ZyCarb Ingredients & Drug Interactions
What is this page for?
First and foremost: checking ZyCarb against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
ZyCarb is a dietary supplement by Houston Enzymes with 7 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of ZyCarb by Houston Enzymes
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
ZyCarb is a blend of 7 active digestive enzymes designed to help break down food. You're getting amylase (breaks down starches), lipase (breaks down fats), lactase (breaks down milk sugar), glucoamylase, alpha-galactosidase, xylanase, and protease SP (breaks down proteins).
The capsule itself is filled with microcrystalline cellulose and medium chain triglycerides as inactive ingredients to hold everything together.
Does it work?
Strong evidence
Lactase in this product is effective for lactose intolerance — if you have trouble digesting milk sugar, that ingredient has solid evidence behind it. For the other enzymes and what the overall blend may do for general digestion, the evidence we hold is insufficient to say whether they work.
Dyspepsia (indigestion), inflammatory bowel disease, and other digestive conditions lack reliable evidence for lipase and protease SP in supplement form.
How safe is it?
Well-documented data
The enzymes in ZyCarb are generally well tolerated in adults when used as directed. Rare cases of allergic reactions to proteolytic enzymes have been reported in occupational settings with airborne exposure; one case of contact dermatitis to lactase powder was documented in a worker.
If you have a serious digestive condition, check with your doctor before starting — these enzymes work best under medical guidance in those cases. For pregnancy: there isn't enough safety data on lipase and protease SP to know either way, so talk with your doctor before using regularly.
Lactase is likely safe in pregnancy. For breastfeeding, data is limited for lipase and protease SP — ask your doctor or pharmacist for personalized advice.
Don't use protease SP during pregnancy unless your doctor prescribes it.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That said, we couldn't verify four of the seven enzymes in this product, so if you take any medications, use the search tool on this page to be sure, or ask your pharmacist.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
ZyCarb is a straightforward enzyme blend most useful if you have lactose intolerance or need digestive support under a doctor's care. If you take prescription medications, check them against the tool on this page first, or ask your pharmacist.
If you're pregnant, breastfeeding, or have a serious digestive condition, talk it over with your doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about ZyCarb, straight from the product label.
| Brand | Houston Enzymes |
|---|---|
| Barcode (UPC) | 898631000250 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 11, 2022 |
| DSLD ID | 261882 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for ZyCarb by Houston Enzymes, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Alpha-Galactosidase | 0 NP | -- |
| Xylanase | 0 NP | -- |
| Protease SP | 0 NP | -- |
Other ingredients: Capsule, Microcrystalline Cellulose, Medium Chain Triglycerides
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
ZyCarb may be helpful for the digestion of complex carbohydrates, starches and fiber.
ZyCarb also lends support for digestion of certain triglyceride fats and food proteins. Helps prevent occasional gas and bloating from starches in vegetables, dairy, beans and grains.
All vegetarian
Enzyme for digestive support Supports digestion of carbohydrates and fiber Helps occasional gas and bloating from starches
Formula
Includes lactase to help those intolerant to lactose.
Dr. Houston's Biochemist formulated enzymes
Includes lactase enzyme for lactose intolerance
Suggested/Recommended/Usage/Directions
Suggested use: One (1) capsule at the beginning of each meal. Capsules may be opened and contents mixed with food or beverage. Use care not to inhale enzyme powder. ZyCarb may be taken with other Houston Enzymes products.
General Statements
ZyCarb was developed by Dr. Devin Houston, PhD Enzyme Biochemist
Precautions
Do not use if tamper-proof seal is broken.
To report adverse event, contact distributor: Houston Nutraceuticals, Inc. (HNI)
Storage
Keep container closed and store at room temperature or in freezer, but do not place in refrigerator due to humid conditions.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
The authority on enzymes
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
ZyCarb by Houston Enzymes label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in ZyCarb by Houston Enzymes
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Amylase
Lipase
No knowninteractions
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...
Lipase monograph & interactionsLactase
No knowninteractions
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...
Lactase monograph & interactionsGlucoamylase
Alpha-Galactosidase
Xylanase
Protease SP
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease SP monograph & interactionsOther (inactive) ingredients: Capsule, Microcrystalline Cellulose, Medium Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.
ZyCarb by Houston Enzymes Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in ZyCarb. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for ZyCarb, from the product label.
Houston Enzymes
See all Houston Enzymes products- Name
- Houston Nutraceuticals, Inc. (HNI)
- Street Address
- 116 N. Broadway St.
- City
- Siloam Springs
- State
- AR
- ZipCode
- 72761
- Phone Number
- 866-757-8627
- Web Address
- www.houston-enzymes.com
ZyCarb by Houston Enzymes: Common Questions
Does ZyCarb by Houston Enzymes interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does ZyCarb actually help with lactose intolerance?
Is it safe to take ZyCarb if I'm pregnant?
Can I take ZyCarb while breastfeeding?
What are these enzymes actually supposed to do?
Are there any side effects I should know about?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if ZyCarb is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind ZyCarb’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
ZyCarb's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC