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Dietary supplement

Yarrow Pom Ingredients & Drug Interactions

by doTERRA

Yarrow Pom label
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Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Yarrow Pom against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Yarrow Pom is a dietary supplement by doTERRA with 1 active ingredient. Its ingredients are commonly taken for wounds and minor bleeding, digestive upset and cramping, colds, flu, and fever.Based on those ingredients, 923 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Yarrow | Pom Active Botanical Nutritive Duo. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Yarrow Pom by doTERRA

Ask about any prescription or over-the-counter medication and we check it for interactions with Yarrow Pom by doTERRA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Yarrow Pom by doTERRA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Yarrow | Pom Active Botanical Nutritive Duo” is listed as a grouped ingredient — the label gives one combined amount (60 mg) without saying how much of each component you get.

Yarrow Pom contains 2 active ingredients: a Yarrow and Pomegranate blend, plus pomegranate seed oil. Pomegranate seed oil is the concentrated extract from pomegranate seeds, while the yarrow component includes yarrow oil.

There are no inactive fillers listed for this product.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Topical and internal botanical nutritive support.
  • We looked for evidence on: Wound healing, Dysmenorrhea, Influenza, Hypertension, Hyperlipidemia, Atherosclerosis — and 4 related terms.
  • The strongest evidence on file: Pomegranate is rated "Possibly Effective" for Hypertension (Natural Medicines).
  • Also on file: Pomegranate is rated "Possibly Ineffective" for Hyperlipidemia.
  • Also on file: Yarrow is rated "Insufficient Reliable Evidence To Rate" for Atopic dermatitis (eczema), Wound healing, Dysmenorrhea.

For pomegranate, the data shows it's possibly effective for high blood pressure — some research suggests it can modestly lower blood pressure. However, for cholesterol (hyperlipidemia) and blood sugar control (diabetes), the evidence leans toward possibly ineffective.

For fatty liver disease, there isn't enough reliable evidence to say either way. Yarrow's effectiveness is less clear — the data we hold shows insufficient reliable evidence for tonsillitis, wound healing, eczema, period pain, and yeast infections.

You'd want to talk with your pharmacist or doctor about what you're hoping this product will do for you.

The evidence, ingredient by ingredient Yarrow Pomegranate

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pomegranate fruit and juice are generally well tolerated in normal food amounts. The fruit extract and seed oil seem well tolerated too, though concentrated extracts warrant caution because of limited safety data.

The most common side effects from oral pomegranate are mild — diarrhea and flatulence — occurring in a small number of people who took high-dose extract. Yarrow, taken by mouth or applied vaginally, seems well tolerated, but it can cause allergic skin reactions topically (dermatitis or hives) due to its natural oils.

Human safety data for yarrow are limited. Yarrow is traditionally avoided in pregnancy because it may affect the uterus, and there isn't enough information to recommend it while breastfeeding.

Side effects, ingredient by ingredient Yarrow Pomegranate

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Yarrow, Pomegranate.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; lithium.
  • For scale: 924 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications before you start, especially if you take: blood pressure medications (antihypertensives or ACE inhibitors), blood thinners like warfarin, cholesterol drugs like rosuvastatin, antidepressants or other drugs metabolized by CYP2D6, lithium, anti-seizure medications like carbamazepine, or any drug processed by the liver enzymes CYP2C9 or CYP3A4. These are the drug types documented to interact with pomegranate and yarrow.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with blood pressure, but it interacts with many common medications. If you take blood pressure drugs, blood thinners, cholesterol medications, antidepressants, anti-seizure drugs, or lithium, check with your pharmacist before starting.

Pomegranate and yarrow are generally well tolerated in small amounts, but talk to your pharmacist if you're pregnant, breastfeeding, or taking any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Yarrow Pom, straight from the product label.

Brand doTERRA
Net contents 15 mL; 0.5 fl. Oz.
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 267747
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Yarrow Pom by doTERRA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Drop(s)
Maximum serving Sizes:
2 Drop(s)
Servings per container
125
IngredientAmount% DV
Yarrow | Pom Active Botanical Nutritive Duo60 mg--
Pomegranate Seed Oil0 NP--
Yarrow Oil0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

For topical use. Apply to desired area as needed. No dilution required.

For internal use dilute 2 drops in 4 fl. oz. of liquid.

Precautions

Caution: Keep away from children.

Consult your doctor if pregnant or in treatment.

Avoid eyes, inner ears, and sensitive areas. May stain surfaces and fabrics.

Formulation

Active botanical nutritive duo

CPTG Certified Pure Tested Grade

FDA Statement of Identity

Essential Oil Supplement

General Statements

Exclusive preview size

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Yarrow Pom by doTERRA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Yarrow Pom label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Yarrow Pom by doTERRA

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Drop(s) Dosage formLiquid Servings per container125 Amounts shown are per serving.

Yarrow | Pom Active Botanical Nutritive Duo

Interacts with
1 drug
60 mg per serving

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits a...

Yarrow | Pom Active Botanical Nutritive Duo monograph & interactions
Interaction report

Yarrow Pom by doTERRA Drug Interactions

Want to check YOUR meds against Yarrow Pom?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
923Drugs
356 Moderate 567 Minor

Ingredients driving the most interactions

Yarrow | Pom Active Botanical Nutritive Duo 1

Individual Drug Interactions

The ingredients in Yarrow Pom interact with 923 drugs. Click any drug to see the details.

1 of the 1 ingredient in Yarrow Pom interact with drugs. Each result below shows which ingredient is responsible. Yarrow | Pom Active Botanical Nutritive Duo

Each ingredient & the kinds of drugs it affects

For each ingredient in Yarrow Pom with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Yarrow | Pom Active Botanical Nutritive Duo1 drug type · 1 drug

Lithium

Theoretically, taking yarrow with lithium might increase the levels and adverse effects of lithium.
Animal research shows that yarrow has diuretic activity. Theoretically, due to these potential diuretic effects, yarrow might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Yarrow | Pom Active Botanical Nutritive Duo full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Yarrow Pom, from the product label.

doTERRA

See all doTERRA products
Name
doTERRA Intl, LLC
Street Address
389 South 1300 West
City
Pleasant Grove
State
UT
ZipCode
84062
Pharmacist Counseling Corner

Yarrow Pom by doTERRA: Common Questions

Does Yarrow Pom by doTERRA interact with any medications?
Yes. Based on its ingredients, Yarrow Pom has a known interaction with 923 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Yarrow Pom contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is pomegranate seed oil safe to take while pregnant or breastfeeding?
Pomegranate fruit and juice are rated possibly safe in pregnancy. However, yarrow oil in this product is traditionally avoided in pregnancy because it may affect the uterus, and there isn't enough safety data to recommend it while breastfeeding. Talk with your doctor or pharmacist before using this product if you're pregnant or nursing.
What are the most common side effects from this product?
Pomegranate most commonly causes mild diarrhea and flatulence in a small number of people. Yarrow applied topically can cause allergic skin reactions like dermatitis or hives, but when taken by mouth it seems well tolerated. Most people tolerate both ingredients without problems.
Can pomegranate actually lower blood pressure?
Yes — the data shows pomegranate is possibly effective for high blood pressure and can modestly lower it. That's why it's so important to check with your pharmacist if you already take blood pressure medication; pomegranate could lower your pressure even more.
Will this product help my cholesterol or blood sugar?
The evidence doesn't support pomegranate for cholesterol or blood sugar control — the data shows possibly ineffective for both. If those are your goals, ask your pharmacist or doctor about what might work better.
Are there any fillers or other ingredients in this liquid?
No — the product facts list only the two active ingredients: the yarrow and pomegranate blend and pomegranate seed oil. There are no inactive fillers listed.
Does yarrow have proven benefits?
The evidence isn't established for the conditions we have data on — tonsillitis, wound healing, eczema, period pain, and yeast infections all show insufficient reliable evidence. Talk with your pharmacist about what you're using it for and whether there's better-supported options.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Yarrow Pom label
Go deeper

The Full Monographs Behind Yarrow Pom’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Yarrow

Interacts with 1 drug

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used...

Read the full Yarrow monograph → Herb & supplement monograph

Pomegranate

Interacts with 922 drugs

Pomegranate is a nutrient-rich fruit that is high in antioxidants and is widely enjoyed as food and juice. Early research suggests it may support heart health and blood pressure, but the evi...

Read the full Pomegranate monograph →
Sources

Sources & How We Checked

Yarrow Pom's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 35 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Yarrow 8 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
  4. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
  5. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
  6. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
  7. de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
  8. Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed

See these in context on the Yarrow monograph →

Pomegranate 27 references
  1. Igea JM, Cuesta J, Cuevas M, et al. Adverse reaction to pomegranate ingestion. Allergy 1991;46:472-4. DOI
  2. Gaig P, Bartolome B, Lleonart R, et al. Allergy to pomegranate (Punica granatum). Allergy 1999;54:287-8.
  3. Aviram M, Dornfeld L. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Atherosclerosis 2001;158:195-8. PubMed
  4. Valsecchi R, Reseghetti A, Leghissa P, et al. Immediate contact hypersensitivity to pomegranate. Contact Dermatitis 1998;38:44-5. PubMed
  5. Esmaillzadeh A, Tahbaz F, Gaieni I, et al. Concentrated pomegranate juice improves lipid profiles in diabetic patients with hyperlipidemia. J Med Food 2004;7:305-8. PubMed
  6. Aviram M, Rosenblat M, Gaitini D, et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr 2004;23:423-33. DOI
  7. Hidaka M, Okumura M, Fujita K, et al. Effects of pomegranate juice on human cytochrome p450 3A (CYP3A) and carbamazepine pharmacokinetics in rats. Drug Metab Dispos 2005;33:644-8. PubMed
  8. Loren DJ, Seeram NP, Schulman RN, Holtzman DM. Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury. Pediatr Res 2005;57:858-64. PubMed
  9. Kim ND, Mehta R, Yu W, et al. Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Res Treat 2002;71:203-17. PubMed
  10. Sorokin AV, Duncan B, Panetta R, Thompson PD. Rhabdomyolysis associated with pomegranate juice consumption. Am J Cardiol 2006;98:705-6. PubMed
  11. Farkas D, Oleson LE, Zhao Y, et al. Pomegranate juice does not impair clearance of oral or intravenous midazolam, a probe for cytochrome P450-3A activity: comparison with grapefruit juice. J Clin Pharmacol 2007;47:286-94. PubMed
  12. Yeo C, Shon J, Liu K, et al. The effects of pomegranate juice on the pharmacokinetics of simvastatin in healthy Korean subjects (PI-63). Clin Pharmacol Ther 2006;79:23.
  13. Farkas D, Greenblatt DJ. Influence of fruit juices on drug disposition: discrepancies between in vitro and clinical studies. Expert Opin Drug Metab Toxicol 2008;4:381-93.
  14. Nagata M, Hidaka M, Sekiya H, et al. Effects of pomegranate juice on human cytochrome P450 2C9 and tolbutamide pharmacokinetics in rats. Drug Metab Dispos 2007;35:302-5. PubMed
  15. Komperda KE. Potential interaction between pomegranate juice and warfarin. Pharmacotherapy 2009;29:1002-6. PubMed
  16. Gangemi S, Mistrello G, Roncarolo D, et al. Pomegranate-dependent exercise-induced anaphylaxis. J Investig Allergol Clin Immunol 2008;18:491-2.
  17. Misaka S, Nakamura R, Uchida S, et al. Effect of 2 weeks' consumption of pomegranate juice on the pharmacokinetics of a single dose of midazolam: an open-label, randomized, single-center, 2-period crossover study in healthy Japanese volunteers. Clin Ther PubMed
  18. Jarvis S, Li C, Bogle RG. Possible interaction between pomegranate juice and warfarin. Emerg Med J 2010;27:74-5. PubMed
  19. Esmaillzadeh, A., Tahbaz, F., Gaieni, I., Alavi-Majd, H., and Azadbakht, L. Cholesterol-lowering effect of concentrated pomegranate juice consumption in type II diabetic patients with hyperlipidemia. Int J Vitam.Nutr Res 2006;76(3):147-151. PubMed
  20. Forest, C. P., Padma-Nathan, H., and Liker, H. R. Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study PubMed
  21. Wright, H. and Pipkin F. B. Pomegranates (Punica granatum), kiwifruit (Actinidia deliciosa) and blood pressure: a pilot study. Proceedings of the Nutrition Society 2008;67(8):1.
  22. Sohrab G, Sotoodeh G, Siasi F, et al. Effect of pomegranate juice consumption on blood pressure in type 2 diabetic patients. Iranian Journal of Endocrinology and Metabolism 2008;9:399-405, 470.
  23. Enrique E, Utz M, De Mateo JA, et al. Allergy to lipid transfer proteins: cross-reactivity among pomegranate, hazelnut, and peanut. Ann Allergy Asthma Immunol 2006;96(1):122-3. PubMed
  24. Hanley MJ, Masse G, Harmatz JS, et al. Pomegranate juice and pomegranate extract do not impair oral clearance of flurbiprofen in human volunteers: divergence from in vitro results. Clin Pharmacol Ther 2012;92(5):651-7. PubMed
  25. Paller CJ, Ye X, Wozniak PJ, et al. A randomized phase II study of pomegranate extract for men with rising PSA following initial therapy for localized prostate cancer. Prostate Cancer Prostatic Dis 2013;16(1):50-5. PubMed
  26. Park SJ, Yeo CW, Shim EJ, et al. Pomegranate juice does not affect the disposition of simvastatin in healthy subjects. Eur J Drug Metab Pharmacokinet 2016;41(4):339-44. PubMed
  27. Ross MM, Cherkerzian S, Mikulis ND, et al. A randomized controlled trial investigating the impact of maternal dietary supplementation with pomegranate juice on brain injury in infants with IUGR. Sci Rep. 2021;11(1):3569. PubMed

See these in context on the Pomegranate monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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