vibrant Health
Barcode (UPC) 074306800343
Net contents 75 Gram(s); 2.65 oz.
Market status On market
Date entered into DSLD Dec 29, 2014
DSLD ID 40376
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for U.T. Biotic by Vibrant Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.5 Gram(s)
Maximum serving Sizes:
2.5 Gram(s)
Servings per container
30
UPC/BARCODE
074306800343
IngredientAmount% DV
Fructo-Oligosaccharides2000 mg--
L. helveticus2500000000 {Unit(s)}--
L. casei HA-1085000000000 {Unit(s)}--
L. acidophilus HA-1225000000000 {Unit(s)}--
L. rhamnosus HA-1115000000000 {Unit(s)}--
B. longum HA-1353750000000 {Unit(s)}--
Probiotic Blend350 mg--
L. brevis HA-1122500000000 {Unit(s)}--
L. fermentum HA-1791250000000 {Unit(s)}--
PACran whole Cranberry extract150 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

MADE IN THE USA SINCE 1992

*Formulated by Mark Timon, Founder, Vibrant Health MS Clinical Nutrition

{Recycle}

WHERE SCIENCE MEETS NATURE

Daily Maintenance Formula for Urogenital Health

+ 25 Billion Probiotics

Supports Healthy Urogenital Flora and Bladder Function for Men & Women*

CLINICALLY FORMULATED*

LOOK WHAT'S INSIDE

Good probiotic bacteria dominate the urinary and urogenital flora. Specific probiotics benefit healthy urogenital systems by inhibiting pathogenic bacteria. They resist attachment of undesirable bacteria, and/or produce hydrogen peroxide, lactic acid and other natural substances, which retard growth of potentially harmful bacteria.

Also Available in Vegetable Capsules, 30 count (UBC)

Formulation

GLUTEN FREE/SOY FREE

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

Directions As a dietary supplement, take one (1) scoop daily mixed into a cool beverage of your choice approximately one hour after eating.

Precautions

Keep out of reach of children.

Storage

Store in a cool dry place. REFRIGERATE AFTER OPENING

Brand IP Statement(s)

PACran(TM) provides a unique class of proanthocyanidins that is clinically shown to resist adhesion of unwelcome bacteria in the urinary tract.

Probiotics plus PACran(TM) may help maintain healthy urogenital microflora.*

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

U.T. Biotic by Vibrant Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

U.T. Biotic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in U.T. Biotic by Vibrant Health

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2.5 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fructo-Oligosaccharides

No known
interactions
2000 mg per serving

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...

Fructo-Oligosaccharides monograph & interactions

L. helveticus

Interacts with
182 drugs
2500000000 {Unit(s)} per serving

Lactobacillus helveticus is a lactic acid bacterium used as a probiotic, often combined with other strains in mood, gut, and general wellness products...

L. helveticus monograph & interactions

Probiotic Blend

Interacts with
182 drugs
350 mg per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic Blend monograph & interactions

L. brevis HA-112

2500000000 {Unit(s)} per serving

L. fermentum HA-179

1250000000 {Unit(s)} per serving

PACran whole Cranberry extract

Interacts with
712 drugs
150 mg per serving

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. I...

PACran whole Cranberry extract monograph & interactions
Interaction report

U.T. Biotic by Vibrant Health Drug Interactions

Want to check YOUR meds against U.T. Biotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
874Drugs
807 Moderate 67 Minor

Ingredients driving the most interactions

PACran whole Cranberry extract 712
L. helveticus 182
Probiotic Blend 182

Individual Drug Interactions

The ingredients in U.T. Biotic interact with 874 drugs. Click any drug to see the details.

3 of the 6 ingredients in U.T. Biotic interact with drugs. Each result below shows which ingredient is responsible. PACran whole Cranberry extract L. helveticus Probiotic Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in U.T. Biotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

PACran whole Cranberry extract6 drug types · 712 drugs

Atorvastatin (Lipitor)

Theoretically, cranberry might increase levels and adverse effects of atorvastatin.
In one case report, a patient taking atorvastatin experienced upper back pain, rhabdomyolysis, and abnormal liver function after drinking cranberry juice 16 ounces daily for 2 weeks. Theoretically, this may have been caused by inhibition of cytochrome P450 3A4 (CYP3A4) enzymes by cranberry juice, as atorvastatin is a CYP3A4 substrate. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Patients taking atorvastatin should avoid large quantities of cranberry juice.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
A case of upper back pain, rhabdomyolysis, and abnormal liver function has been reported for a patient taking atorvastatin, a CYP3A4 substrate, in combination with cranberry juice 16 ounces daily for 2 weeks. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Also, animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine, a CYP3A4 substrate, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Theoretically, cranberry might increase the levels and adverse effects of nifedipine.
Animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine treatment, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, cranberry might increase the levels and adverse effects of warfarin. However, research is conflicting.
There is contradictory evidence about the effect of cranberry juice on warfarin. Case reports have linked cranberry juice consumption to increases in the international normalized ratio (INR) in patients taking warfarin, resulting in severe spontaneous bleeding and excessive postoperative bleeding. Daily consumption of cranberry sauce for one week has also been linked to an increase in INR in one case report. In a small study in healthy young males, taking a high dose of 3 grams of cranberry juice concentrate capsules, equivalent to 57 grams of fruit daily, for 2 weeks produced a 30% increase in the area under the INR-time curve after a single 25-mg dose of warfarin. However, 3 very small clinical studies in patients stabilized on warfarin reported that cranberry juice 250 mL once or twice daily for 7 days (27% cranberry juice or pure cranberry juice) or 240 mL once daily for 14 days does not significantly increase INR or affect plasma warfarin levels. The reasons for these discrepant findings are unclear. It is possible that the form and dose of cranberry may play a role, as cranberry extracts and juices contain different constituents. Additionally, an in vitro study evaluating 5 different cranberry juices found varying effects, with only a cranberry concentrate, and not diluted cranberry juices, inhibiting CYP2C9. However, this concentrate did not inhibit CYP2C9 activity in humans.

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates. However, research is conflicting.
There is contradictory evidence about the effect of cranberry on CYP2C9 enzymes. In vitro evidence suggests that flavonoids in cranberry inhibit CYP2C9 enzymes. However, clinical research shows that cranberry juice does not significantly affect the levels, metabolism, or elimination of the CYP2C9 substrates flurbiprofen or diclofenac. Also, in patients stabilized on warfarin, drinking cranberry juice 250 mL daily for 7 days does not significantly increase the anticoagulant activity of warfarin, a CYP2C9 substrate. Additional pharmacokinetic research shows that cranberry juice does not increase peak plasma concentrations or area under the concentration-time curve of warfarin.

Likelihood Unlikely Evidence B
Diclofenac (Voltaren, Others)

Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
In vitro evidence suggests that cranberry juice inhibits diclofenac metabolism by human liver microsomes. However, drinking cranberry juice does not seem to affect diclofenac metabolism in humans.

Likelihood Unlikely Evidence B
PACran whole Cranberry extract full monograph & interactions

L. helveticus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L. helveticus.
Lactobacillus helveticus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. helveticus preparations by at least two hours.

Likelihood Probable Evidence D
L. helveticus full monograph & interactions

Probiotic Blend1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for U.T. Biotic, from the product label.

Vibrant Health

See all Vibrant Health products
Name
Vibrant Health
City
Canaan
State
CT
ZipCode
06018
Phone Number
1-800-242-1835
Web Address
vibranthealth.us
Pharmacist Counseling Corner

U.T. Biotic by Vibrant Health: Common Questions

Does U.T. Biotic by Vibrant Health interact with any medications?
Yes. Based on its ingredients, U.T. Biotic has a known interaction with 874 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
U.T. Biotic contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with my antibiotic?
The probiotics in U.T. Biotic may lose their effectiveness if you take them at the same time as an antibiotic, since antibiotics can kill the live bacteria. Try spacing doses at least a few hours apart, and ask your pharmacist for specific timing advice for your medication.
Does this product actually work for UTIs?
The cranberry extract in U.T. Biotic is possibly effective for urinary tract infections. L. acidophilus also has possibly effective evidence for certain conditions, but the evidence for most of the other probiotic strains in this product is insufficient to rate.
Will this cause gas and bloating?
Yes, it's common. The fructo-oligosaccharides (prebiotic fiber) can cause abdominal pain, bloating, and flatulence, especially at higher doses. Clinical trials at moderate doses haven't consistently shown this, so your experience may vary. Starting with a smaller amount may help.
Is this safe during pregnancy?
One ingredient, B. longum, is rated possibly safe in pregnancy. The others don't have enough safety data on file. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy—it's an individual decision based on your health.
Is this safe if I take blood thinners like warfarin?
The cranberry extract in this product may increase warfarin's effects and raise your bleeding risk. You should definitely check with your pharmacist before taking U.T. Biotic if you're on warfarin or any other blood thinner.
What are the inactive ingredients?
There are no inactive fillers listed for this product—it contains only the active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if U.T. Biotic is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

U.T. Biotic label
Go deeper

The Full Monographs Behind U.T. Biotic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fructo-oligosaccharides (fos)

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...

Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monograph

Lactobacillus Helveticus

Interacts with 182 drugs

Lactobacillus helveticus is a lactic acid bacterium used as a probiotic, often combined with other strains in mood, gut, and general wellness products. Early research is interesting—especial...

Read the full Lactobacillus Helveticus monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Cranberry

Interacts with 712 drugs

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. It is not a reliable treatment for an act...

Read the full Cranberry monograph →
Sources

Sources & How We Checked

U.T. Biotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 77 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fructo-oligosaccharides (fos) 6 references
  1. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
  6. Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed

See these in context on the Fructo-oligosaccharides (fos) monograph →

Lactobacillus Helveticus 2 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

See these in context on the Lactobacillus Helveticus monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
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See these in context on the Bifidobacterium Longum monograph →

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See these in context on the Cranberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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