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Dietary supplement

Coriander Ingredients & Drug Interactions

by doTERRA

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Coriander is a dietary supplement by doTERRA with 1 active ingredient. Its ingredients are commonly taken for digestive upset and gas, appetite stimulation, mild antimicrobial (topical).Based on those ingredients, 717 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coriander. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Coriander by doTERRA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Coriander” is listed as a grouped ingredient — the label gives one combined amount (60 mg) without saying how much of each component you get.

doTERRA's Coriander Liquid is a single-ingredient product: coriander (Coriandrum sativum), delivered as a liquid extract. There are no inactive ingredients listed for this product.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Coriander product and its label doesn't state a use — see Coriander's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't support a clear rating for coriander for any of the conditions it's marketed for — including anorexia, anxiety, constipation, diabetes, diarrhea, and indigestion (dyspepsia). All of these carry a rating of insufficient reliable evidence, which means the research so far hasn't been strong enough to confirm whether it works.

The evidence, ingredient by ingredient Coriander

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coriander is generally well tolerated when used in normal food amounts. At higher medicinal doses or as an essential oil, safety data is limited, so caution is warranted.

The most common side effects when used topically are contact dermatitis (in sensitive people), itching, and a burning sensation. Orally, it's generally well tolerated, though a rare but serious allergic reaction — anaphylaxis — has been reported, particularly in people with occupational exposure to coriander dust or spice.

If you have a known spice allergy or develop symptoms like rash, swelling, or trouble breathing, stop and seek medical attention. We don't have enough safety data on file to say whether this product is safe during pregnancy or while breastfeeding — talk to your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Coriander

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coriander.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 717 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you take antidiabetes medications (insulin, metformin, sulfonylureas), blood pressure medications (ACE inhibitors, beta blockers, calcium channel blockers, diuretics, and others), sedating medications (sleep aids, anxiety meds, opioids, antihistamines), or photosensitizing drugs (certain antibiotics, heart or arthritis medications). Altogether, these interactions span 717 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

doTERRA's Coriander Liquid is generally well tolerated in food amounts, but at medicinal doses the evidence for its effectiveness hasn't been established. If you take diabetes medications, blood pressure drugs, sedatives, or photosensitizing medications, you'll want to check your specific drugs with your own pharmacist or doctor before starting this product — the interactions could affect how well your medications work.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Coriander, straight from the product label.

Brand doTERRA
Net contents 15 mL; 0.5 Fluid Ounce(s)
Market status On market
Date entered into DSLD Nov 19, 2021
DSLD ID 256736
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Coriander by doTERRA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
1 Drop(s)
Servings per container
250
IngredientAmount% DV
Coriander60 mg--
Coriandrum sativum15 mL--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

For aromatic or topical use.

Diffuse aromatically or, to apply topically, dilute with a carrier oil to minimize skin sensitivity.

For internal use dilute 1 drop in 4 fl oz of liquid.

Precautions

Caution: Possible skin sensitivity.

Keep out of reach of children.

If pregnant or under a doctor's care, consult your physician.

Avoid contact with eyes, inner ears, and sensitive areas.

Formula

Coriandrum sativum 15 ml

FDA Statement of Identity

Essential Oil Supplement

Formulation

CPTG Certified Pure Therapeutic Grade

See for yourself

Coriander by doTERRA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Coriander by doTERRA

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container250 Amounts shown are per serving.

Coriander

Interacts with
717 drugs
60 mg per serving

Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints. As a foo...

Coriander monograph & interactions
Interaction report

Coriander by doTERRA Drug Interactions

Want to check YOUR meds against Coriander?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
717Drugs
717 Moderate

Ingredients driving the most interactions

Coriander 717

Each ingredient & the kinds of drugs it affects

For each ingredient in Coriander with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coriander4 drug types · 717 drugs

Antidiabetes Drugs

Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Evidence from animal research suggests that coriander fruit and coriander extract can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Evidence from animal research suggests that coriander fruit can lower blood pressure.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Evidence from animal research suggests that coriander fruit extract has sedative effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Evidence from in vitro research suggests that coriandrin, a constituent of coriander, has photosensitizing effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Coriander, from the product label.

doTERRA

See all doTERRA products
Name
doTERRA Intl, LLC
Street Address
389 South 1300 West
City
Pleasant Grove
State
UT
ZipCode
84062
Pharmacist Counseling Corner

Coriander by doTERRA: Common Questions

Does Coriander by doTERRA interact with any medications?
Yes. Based on its ingredients, Coriander has a known interaction with 717 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Coriander contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this coriander product actually work for anything?
The evidence we hold doesn't show it works reliably for the conditions it's commonly used for — anorexia, anxiety, constipation, diabetes, diarrhea, and indigestion all lack sufficient reliable evidence. That doesn't mean it can't help, just that it hasn't been studied well enough to confirm it.
Is coriander safe if I'm pregnant or breastfeeding?
We don't have enough safety data on file to say either way. Talk to your doctor or pharmacist — they can give you personalized advice based on your situation and how much you'd be using.
What are the side effects?
Coriander is generally well tolerated. If you use it topically, you might get contact dermatitis, itching, or a burning sensation — especially if you're sensitive. Orally, it's usually fine, but a rare serious allergic reaction (anaphylaxis) has been reported in people exposed to coriander dust or spice occupationally.
Can I use this if I take diabetes medication?
Coriander might lower your blood sugar, which could strengthen your medication's effect and raise the risk of low blood sugar (hypoglycemia). Check with your doctor or pharmacist before starting — they may want to monitor your blood glucose or adjust your dose.
Does this product have fillers or anything else in it?
No — it's coriander liquid with no inactive ingredients listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Coriander is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Coriander label
Sources

Sources & How We Checked

Coriander's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coriander 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  3. Gray, A. M. and Flatt, P. R. Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br.J Nutr. 1999;81(3):203-209.
  4. Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
  5. Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370. PubMed
  6. Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
  7. Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., and Bahar, K. Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin-induced diabetic rats. Phytother.Res
  8. Jabeen, Q., Bashir, S., Lyoussi, B., and Gilani, A. H. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. J Ethnopharmacol. 2-25-2009;122(1):123-130. PubMed
  9. van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
  10. Ashwood-Smith, M. J., Warrington, P. J., Jenkins, M., Ceska, O., and Romaniuk, P. J. Photobiological properties of a novel, naturally occurring furoisocoumarin, coriandrin. Photochem.Photobiol. 1989;50(6):745-751. PubMed
  11. Sastre, J., Olmo, M., Novalvos, A., Ibanez, D., and Lahoz, C. Occupational asthma due to different spices. Allergy 1996;51(2):117-120. PubMed
  12. Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. PubMed

See these in context on the Coriander monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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