Zyme Prime Chewable Pomegranate Raspberry Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Zyme Prime Chewable Pomegranate Raspberry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Zyme Prime Chewable Pomegranate Raspberry is a dietary supplement by Houston Enzymes with 9 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Zyme Prime Chewable Pomegranate Raspberry by Houston Enzymes
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
Zyme Prime contains nine active enzymes designed to support digestion. Lipase breaks down fats, lactase handles dairy sugars, and protease 4.5 works on proteins; amylase, glucoamylase, and alpha-galactosidase all help with carbohydrate digestion.
Phytase, beta-glucanase, and hemicellulase round out the blend to address other harder-to-digest plant compounds. The tablet also contains inactive ingredients — fructose, xylitol, microcrystalline cellulose, hydroxypropyl cellulose, magnesium stearate, silica, and citric acid — along with natural pomegranate and raspberry flavoring.
Does it work?
Strong evidence
The evidence we hold shows that lactase is effective for lactose intolerance — if you have trouble digesting dairy, this enzyme can help. For the other active ingredients in this blend — lipase, phytase, protease, and the rest — the evidence isn't established in our data.
That doesn't mean they don't work; it means the studies either aren't strong enough yet or we haven't reviewed them in detail. Talk with your doctor or pharmacist about whether this product matches what you're trying to do.
How safe is it?
Well-documented data
Lipase, lactase, and protease 4.5 are generally well tolerated when used as directed, though some people may experience mild digestive upset or allergic reactions — rare, but possible. Phytase comes with a caution: occupational exposure to airborne powdered phytase in animal-feed workers has triggered allergic asthma and hypersensitivity pneumonitis, so if you have a history of respiratory allergies or sensitivities, be aware.
For pregnancy, lactase is likely safe, but lipase, phytase, and protease 4.5 lack enough data — talk with your doctor before using during pregnancy or breastfeeding. We hold no pregnancy or breastfeeding safety data for amylase, glucoamylase, alpha-galactosidase, beta-glucanase, hemicellulase, or CereCalase.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, we could not verify interaction data for amylase, glucoamylase, alpha-galactosidase, beta-glucanase, hemicellulase, and CereCalase.
If you take any medications, use the search tool on this page to check your exact drugs before starting.
The bottom line
Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This enzyme blend is a solid choice if you have lactose intolerance or want general digestive support — most of these enzymes are well tolerated. If you're pregnant, breastfeeding, or have a serious digestive condition like inflammatory bowel disease, check with your doctor first.
No medication interactions are documented for the ingredients we could check, but confirm your specific drugs with the tool on this page, and run it by your own pharmacist if you're on multiple medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Zyme Prime Chewable Pomegranate Raspberry, straight from the product label.
| Brand | Houston Enzymes |
|---|---|
| Barcode (UPC) | 898631000007 |
| Net contents | 180 Chewable Tablet(s) |
| Market status | On market |
| Date entered into DSLD | May 23, 2014 |
| DSLD ID | 33829 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Zyme Prime Chewable Pomegranate Raspberry by Houston Enzymes, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 12000 DU | -- |
| Lipase | 500 FIP | -- |
| Lactase | 1500 ALU | -- |
| Glucoamylase | 25 AGU | -- |
| Alpha-Galactosidase | 200 GALU | -- |
| Beta-Glucanase | 0 NP | -- |
| Phytase | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Protease 4.5 | 40000 HUT | -- |
| CereCalase | 400 MU | -- |
Other ingredients: Fructose, Xylitol, natural Pomegranate flavor, Microcrystalline Cellulose, Hydroxypropyl Cellulose, natural Raspberry flavor, Magnesium Stearate, Silica, Citric Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
HIGHEST QUALITY ENZYMES SUPPORT DIGESTION
Zyme Prime Chewable from HOUSTON ENZYMES
Zyme Prime may be helpful for digestion of complex carbohydrates, triglyceride fats, starches and proteins . Contains lactase to aid those intolerant to lactose. Zyme Prime was developed by Dr. Devin Houston, PhD enzyme biochemist.
FRUIT FLAVOR!
Multi-Enzyme Product for Digestion of Carbohydrates, Starches and Fats
Formulation
No added rice, dairy, wheat, gluten, soy, yeast, artificial flavors or colors, or animal derivatives.
VEGETARIAN AND VEGAN FORMULA
Brand IP Statement(s)
CereCalase(R) is a registered trademark of National Enzyme Company.
The AUTHORITY on Enzymes.(TM)
General
ITEM NO. HN002-TF180 REV 09/11
Suggested/Recommended/Usage/Directions
SUGGESTED USE: Two (2) tablets prior to meals. More tablets may be taken as desired. Two (2) chewable tablets are equivalent to one (1) Zyme Prime in capsule form. Tablets may be crushed, using care not to inhale enzyme powder.
Precautions
Do not use if tamper-proof seal is broken.
Storage
Keep container closed and store at room temperature or in freezer, but do not place in refrigerator due to humid conditions.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
HNI
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Zyme Prime Chewable Pomegranate Raspberry by Houston Enzymes label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Zyme Prime Chewable Pomegranate Raspberry by Houston Enzymes
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Amylase
Lipase
No knowninteractions
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...
Lipase monograph & interactionsLactase
No knowninteractions
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...
Lactase monograph & interactionsGlucoamylase
Alpha-Galactosidase
Protease 4.5
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease 4.5 monograph & interactionsCereCalase
- › Beta-Glucanase
- › Phytase
- › Hemicellulase
Other (inactive) ingredients: Fructose, Xylitol, Natural Pomegranate flavor, Microcrystalline Cellulose, Hydroxypropyl Cellulose, Natural Raspberry flavor, Magnesium Stearate, Silica, Citric Acid. These complete the product’s ingredient list but are not active constituents.
Zyme Prime Chewable Pomegranate Raspberry by Houston Enzymes Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Zyme Prime Chewable Pomegranate Raspberry. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Zyme Prime Chewable Pomegranate Raspberry, from the product label.
Houston Enzymes
See all Houston Enzymes products- Name
- Houston Nutraceuticals, Inc. (HNI)
- Street Address
- 116 N. Broadway St.
- City
- Siloam Springs
- State
- AR
- ZipCode
- 72761
- Phone Number
- 866-757-8627
- Web Address
- www.houston-enzymes.com
Zyme Prime Chewable Pomegranate Raspberry by Houston Enzymes: Common Questions
Does Zyme Prime Chewable Pomegranate Raspberry by Houston Enzymes interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is lactase in this product safe if I'm pregnant?
Will this help with lactose intolerance?
Can I use this if I have inflammatory bowel disease?
What are the side effects?
Is this safe to breastfeed while taking?
What does each enzyme do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Zyme Prime Chewable Pomegranate Raspberry is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Zyme Prime Chewable Pomegranate Raspberry’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographPhytase
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...
Read the full Phytase monograph →Sources & How We Checked
Zyme Prime Chewable Pomegranate Raspberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Phytase 7 references
- Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
- Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
- van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
- Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
- Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
- Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
- Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC