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Dietary supplement

D-Chiro-Inositol Ingredients & Drug Interactions

by Klaire Labs

D-Chiro-Inositol label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Chiro-Inositol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

D-Chiro-Inositol is a dietary supplement by Klaire Labs with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are D-Chiro Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against D-Chiro-Inositol by Klaire Labs

Ask about any prescription or over-the-counter medication and we check it for interactions with D-Chiro-Inositol by Klaire Labs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of D-Chiro-Inositol by Klaire Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-Chiro Inositol. Inositol is a naturally occurring compound your body makes and gets from food; it plays a role in cell signaling and may support insulin sensitivity and ovary function.

The capsule also holds inactive ingredients including hydroxypropyl methylcellulose, water, silicified microcrystalline cellulose, and calcium carbonate, which are fillers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Inositol support for metabolic and reproductive health.
  • We looked for evidence on: Polycystic ovary syndrome (PCOS), Anxiety, Depression, Panic disorder, Metabolic syndrome, Diabetes — and 4 related terms.
  • The strongest evidence on file: Inositol is rated "Possibly Effective" for Polycystic ovary syndrome (PCOS) (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Effective" for Metabolic syndrome.
  • Also on file: Inositol is rated "Possibly Ineffective" for Anxiety, Depression.

The evidence shows D-Chiro Inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome. It's also possibly effective for preventing preterm labor.

For anxiety, diabetic nerve pain (diabetic neuropathy), and depression, the evidence rates it possibly ineffective, meaning the data doesn't support benefit for those uses.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated at typical doses. The most common side effects are digestive: diarrhea, gas, and nausea.

In clinical research, inositol combined with omega-3 fatty acids was associated with cold and allergy symptoms in children, though this was a specific combination. If you're pregnant or breastfeeding, there isn't enough reliable safety data to say it's appropriate, even though it's sometimes studied in pregnancy.

Talk with your doctor or pharmacist before using it if you're pregnant, planning pregnancy, or nursing.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any antidiabetes medications—insulin, metformin, glipizide, and similar drugs—before taking this product. Inositol lowers blood glucose, and combining it with diabetes medication increases your risk of low blood sugar (hypoglycemia).

Use the search tool below to verify your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

D-Chiro Inositol may help with PCOS, metabolic syndrome, and preterm labor prevention, but it's mainly a consideration if you're managing one of those conditions. If you take any diabetes medication, this product requires a careful check—low blood sugar is a real risk.

Talk to your pharmacist before starting, especially if you're on insulin or oral diabetes drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Chiro-Inositol, straight from the product label.

Brand Klaire Labs
Barcode (UPC) 828054001633
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 322268
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Chiro-Inositol by Klaire Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
828054001633
IngredientAmount% DV
D-Chiro Inositol150 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Water, Silicified Microcrystaline Cellulose, Calcium Carbonate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Free of the following common allergens: milk/casein, eggs, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, corn, and yeast. Contains no artificial colors, flavors, or preservatives.

Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.

Suggested/Recommended/Usage/Directions

Suggested use: 1 capsule twice daily with food or as directed by a healthcare professional.

Brand IP Statement(s)

Chirositol is a registered trademark of Cyvex Nutrition, Inc.

Formula

D-Chiro-Inositol is a naturally-occurring inositol isomer extracted from the juice of carob pods.

Precautions

Do no use if shrinkwrap is broken or missing.

Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product.

Keep out of reach of children.

Storage

Store in a cool, dry place (59 degrees F-85 degrees F) away from direct light.

FDA Statement of Identity

Dietary Supplement

General Statements

SFI

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Chiro-Inositol by Klaire Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Chiro-Inositol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Chiro-Inositol by Klaire Labs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

D-Chiro Inositol

Interacts with
86 drugs
150 mg per serving Form: Chirositol

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

D-Chiro Inositol monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Water, Silicified Microcrystaline Cellulose, Calcium Carbonate. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Chiro-Inositol by Klaire Labs Drug Interactions

Want to check YOUR meds against D-Chiro-Inositol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

D-Chiro Inositol 86

Individual Drug Interactions

The ingredients in D-Chiro-Inositol interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in D-Chiro-Inositol interact with drugs. Each result below shows which ingredient is responsible. D-Chiro Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in D-Chiro-Inositol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

D-Chiro Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
D-Chiro Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for D-Chiro-Inositol, from the product label.

Klaire Labs

See all Klaire Labs products
Name
SFI USA
City
Reno
State
NV
ZipCode
89521
Web Address
Klaire.com
Pharmacist Counseling Corner

D-Chiro-Inositol by Klaire Labs: Common Questions

Does D-Chiro-Inositol by Klaire Labs interact with any medications?
Yes. Based on its ingredients, D-Chiro-Inositol has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
D-Chiro-Inositol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does D-Chiro Inositol really work for PCOS?
The evidence says it's possibly effective for PCOS. That means there's some support for benefit, but it's not proven beyond doubt. If you have PCOS, it's worth discussing with your doctor whether it makes sense to try alongside your other treatments.
What are the side effects?
The most common are digestive: diarrhea, gas, and nausea. These tend to be mild. In one study pairing inositol with omega-3s, children reported cold and allergy-like symptoms, though that's a specific combination, not this product alone.
Is it safe if I'm pregnant?
There isn't enough reliable safety data to say for certain. Although researchers have studied it in pregnancy, full safety isn't established. If you're pregnant or planning pregnancy, talk with your doctor or pharmacist before taking it—they can weigh your individual situation.
Can I take this with my diabetes medicine?
You need to check with your pharmacist first. Inositol lowers blood sugar, so adding it to diabetes medication can increase the risk of low blood sugar (hypoglycemia). Use the medication checker below to see if your specific drugs are affected.
Does it help with anxiety or depression?
According to the evidence we have, D-Chiro Inositol is rated possibly ineffective for both anxiety and depression, so it's not a proven option for those uses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Chiro-Inositol is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Chiro-Inositol label
Go deeper

The Full Monographs Behind D-Chiro-Inositol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

D-Chiro-Inositol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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