Vita-Mind Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Vita-Mind against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Vita-Mind is a dietary supplement by Market America with 3 active ingredients. Its ingredients are commonly taken for preventing or treating magnesium deficiency, constipation, muscle cramps.Based on those ingredients, 746 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Saffron Stigma Extract, Gamma-Aminobutyric Acid, Magnesium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Vita-Mind by Market America
Ask about any prescription or over-the-counter medication and we check it for interactions with Vita-Mind by Market America — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Vita-Mind by Market America
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Vita-Mind contains three active ingredients. Magnesium plays roles in muscle and nerve function, bone health, and energy production — in this product it's included for its established effectiveness in relieving indigestion, constipation, and low magnesium levels, and for use in pregnancy-related high blood pressure.
Gamma-aminobutyric Acid (GABA) is a brain chemical that promotes relaxation, though the evidence for its effectiveness in anxiety, ADHD, and other conditions hasn't been established in our data. Saffron Stigma Extract is included for its possibly effective use in chemotherapy-related nerve pain and Alzheimer's disease.
The capsule also contains inactive ingredients: hydroxypropyl methylcellulose, cellulose, magnesium stearate, and silicon dioxide.
Does it work?
Not established
Magnesium in this product is established as effective for indigestion, constipation, low magnesium levels, and pre-eclampsia (high blood pressure in pregnancy). GABA's effectiveness for anxiety, ADHD, chronic bronchitis, cerebral palsy, and athletic performance hasn't been established in the data we hold — the evidence is insufficient to rate it.
Saffron stigma extract is possibly effective for chemotherapy-related nerve pain and Alzheimer's disease, based on available research.
How safe is it?
Well-documented data
Magnesium is generally well tolerated at recommended doses and is needed in pregnancy, but supplements should only be used under a doctor's guidance during pregnancy. Taken orally, the most common side effects are diarrhea, nausea, vomiting, and gastrointestinal irritation.
In rare cases, very high doses may cause a bezoar (a blockage in the stomach). GABA seems well tolerated short-term, but long-term safety hasn't been well studied; you should avoid it while breastfeeding due to insufficient safety information.
Common GABA side effects include drowsiness, nausea, muscle weakness, and mild throat irritation. Saffron is likely safe at food amounts but should be used carefully at supplement doses.
The most common side effects are gastrointestinal upset, nausea, vomiting, and sedation. Saffron should be avoided during pregnancy as it may stimulate the uterus.
Rare serious reactions include anaphylaxis (severe allergic reaction). Long-term breastfeeding safety isn't well established, so it's best to avoid supplement amounts.
Meds to double-check
Major interaction found
If you take Levodopa/Carbidopa for Parkinson's disease, do not use this product without talking to your pharmacist — magnesium can significantly reduce how well it works. Also check with your pharmacist if you take skeletal muscle relaxants, blood pressure medications (especially calcium channel blockers or potassium-sparing diuretics), diabetes drugs, quinolone antibiotics, or bisphosphonates for bone health.
Additionally, let your pharmacist know if you take any sedating medications (sleep aids, anti-anxiety drugs) or if you regularly drink caffeinated beverages, since saffron in this product may interact.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
Vita-Mind might interest someone looking to address constipation or indigestion, or whose doctor has recommended magnesium for pregnancy-related high blood pressure. If you take any medication for Parkinson's disease, blood pressure, diabetes, muscle relaxation, or antibiotics, talk to your pharmacist before starting — the interactions here can change how well those drugs work.
Pregnant or breastfeeding people should discuss this product with their doctor or pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Vita-Mind, straight from the product label.
| Brand | Market America |
|---|---|
| Barcode (UPC) | 848570019790 |
| Net contents | 60 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 313427 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Vita-Mind by Market America, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Magnesium | 110 mg | 26% |
| Gamma-Aminobutyric Acid | 29 mg | -- |
| Saffron Stigma Extract | 30 mg | -- |
Other ingredients: Hydroxypropyl Methylcellulose, Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Mental emotional balance
Manufactured in an FDA Registered Facility using Good Manufacturing Practices (GMPs).
Gluten free
Vegan
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions for use: As a dietary supplement, for ages 12 and older, take 2 capsules daily on an empty stomach or as directed by your healthcare provider.
Precautions
Warning: Do not use if you have bipolar disorder. If you are currently being treated for severe anxiety or depression, consult your healthcare provider before using this product.
If you are currently using any prescription drugs, have any other ongoing medical condition or if you are pregnant or breastfeeding, consult your healthcare provider before using this product.
Keep out of the reach of children.
Do not use if safety seal is broken or missing.
Resale on third-party websites is strictly prohibited unless specifically authorized by Market America or its corporate affiliates. If barcodes are altered or you purchase this product from an unauthorized third-party website, the product is not guaranteed by Market America or its corporate affiliates.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Vegan
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Vita-Mind by Market America label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Vita-Mind by Market America
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Magnesium
Interacts with295 drugs
Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preven...
Magnesium monograph & interactionsGamma-Aminobutyric Acid
Interacts with419 drugs
GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...
Gamma-Aminobutyric Acid monograph & interactionsSaffron Stigma Extract
Interacts with521 drugs
Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research us...
Saffron Stigma Extract monograph & interactionsOther (inactive) ingredients: Hydroxypropyl Methylcellulose, Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Vita-Mind by Market America Drug Interactions
HelloPharmacist Interaction Report
Vita-Mind by Market America does interact with a number of medications, primarily through its magnesium content.
Magnesium has a Major interaction with Levodopa/Carbidopa (Sinemet), a Parkinson's medication — magnesium can reduce how much of this drug your body absorbs, cutting levodopa levels by about 35% and carbidopa by 81%. This could make the medication less effective at controlling symptoms.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions affect several other drug types. Magnesium can increase the effects and speed up the action of skeletal muscle relaxants, potentially causing too much muscle relaxation.
Potassium-sparing diuretics (water pills that spare potassium) may cause magnesium to build up in your system. Calcium channel blockers (heart and blood pressure drugs) may have additive blood pressure-lowering effects with magnesium.
Magnesium also increases how much your body absorbs sulfonylureas (diabetes drugs), raising the risk of low blood sugar (hypoglycemia). It can reduce absorption of quinolone antibiotics and bisphosphonates (bone drugs), and acid-reducing medications may reduce magnesium's laxative effect.
GABA and saffron stigma extract each add their own interactions. GABA may lower blood pressure with antihypertensive drugs and could have additive sedative effects with CNS depressants (sleep aids, anti-anxiety medications).
Saffron may enhance the blood pressure-lowering effect of antihypertensive drugs, increase the risk of low blood sugar with diabetes medications, cause drowsiness when combined with sedating drugs, and theoretically slow how your body breaks down caffeine.
Altogether, these interactions span 741 individual medications. Use the medication checker on this page with your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Vita-Mind?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Vita-Mind interact with 746 drugs. Click any drug to see the details.
3 of the 3 ingredients in Vita-Mind interact with drugs. Each result below shows which ingredient is responsible. Saffron Stigma Extract Gamma-Aminobutyric Acid Magnesium
Benserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Benserazide, Levodopa interactionCarbidopaLodosyn
How Carbidopa interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Carbidopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Carbidopa, Levodopa, Entacapone interactionLevodopaInbrija, Larodopa
How Levodopa interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Levodopa, Carbidopa interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
Saffron Stigma ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Saffron Stigma Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Read the full Saffron Stigma Extract + Acebutolol interactionGamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Acebutolol interactionAcepromazineAtravet
How Acepromazine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acepromazine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acepromazine interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Stigma Extract + Acetaminophen, Aspirin, Caffeine interactionMagnesiumAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
Read the full Magnesium + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
Saffron Stigma ExtractCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Stigma Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCaffeine, Cns Depressants Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Stigma Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Butalbital, Codeine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCaffeine, Cns Depressants Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Stigma Extract + Acetaminophen, Caffeine, Codeine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCaffeine, Cns Depressants Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Stigma Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
Saffron Stigma ExtractCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Stigma Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
Saffron Stigma ExtractCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Stigma Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Vita-Mind — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumSkeletal Muscle Relaxants Moderate
Interaction Summary
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Read the full Magnesium + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Vita-Mind — through 3 ingredients. Tap an ingredient for the detail:
MagnesiumSkeletal Muscle Relaxants Moderate
Interaction Summary
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Read the full Magnesium + Acetaminophen, Chlorzoxazone, Codeine interactionSaffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Chlorzoxazone, Codeine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Codeine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Codeine, Doxylamine interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Vita-Mind — through 3 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Codeine, Methocarbamol interactionMagnesiumSkeletal Muscle Relaxants Moderate
Interaction Summary
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Read the full Magnesium + Acetaminophen, Codeine, Methocarbamol interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Vita-Mind — through 2 ingredients. Tap an ingredient for the detail:
Saffron Stigma ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Stigma Extract + Acetaminophen, Dichlorophenazone, Isometheptane interactionGamma-aminobutyric AcidCns Depressants Minor
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gamma-aminobutyric Acid + Acetaminophen, Dichlorophenazone, Isometheptane interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Vita-Mind with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Saffron Stigma Extract
Antidiabetes Drugs
Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Some clinical research shows that taking saffron extract reduces fasting levels of glucose when used in addition to hypoglycemic agents. However, saffron powder itself has not been shown to reduce fasting glucose levels.
Antihypertensive Drugs
Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Animal and human research suggests that saffron extract can decrease blood pressure.
Caffeine
Theoretically, saffron might inhibit the metabolism of caffeine.
A small clinical study suggests that taking saffron powder 300 mg in 150 mL water daily for 5 days and then taking caffeine 200 mg seems to reduce caffeine metabolite levels in the saliva and urine in males, but not females. Theoretically, this may be due to the inhibition of cytochrome P450 1A2 by saffron.
Cns Depressants
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Clinical research shows that taking saffron extract 60 mg orally daily for 26 weeks can cause drowsiness and sedation. Animal research suggests that adding saffron to hexobarbital further increases sleeping and slows motor activity.
Gamma-Aminobutyric Acid
Antihypertensive Drugs
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.
Cns Depressants
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.
Magnesium
Levodopa/Carbidopa (Sinemet)
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Clinical research in healthy volunteers shows that taking magnesium oxide 1000 mg with levodopa 100 mg/carbidopa 10 mg reduces the area under the curve (AUC) of levodopa by 35% and of carbidopa by 81%. In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa.
Aminoglycoside Antibiotics
Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Both aminoglycosides and magnesium reduce presynaptic acetylcholine release, which can lead to neuromuscular blockade and possible paralysis. This is most likely to occur with high doses of magnesium given intravenously.
Antacids
Use of acid reducers may reduce the laxative effect of magnesium oxide.
A retrospective analysis shows that, in the presence of H2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs), a higher dose of magnesium oxide is needed for a laxative effect. This may also occur with antacids. Under acidic conditions, magnesium oxide is converted to magnesium chloride and then to magnesium bicarbonate, which has an osmotic laxative effect. By reducing acidity, antacids may reduce the conversion of magnesium oxide to the active bicarbonate salt.
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)
Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after magnesium containing products.
Bisphosphonates
Magnesium can decrease absorption of bisphosphonates.
Cations, including magnesium, can decrease bisphosphonate absorption. Advise patients to separate doses of magnesium and these drugs by at least 2 hours.
Calcium Channel Blockers
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers. Severe hypotension and neuromuscular blockades may occur when nifedipine is used with intravenous magnesium, although some contradictory evidence suggests that concurrent use of magnesium with nifedipine does not increase the risk of neuromuscular weakness. High doses of magnesium could theoretically have additive effects with other calcium channel blockers.
Digoxin
Magnesium salts may reduce absorption of digoxin.
Clinical evidence suggests that treatment with oral magnesium hydroxide or magnesium trisilicate reduces absorption of digoxin from the intestines. This may reduce the blood levels of digoxin and decrease its therapeutic effects.
Potassium-Sparing Diuretics
Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.
Quinolone Antibiotics
Magnesium decreases absorption of quinolones.
Magnesium can form insoluble complexes with quinolones and decrease their absorption. Advise patients to take these drugs at least 2 hours before, or 4 to 6 hours after, magnesium supplements.
Skeletal Muscle Relaxants
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Parenteral magnesium shortens the time to onset of skeletal muscle relaxants by about 1 minute and prolongs the duration of action by about 2 minutes. Magnesium potentiates the effects of skeletal muscle relaxants by decreasing calcium-mediated release of acetylcholine from presynaptic nerve terminals, reducing postsynaptic sensitivity to acetylcholine, and having a direct effect on the membrane potential of myocytes. Magnesium also has vasodilatory actions and increases cardiac output, allowing a greater amount of muscle relaxant to reach the motor end plate. A clinical study found that low-dose rocuronium (0.45 mg/kg), when given after administration of magnesium 30 mg/kg over 10 minutes, has an accelerated onset of effect, which matches the onset of effect seen with a full-dose rocuronium regimen (0.6 mg/kg). In another clinical study, onset times for rocuronium doses of 0.3, 0.6, and 1.2 mg/kg were 86, 76, and 50 seconds, respectively, when given alone, but were reduced to 66, 44, and 38 seconds, respectively, when the doses were given after a 15-minute infusion of magnesium sulfate 60 mg/kg. Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time. It does not affect the activity of subsequently administered neostigmine.
Sulfonylureas
Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Clinical research shows that administration of magnesium hydroxide with glyburide increases glyburide absorption, increases maximal insulin response by 35-fold, and increases the risk of hypoglycemia, when compared with glyburide alone. A similar interaction occurs between magnesium hydroxide and glipizide. The mechanism of this effect appears to be related to the elevation of gastrointestinal pH by magnesium-based antacids, increasing solubility and enhancing absorption of sulfonylureas.
Tetracycline Antibiotics
Magnesium decreases absorption of tetracyclines.
Magnesium can form insoluble complexes with tetracyclines in the gut and decrease their absorption and antibacterial activity. Advise patients to take these drugs 1 hour before or 2 hours after magnesium supplements.
Anticoagulant/Antiplatelet Drugs
Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
In vitro evidence shows that magnesium sulfate inhibits platelet aggregation, even at low concentrations. Some preliminary clinical evidence shows that infusion of magnesium sulfate increases bleeding time by 48% and reduces platelet activity. However, other clinical research shows that magnesium does not affect platelet aggregation, although inhibition of platelet-dependent thrombosis can occur.
Gabapentin (Neurontin)
Gabapentin absorption can be decreased by magnesium.
Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to take gabapentin at least 2 hours before, or 4 to 6 hours after, magnesium supplements.
Sevelamer (Renagel, Renvela)
Sevelamer may increase serum magnesium levels.
In patients on hemodialysis, sevelamer use was associated with a 0.28 mg/dL increase in serum magnesium. The mechanism of this interaction remains unclear.
Brand information
Manufacturer and brand details for Vita-Mind, from the product label.
Market America
See all Market America products- Name
- Market America, Inc.
- Street Address
- 1302 Pleasant Ridge Road
- City
- Greensboro
- State
- NC
- ZipCode
- 27409
Vita-Mind by Market America: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Vita-Mind’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Magnesium
Interacts with 295 drugsMagnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preventing or correcting deficiency. Some othe...
Read the full Magnesium monograph → Herb & supplement monographGamma-aminobutyric Acid (gaba)
Interacts with 419 drugsGABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...
Read the full Gamma-aminobutyric Acid (gaba) monograph → Herb & supplement monographSaffron
Interacts with 521 drugsSaffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research uses small trials, so results are not defi...
Read the full Saffron monograph →Sources & How We Checked
Vita-Mind's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 116 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Magnesium 82 references
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- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press, 1999. Available at: http://books.nap.edu/books/0309063507/html/index.html.
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Gamma-aminobutyric Acid (gaba) 12 references
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See these in context on the Gamma-aminobutyric Acid (gaba) monograph →
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