No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 9 ingredients. Check your meds →
Dietary supplement

V-Nzyme Blend Ingredients & Drug Interactions

by Klaire Labs

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

V-Nzyme Blend is a dietary supplement by Klaire Labs with 9 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of V-Nzyme Blend by Klaire Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.
  • “Enzyme Blend” is a proprietary blend — the label gives one combined amount (700 mg) without saying how much of each component you get.

V-Nzyme Blend contains 9 active ingredients, all digestive enzymes designed to help break down food. Protease and acid protease break down proteins; lipase tackles fats; amylase and cellulase work on carbohydrates and fiber.

Alpha-galactosidase helps with complex sugars that can cause gas. The blend also includes three fungal enzyme sources: aspergillus niger, aspergillus oryzae, and rhizopus oryzae.

Several inactive ingredients like slippery elm and marshmallow are also present in the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Enzyme supplement for digestive support.
  • We looked for evidence on: Dyspepsia, Indigestion, Bloating, Pancreatic insufficiency.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for these enzymes is limited. Lipase has been studied for inflammatory bowel disease (IBD) and dyspepsia (indigestion), but the data we hold rates both as having insufficient reliable evidence.

We don't have effectiveness ratings on file for protease, acid protease, or the other active ingredients in this blend.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and acid protease are generally well tolerated in most adults, though some people report digestive upset or allergic reactions. Rarely, occupational exposure to these enzymes has caused allergic rhinoconjunctivitis or asthma — mainly in industrial settings.

Lipase is similarly well tolerated in supplement form, but people with serious digestive conditions should use it only under medical guidance. During pregnancy, the safety data for protease and acid protease advises against use unless prescribed by your doctor; for lipase, use only if your doctor recommends it.

Breastfeeding is not recommended for any of these without medical advice due to limited safety data.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. If you take prescription medications, use the interaction search tool on this page or ask your pharmacist to be sure.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

V-Nzyme Blend is a multi-enzyme product for digestive support with no documented medication interactions for the ingredients we checked. It's generally well tolerated in adults, but people with serious digestive conditions, pregnant people, or those breastfeeding should check with their doctor or pharmacist first before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about V-Nzyme Blend, straight from the product label.

Brand Klaire Labs
Barcode (UPC) 828054005501
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 265037
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for V-Nzyme Blend by Klaire Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
828054005501
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Cellulase0 NP--
Alpha-Galactosidase0 NP--
Acid Protease0 NP--
Enzyme Blend700 mg--
Aspergillus niger0 NP--
Aspergillus oryzae0 NP--
Rhizopus oryzae0 NP--

Other ingredients: Hydroxypropylmethylcellulose, Water, Microcrystalline Cellulose, Slippery Elm, Marshmallow, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Enzyme Supplement

Brand IP Statement(s)

SFI

Precautions

Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product.

Keep out of reach of children.

Do not use if shrinkwrap is broken or missing.

Formulation

Free of the following common allergens: Milk/casein, eggs, fish, shellfish, tree nuts, and peanuts. Contains no artificial colors, flavors, or preservatives.

Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule with each meal or as directed by a healthcare professional.

General Statements

Enzyme units as defined by the Food Chemicals Codex (FCC).

Storage

Store in a cool, dry place (59 degrees F - 85 degrees F) away from direct light.

See for yourself

V-Nzyme Blend by Klaire Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in V-Nzyme Blend by Klaire Labs

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Enzyme Blend

700 mg per serving
  • › Amylase
  • Protease
  • Lipase
  • › Cellulase
  • › Alpha-Galactosidase
  • Acid Protease
  • › Aspergillus niger
  • › Aspergillus oryzae
  • › Rhizopus oryzae

Other (inactive) ingredients: Hydroxypropylmethylcellulose, Water, Microcrystalline Cellulose, Slippery Elm, Marshmallow, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

V-Nzyme Blend by Klaire Labs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in V-Nzyme Blend. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for V-Nzyme Blend, from the product label.

Klaire Labs

See all Klaire Labs products
Name
SFI USA
City
Reno
State
NV
ZipCode
89521
Web Address
Klaire.com
Pharmacist Counseling Corner

V-Nzyme Blend by Klaire Labs: Common Questions

Does V-Nzyme Blend by Klaire Labs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in V-Nzyme Blend. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
V-Nzyme Blend contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
The safety data for protease and acid protease advises against use during pregnancy unless your doctor prescribes it. For lipase, use only if your doctor recommends it. There isn't enough data on the other ingredients. Talk with your doctor or pharmacist about your situation before starting.
Is it safe to use while breastfeeding?
There's not enough safety data on any of the main ingredients during breastfeeding. Use is not recommended without medical advice. Check with your healthcare provider first.
What are the side effects?
Protease and acid protease may cause digestive upset or allergic reactions in some people. Rarely, these enzymes have triggered allergic rhinoconjunctivitis or asthma with occupational exposure. Lipase has no adverse effects reported in adults, though a complete safety evaluation hasn't been done. Most people tolerate these enzymes well.
Who shouldn't take this product?
People with serious digestive conditions should use this only under medical guidance. Those with a history of allergic reactions to enzymes or enzyme-containing products should be cautious. Pregnant people and those breastfeeding should talk with their doctor first.
Does this actually work for digestion?
The evidence is limited. For lipase, studies on indigestion and inflammatory bowel disease didn't show enough reliable evidence to rate its effectiveness. We don't have effectiveness data on file for the other enzymes in this blend.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if V-Nzyme Blend is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

V-Nzyme Blend label
Sources

Sources & How We Checked

V-Nzyme Blend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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