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Dietary supplement

White Peony 1000 mg Ingredients & Drug Interactions

by Remedys Nutrition

White Peony 1000 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking White Peony 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

White Peony 1000 mg is a dietary supplement by Remedys Nutrition with 1 active ingredient. Its ingredients are commonly taken for menstrual cramps and irregular periods, muscle cramps and spasms, anxiety and stress.Based on those ingredients, 813 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are White Peony. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against White Peony 1000 mg by Remedys Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with White Peony 1000 mg by Remedys Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of White Peony 1000 mg by Remedys Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: White Peony root at 1,000 mg per capsule. The capsules also contain three inactive ingredients — cellulose, glycerin, and water — which serve as the capsule material and filler.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Peony product and its label doesn't state a use — see Peony's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for White Peony's effectiveness is not established for the uses we have data on. Our records show insufficient reliable evidence to rate it for aging skin, anal fissures, atherosclerosis, chronic fatigue syndrome, cirrhosis, and migraine headache.

That doesn't mean it doesn't work for these or other purposes — it means the research we hold doesn't yet support those claims.

The evidence, ingredient by ingredient Peony

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

White Peony appears to be generally well tolerated for short-term use, though high-quality safety data are limited. The most common side effects reported with oral use are digestive issues: abdominal bloating, loss of appetite, diarrhea, nausea, and general stomach discomfort.

In one trial, diarrhea occurred in 5% of participants taking a peony supplement three times daily for 24 weeks, compared to 1% on placebo. There is also a case report of easy bruising and bleeding gums in a person taking warfarin who switched brands of a multi-herb Chinese product containing peony.

During pregnancy, the safety data advise against use. While breastfeeding, there isn't enough reliable information to know whether it's safe — talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Peony

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Peony.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 814 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking White Peony, check with your doctor or pharmacist if you take blood thinners (anticoagulants or antiplatelets), hormone replacement therapy, birth control pills, the antipsychotic clozapine (Clozaril), or the anti-seizure drug phenytoin (Dilantin). Additionally, any medication broken down by your liver's CYP1A2 or CYP3A4 pathways may be affected — your pharmacist can confirm whether yours are on that list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

White Peony may be worth considering if you're interested in trying a traditional herb, but the evidence for its effectiveness isn't yet established. If you take blood thinners, hormone therapy, birth control, or drugs metabolized by CYP1A2 or CYP3A4 enzymes — or if you're pregnant or breastfeeding — you'll want to talk this over with your doctor or pharmacist before starting.

Digestive upset is the most likely side effect.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about White Peony 1000 mg, straight from the product label.

Brand Remedys Nutrition
Barcode (UPC) 672299447257
Net contents 60 Vcap(s)
Market status On market
Date entered into DSLD Aug 23, 2022
DSLD ID 272213
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for White Peony 1000 mg by Remedys Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegan Capsule(s)
Maximum serving Sizes:
1 Vegan Capsule(s)
Servings per container
60
UPC/BARCODE
672299447257
IngredientAmount% DV
White Peony1000 mg--

Other ingredients: Cellulose, Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: One capsule daily

Formulation

Made in the USA

Non-GMO Gluten Free No additives No preservatives No dairy No yeast No corn No fillers

Vegan

Quality and potency guaranteed

Immune Mental Reproduction Pharmacist approved

Precautions

Caution: As with any dietary supplement, consult your healthcare practitioner before using this product. Adult use only.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure, or prevent any disease.

Brand IP Statement(s)

Remedys Nutrition Est. 1972 Quality Purity Pride

Formula

White peony 1000 mg per capsule 60000 mg per bottle

General Statements

Two month supply Pharmacist approved Scan here to learn more:

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

White Peony 1000 mg by Remedys Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

White Peony 1000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in White Peony 1000 mg by Remedys Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegan Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

White Peony

Interacts with
813 drugs
1000 mg per serving Form: Paeonia lactiflora

Peony root is a traditional Chinese medicine herb often used for menstrual problems, cramps, and inflammation, frequently as part of combination formu...

White Peony monograph & interactions

Other (inactive) ingredients: Cellulose, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

White Peony 1000 mg by Remedys Nutrition Drug Interactions

Want to check YOUR meds against White Peony 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
813Drugs
813 Moderate

Ingredients driving the most interactions

White Peony 813

Individual Drug Interactions

The ingredients in White Peony 1000 mg interact with 813 drugs. Click any drug to see the details.

1 of the 1 ingredient in White Peony 1000 mg interact with drugs. Each result below shows which ingredient is responsible. White Peony

Each ingredient & the kinds of drugs it affects

For each ingredient in White Peony 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

White Peony7 drug types · 813 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that peony might have antiplatelet, anticoagulant, and antithrombotic effects.

Likelihood Possible Evidence D
Clozapine (Clozaril)

Theoretically, peony might increase the levels and clinical effects of clozapine.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on cytochromes P450 (CYP) 1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, peony might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro and animal research shows that peony extract has estrogenic activity. Concomitant use might also increase the risk for estrogen-related adverse effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of large amounts of peony might interfere with hormone replacement therapy and/or increase the risk for estrogen-related adverse effects.
In vitro and animal research shows that peony extract has estrogenic activity. Theoretically, peony might compete for estrogen receptors and/or cause additive estrogenic effects.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Theoretically, peony might reduce the levels and clinical effects of phenytoin.
Animal research shows that taking peony root reduces levels of phenytoin. Some researchers suggest that peony root might affect cytochrome P450 (CYP) 2C9, which metabolizes phenytoin. However, preliminary research in humans shows that peony root does not alter levels of losartan (Cozaar), which is also metabolized by CYP2C9.

Likelihood Probable Evidence D
White Peony full monograph & interactions
The maker

Brand information

Manufacturer and brand details for White Peony 1000 mg, from the product label.

Remedys Nutrition

See all Remedys Nutrition products
Name
Remedy's Nutrition
Street Address
99696 Overseas Highway Ste 6
City
Key Largo
State
FL
ZipCode
33037
Web Address
www.RMDYS.com
Pharmacist Counseling Corner

White Peony 1000 mg by Remedys Nutrition: Common Questions

Does White Peony 1000 mg by Remedys Nutrition interact with any medications?
Yes. Based on its ingredients, White Peony 1000 mg has a known interaction with 813 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
White Peony 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take White Peony if I'm pregnant or breastfeeding?
No — the safety data advise against use during pregnancy. If you're breastfeeding, there isn't enough reliable information to know whether it's safe, so talk with your doctor or pharmacist before taking it.
What are the most common side effects?
Digestive issues are most likely: stomach bloating, nausea, diarrhea, loss of appetite, and general stomach discomfort. These tend to be mild, but in one trial 5% of people taking peony three times daily reported diarrhea.
Does White Peony actually work for anything?
The evidence we have doesn't yet support claims for aging skin, anal fissures, atherosclerosis, fatigue, cirrhosis, or migraines. That doesn't mean it's ineffective — it means the research backing those uses isn't established in our data.
Why does this product interact with so many medications?
White Peony affects how your liver breaks down drugs and has estrogenic properties. Those two mechanisms together touch a very broad range of common medications — which is why checking your specific prescriptions with your pharmacist is important.
Is White Peony safe to take long-term?
It appears generally well tolerated for short-term use, but high-quality safety data for long-term use are limited. If you're considering regular use, talk it over with your pharmacist or doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if White Peony 1000 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

White Peony 1000 mg label
Go deeper

The Full Monographs Behind White Peony 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Peony

Interacts with 813 drugs

Peony root is a traditional Chinese medicine herb often used for menstrual problems, cramps, and inflammation, frequently as part of combination formulas. Human evidence for most uses is lim...

Read the full Peony monograph →
Sources

Sources & How We Checked

White Peony 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Peony 15 references
  1. Chen LC, Chou MH, Lin MF, Yang LL. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. J Clin Pharm Ther 2001;26:271-8. PubMed
  2. Guo TL, Zhou XW. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707.
  3. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. J Clin Pharm Ther 2002;27:229-30. . PubMed
  4. Harada M, Suzuki M, Ozaki Y. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. J Pharmacobiodyn 1984;7:304-11. PubMed
  5. Anon. Monograph. Peony (Paeonia spp). Alt Med Rev 2001;6:495-9.
  6. Bruynzeel DP. Contact Dermatitis Due to Paeonia (Peony). Contact Dermatitis 1989; 20:152-3..
  7. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. Chin Med J (Engl.) 1998;111(7):585-587.
  8. Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Ann Pharmacother 2003;37(6):836-838.
  9. Cai Y, Yuan Q, Xu K, et al. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2016;2016:8292486.
  10. Koo YK, Kim JM, Koo JY, et al. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Pharmazie 2010;65(8):624-8.
  11. Wang W, Tian DD, Zheng B, et al. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Drug Metab Dispos 2015;43(7):1147-53. PubMed
  12. Zhou Y, Jin L, Kong F, et al. Clinical and immunological consequences of total glucosides of paeony treatment in Sjögren's syndrome: A randomized controlled pilot trial. Int Immunopharmacol. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. PubMed
  13. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. Int Urol Nephrol. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. PubMed
  14. Xu Y, Li X, Chen T, et al. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Phytother Res. 2019;33(1):117-29. [RETRACTED].
  15. Liu X, Li X, Li X, et al. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Clin Rheumatol. 2019;38(3):657-64. Erratum i

See these in context on the Peony monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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