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Dietary supplement

Umckaloabo Ingredients & Drug Interactions

by Herb Pharm

Umckaloabo label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Umckaloabo against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Umckaloabo is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for acute bronchitis, common cold, sinusitis.Based on those ingredients, 241 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Umckaloabo Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Umckaloabo by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Umckaloabo by Herb Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Umckaloabo by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Umckaloabo Root Extract, which comes from Pelargonium sidoides, a traditional South African plant. The liquid also includes cane alcohol, distilled water, and glycerin as inactive ingredients to preserve and deliver the extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Respiratory system support.
  • We looked for evidence on: Acute Bronchitis, Rhinosinusitis, Tonsillopharyngitis, Upper respiratory tract infection (URTI), Common cold, Sore throat.
  • The strongest evidence on file: Umckaloabo is rated "Possibly Effective" for Acute Bronchitis (Natural Medicines).
  • Also on file: Umckaloabo is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Rhinosinusitis, Tonsillopharyngitis.

The evidence for Umckaloabo is modest. It's rated possibly effective for acute bronchitis (short-term bronchitis) and for chronic obstructive pulmonary disease (COPD), meaning there's some supporting research but it's not conclusive.

For sore throat and tonsillopharyngitis, there's insufficient reliable evidence to know whether it works.

The evidence, ingredient by ingredient Umckaloabo

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Umckaloabo is generally well tolerated for short-term use, though quality and standardization can vary between products. The most common side effects are allergic skin rash, diarrhea, and mild stomach upset.

It does not appear to damage your liver. During pregnancy, safety has not been established, so it's best avoided.

There isn't enough safety information for breastfeeding either — talk with your pharmacist or doctor before using it if you're nursing.

Side effects, ingredient by ingredient Umckaloabo

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Umckaloabo.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 241 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting if you take immunosuppressants (Moderate interaction) or blood thinners like warfarin, aspirin, or clopidogrel (Minor interaction). Use the medication search tool on this page with your exact drug names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Umckaloabo may help with acute bronchitis or COPD symptoms based on possibly effective evidence. If you take immunosuppressants or blood thinners, check with your pharmacist first — the interaction risk is real.

For short-term use in otherwise healthy people, it's generally well tolerated, but quality varies by brand.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Umckaloabo, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700004446
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 307754
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Umckaloabo by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
0.7 mL
Servings per container
42
UPC/BARCODE
090700004446
IngredientAmount% DV
Umckaloabo Root Extract657 mg--

Other ingredients: Cane Alcohol, Water, Distilled, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Shake well before using Adults: Add 1 squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.

Precautions

Keep out of the reach of children

Storage

Store away from heat & light

Formula

Pelargonium sidoides

Umckaloabo liquid extract

Formulation

Respiratory system

Gluten-free

Certified organic by Organic Certifiers

Seals/Symbols

USDA Organic

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Umckaloabo by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Umckaloabo label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Umckaloabo by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container42 Amounts shown are per serving.

Umckaloabo Root Extract

Interacts with
241 drugs
657 mg per serving

Umckaloabo is a root extract from a South African geranium that is most studied for short-term relief of acute bronchitis and other respiratory infect...

Umckaloabo Root Extract monograph & interactions

Other (inactive) ingredients: Cane Alcohol, Water, Distilled, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Umckaloabo by Herb Pharm Drug Interactions

Want to check YOUR meds against Umckaloabo?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
241Drugs
121 Moderate 120 Minor

Ingredients driving the most interactions

Umckaloabo Root Extract 241

Individual Drug Interactions

The ingredients in Umckaloabo interact with 241 drugs. Click any drug to see the details.

1 of the 1 ingredient in Umckaloabo interact with drugs. Each result below shows which ingredient is responsible. Umckaloabo Root Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Umckaloabo with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Umckaloabo Root Extract2 drug types · 241 drugs

Immunosuppressants

Theoretically, Pelargonium sidoides might decrease the effectiveness of immunosuppressant therapy.
In vitro research suggests that Pelargonium sidoides has immunostimulant effects.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, Pelargonium sidoides might increase the risk of bleeding when taken with anticoagulant and antiplatelet drugs.
Pelargonium sidoides contains coumarin, which may reduce platelet aggregation. However, in animal models, Pelargonium sidoides extract does not appear to inhibit coagulation or interact with warfarin. This interaction has not been documented in humans.

Likelihood Unlikely Evidence D
Umckaloabo Root Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Umckaloabo, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Umckaloabo by Herb Pharm: Common Questions

Does Umckaloabo by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Umckaloabo has a known interaction with 241 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Umckaloabo contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Umckaloabo if I'm pregnant?
No, safety has not been established during pregnancy, so the safety data advises against it. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy.
Can I take this while breastfeeding?
There isn't enough safety information to know either way. It's best to avoid it while nursing, but discuss your situation with your pharmacist or doctor for personalized advice.
What's the most common side effect?
Allergic skin rash, diarrhea, and gastrointestinal upset are the most common side effects reported. Most people tolerate it well for short-term use.
Does Umckaloabo actually work for bronchitis?
It's rated possibly effective for acute bronchitis — meaning there's some research supporting it, but the evidence isn't definitive. Results vary by individual.
What is Pelargonium sidoides?
It's a plant from South Africa traditionally used for respiratory symptoms. Umckaloabo is an extract made from its root.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Umckaloabo is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Umckaloabo label
Go deeper

The Full Monographs Behind Umckaloabo’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Umckaloabo

Interacts with 241 drugs

Umckaloabo is a root extract from a South African geranium that is most studied for short-term relief of acute bronchitis and other respiratory infections. Some clinical research suggests it...

Read the full Umckaloabo monograph →
Sources

Sources & How We Checked

Umckaloabo's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Umckaloabo 16 references
  1. Chuchalin AG, Berman B, Lehmacher W. Treatment of acute bronchitis in adults with a pelargonium sidoides preparation (EPs 7630): A randomized, double-blind, placebo-controlled trial. Explore 2005;1:437-45. PubMed
  2. Kolodziej H, Kayser O, Radtke OA, et al. Pharmacological profile of extracts of Pelargonium sidoides and their constituents. Phytomedicine 2003;10 Suppl 4:18-24. PubMed
  3. Bereznoy VV, Riley DS, Wassmer G, Heger M. Efficacy of extract of Pelargonium sidoides in children with acute non-group A beta-hemolytic streptococcus tonsillopharyngitis: a randomized, double-blind, placebo-controlled trial. Altern Ther Health Med 2003;9
  4. Kolodziej H, Kiderlen AF. In vitro evaluation of antibacterial and immunomodulatory activities of Pelargonium reniforme, Pelargonium sidoides and the related herbal drug preparation EPs 7630. Phytomedicine 2007;14 Suppl 6:18-26. PubMed
  5. Koch E, Biber A. Treatment of rats with the Pelargonium sidoides extract EPs 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin. Phytomedicine 2007;14 Suppl 6:40-5. PubMed
  6. Conrad A, Hansmann C, Engels I, et al. Extract of Pelargonium sidoides (EPs 7630) improves phagocytosis, oxidative burst, and intracellular killing of human peripheral blood phagocytes in vitro. Phytomedicine 2007;14 Suppl 6:46-51. PubMed
  7. Matthys H, Kamin W, Funk P, Heger M. Pelargonium sidoides preparation (EPs 7630) in the treatment of acute bronchitis in adults and children. Phytomedicine 2007;14 Suppl 6:69-73. PubMed
  8. Conrad A, Jung I, Tioua D, et al. Extract of Pelargonium sidoides (EPs 7630) inhibits the interactions of group A-streptococci and host epithelia in vitro. Phytomedicine 2007;14 Suppl 6:52-9. PubMed
  9. Matthys, H., Eisebitt, R., Seith, B., and Heger, M. Efficacy and safety of an extract of Pelargonium sidoides (EPs 7630) in adults with acute bronchitis. A randomised, double-blind, placebo-controlled trial. Phytomedicine 2003;10 Suppl 4:7-17. PubMed
  10. de Boer, H. J., Hagemann, U., Bate, J., and Meyboom, R. H. Allergic reactions to medicines derived from Pelargonium species. Drug Saf 2007;30(8):677-680. PubMed
  11. Teschke R, Frenzel C, Schulze J, Eickhoff A. Spontaneous reports of primarily suspected herbal hepatotoxicity by Pelargonium sidoides: was causality adequately ascertained? Regul Toxicol Pharmacol 2012;63(1):1-9. PubMed
  12. Teschke R, Frenzel C, Wolff A, et al. Initially purported hepatotoxicity by Pelargonium sidoides: the dilemma of pharmacovigilance and proposals for improvement. Ann Hepatol 2012;11(4):500-12. DOI
  13. Riley DS, Lizogub VG, Zimmermann A, Funk P, Lehmacher W. Efficacy and tolerability of high-dose Pelargonium extract in patients with the common cold. Altern Ther Health Med 2018;24(2):16-26.
  14. Matthys H, Pliskevich DA, Bondarchuk OM, Malek FA, Tribanek M, Kieser M. Randomised, double-blind, placebo-controlled trial of EPs 7630 in adults with COPD. Respir Med 2013;107(5):691-701. PubMed
  15. Willcox M, Simpson C, Wilding S, et al. Pelargonium sidoides root extract for the treatment of acute cough due to lower respiratory tract infection in adults: a feasibility double-blind, placebo-controlled randomised trial. BMC Complement Med Ther 2021;21 PubMed
  16. Kamin W, Behre U, Helm K, Reling B, Funk P, Malek FA. Safety of Pelargonium extract EPs 7630 in young children with acute bronchitis. Front Pediatr 2023;11:1107984. PubMed

See these in context on the Umckaloabo monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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