Lypazyme Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Lypazyme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Lypazyme is a dietary supplement by Houston Enzymes with 3 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Lypazyme by Houston Enzymes
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Lypazyme has 3 active ingredients, all lipases — enzymes that help break down fats during digestion. The product packages them together in what's called the Lypazyme Blend.
Beyond those three lipases, the capsule itself contains microcrystalline cellulose (a binder), hypromellose (a capsule coating), and water.
Does it work?
Not established
The evidence for lipase in treating inflammatory bowel disease, indigestion (dyspepsia), or prematurity is not established in the data we hold — all three conditions are rated as having insufficient reliable evidence. This doesn't mean lipase doesn't work; it means the research so far hasn't been strong enough to draw firm conclusions.
How safe is it?
Well-documented data
Lipase is generally well tolerated in supplement form in adults, though no thorough safety assessment has been done. If you have a serious digestive condition, use it only under medical guidance.
For pregnancy, there's little safety data on supplemental lipase — your doctor should weigh the decision based on your situation. Breastfeeding safety hasn't been well studied either, so check with your healthcare provider first.
In premature infants given recombinant lipase formulations, rare serious digestive effects have been reported, including severe abdominal symptoms and necrotizing enterocolitis (serious intestinal inflammation); this product is not intended for that use.
Meds to double-check
No known interactions
No interactions are documented in our data for the lipase ingredients in Lypazyme. Even so, it's always smart to mention any new supplement to your doctor or pharmacist, especially if you take prescription drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
Lypazyme is a lipase enzyme blend that's generally well tolerated in adults, though the evidence for treating specific digestive or inflammatory conditions isn't established yet. If you have serious digestive disease, are pregnant or breastfeeding, or take medications, talk with your doctor or pharmacist before starting it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Lypazyme, straight from the product label.
| Brand | Houston Enzymes |
|---|---|
| Barcode (UPC) | 898631000427 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2023 |
| DSLD ID | 295280 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Lypazyme by Houston Enzymes, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lypazyme Blend | 40 mg | -- |
| Lipase 1 | 0 NP | -- |
| Lipase 2 | 0 NP | -- |
| Lipase 3 | 0 NP | -- |
Other ingredients: Microcrystalline Cellulose, Hypromellose, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
To report an adverse event, contact Distributor Houston Nutraceuticals, Inc. (HNI) (Distributor) 116 N. Broadway St. Siloam Springs, AR 72761 866-757-8627 www.houston-enzymes.com
Do not use if tamper-proof seal is broken.
Formula
Lypazyme uses 3 forms lipase enzymes to break down the triglyceride fats found in food and many supplements. Using only 1 type of lipase may result in formation of mono- and diglycerides rather than complete breakdown into nutritional short-chain fatty acids. Lypazyme may be used with diets high and fat intake, such as the ketogenic diet.
Enzyme for fat digestion
Supports the Keto Diet
Suggested/Recommended/Usage/Directions
Suggested use: One (1) capsule at the beginning of each meal. Capsules may be opened and contents mixed with food or beverage. Small capsule size (#3) - Easy to swallow.
General Statements
Lypazyme was developed by Dr. Devin Houston, PhD Enzyme Biochemist
Dr. Houston's Biochemist Formulated enzymes
Storage
Keep container closed and store at room temperature or in freezer, but do not place in refrigerator due to humid conditions.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
All vegetarian
Digests fats in foods Small capsule size
Brand IP Statement(s)
Houston Enzymes The authority on enzymes
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Lypazyme by Houston Enzymes label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Lypazyme by Houston Enzymes
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Water. These complete the product’s ingredient list but are not active constituents.
Lypazyme by Houston Enzymes Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Lypazyme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Lypazyme, from the product label.
Houston Enzymes
See all Houston Enzymes products- Name
- Houston Nutraceuticals, Inc. (HNI)
- Street Address
- 116 N. Broadway St.
- City
- Siloam Springs
- State
- AR
- ZipCode
- 72761
- Phone Number
- 866-757-8627
- Web Address
- www.houston-enzymes.com
Lypazyme by Houston Enzymes: Common Questions
Does Lypazyme by Houston Enzymes interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does lipase actually help with indigestion?
Can I take this while pregnant?
Is it safe to take while breastfeeding?
What exactly is lipase?
Will this help with inflammatory bowel disease?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Lypazyme is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Lypazyme’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Lypazyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 1 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC