Inactive ingredients by manufacturer

Bosentan inactive ingredients by manufacturer

Wondering whether your Bosentan has lactose, gluten, soy, a dye or gelatin in it? The medicine is the same, but the fillers, coatings and colors differ from one company to the next. This page shows what each Bosentan product's FDA label lists, so you can find a version that leaves out what you avoid and ask your pharmacist for it by its NDC.

We have read the FDA labels of 13 of the 14 current Bosentan products on the market today, from 6 companies listing it with the FDA, and lined them up side by side. 1 is still being read and will appear on a later visit.

Ask about your bottle

Is there something in your Bosentan? Ask in plain words.

Name the company, strength or the NDC on your bottle and the ingredient you avoid. The answer comes only from the FDA labels on this page.

Answers are drawn from the FDA label data on this page and checked against it. They are not medical advice: confirm with your pharmacist before relying on them.

The short answer

Which Bosentan products list lactose, a gluten source, soy, dyes or gelatin?

  1. LactoseNo checked product

    No checked Bosentan product lists lactose.

  2. Wheat or gluten sourceNo checked product

    No checked Bosentan product lists a wheat or gluten source.

  3. SoyNo checked product

    No checked Bosentan product lists soy.

  4. Synthetic dyesNo checked product

    No checked Bosentan product lists synthetic dyes.

  5. GelatinNo checked product

    No checked Bosentan product lists gelatin.

Also listed by some products: Corn 11 of 13 Titanium dioxide 9 of 13 Sorbitol or mannitol 2 of 13 Aspartame 4 of 13

Find a version without it

Every current Bosentan product and what its label lists

Hide products that list:

ProductListsInactive ingredients on the label
Actavis Pharma, Inc. 2 products
62.5 mg tabletNDC 00591-2511-60 Corn-derived Titanium dioxide
Show 11 ingredients

ETHYLCELLULOSE (10 MPA.S), FERRIC OXIDE RED, FERRIC OXIDE YELLOW, GLYCERYL BEHENATE/EICOSADIOATE, HYPROMELLOSE 2910 (15 MPA.S), MAGNESIUM STEARATE, POVIDONE K90, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN, TITANIUM DIOXIDE, TRIACETIN
125 mg tabletNDC 00591-2512-60 Corn-derived Titanium dioxide
Show 11 ingredients

ETHYLCELLULOSE (10 MPA.S), FERRIC OXIDE RED, FERRIC OXIDE YELLOW, GLYCERYL BEHENATE/EICOSADIOATE, HYPROMELLOSE 2910 (15 MPA.S), MAGNESIUM STEARATE, POVIDONE K90, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN, TITANIUM DIOXIDE, TRIACETIN
Actelion Pharmaceuticals US, Inc. 3 products
32 mg tabletNDC 66215-0232-56 Aspartame (phenylalanine)
Show 8 ingredients

ACESULFAME POTASSIUM, ANHYDROUS DIBASIC CALCIUM PHOSPHATE, ASPARTAME, CROSCARMELLOSE SODIUM, MAGNESIUM STEARATE, MICROCRYSTALLINE CELLULOSE, SILICON DIOXIDE, TARTARIC ACID
62.5 mg tabletNDC 66215-0101-03 Corn-derived Titanium dioxide
Show 12 ingredients

ETHYLCELLULOSE, UNSPECIFIED, FERRIC OXIDE RED, FERRIC OXIDE YELLOW, GLYCERYL DIBEHENATE, HYPROMELLOSE, UNSPECIFIED, MAGNESIUM STEARATE, POVIDONE K90, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN, TALC, TITANIUM DIOXIDE, TRIACETIN
125 mg tabletNDC 66215-0102-03 Corn-derived Titanium dioxide
Show 12 ingredients

ETHYLCELLULOSE, UNSPECIFIED, FERRIC OXIDE RED, FERRIC OXIDE YELLOW, GLYCERYL DIBEHENATE, HYPROMELLOSE, UNSPECIFIED, MAGNESIUM STEARATE, POVIDONE K90, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN, TALC, TITANIUM DIOXIDE, TRIACETIN
Lupin Pharmaceuticals, Inc. 1 product
32 mg tabletNDC 68180-0340-13 Aspartame (phenylalanine)
Show 7 ingredients

ACESULFAME POTASSIUM, ANHYDROUS DIBASIC CALCIUM PHOSPHATE, ASPARTAME, CROSCARMELLOSE SODIUM, MAGNESIUM STEARATE, MICROCRYSTALLINE CELLULOSE, SILICON DIOXIDE
Sun Pharmaceutical Industries, Inc. 2 products
62.5 mg tabletNDC 47335-0038-64 Corn-derived Titanium dioxide
Show 12 ingredients

ETHYLCELLULOSE, UNSPECIFIED, FERRIC OXIDE RED, FERRIC OXIDE YELLOW, GLYCERYL DIBEHENATE, HYPROMELLOSE, UNSPECIFIED, MAGNESIUM STEARATE, POVIDONE K90, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN, TALC, TITANIUM DIOXIDE, TRIACETIN
125 mg tabletNDC 47335-0039-64 Corn-derived Titanium dioxide
Show 12 ingredients

ETHYLCELLULOSE, UNSPECIFIED, FERRIC OXIDE RED, FERRIC OXIDE YELLOW, GLYCERYL DIBEHENATE, HYPROMELLOSE, UNSPECIFIED, MAGNESIUM STEARATE, POVIDONE K90, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN, TALC, TITANIUM DIOXIDE, TRIACETIN
Zydus Pharmaceuticals USA Inc. 3 products
32 mg tabletNDC 70710-1508-08 Corn-derived Sorbitol or mannitol Aspartame (phenylalanine)
Show 11 ingredients

ACESULFAME POTASSIUM, ASPARTAME, CROSCARMELLOSE SODIUM, DIMETHYLAMINOETHYL METHACRYLATE - BUTYL METHACRYLATE - METHYL METHACRYLATE COPOLYMER, MAGNESIUM STEARATE, MANNITOL, SILICON DIOXIDE, SODIUM LAURYL SULFATE, STARCH, CORN, STEARIC ACID, TALC
62.5 mg tabletNDC 68382-0446-01 Corn-derived Titanium dioxide
Show 12 ingredients

ETHYLCELLULOSES, FERRIC OXIDE RED, FERRIC OXIDE YELLOW, GLYCERYL DIBEHENATE, HYPROMELLOSES, MAGNESIUM STEARATE, POVIDONE, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN, TALC, TITANIUM DIOXIDE, TRIACETIN
125 mg tabletNDC 68382-0447-01 Still being read Not read yet
Zydus Lifesciences Limited 3 products
32 mg tabletNDC 70771-1908-08 Corn-derived Sorbitol or mannitol Aspartame (phenylalanine)
Show 11 ingredients

ACESULFAME POTASSIUM, ASPARTAME, CROSCARMELLOSE SODIUM, DIMETHYLAMINOETHYL METHACRYLATE - BUTYL METHACRYLATE - METHYL METHACRYLATE COPOLYMER, MAGNESIUM STEARATE, MANNITOL, SILICON DIOXIDE, SODIUM LAURYL SULFATE, STARCH, CORN, STEARIC ACID, TALC
62.5 mg tabletNDC 70771-1017-01 Corn-derived Titanium dioxide
Show 12 ingredients

ETHYLCELLULOSE, UNSPECIFIED, FERRIC OXIDE RED, FERRIC OXIDE YELLOW, GLYCERYL DIBEHENATE, HYPROMELLOSE, UNSPECIFIED, MAGNESIUM STEARATE, POVIDONE, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN, TALC, TITANIUM DIOXIDE, TRIACETIN
125 mg tabletNDC 70771-1018-01 Corn-derived Titanium dioxide
Show 12 ingredients

ETHYLCELLULOSE, UNSPECIFIED, FERRIC OXIDE RED, FERRIC OXIDE YELLOW, GLYCERYL DIBEHENATE, HYPROMELLOSE, UNSPECIFIED, MAGNESIUM STEARATE, POVIDONE, SODIUM STARCH GLYCOLATE TYPE A POTATO, STARCH, CORN, TALC, TITANIUM DIOXIDE, TRIACETIN

A product with none of these listed is not certified to be without them: the label says what the manufacturer declared, and the source of a starch or a flavor is often not stated. The companies are the FDA's labelers, which include repackagers and distributors selling another company's product under their own label. The NDC opens the product's own page, with the full label and its inactive-ingredient notes.

Bosentan without corn-derived ingredients

Corn-derived: corn starch, maize or corn syrup; a concern with corn allergy. 11 of 13 checked products list corn-derived ingredients; 2 do not.

Does not list corn-derived ingredients

Lists corn-derived ingredients

Bosentan without titanium dioxide

Titanium dioxide: A white colorant some people choose to avoid. 9 of 13 checked products list titanium dioxide; 4 do not.

Does not list titanium dioxide

Lists titanium dioxide

Bosentan without sorbitol or mannitol

Sorbitol or mannitol: sugar alcohols that can cause bloating or diarrhea in larger amounts. 2 of 13 checked products list sorbitol or mannitol; 11 do not.

Does not list sorbitol or mannitol

Lists sorbitol or mannitol

Bosentan without aspartame (phenylalanine)

Aspartame (phenylalanine): A concern with phenylketonuria (PKU). 4 of 13 checked products list aspartame (phenylalanine); 9 do not.

Does not list aspartame (phenylalanine)

Lists aspartame (phenylalanine)

At the pharmacy counter

How to use this at the pharmacy counter

  1. Pick the company whose list suits you and copy the NDC from the table. Many pharmacies order from wholesalers that carry several companies' versions and can request a particular one if you ask before the prescription is filled; some buy from one contracted source only, and a few insurance plans cover only certain NDCs, so ask the pharmacist to check.
  2. Treat "does not list" as exactly that. The label is what the manufacturer declared; a flavor or a starch may have an unstated source, and lines change. For celiac disease or a serious allergy, ask the manufacturer's medical information line for a written statement about the lot you have.
  3. Check the bottle each refill. A different company usually means a different shape, color and inactive-ingredient list; the pharmacist can tell you who made it, and the two-NDC comparison shows the difference line by line.
  4. If you need one company's version kept constant, ask your prescriber to write that company or the NDC on the prescription and tell the pharmacy you need it held. Rules vary by state and plan, so confirm with the pharmacist.
Ask Dr. Staiger which Bosentan product suits you →

Common questions about Bosentan inactive ingredients

Is Bosentan gluten-free?
This page cannot certify any Bosentan product gluten-free; it reports what each label declares. Of the 13 products checked, none lists a wheat, barley, rye or gluten ingredient, and none lists a starch without a stated source. If you have celiac disease, ask the manufacturer's medical information line for a written gluten statement for the lot you have.
Does Bosentan contain lactose?
No checked Bosentan product lists lactose on its label. The lactose in a tablet or capsule is a small amount, but people with a milk allergy or a strong intolerance often prefer a version that does not list it.
Does Bosentan contain soy?
No checked Bosentan product lists a soy ingredient (soybean oil or soy lecithin) on its label. Soy lecithin is the usual form and the amount is small, but people with a soy allergy often prefer a version that does not list it.
Is there a dye-free Bosentan?
No checked Bosentan product lists a synthetic dye (an FD&C or D&C colorant) on its label. Colorants often differ by strength within one company's line, so compare the lists above strength by strength.
Does Bosentan contain gelatin?
No checked Bosentan product lists gelatin on its label. Gelatin is usually bovine or porcine and the label rarely says which; for kosher, halal or vegetarian needs, ask the manufacturer.
Why do the inactive ingredients differ between manufacturers?
A generic must match the brand's active ingredient, strength, dose form and how it is absorbed; its fillers, binders, coatings and colorants are the manufacturer's own choice. That is why one Bosentan product can list lactose and a dye while another from a different company lists neither.
Can my pharmacy give me a specific manufacturer's version?
Often, if you ask before the prescription is filled: many pharmacies order from wholesalers that carry several companies' versions and can request a particular one. Some pharmacies buy a generic from one contracted source only, and a few insurance plans cover only certain NDCs, so ask the pharmacist to check. Give them the NDC from this page; the company name alone is often enough.
How current is this list?
The products are the ones in the FDA's current NDC directory as of October 5, 2026, and each inactive-ingredient list is the manufacturer's FDA label as our label sync last read it. Formulations change, so check the label on your own bottle and ask your pharmacist if a refill looks different.

Sources: the products are the finished Bosentan products in the FDA's current NDC directory (openFDA), as of October 5, 2026; each inactive-ingredient list is the manufacturer's FDA Structured Product Label via DailyMed, as our label sync last read it. The concern groups are HelloPharmacist's classification of the names the label declares. Educational information only, not medical advice; confirm with your pharmacist before relying on a list. ← Back to the Bosentan guide