Interaction check not available yet — this product's ingredients haven't been matched to our database.
Dietary supplement

No-Fenol Chewable Ingredients & Drug Interactions

by Houston Enzymes

Tablet Or Pill Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

No-Fenol Chewable is a dietary supplement by Houston Enzymes with 2 active ingredients.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of No-Fenol Chewable by Houston Enzymes

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 4 active ingredients.
  • “Enzyme Blend” is a proprietary blend — the label gives one combined amount (332 mg) without saying how much of each component you get.
  • “Xylanase” is listed as a grouped ingredient — the label gives one combined amount (32,000 XU) without saying how much of each component you get.

No-Fenol Chewable contains 4 active ingredients: an enzyme blend, xylanase, beta-glucanase, phytase, and hemicellulase — all designed to support carbohydrate and fiber digestion. These are plant-derived enzymes meant to help break down complex carbohydrates, proteins, and plant cell walls so your digestive tract can absorb nutrients more easily.

The product also includes several inactive ingredients — isomaltose, natural flavor, stearic acid, citric acid, magnesium stearate, and stevia — which function as sweeteners, binders, and flow agents in the tablet.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestion of phenolic foods and fiber.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence supporting these enzymes for their intended uses isn't established in the data we hold. Phytase — one of the active ingredients — has been studied for aging skin, iron deficiency anemia, zinc deficiency, child growth, and a neurologic condition called blepharospasm, but in each case the evidence was rated insufficient to draw a firm conclusion about whether it works.

The facts don't provide effectiveness data for the other enzyme components of this product.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phytase is generally considered low-risk in foods, but human supplement data are limited, so there isn't enough reliable information to rule out concerns entirely. There are reports of allergic and respiratory reactions in workers exposed to airborne phytase powder in animal-feed facilities — for instance, some people developed asthma or a lung inflammation condition called hypersensitivity pneumonitis — though this typically happened with occupational inhalation, not oral supplement use.

The safety data for pregnancy and breastfeeding aren't well studied. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product — they can help you weigh what you know about your individual health against any possible risks.

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check in this product.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

No-Fenol Chewable is an enzyme supplement aimed at people who want support for digesting complex carbohydrates and fiber. Since no interactions are documented for the ingredients we checked, it's unlikely to interfere with most medications — but that's not a green light for everyone.

If you take prescription drugs or have questions about whether this product fits your health situation, check with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about No-Fenol Chewable, straight from the product label.

Brand Houston Enzymes
Barcode (UPC) 898631000236
Net contents 180 Chewable Tablet(s)
Market status On market
Date entered into DSLD May 23, 2014
DSLD ID 33807
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for No-Fenol Chewable by Houston Enzymes, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
90
UPC/BARCODE
898631000236
IngredientAmount% DV
Enzyme Blend332 mg--
Xylanase32000 XU--
Beta-Glucanase0 NP--
Phytase0 NP--
Hemicellulase0 NP--
CereCalase(R)75 mg--

Other ingredients: Isomaltose, Natural flavor, Stearic Acid, Citric Acid, Magnesium Stearate, Stevia

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Keep container closed and store at room temperature or in freezer, but do not place in refrigerator due to humid conditions.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

VEGETARIAN AND VEGAN FORMULA

Brand IP Statement(s)

The AUTHORITY on Enzymes.(TM)

CereCalase(R) is a registered trademark of National Enzyme Company.

Seals/Symbols

HCI

DR. HOUSTON'S HIGHEST QUALITY PLANT ENZYMES

General Statements

Multi-Enzyme Produt for Digestion of Phenolic Foods and Fiber

HIGHEST QUALITY ENZYMES SUPPORT DIGESTION

No-Fenol Chewable from HOUSTON ENZYMES

No-Fenol may be helpful for digestion of those foods high in phenols and salcytates. Digestion of fruits and vegetables may also be enhanced as No-Fenol contains enzymes that break down the components of plant fibers. No-Fenol was developed by Dr. Devin Houston, PhD enzyme biochemist.

FDA Statement of Identity

Dietary Supplement

Formula

This product contains cellulase, which may interfere with sustained-release medications that use cellulose, hydroxypropyl cellulose, and/or hypromellose.

Precautions

This product contains cellulase, which may interfere with sustained-release medications that use cellulose, hydroxypropyl cellulose, and/or hypromellose.

Do not use if tamper-proof seal is broken.

General

ITEM NO. HN003-T180 REV 04/11

Suggested/Recommended/Usage/Directions

SUGGESTED USE: Two (2) tablets prior to meals. For smaller meals, one (1) tablet may be adequate. More tablets may be taken as desired. Two (2) chewable tablets are equivalent to one (1) No-Fenol in capsule form. Tablets may be crushed, using care not to inhale enzyme powder.

See for yourself

No-Fenol Chewable by Houston Enzymes label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in No-Fenol Chewable by Houston Enzymes

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Enzyme Blend

332 mg per serving
  • › Xylanase
  • › CereCalase(R)

Other (inactive) ingredients: Isomaltose, Natural flavor, Stearic Acid, Citric Acid, Magnesium Stearate, Stevia. These complete the product’s ingredient list but are not active constituents.

Interaction report

No-Fenol Chewable by Houston Enzymes Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in No-Fenol Chewable. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for No-Fenol Chewable, from the product label.

Houston Enzymes

See all Houston Enzymes products
Name
Houston Nutraceuticals, Inc. (HNI)
Street Address
116 N. Broadway St.
City
Siloam Springs
State
AR
ZipCode
72761
Phone Number
866-757-8627
Web Address
www.houston-enzymes.com
Pharmacist Counseling Corner

No-Fenol Chewable by Houston Enzymes: Common Questions

Does No-Fenol Chewable by Houston Enzymes interact with any medications?
We do not currently list a known interaction for the mapped ingredients in No-Fenol Chewable. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
No-Fenol Chewable contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does this enzyme blend actually do?
The enzymes in No-Fenol Chewable are designed to break down complex carbohydrates, fiber, and plant cell walls so your body can digest and absorb them more easily. Each enzyme targets a different component — phytase breaks down phytic acid found in plants, xylanase targets plant fibers called xylans, and hemicellulase works on the outer plant cell structure.
Are there any ingredients I should know I'm allergic or sensitive to?
The product is sweetened with stevia and contains natural flavor, stearic acid, citric acid, and magnesium stearate as inactive ingredients. If you have a known sensitivity to any of those, check the full ingredient list. There are also reports of allergic reactions to phytase powder in occupational settings, though oral supplement use is different — if you've had respiratory or allergic reactions to enzyme powders before, mention that to your doctor or pharmacist.
Does this work for iron or zinc deficiency?
Phytase, one of the active ingredients, has been studied for zinc and iron deficiency, but the evidence isn't strong enough to say whether it actually works for those conditions. If you have a diagnosed deficiency, talk with your doctor or pharmacist about what the data supports — this product alone may not be the answer.
Can I take this if I'm pregnant or breastfeeding?
The safety data for pregnancy and breastfeeding haven't been well studied for phytase, and there's not enough reliable information to say either way. If you're pregnant, planning to become pregnant, or breastfeeding, check with your doctor or pharmacist for personalized advice before taking this product.
What are the side effects?
Human supplement data are limited, so we don't have a clear picture of how often side effects occur when taken by mouth. The main concern on record comes from workers exposed to phytase powder in factories, where some developed allergic reactions or lung inflammation — but that's from breathing in powder, not taking a chewable tablet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if No-Fenol Chewable is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

No-Fenol Chewable label
Sources

Sources & How We Checked

No-Fenol Chewable's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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