Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange Ingredients & Drug Interactions

by Rainbow Light

Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange label
See full label image
Gummy Or Jelly Category: Vitamin
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange is a dietary supplement by Rainbow Light with 1 active ingredient. Its ingredients are commonly taken for bone health and osteoporosis, correcting vitamin d deficiency, immune system support.Based on those ingredients, 715 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D3. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange by Rainbow Light

Ask about any prescription or over-the-counter medication and we check it for interactions with Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange by Rainbow Light — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange by Rainbow Light

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: vitamin D3, a form of vitamin D your body uses to absorb calcium, support bone health, and regulate immune function. The gummy also contains inactive ingredients — cane sugar, glucose syrup, water, gelatin, and several acids and flavoring agents that give it its tangy mandarin orange taste and chewy texture.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: strong bones, teeth, muscles and immune health.
  • We looked for evidence on: Muscle strength, Fall prevention, Fractures, Osteomalacia, Corticosteroid-induced osteoporosis, Hyperparathyroidism-related bone loss — and 4 related terms.
  • The strongest evidence on file: Vitamin D is rated "Effective" for Osteomalacia (Natural Medicines).
  • Also on file: Vitamin D is rated "Effective" for Renal osteodystrophy.
  • Also on file: Vitamin D is rated "Likely Effective" for Corticosteroid-induced osteoporosis.

Vitamin D3 is rated effective for treating rickets, osteomalacia (soft bones from vitamin D deficiency), renal bone disease, hypoparathyroidism, and familial hypophosphatemia — all conditions where vitamin D supplementation is a proven medical treatment. The evidence we hold does not address effectiveness for other uses like general bone health or immunity in otherwise healthy adults.

The evidence, ingredient by ingredient Vitamin D

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin D is generally well tolerated at recommended doses. This product's 400 IU is far below the level that causes toxicity; serious side effects like high blood calcium, bone loss, or eye problems are rare and linked to very high doses taken over time.

Pregnancy and lactation data show vitamin D is likely safe during both, though the safety notes advise using it only under your doctor's guidance during pregnancy. If you're pregnant, breastfeeding, or considering higher doses than recommended, talk it over with your doctor or pharmacist first.

Side effects, ingredient by ingredient Vitamin D

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin D.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 716 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use thiazide diuretics, verapamil, atorvastatin, digoxin, diltiazem, calcipotriene, aluminum-containing antacids, or any CYP3A4 substrate medications. The main concern is that high-dose vitamin D can raise blood calcium and interfere with heart rhythm control; at 400 IU, this risk is low, but it's still worth confirming your medications won't be affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

At 400 IU, this gummy is a low-dose vitamin D supplement suitable for general dietary intake or as part of a treatment plan your doctor recommends for rickets, osteomalacia, or other vitamin D–deficiency conditions. If you take heart rhythm medications, statins, thiazide diuretics, or aluminum-containing antacids, check your specific medications before starting.

Your own doctor or pharmacist can tell you whether this product is right for you and whether it affects your other drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange, straight from the product label.

Brand Rainbow Light
Barcode (UPC) 021888120536
Net contents 0 Not Present
Market status On market
Date entered into DSLD Aug 24, 2023
DSLD ID 289126
Product type Vitamin
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange by Rainbow Light, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gummy(ies)
Maximum serving Sizes:
1 Gummy(ies)
UPC/BARCODE
021888120536
IngredientAmount% DV
Vitamin D310 mcg50%
Added Sugars1 Grain(s)2%
Calories10 Calorie(s)--
Total Carbohydrate2 Gram(s)1%
Total Sugars1 Gram(s)--

Other ingredients: Cane Sugar, Glucose Syrup, Water, Gelatin, Lactic Acid, Citric Acid, Tartaric Acid, Paprika, Natural Flavors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Free of gluten wheat milk/dairy soy nuts eggs fish shellfish yeast artificial additives preservatives.

Protects immune system health Promotes strong bones, teeth & muscles

No artificial colors, flavors, sweeteners or preservatives

Pediatrician-recommended daily value Promotes strong bones & immune health

Gluten-free Soy-free

Formula

Big gummy drop of vitamin D3 sunshine - in a natural tangy orange flavor kids love! Vitamin D is essential to nearly every cell, organ and system of the body, from the bones, teeth and muscles to the immune system, brain and heart. Yet many children don't get enough vitamin D from sunshine or diet alone. As a result, the American Academy of Pediatrics recommends that infants, children and adolescents supplement with 400 IU of vitamin D3 daily.

Easily absorbed vitamin D3

For ages 4 & above

FDA Statement of Identity

Dietary Supplement

General Statements

100% recycled, 100% recyclable, BPA-Free bottle Please remove label to recycle bottle. To open, press along perforation.

Suggested/Recommended/Usage/Directions

Suggested usage: Adults and children over 4, chew 1 gummy per day, with or between meals.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Keep out of reach of children.

Consult your health care professional prior to use if you are pregnant, nursing, taking medication or have medical condition.

Brand IP Statement(s)

Copyright 2019

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange by Rainbow Light label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange by Rainbow Light

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Gummy(ies) Dosage formGummy Or Jelly Amounts shown are per serving.

Vitamin D3

Interacts with
715 drugs
10 mcg per serving Form: Cholecalciferol

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D3 monograph & interactions

Other (inactive) ingredients: Cane Sugar, Glucose Syrup, Water, Gelatin, Lactic Acid, Citric Acid, Tartaric Acid, Paprika, Natural Flavors. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange by Rainbow Light Drug Interactions

Want to check YOUR meds against Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
715Drugs
80 Moderate 635 Minor

Ingredients driving the most interactions

Vitamin D3 715

Individual Drug Interactions

The ingredients in Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange interact with 715 drugs. Click any drug to see the details.

1 of the 1 ingredient in Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange interact with drugs. Each result below shows which ingredient is responsible. Vitamin D3

Each ingredient & the kinds of drugs it affects

For each ingredient in Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin D38 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D
Vitamin D3 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange, from the product label.

Rainbow Light

See all Rainbow Light products
Name
Nutranext Business, LLC
Street Address
1301 Sawgrass Corporate Parkway
City
Sunrise
State
FL
ZipCode
33323
Phone Number
800.571.4701
Web Address
www.rainbowlight.com
Pharmacist Counseling Corner

Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange by Rainbow Light: Common Questions

Does Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange by Rainbow Light interact with any medications?
Yes. Based on its ingredients, Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange has a known interaction with 715 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is 400 IU of vitamin D enough if I have a deficiency?
That depends on your specific condition and your doctor's recommendation. Vitamin D3 is effective for treating rickets, osteomalacia, and other deficiency diseases, but the right dose varies by person. Your doctor can measure your vitamin D levels and tell you whether 400 IU per day is adequate or if you need more.
Can I take this while I'm pregnant or breastfeeding?
Vitamin D is likely safe during pregnancy and breastfeeding at recommended doses, though the safety notes advise using it only under your doctor's guidance when pregnant. Talk with your doctor or pharmacist about whether this dose is right for you during pregnancy or lactation, since your individual needs may differ.
What does this gummy actually do?
Vitamin D3 helps your body absorb calcium and is essential for bone health and immune function. It's effective for treating vitamin D deficiency diseases like rickets and osteomalacia. For otherwise healthy people simply wanting to maintain adequate vitamin D, the evidence we hold doesn't address whether this dose makes a measurable difference.
Are there any side effects from the gummy itself?
At the 400 IU dose in this product, vitamin D is very well tolerated — serious side effects like high blood calcium are rare and typically only happen with very high doses taken over a long time. The gummy itself is made from gelatin, sugars, and flavorings; the main dietary note is the cane sugar and glucose content if you're watching your sugar intake.
Could this interfere with my cholesterol or heart medication?
Possibly, depending on your specific drug. High-dose vitamin D can theoretically reduce how well atorvastatin (Lipitor) works and may interfere with heart rhythm medications like verapamil, diltiazem, or digoxin by raising blood calcium. At 400 IU, the risk is very low, but you should still check your exact medications with your doctor or pharmacist before starting.
Why do the interactions mention 'high-dose' vitamin D when this is only 400 IU?
The concerns in the data focus on doses above 4,000 IU daily, which is much higher than this product provides. At 400 IU, you're unlikely to hit that threshold, but if you take this gummy plus other vitamin D sources or doses, you could accumulate a higher total — so it's still worth checking your combined intake with your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange label
Go deeper

The Full Monographs Behind Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin D

Interacts with 715 drugs

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...

Read the full Vitamin D monograph →
Sources

Sources & How We Checked

Sunny Gummies Vitamin D3 (400 IU) Tangy Mandarin Orange's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin D 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
  3. Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 2001;345:66-7. PubMed
  4. Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
  5. Demontis R, Leflon A, Fournier A, et al. 1 alpha(OH) vitamin D3 increases plasma aluminum in hemodialyzed patients taking AI(OH)3. Clin Nephrol 1986;26:146-9.
  6. Crowe M, Wollner L, Griffiths RA. Hypercalcemia following vitamin D and thiazide therapy in the elderly. Practitioner 1984;228:312-3.
  7. Parfitt AM. Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism. Ann Intern Med 1972;77:557-63. PubMed
  8. Thiazide diuretics and the risk of osteoporosis. Pharmacist's Letter/Prescriber's Letter 2003;19(11):191105.
  9. Moon J. The role of vitamin D in toxic metal absorption. J Am Coll Nutr 1994;13:559-64.
  10. Demontis R, Reissi D, Noel C, et al. Indirect clinical evidence that 1alphaOH vitamin D<SUB>3</SUB> increases the intestinal absorption of aluminum. Clin Nephrol 1989;31:123-7.
  11. Adler AJ, Berlyne GM. Duodenal aluminum absorption in the rat: effect of vitamin D. Am J Physiol 1985;249:G209-13. PubMed
  12. Schwartz JB. Effects of vitamin D supplementation in atorvastatin-treated patients: A new drug interaction with an unexpected consequence. Clin Pharmacol Ther 2009;85:198-203. PubMed
  13. Dietary reference intakes for calcium and vitamin D. Institute of Medicine, November 30, 2010. Available at: http://www.iom.edu/~/media/Files/Report%20Files/2010/Dietary-Reference-Intakes-for-Calcium-and-Vitamin-D/Vitamin%20D%20and%20Calcium%202010%20Repo
  14. Cox KA, Dunn MA. Aluminum toxicity alters the regulation of calbindin-D28k protein and mRNA expression in chick intestine. J Nutr 2001;131:2007-13. PubMed
  15. Escribano, J., Balaguer, A., Pagone, F., Feliu, A., and Roque, I. Figuls. Pharmacological interventions for preventing complications in idiopathic hypercalciuria. Cochrane.Database.Syst.Rev. 2009;(1):CD004754. PubMed
  16. Carlton, S., Clopton, D., and Cappuzzo, K. A. Vitamin D deficiency: appropriate replenishment therapies and the effects of vitamin D toxicity. Consult Pharm 2010;25(3):171-177. PubMed
  17. Wang, H., Xia, N., Yang, Y., and Peng, D. Q. Influence of vitamin D supplementation on plasma lipid profiles: a meta-analysis of randomized controlled trials. Lipids Health Dis. 2012;11:42. PubMed
  18. Turner AN, Carr Reese P, Fields KS, Anderson J, Ervin M, Davis JA, Fichorova RN, Roberts MW, Klebanoff MA, Jackson RD. A blinded, randomized controlled trial of high-dose vitamin D supplementation to reduce recurrence of bacterial vaginosis. Am J Obstet G PubMed
  19. Weiner M, Epstein FH. Signs and symptoms of electrolyte disorders. Yale J Biol Med. 1970;43(2):76-109.
  20. Lappe J, Watson P, Travers-Gustafson D, Recker R, Garland C, Gorham E, Baggerly K, McDonnell SL. Effect of Vitamin D and Calcium Supplementation on Cancer Incidence in Older Women: A Randomized Clinical Trial. JAMA. 2017 Mar 28;317(12):1234-1243. PubMed
  21. Roth DE, Leung M, Mesfin E, Qamar H, Watterworth J, Papp E. Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials. BMJ. 2017;359:j5237. PubMed
  22. Murai IH, Fernandes AL, Sales LP, et al. Effect of a single high dose of vitamin D3 on hospital length of stay in patients with moderate to severe COVID-19: A randomized clinical trial. JAMA. 2021.
  23. Wang Z, Schuetz EG, Xu Y, Thummel KE. Interplay between vitamin D and the drug metabolizing enzyme CYP3A4. J Steroid Biochem Mol Biol 2013;136:54-8. PubMed
  24. Doyle D, Browne U, Brickley A, Murphy D. Vitamin D-induced hypercalcaemia and acute kidney injury in sarcoidosis. BMJ Case Rep 2023;16(1):e250580. PubMed
  25. Williamson A, Martineau AR, Sheikh A, Jolliffe D, Griffiths CJ. Vitamin D for the management of asthma. Cochrane Database Syst Rev 2023;2(2):CD011511. PubMed
  26. Kinesya E, Santoso D, Gde Arya N, et al. Vitamin D as adjuvant therapy for diabetic foot ulcers: Systematic review and meta-analysis approach. Clin Nutr ESPEN 2023;54:137-143. PubMed

See these in context on the Vitamin D monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team