No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 7 ingredients. Check your meds →
Dietary supplement

ZyCarb Ingredients & Drug Interactions

by Houston Enzymes

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

ZyCarb is a dietary supplement by Houston Enzymes with 7 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of ZyCarb by Houston Enzymes

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.

ZyCarb contains seven active digestive enzymes. Lactase breaks down milk sugar; lipase helps digest fats; protease SP breaks down proteins; and the others — amylase, glucoamylase, alpha-galactosidase, and xylanase — work on starches and complex carbohydrates.

The capsule also holds microcrystalline cellulose and medium-chain triglycerides as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestion of carbohydrates, starches, fiber, and dairy.
  • We looked for evidence on: Lactose intolerance, Dyspepsia, gas and bloating, carbohydrate malabsorption.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase is effective for lactose intolerance — that's the one with solid evidence. For the other enzymes in this product, the evidence isn't established.

Lipase and protease have insufficient reliable evidence for the digestive conditions we reviewed, and the remaining three aren't rated in our data. If you're taking ZyCarb for something other than lactose intolerance, talk with your pharmacist about whether the evidence supports that use.

The evidence, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase, lactase, and protease SP are generally well tolerated for most adults. Rare allergic reactions to protease have been reported in occupational settings.

For pregnancy, the data is thin: lactase is likely safe, but lipase and protease are not well studied, so check with your doctor before using them while pregnant. Breastfeeding safety data is also limited for lipase and protease; ask your pharmacist or doctor first.

Premature infants should not receive certain versions of lipase because of a risk of serious bowel injury, though this product's formulation would need to be verified with the manufacturer.

Side effects, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Amylase, glucoamylase, alpha-galactosidase, and xylanase were not checked against drug databases, so use the medication checker on this page to verify your exact prescriptions and supplements.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

ZyCarb is mainly useful if you have lactose intolerance — that's where the evidence is strongest. If you're using it for other digestive complaints, talk with your pharmacist about whether it's the right fit.

Anyone with a serious digestive condition should use it only under medical guidance. Pregnant or breastfeeding?

Check with your doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ZyCarb, straight from the product label.

Brand Houston Enzymes
Barcode (UPC) 898631000250
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Apr 11, 2022
DSLD ID 261882
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ZyCarb by Houston Enzymes, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
898631000250
IngredientAmount% DV
Amylase0 NP--
Lipase0 NP--
Lactase0 NP--
Glucoamylase0 NP--
Alpha-Galactosidase0 NP--
Xylanase0 NP--
Protease SP0 NP--

Other ingredients: Capsule, Microcrystalline Cellulose, Medium Chain Triglycerides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

ZyCarb may be helpful for the digestion of complex carbohydrates, starches and fiber.

ZyCarb also lends support for digestion of certain triglyceride fats and food proteins. Helps prevent occasional gas and bloating from starches in vegetables, dairy, beans and grains.

All vegetarian

Enzyme for digestive support Supports digestion of carbohydrates and fiber Helps occasional gas and bloating from starches

Formula

Includes lactase to help those intolerant to lactose.

Dr. Houston's Biochemist formulated enzymes

Includes lactase enzyme for lactose intolerance

Suggested/Recommended/Usage/Directions

Suggested use: One (1) capsule at the beginning of each meal. Capsules may be opened and contents mixed with food or beverage. Use care not to inhale enzyme powder. ZyCarb may be taken with other Houston Enzymes products.

General Statements

ZyCarb was developed by Dr. Devin Houston, PhD Enzyme Biochemist

Precautions

Do not use if tamper-proof seal is broken.

To report adverse event, contact distributor: Houston Nutraceuticals, Inc. (HNI)

Storage

Keep container closed and store at room temperature or in freezer, but do not place in refrigerator due to humid conditions.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

The authority on enzymes

FDA Statement of Identity

Dietary Supplement

See for yourself

ZyCarb by Houston Enzymes label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in ZyCarb by Houston Enzymes

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Amylase

0 NP per serving

Lipase

No known
interactions
0 NP per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Lactase

No known
interactions
0 NP per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase monograph & interactions

Glucoamylase

0 NP per serving

Alpha-Galactosidase

0 NP per serving

Xylanase

0 NP per serving

Protease SP

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease SP monograph & interactions

Other (inactive) ingredients: Capsule, Microcrystalline Cellulose, Medium Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.

Interaction report

ZyCarb by Houston Enzymes Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in ZyCarb. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for ZyCarb, from the product label.

Houston Enzymes

See all Houston Enzymes products
Name
Houston Nutraceuticals, Inc. (HNI)
Street Address
116 N. Broadway St.
City
Siloam Springs
State
AR
ZipCode
72761
Phone Number
866-757-8627
Web Address
www.houston-enzymes.com
Pharmacist Counseling Corner

ZyCarb by Houston Enzymes: Common Questions

Does ZyCarb by Houston Enzymes interact with any medications?
We do not currently list a known interaction for the mapped ingredients in ZyCarb. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
ZyCarb contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will ZyCarb help with lactose intolerance?
Yes — lactase, one of the enzymes in this product, is effective for lactose intolerance. The other enzymes' effects on digestion aren't well established.
Is it safe to take ZyCarb if I'm pregnant?
The data is mixed. Lactase is likely safe, but lipase and protease have little safety information from pregnancy. Check with your doctor before starting.
Can I take ZyCarb while breastfeeding?
Lactase is probably okay, but lipase and protease haven't been well studied in breastfeeding. Ask your doctor or pharmacist for personalized advice.
What are the side effects?
Most people tolerate it well. Rare allergic reactions to protease have been reported in people exposed to it at work, but cases in supplement users are uncommon. Serious bowel injury is a known risk only in premature infants given certain lipase products.
Is ZyCarb safe for people with digestive conditions?
If you have a serious digestive condition, use it only under medical guidance. Lipase needs extra caution in that setting.
What do these enzymes do?
They break down different foods: lactase handles milk sugar, lipase breaks down fats, protease works on proteins, and the others digest starches and complex carbs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ZyCarb is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ZyCarb label
Sources

Sources & How We Checked

ZyCarb's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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