Interaction check not available yet — this product's ingredients haven't been matched to our database.
Dietary supplement

No-Fenol Ingredients & Drug Interactions

by Houston Enzymes

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

No-Fenol is a dietary supplement by Houston Enzymes with 2 active ingredients.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of No-Fenol by Houston Enzymes

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (288 mg) without saying how much of each component you get.
  • “CereCalase” is listed as a grouped ingredient — the label gives one combined amount (75 mg) without saying how much of each component you get.

No-Fenol contains 4 active enzyme ingredients: Beta-Glucanase, Phytase, Xylanase, and Hemicellulase, plus proprietary enzyme blends (CereCalase and a Proprietary Enzyme Blend) whose complete compositions aren't listed on the label. These are digestive enzymes meant to help break down plant cell walls and starches during digestion.

The product also contains inactive ingredients — hypromellose (a capsule material), water, microcrystalline cellulose, and medium chain triglyceride powder — which are fillers and binders, not active components.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestion of polyphenols and plant fibers.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence we hold doesn't establish that Phytase works for the uses sometimes mentioned — aging skin, iron deficiency anemia, zinc deficiency, child growth, or blepharospasm — because our data rates all of these as insufficient reliable evidence to rate. For the other active ingredients (Beta-Glucanase, Xylanase, and Hemicellulase), we don't hold effectiveness data.

This product's actual intended use — digestive support — isn't addressed in the ratings we have on file.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phytase is generally considered low-risk in foods, but human supplement safety data are limited. The safety information for pregnancy is incomplete — we don't have enough data to say it's safe or unsafe, so if you're pregnant or planning to become pregnant, talk with your doctor before taking it.

Breastfeeding safety also hasn't been well studied; use caution and check with a doctor. One concern from occupational exposure: workers exposed to airborne powdered phytase have reported allergic reactions including occupational asthma and a lung inflammation called hypersensitivity pneumonitis (in one documented case after months of exposure).

You won't inhale powder from a capsule, but if you're sensitive to enzymes or have a history of respiratory allergies, mention this product to your doctor first.

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, because Beta-Glucanase, Xylanase, and Hemicellulase aren't in our database, and because the product contains proprietary enzyme blends we can't fully assess, use the medication search tool below to double-check your current drugs before taking this.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a digestive enzyme blend intended to help break down plant material and carbohydrates. Because we can't fully verify the safety and interaction profile of all the ingredients — especially the proprietary blends — and because three of the named enzymes aren't in our database, it's a good idea to check your specific medications with the tool on this page before you start.

If you have a history of respiratory allergies or are pregnant or breastfeeding, talk with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about No-Fenol, straight from the product label.

Brand Houston Enzymes
Barcode (UPC) 898631000274
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2023
DSLD ID 295281
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for No-Fenol by Houston Enzymes, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
898631000274
IngredientAmount% DV
Beta-Glucanase0 NP--
Phytase0 NP--
Xylanase0 NP--
Hemicellulase0 NP--
Proprietary Enzyme Blend288 mg--
CereCalase75 mg--

Other ingredients: Hypromellose, Water, Microcrystalline Cellulose, Medium Chain Triglyceride, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

No-Fenol May be helpful for digestion of those foods high in polyphenols. Digestion of fruits and vegetables may also be enhanced as No-Fenol includes enzymes that breakdown the components of plant fibers.

This product includes hemicellulase, which may interfere with sustained-release medications that use cellulose, hydroxypropyl cellulose, and/or hypromellose as part of the time-release mechanism.

Dr. Houston's Biochemist Formulated Enzymes

Enzyme for polyphenolic foods

Suggested/Recommended/Usage/Directions

Suggested use: One (1) capsule at the beginning of each meal. Capsules may be opened and contents mixed with food or beverage. Use care not to inhale enzyme powder. No-Fenol Maybe taken with other Houston enzymes products.

General Statements

No-Fenol was developed by Dr. Devin Houston, PhD Enzyme Biochemist

Dr. Houston's Biochemist Formulated Enzymes

Precautions

Do not use if tamper-proof seal is broken.

To report and adverse event, contact distributor:

Storage

Keep container closed and store at room temperature or in freezer, but do not place in refrigerator due to humid conditions.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

All vegetarian

Supports digestion of foods high in polyphenols Enhances breakdown of fruit and vegetable fiber

Brand IP Statement(s)

The Authority on Enzymes

CereCalase is a registered trademark of Deerland Probiotic & enzymes.

FDA Statement of Identity

Dietary Supplement

See for yourself

No-Fenol by Houston Enzymes label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in No-Fenol by Houston Enzymes

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Enzyme Blend

288 mg per serving
  • › Xylanase
  • › CereCalase

Other (inactive) ingredients: Hypromellose, Water, Microcrystalline Cellulose, Medium Chain Triglyceride, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

No-Fenol by Houston Enzymes Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in No-Fenol. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for No-Fenol, from the product label.

Houston Enzymes

See all Houston Enzymes products
Name
Houston Nutraceuticals, Inc. (HNI)
Street Address
116 N. Broadway St.
City
Siloam Springs
State
AR
ZipCode
72761
Phone Number
866-757-8627
Web Address
www.houston-enzymes.com
Pharmacist Counseling Corner

No-Fenol by Houston Enzymes: Common Questions

Does No-Fenol by Houston Enzymes interact with any medications?
We do not currently list a known interaction for the mapped ingredients in No-Fenol. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
No-Fenol contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are these enzymes supposed to do?
They're digestive enzymes designed to break down complex carbohydrates and plant cell walls (cellulose and hemicellulose) during digestion, potentially making nutrients more available. The product is labeled as a digestive support supplement.
Is it safe to take if I'm pregnant?
We don't have enough reliable safety data on Phytase during pregnancy to say yes or no. Talk with your doctor before taking it if you're pregnant or planning to become pregnant.
What about while breastfeeding?
Safety while breastfeeding hasn't been well studied. Use caution and check with your doctor before starting this product if you're nursing.
Can I be allergic to the enzymes?
Yes. Occupational exposure to powdered phytase has caused allergic reactions and lung inflammation in some workers. If you have a history of enzyme sensitivities or respiratory allergies, mention this product to your doctor before taking it.
What are the inactive ingredients?
The capsule is made of hypromellose, and it contains water, microcrystalline cellulose (a binder), and medium chain triglyceride powder as fillers. None of these are active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if No-Fenol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

No-Fenol label
Sources

Sources & How We Checked

No-Fenol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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