Nintedanib
Generic name: Pronounced as (nin ted' a nib )
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 05/15/2020
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
Why is this medication prescribed?
Nintedanib is used to treat idiopathic pulmonary fibrosis (IPF; scarring of the lungs with an unknown cause). It is also used to treat certain types of chronic fibrosing interstitial lung diseases (ILD; an ongoing disease in which there is increased scarring of the lungs). Nintedanib is also used to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD; also known as scleroderma-associated ILD: a disease in which there is scarring of the lungs that is often fatal). Nintedanib is in a class of medications called kinase inhibitors. It works by blocking the action of enzymes involved in causing fibrosis.
How should this medicine be used?
Nintedanib comes as a capsule to take by mouth. It is usually taken with food every 12 hours (twice a day). Take nintedanib capsules at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nintedanib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the capsules whole with liquid; do not chew or crush them.
Your doctor may need to decrease your dose or stop treatment if you experience certain severe side effects. Be sure to tell your doctor how you are feeling during your treatment.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking nintedanib,
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tell your doctor and pharmacist if you are allergic to nintedanib, any other medications, or any of the ingredients in nintedanib capsules. Ask your pharmacist or check the manufacturer's patient information for a list of the ingredients.
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tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants (''blood thinners'') such as warfarin (Coumadin, Jantoven); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Anaprox, Naprelan); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); erythromycin (E.E.S., Ery-Tab, Eryc); ketoconazole; laxatives; oral steroids such as dexamethasone (Decadron, Dexpak), methylprednisolone (Medrol), and prednisone; phenytoin (Dilantin, Phenytek); pirfenidone (Esbriet); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); or stool softeners. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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tell your doctor what herbal products you are taking, especially St. John's wort.
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tell your doctor if you or anyone in your family has ever had a bleeding problem, if you have or have ever had liver or heart disease, diverticular disease (diverticulitis; small pouches in the lining of the large intestine that can become inflamed), or blood clots, and if you have had recent abdominal surgery.
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tell your doctor if you are pregnant, plan to become pregnant, or can possibly become pregnant. You should not start taking nintedanib until a pregnancy test has shown that you are not pregnant. You should not become pregnant while you are taking nintedanib; the medication may harm your unborn baby. Nintedanib may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, implants, or injections), so you should not use these as your only method of birth control. You must also use a barrier method of birth control (device that blocks sperm from entering the uterus such as a condom or a diaphragm). Talk to your doctor about birth control methods that you can use during your treatment and for at least 3 months after your last dose of nintedanib. If you become pregnant while taking nintedanib, call your doctor immediately.
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tell your doctor if you are breastfeeding.
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tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this medication. You should stop smoking before you start taking nintedanib and avoid smoking during your treatment.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
If you miss a dose of nintedanib, skip the missed dose and continue your regular schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Nintedanib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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nausea
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vomiting
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decreased appetite
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weight loss
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Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
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diarrhea
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extreme tiredness
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unusual bleeding or bruising
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lack of energy
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loss of appetite
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pain in the upper right part of the stomach
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yellowing of the skin or eyes
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dark or brown (tea-colored) urine
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chest pain
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pain in your arms, back, neck, or jaw
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shortness of breath
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numbness or weakness on one side of your body
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difficulty speaking
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headache
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dizziness
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wounds that do not heal
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pain or swelling in your stomach area, nausea, vomiting, fever, chills, or blood in your stool
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rash
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itching
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Nintedanib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests before and during your treatment to check your body's response to nintedanib.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Delavirdine | Delavirdine The metabolism of Nintedanib can be decreased when combined with Delavirdine. |
Aminophylline | Aminophylline The metabolism of Aminophylline can be decreased when combined with Nintedanib. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The serum concentration of Nintedanib can be increased when it is combined with Erythromycin. |
Fenofibrate | Fenofibrate The metabolism of Nintedanib can be decreased when combined with Fenofibrate. |
Methylergonovine | Methylergonovine The metabolism of Nintedanib can be decreased when combined with Methylergometrine. |
Paregoric | Paregoric The serum concentration of Nintedanib can be increased when it is combined with Morphine. |
Reserpine | Reserpine The serum concentration of Nintedanib can be increased when it is combined with Reserpine. |
Tacrolimus | Tacrolimus The metabolism of Tacrolimus can be decreased when combined with Nintedanib. |
Triamcinolone | Triamcinolone The metabolism of Nintedanib can be increased when combined with Triamcinolone. |
Doxycycline Injection | Doxycycline Injection The metabolism of Nintedanib can be decreased when combined with Doxycycline. |
Fluconazole Injection | Fluconazole Injection The serum concentration of Nintedanib can be increased when it is combined with Fluconazole. |
Meperidine Injection | Meperidine Injection The metabolism of Nintedanib can be increased when combined with Meperidine. |
Methylprednisolone Injection | Methylprednisolone Injection The metabolism of Nintedanib can be increased when combined with Methylprednisolone. |
Metronidazole Injection | Metronidazole Injection The metabolism of Nintedanib can be decreased when combined with Metronidazole. |
Morphine Injection | Morphine Injection The serum concentration of Nintedanib can be increased when it is combined with Morphine. |
Zidovudine Injection | Zidovudine Injection The metabolism of Nintedanib can be increased when combined with Zidovudine. |
Cyclosporine | Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Nintedanib. |
Enoxaparin Injection | Enoxaparin Injection The risk or severity of bleeding can be increased when Enoxaparin is combined with Nintedanib. |
Dofetilide | Dofetilide The metabolism of Dofetilide can be decreased when combined with Nintedanib. |
Orlistat | Orlistat The metabolism of Nintedanib can be increased when combined with Orlistat. |
Oxcarbazepine | Oxcarbazepine The metabolism of Nintedanib can be increased when combined with Oxcarbazepine. |
Anakinra | Anakinra The metabolism of Nintedanib can be increased when combined with Anakinra. |
Pentosan Polysulfate | Pentosan Polysulfate The risk or severity of bleeding can be increased when Pentosan polysulfate is combined with Nintedanib. |
Trimipramine | Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Nintedanib. |
Etanercept Injection | Etanercept Injection The metabolism of Nintedanib can be increased when combined with Etanercept. |
Modafinil | Modafinil The metabolism of Nintedanib can be increased when combined with Modafinil. |
Tenofovir | Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Nintedanib. |
Sirolimus | Sirolimus The metabolism of Sirolimus can be decreased when combined with Nintedanib. |
Epinephrine Injection | Epinephrine Injection The metabolism of Nintedanib can be decreased when combined with Epinephrine. |
Zonisamide | Zonisamide The serum concentration of Nintedanib can be increased when it is combined with Zonisamide. |
Adalimumab Injection | Adalimumab Injection The metabolism of Nintedanib can be increased when combined with Adalimumab. |
Teriparatide Injection | Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Nintedanib. |
Atazanavir | Atazanavir The metabolism of Nintedanib can be decreased when combined with Atazanavir. |
Mefloquine | Mefloquine The metabolism of Nintedanib can be decreased when combined with Mefloquine. |
Rosuvastatin | Rosuvastatin The metabolism of Nintedanib can be decreased when combined with Rosuvastatin. |
Vardenafil | Vardenafil The serum concentration of Nintedanib can be increased when it is combined with Vardenafil. |
Aprepitant | Aprepitant The metabolism of Nintedanib can be decreased when combined with Aprepitant. |
Tegaserod | Tegaserod The serum concentration of Nintedanib can be increased when it is combined with Tegaserod. |
Progesterone | Progesterone The metabolism of Nintedanib can be increased when combined with Progesterone. |
Darbepoetin Alfa Injection | Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Nintedanib. |
Infliximab Injection | Infliximab Injection The metabolism of Nintedanib can be increased when combined with Infliximab. |
Rifaximin | Rifaximin The metabolism of Nintedanib can be increased when combined with Rifaximin. |
Duloxetine | Duloxetine The metabolism of Nintedanib can be decreased when combined with Duloxetine. |
Norethindrone | Norethindrone The metabolism of Nintedanib can be decreased when combined with Norethisterone. |
Bosentan | Bosentan The metabolism of Nintedanib can be increased when combined with Bosentan. |
Erlotinib | Erlotinib The metabolism of Nintedanib can be decreased when combined with Erlotinib. |
Voriconazole | Voriconazole The metabolism of Nintedanib can be decreased when combined with Voriconazole. |
Deferasirox | Deferasirox The metabolism of Nintedanib can be increased when combined with Deferasirox. |
Tipranavir | Tipranavir The metabolism of Tipranavir can be decreased when combined with Nintedanib. |
Felbamate | Felbamate The metabolism of Nintedanib can be increased when combined with Felbamate. |
Ranolazine | Ranolazine The serum concentration of Nintedanib can be increased when it is combined with Ranolazine. |
Abatacept Injection | Abatacept Injection The metabolism of Nintedanib can be increased when combined with Abatacept. |
Imatinib | Imatinib The metabolism of Nintedanib can be decreased when combined with Imatinib. |
Sitagliptin | Sitagliptin The serum concentration of Nintedanib can be increased when it is combined with Sitagliptin. |
Gefitinib | Gefitinib The metabolism of Nintedanib can be decreased when combined with Gefitinib. |
Paliperidone | Paliperidone The serum concentration of Nintedanib can be increased when it is combined with Paliperidone. |
Bortezomib | Bortezomib The metabolism of Bortezomib can be decreased when combined with Nintedanib. |
Posaconazole | Posaconazole The metabolism of Nintedanib can be decreased when combined with Posaconazole. |
Primaquine | Primaquine The metabolism of Nintedanib can be decreased when combined with Primaquine. |
Darunavir | Darunavir The metabolism of Darunavir can be decreased when combined with Nintedanib. |
Sorafenib | Sorafenib The metabolism of Nintedanib can be decreased when combined with Sorafenib. |
Sunitinib | Sunitinib The metabolism of Nintedanib can be decreased when combined with Sunitinib. |
Lapatinib | Lapatinib The serum concentration of Nintedanib can be increased when it is combined with Lapatinib. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be decreased when combined with Nintedanib. |
Armodafinil | Armodafinil The metabolism of Nintedanib can be increased when combined with Armodafinil. |
Ivermectin | Ivermectin The metabolism of Nintedanib can be increased when combined with Ivermectin. |
Temsirolimus | Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Nintedanib. |
Nilotinib | Nilotinib The metabolism of Nintedanib can be decreased when combined with Nilotinib. |
Toremifene | Toremifene The serum concentration of Nintedanib can be increased when it is combined with Toremifene. |
Bexarotene | Bexarotene The metabolism of Nintedanib can be increased when combined with Bexarotene. |
Budesonide | Budesonide The metabolism of Nintedanib can be increased when combined with Budesonide. |
Chloramphenicol Injection | Chloramphenicol Injection The metabolism of Nintedanib can be decreased when combined with Chloramphenicol. |
Etravirine | Etravirine The metabolism of Nintedanib can be increased when combined with Etravirine. |
Mitoxantrone Injection | Mitoxantrone Injection The metabolism of Nintedanib can be decreased when combined with Mitoxantrone. |
Desvenlafaxine | Desvenlafaxine The metabolism of Nintedanib can be decreased when combined with Desvenlafaxine. |
Bendamustine Injection | Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Nintedanib. |
Pilocarpine | Pilocarpine The metabolism of Nintedanib can be decreased when combined with Pilocarpine. |
Certolizumab Injection | Certolizumab Injection The metabolism of Nintedanib can be increased when combined with Certolizumab pegol. |
Ixabepilone Injection | Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Nintedanib. |
Irinotecan Injection | Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Nintedanib. |
Mitotane | Mitotane The metabolism of Nintedanib can be increased when combined with Mitotane. |
Rufinamide | Rufinamide The metabolism of Nintedanib can be increased when combined with Rufinamide. |
Silodosin | Silodosin The serum concentration of Nintedanib can be increased when it is combined with Silodosin. |
Midazolam | Midazolam The metabolism of Nintedanib can be decreased when combined with Midazolam. |
Eltrombopag | Eltrombopag The metabolism of Nintedanib can be decreased when combined with Eltrombopag. |
Milnacipran | Milnacipran The metabolism of Nintedanib can be decreased when combined with Milnacipran. |
Prasugrel | Prasugrel The risk or severity of bleeding can be increased when Prasugrel is combined with Nintedanib. |
Lacosamide | Lacosamide The metabolism of Nintedanib can be decreased when combined with Lacosamide. |
Everolimus | Everolimus The metabolism of Everolimus can be decreased when combined with Nintedanib. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The metabolism of Nintedanib can be decreased when combined with Tolvaptan. |
Dronedarone | Dronedarone The metabolism of Dronedarone can be decreased when combined with Nintedanib. |
Romidepsin Injection | Romidepsin Injection The metabolism of Nintedanib can be decreased when combined with Romidepsin. |
Topotecan | Topotecan The metabolism of Nintedanib can be decreased when combined with Topotecan. |
Golimumab Injection | Golimumab Injection The metabolism of Nintedanib can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The metabolism of Nintedanib can be decreased when combined with Pazopanib. |
Albendazole | Albendazole The metabolism of Nintedanib can be decreased when combined with Albendazole. |
Dabigatran | Dabigatran The risk or severity of bleeding can be increased when Dabigatran is combined with Nintedanib. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Nintedanib can be increased when combined with Tocilizumab. |
Cabazitaxel Injection | Cabazitaxel Injection The metabolism of Nintedanib can be decreased when combined with Cabazitaxel. |
Acetaminophen Injection | Acetaminophen Injection The serum concentration of Acetaminophen can be increased when it is combined with Nintedanib. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection The metabolism of Nintedanib can be decreased when combined with Aldesleukin. |
Busulfan Injection | Busulfan Injection The metabolism of Busulfan can be decreased when combined with Nintedanib. |
Roflumilast | Roflumilast The metabolism of Nintedanib can be decreased when combined with Roflumilast. |
Linagliptin | Linagliptin The serum concentration of Nintedanib can be increased when it is combined with Linagliptin. |
Rilpivirine | Rilpivirine The metabolism of Nintedanib can be decreased when combined with Rilpivirine. |
Telaprevir | Telaprevir The serum concentration of Nintedanib can be increased when it is combined with Glecaprevir. |
Potassium Iodide | Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Nintedanib. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Nintedanib can be decreased when combined with Cyclophosphamide. |
Rivaroxaban | Rivaroxaban The risk or severity of bleeding can be increased when Rivaroxaban is combined with Nintedanib. |
Ticagrelor | Ticagrelor The risk or severity of bleeding can be increased when Ticagrelor is combined with Nintedanib. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The metabolism of Nintedanib can be decreased when combined with Brentuximab vedotin. |
Ruxolitinib | Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Nintedanib. |
Vandetanib | Vandetanib The metabolism of Nintedanib can be decreased when combined with Vandetanib. |
Clobazam | Clobazam The serum concentration of Nintedanib can be increased when it is combined with Clobazam. |
Vemurafenib | Vemurafenib The serum concentration of Nintedanib can be increased when it is combined with Vemurafenib. |
Ivacaftor | Ivacaftor The serum concentration of Nintedanib can be increased when it is combined with Ivacaftor. |
Axitinib | Axitinib The metabolism of Axitinib can be decreased when combined with Nintedanib. |
Crizotinib | Crizotinib The metabolism of Nintedanib can be decreased when combined with Crizotinib. |
Cabergoline | Cabergoline The metabolism of Nintedanib can be decreased when combined with Cabergoline. |
Naloxone Injection | Naloxone Injection The metabolism of Nintedanib can be decreased when combined with Naloxone. |
Ambrisentan | Ambrisentan The serum concentration of Nintedanib can be increased when it is combined with Ambrisentan. |
Fondaparinux Injection | Fondaparinux Injection The risk or severity of bleeding can be increased when Fondaparinux is combined with Nintedanib. |
Carfilzomib Injection | Carfilzomib Injection The serum concentration of Nintedanib can be increased when it is combined with Carfilzomib. |
Iloprost | Iloprost The risk or severity of bleeding can be increased when Iloprost is combined with Nintedanib. |
Enzalutamide | Enzalutamide The metabolism of Nintedanib can be increased when combined with Enzalutamide. |
Mirabegron | Mirabegron The serum concentration of Nintedanib can be increased when it is combined with Mirabegron. |
Regorafenib | Regorafenib The metabolism of Nintedanib can be decreased when combined with Regorafenib. |
Bosutinib | Bosutinib The metabolism of Nintedanib can be decreased when combined with Bosutinib. |
Corticotropin, Repository Injection | Corticotropin, Repository Injection The metabolism of Nintedanib can be increased when combined with Corticotropin. |
Ponatinib | Ponatinib The metabolism of Nintedanib can be decreased when combined with Ponatinib. |
Pomalidomide | Pomalidomide The metabolism of Nintedanib can be decreased when combined with Pomalidomide. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The metabolism of Nintedanib can be decreased when combined with Trastuzumab emtansine. |
Apixaban | Apixaban The risk or severity of bleeding can be increased when Apixaban is combined with Nintedanib. |
Canagliflozin | Canagliflozin The serum concentration of Nintedanib can be increased when it is combined with Canagliflozin. |
Dabrafenib | Dabrafenib The metabolism of Nintedanib can be decreased when combined with Dabrafenib. |
Trametinib | Trametinib The metabolism of Nintedanib can be increased when combined with Trametinib. |
Dolutegravir | Dolutegravir The serum concentration of Nintedanib can be increased when it is combined with Dolutegravir. |
Afatinib | Afatinib The serum concentration of Nintedanib can be increased when it is combined with Afatinib. |
Perampanel | Perampanel The metabolism of Nintedanib can be increased when combined with Perampanel. |
Lomitapide | Lomitapide The metabolism of Nintedanib can be decreased when combined with Lomitapide. |
Simeprevir | Simeprevir The serum concentration of Nintedanib can be increased when it is combined with Simeprevir. |
Sofosbuvir | Sofosbuvir The serum concentration of Nintedanib can be increased when it is combined with Sofosbuvir. |
Apremilast | Apremilast The metabolism of Nintedanib can be increased when combined with Apremilast. |
Ceritinib | Ceritinib The metabolism of Nintedanib can be decreased when combined with Ceritinib. |
Siltuximab Injection | Siltuximab Injection The metabolism of Nintedanib can be increased when combined with Siltuximab. |
Eslicarbazepine | Eslicarbazepine The metabolism of Nintedanib can be increased when combined with Eslicarbazepine. |
Belinostat Injection | Belinostat Injection The serum concentration of Nintedanib can be increased when it is combined with Belinostat. |
Idelalisib | Idelalisib The metabolism of Idelalisib can be decreased when combined with Nintedanib. |
Testosterone Injection | Testosterone Injection The metabolism of Nintedanib can be increased when combined with Testosterone. |
Oritavancin Injection | Oritavancin Injection The metabolism of Nintedanib can be increased when combined with Oritavancin. |
Vorapaxar | Vorapaxar The risk or severity of bleeding can be increased when Vorapaxar is combined with Nintedanib. |
Suvorexant | Suvorexant The serum concentration of Nintedanib can be increased when it is combined with Suvorexant. |
Edoxaban | Edoxaban The risk or severity of bleeding can be increased when Edoxaban is combined with Nintedanib. |
Olaparib | Olaparib The metabolism of Nintedanib can be decreased when combined with Olaparib. |
Tasimelteon | Tasimelteon The metabolism of Nintedanib can be decreased when combined with Tasimelteon. |
Lanreotide Injection | Lanreotide Injection The metabolism of Nintedanib can be decreased when combined with Lanreotide. |
Pirfenidone | Pirfenidone The risk or severity of adverse effects can be increased when Pirfenidone is combined with Nintedanib. |
Secukinumab Injection | Secukinumab Injection The metabolism of Nintedanib can be increased when combined with Secukinumab. |
Palbociclib | Palbociclib The metabolism of Nintedanib can be decreased when combined with Palbociclib. |
Lenvatinib | Lenvatinib The serum concentration of Nintedanib can be increased when it is combined with Lenvatinib. |
Panobinostat | Panobinostat The metabolism of Nintedanib can be decreased when combined with Panobinostat. |
Haloperidol Injection | Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Nintedanib. |
Isavuconazonium Injection | Isavuconazonium Injection The serum concentration of Nintedanib can be increased when it is combined with Isavuconazonium. |
Sonidegib | Sonidegib The metabolism of Sonidegib can be decreased when combined with Nintedanib. |
Flibanserin | Flibanserin The serum concentration of Nintedanib can be increased when it is combined with Flibanserin. |
Rolapitant | Rolapitant The serum concentration of Nintedanib can be increased when it is combined with Rolapitant. |
Prednisolone | Prednisolone The metabolism of Nintedanib can be increased when combined with Prednisolone. |
Daclatasvir | Daclatasvir The serum concentration of Nintedanib can be increased when it is combined with Daclatasvir. |
Ziprasidone Injection | Ziprasidone Injection The metabolism of Nintedanib can be decreased when combined with Ziprasidone. |
Cobimetinib | Cobimetinib The metabolism of Nintedanib can be decreased when combined with Cobimetinib. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Nintedanib. |
Osimertinib | Osimertinib The metabolism of Osimertinib can be decreased when combined with Nintedanib. |
Alectinib | Alectinib The metabolism of Alectinib can be decreased when combined with Nintedanib. |
Ixazomib | Ixazomib The metabolism of Ixazomib can be decreased when combined with Nintedanib. |
Rifapentine | Rifapentine The metabolism of Nintedanib can be increased when combined with Rifapentine. |
Lesinurad | Lesinurad The metabolism of Nintedanib can be increased when combined with Lesinurad. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection The metabolism of Nintedanib can be decreased when combined with Amphotericin B. |
Dexamethasone Injection | Dexamethasone Injection The metabolism of Nintedanib can be increased when combined with Dexamethasone. |
Defibrotide Injection | Defibrotide Injection The risk or severity of bleeding can be increased when Defibrotide is combined with Nintedanib. |
Venetoclax | Venetoclax The metabolism of Nintedanib can be decreased when combined with Venetoclax. |
Cobicistat | Cobicistat The metabolism of Nintedanib can be decreased when combined with Cobicistat. |
Selexipag | Selexipag The serum concentration of Selexipag can be increased when it is combined with Nintedanib. |
Rucaparib | Rucaparib The serum concentration of Nintedanib can be increased when it is combined with Rucaparib. |
Ribociclib | Ribociclib The metabolism of Nintedanib can be decreased when combined with Ribociclib. |
Parathyroid Hormone Injection | Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Nintedanib. |
Brigatinib | Brigatinib The metabolism of Nintedanib can be decreased when combined with Brigatinib. |
Deflazacort | Deflazacort The metabolism of Nintedanib can be increased when combined with Deflazacort. |
Sarilumab Injection | Sarilumab Injection The metabolism of Nintedanib can be increased when combined with Sarilumab. |
Midostaurin | Midostaurin The metabolism of Nintedanib can be increased when combined with Midostaurin. |
Neratinib | Neratinib The metabolism of Nintedanib can be decreased when combined with Neratinib. |
Abaloparatide Injection | Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Nintedanib. |
Enasidenib | Enasidenib The metabolism of Nintedanib can be decreased when combined with Enasidenib. |
Inotuzumab Ozogamicin Injection | Inotuzumab Ozogamicin Injection The serum concentration of Nintedanib can be increased when it is combined with Inotuzumab ozogamicin. |
Aprepitant/Fosaprepitant Injection | Aprepitant/Fosaprepitant Injection The metabolism of Nintedanib can be increased when combined with Fosaprepitant. |
Copanlisib Injection | Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Nintedanib. |
Abemaciclib | Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Nintedanib. |
Betrixaban | Betrixaban The risk or severity of bleeding can be increased when Betrixaban is combined with Nintedanib. |
Acalabrutinib | Acalabrutinib The metabolism of Nintedanib can be decreased when combined with Acalabrutinib. |
Letermovir | Letermovir The metabolism of Nintedanib can be decreased when combined with Letermovir. |
Ertugliflozin | Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Nintedanib. |
Buprenorphine Injection | Buprenorphine Injection The metabolism of Nintedanib can be decreased when combined with Buprenorphine. |
Apalutamide | Apalutamide The serum concentration of Nintedanib can be decreased when it is combined with Apalutamide. |
Fostamatinib | Fostamatinib The metabolism of Nintedanib can be decreased when combined with Fostamatinib. |
Avatrombopag | Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Nintedanib. |
Baricitinib | Baricitinib The metabolism of Baricitinib can be decreased when combined with Nintedanib. |
Eliglustat | Eliglustat The serum concentration of Nintedanib can be increased when it is combined with Eliglustat. |
Binimetinib | Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Nintedanib. |
Ivosidenib | Ivosidenib The metabolism of Nintedanib can be decreased when combined with Ivosidenib. |
Lusutrombopag | Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Nintedanib. |
Elagolix | Elagolix The serum concentration of Elagolix can be increased when it is combined with Nintedanib. |
Dacomitinib | Dacomitinib The metabolism of Nintedanib can be decreased when combined with Dacomitinib. |
Duvelisib | Duvelisib The serum concentration of Duvelisib can be increased when it is combined with Nintedanib. |
Omadacycline | Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Nintedanib. |
Sarecycline | Sarecycline The serum concentration of Nintedanib can be increased when it is combined with Sarecycline. |
Stiripentol | Stiripentol The metabolism of Nintedanib can be decreased when combined with Stiripentol. |
Talazoparib | Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Nintedanib. |
Gilteritinib | Gilteritinib The serum concentration of Gilteritinib can be increased when it is combined with Nintedanib. |
Glasdegib | Glasdegib The serum concentration of Nintedanib can be increased when it is combined with Glasdegib. |
Larotrectinib | Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Nintedanib. |
Methoxy Polyethylene Glycol-Epoetin Beta Injection | Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Nintedanib. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Nintedanib. |
Rifamycin | Rifamycin The metabolism of Nintedanib can be increased when combined with Rifamycin. |
Prucalopride | Prucalopride The metabolism of Nintedanib can be decreased when combined with Prucalopride. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Nintedanib can be increased when combined with Emapalumab. |
Siponimod | Siponimod The metabolism of Siponimod can be decreased when combined with Nintedanib. |
Erdafitinib | Erdafitinib The serum concentration of Nintedanib can be increased when it is combined with Erdafitinib. |
Alpelisib | Alpelisib The metabolism of Nintedanib can be decreased when combined with Alpelisib. |
Darolutamide | Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Nintedanib. |
Triclabendazole | Triclabendazole The metabolism of Nintedanib can be decreased when combined with Triclabendazole. |
Entrectinib | Entrectinib The metabolism of Nintedanib can be decreased when combined with Entrectinib. |
Pexidartinib | Pexidartinib The metabolism of Nintedanib can be decreased when combined with Pexidartinib. |
Istradefylline | Istradefylline The serum concentration of Nintedanib can be increased when it is combined with Istradefylline. |
Pitolisant | Pitolisant The serum concentration of Nintedanib can be decreased when it is combined with Pitolisant. |
Fedratinib | Fedratinib The serum concentration of Nintedanib can be increased when it is combined with Fedratinib. |
Lefamulin | Lefamulin The metabolism of Lefamulin can be decreased when combined with Nintedanib. |
Phenytoin Injection | Phenytoin Injection The metabolism of Nintedanib can be increased when combined with Phenytoin. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Nintedanib can be increased when combined with Fosphenytoin. |
Enfortumab vedotin-ejfv Injection | Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Nintedanib. |
Zanubrutinib | Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Nintedanib. |
Lasmiditan | Lasmiditan The serum concentration of Nintedanib can be increased when it is combined with Lasmiditan. |
Ubrogepant | Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Nintedanib. |
Tazemetostat | Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Nintedanib. |
Cenobamate | Cenobamate The serum concentration of Nintedanib can be decreased when it is combined with Cenobamate. |
Selumetinib | Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Nintedanib. |
Rimegepant | Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Nintedanib. |
Tucatinib | Tucatinib Nintedanib may decrease the excretion rate of Tucatinib which could result in a higher serum level. |
Remdesivir Injection | Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Nintedanib. |
Ripretinib | Ripretinib The serum concentration of Nintedanib can be increased when it is combined with Ripretinib. |
Lemborexant | Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Nintedanib. |
Fostemsavir | Fostemsavir The serum concentration of Fostemsavir can be increased when it is combined with Nintedanib. |
Octreotide | Octreotide The metabolism of Nintedanib can be decreased when combined with Octreotide. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Nintedanib. |
Pralsetinib | Pralsetinib The serum concentration of Nintedanib can be increased when it is combined with Pralsetinib. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Nintedanib can be decreased when it is combined with Satralizumab. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Nintedanib can be decreased when combined with Drospirenone. |
Vitamin E (Alpha-Tocopherol) | Vitamin E (Alpha-Tocopherol) The metabolism of Nintedanib can be increased when combined with Vitamin E. |
Theophylline | Theophylline The metabolism of Theophylline can be decreased when combined with Nintedanib. |
Indomethacin | Indomethacin The metabolism of Nintedanib can be decreased when combined with Indomethacin. |
Phenobarbital | Phenobarbital The metabolism of Nintedanib can be increased when combined with Phenobarbital. |
Methotrexate Injection | Methotrexate Injection The metabolism of Methotrexate can be decreased when combined with Nintedanib. |
Primidone | Primidone The metabolism of Nintedanib can be increased when combined with Primidone. |
Chlorpromazine | Chlorpromazine The metabolism of Nintedanib can be increased when combined with Chlorpromazine. |
Diazepam | Diazepam The metabolism of Nintedanib can be decreased when combined with Diazepam. |
Lorazepam | Lorazepam The metabolism of Nintedanib can be decreased when combined with Lorazepam. |
Bromocriptine | Bromocriptine The metabolism of Nintedanib can be decreased when combined with Bromocriptine. |
Tranylcypromine | Tranylcypromine The metabolism of Nintedanib can be decreased when combined with Tranylcypromine. |
Phenelzine | Phenelzine The metabolism of Nintedanib can be decreased when combined with Phenelzine. |
Tetracycline | Tetracycline The metabolism of Nintedanib can be decreased when combined with Tetracycline. |
Prochlorperazine | Prochlorperazine The metabolism of Nintedanib can be decreased when combined with Prochlorperazine. |
Methadone | Methadone The metabolism of Nintedanib can be increased when combined with Methadone. |
Oxybutynin | Oxybutynin The metabolism of Nintedanib can be decreased when combined with Oxybutynin. |
Orphenadrine | Orphenadrine The metabolism of Nintedanib can be decreased when combined with Orphenadrine. |
Phentermine | Phentermine The metabolism of Nintedanib can be decreased when combined with Phentermine. |
Hydrocortisone | Hydrocortisone The metabolism of Nintedanib can be increased when combined with Hydrocortisone. |
Doxorubicin | Doxorubicin The metabolism of Nintedanib can be decreased when combined with Doxorubicin. |
Dactinomycin | Dactinomycin The serum concentration of Nintedanib can be increased when it is combined with Dactinomycin. |
Carbamazepine | Carbamazepine The metabolism of Carbamazepine can be increased when combined with Nintedanib. |
Clonidine | Clonidine The metabolism of Clonidine can be decreased when combined with Nintedanib. |
Hydralazine | Hydralazine The metabolism of Nintedanib can be decreased when combined with Hydralazine. |
Cimetidine | Cimetidine The metabolism of Nintedanib can be decreased when combined with Cimetidine. |
Warfarin | Warfarin The risk or severity of bleeding can be increased when Warfarin is combined with Nintedanib. |
Loperamide | Loperamide The metabolism of Nintedanib can be decreased when combined with Loperamide. |
Daunorubicin | Daunorubicin The metabolism of Nintedanib can be decreased when combined with Daunorubicin. |
Griseofulvin | Griseofulvin The metabolism of Nintedanib can be increased when combined with Griseofulvin. |
Digoxin | Digoxin The serum concentration of Digoxin can be increased when it is combined with Nintedanib. |
Loxapine | Loxapine The serum concentration of Nintedanib can be increased when it is combined with Loxapine. |
Quinine | Quinine The serum concentration of Nintedanib can be increased when it is combined with Quinine. |
Calcitriol | Calcitriol The metabolism of Nintedanib can be increased when combined with Calcitriol. |
Sulfinpyrazone | Sulfinpyrazone The metabolism of Nintedanib can be increased when combined with Sulfinpyrazone. |
Secobarbital | Secobarbital The metabolism of Nintedanib can be increased when combined with Secobarbital. |
Desipramine | Desipramine The metabolism of Nintedanib can be decreased when combined with Desipramine. |
Amitriptyline | Amitriptyline The metabolism of Nintedanib can be decreased when combined with Amitriptyline. |
Imipramine | Imipramine The serum concentration of Imipramine can be increased when it is combined with Nintedanib. |
Probenecid | Probenecid The metabolism of Nintedanib can be increased when combined with Probenecid. |
Quinidine | Quinidine The metabolism of Quinidine can be decreased when combined with Nintedanib. |
Isoniazid | Isoniazid The metabolism of Nintedanib can be decreased when combined with Isoniazid. |
Rifampin | Rifampin The serum concentration of Rifampicin can be decreased when it is combined with Nintedanib. |
Valproic Acid | Valproic Acid The metabolism of Nintedanib can be decreased when combined with Valproic acid. |
Tamoxifen | Tamoxifen The metabolism of Nintedanib can be decreased when combined with Tamoxifen. |
Levothyroxine | Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Nintedanib. |
Liothyronine | Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Nintedanib. |
Methimazole | Methimazole The therapeutic efficacy of Methimazole can be decreased when used in combination with Nintedanib. |
Propylthiouracil | Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Nintedanib. |
Niacin | Niacin The metabolism of Nintedanib can be decreased when combined with Niacin. |
Danazol | Danazol The metabolism of Nintedanib can be decreased when combined with Danazol. |
Nortriptyline | Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Nintedanib. |
Amphotericin B Injection | Amphotericin B Injection The metabolism of Nintedanib can be decreased when combined with Amphotericin B. |
Clomiphene | Clomiphene The serum concentration of Nintedanib can be increased when it is combined with Clomifene. |
Colchicine | Colchicine The metabolism of Nintedanib can be increased when combined with Colchicine. |
Cephalexin | Cephalexin The metabolism of Nintedanib can be decreased when combined with Cephalexin. |
Acetazolamide | Acetazolamide The metabolism of Nintedanib can be decreased when combined with Acetazolamide. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Nintedanib. |
Ketoconazole | Ketoconazole The serum concentration of Nintedanib can be increased when it is combined with Ketoconazole. |
Thiotepa Injection | Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Nintedanib. |
Vincristine Injection | Vincristine Injection The metabolism of Vincristine can be decreased when combined with Nintedanib. |
Dipyridamole | Dipyridamole The risk or severity of bleeding can be increased when Dipyridamole is combined with Nintedanib. |
Vinblastine | Vinblastine The metabolism of Nintedanib can be decreased when combined with Vinblastine. |
Metoprolol | Metoprolol The metabolism of Nintedanib can be decreased when combined with Metoprolol. |
Aspirin | Aspirin The risk or severity of bleeding can be increased when Acetylsalicylic acid is combined with Nintedanib. |
Diltiazem | Diltiazem The metabolism of Nintedanib can be decreased when combined with Diltiazem. |
Nifedipine | Nifedipine The metabolism of Nintedanib can be increased when combined with Nifedipine. |
Verapamil | Verapamil The serum concentration of Nintedanib can be increased when it is combined with Verapamil. |
Etoposide | Etoposide The metabolism of Nintedanib can be decreased when combined with Etoposide. |
Glyburide | Glyburide The metabolism of Nintedanib can be decreased when combined with Glyburide. |
Dicloxacillin | Dicloxacillin The metabolism of Nintedanib can be increased when combined with Dicloxacillin. |
Nafcillin Injection | Nafcillin Injection The metabolism of Nintedanib can be increased when combined with Nafcillin. |
Gemfibrozil | Gemfibrozil The metabolism of Nintedanib can be decreased when combined with Gemfibrozil. |
Pimozide | Pimozide The metabolism of Pimozide can be decreased when combined with Nintedanib. |
Flurbiprofen | Flurbiprofen The metabolism of Nintedanib can be decreased when combined with Flurbiprofen. |
Amiodarone | Amiodarone The metabolism of Amiodarone can be decreased when combined with Nintedanib. |
Lovastatin | Lovastatin The metabolism of Nintedanib can be decreased when combined with Lovastatin. |
Ciprofloxacin | Ciprofloxacin The metabolism of Nintedanib can be decreased when combined with Ciprofloxacin. |
Clozapine | Clozapine The metabolism of Nintedanib can be decreased when combined with Clozapine. |
Clarithromycin | Clarithromycin The metabolism of Nintedanib can be decreased when combined with Clarithromycin. |
Felodipine | Felodipine The metabolism of Nintedanib can be decreased when combined with Felodipine. |
Pravastatin | Pravastatin The serum concentration of Nintedanib can be increased when it is combined with Pravastatin. |
Simvastatin | Simvastatin The serum concentration of Nintedanib can be increased when it is combined with Simvastatin. |
Epoetin Alfa, Injection | Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Nintedanib. |
Teniposide Injection | Teniposide Injection The metabolism of Nintedanib can be decreased when combined with Teniposide. |
Itraconazole | Itraconazole The metabolism of Nintedanib can be decreased when combined with Itraconazole. |
Rifabutin | Rifabutin The metabolism of Nintedanib can be increased when combined with Rifabutin. |
Bisoprolol | Bisoprolol The serum concentration of Nintedanib can be increased when it is combined with Bisoprolol. |
Doxazosin | Doxazosin The metabolism of Nintedanib can be decreased when combined with Doxazosin. |
Isradipine | Isradipine The metabolism of Nintedanib can be decreased when combined with Isradipine. |
Omeprazole | Omeprazole The metabolism of Nintedanib can be increased when combined with Omeprazole. |
Cisapride | Cisapride The metabolism of Nintedanib can be decreased when combined with Cisapride. |
Fluvastatin | Fluvastatin The metabolism of Nintedanib can be decreased when combined with Fluvastatin. |
Famciclovir | Famciclovir The metabolism of Nintedanib can be decreased when combined with Famciclovir. |
Fluvoxamine | Fluvoxamine The metabolism of Nintedanib can be decreased when combined with Fluvoxamine. |
Nefazodone | Nefazodone The metabolism of Nintedanib can be decreased when combined with Nefazodone. |
Lamotrigine | Lamotrigine The metabolism of Nintedanib can be increased when combined with Lamotrigine. |
Losartan | Losartan The metabolism of Nintedanib can be decreased when combined with Losartan. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Vinorelbine can be decreased when combined with Nintedanib. |
Lansoprazole | Lansoprazole The metabolism of Nintedanib can be increased when combined with Lansoprazole. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Nintedanib can be decreased when combined with Ifosfamide. |
Nicardipine | Nicardipine The metabolism of Nintedanib can be decreased when combined with Nicardipine. |
Ticlopidine | Ticlopidine The metabolism of Nintedanib can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The metabolism of Saquinavir can be decreased when combined with Nintedanib. |
Dalteparin Injection | Dalteparin Injection The risk or severity of bleeding can be increased when Dalteparin is combined with Nintedanib. |
Gemcitabine Injection | Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Nintedanib. |
Indinavir | Indinavir The metabolism of Nintedanib can be decreased when combined with Indinavir. |
Ritonavir | Ritonavir The serum concentration of Nintedanib can be increased when it is combined with Ritonavir. |
Docetaxel Injection | Docetaxel Injection The metabolism of Nintedanib can be decreased when combined with Docetaxel. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be decreased when combined with Nintedanib. |
Zafirlukast | Zafirlukast The metabolism of Nintedanib can be decreased when combined with Zafirlukast. |
Mirtazapine | Mirtazapine The metabolism of Nintedanib can be decreased when combined with Mirtazapine. |
Topiramate | Topiramate The metabolism of Nintedanib can be increased when combined with Topiramate. |
Nelfinavir | Nelfinavir The metabolism of Nintedanib can be increased when combined with Nelfinavir. |
Fexofenadine | Fexofenadine The serum concentration of Nintedanib can be increased when it is combined with Fexofenadine. |
Azithromycin | Azithromycin The metabolism of Nintedanib can be decreased when combined with Azithromycin. |
Carvedilol | Carvedilol The serum concentration of Nintedanib can be increased when it is combined with Carvedilol. |
Bicalutamide | Bicalutamide The metabolism of Nintedanib can be decreased when combined with Bicalutamide. |
Propafenone | Propafenone The serum concentration of Nintedanib can be increased when it is combined with Propafenone. |
Raloxifene | Raloxifene The metabolism of Nintedanib can be decreased when combined with Raloxifene. |
Irbesartan | Irbesartan The metabolism of Nintedanib can be decreased when combined with Irbesartan. |
Paroxetine | Paroxetine The metabolism of Nintedanib can be decreased when combined with Paroxetine. |
Citalopram | Citalopram The metabolism of Nintedanib can be decreased when combined with Citalopram. |
Efavirenz | Efavirenz The metabolism of Nintedanib can be decreased when combined with Efavirenz. |
Sildenafil | Sildenafil The serum concentration of Nintedanib can be increased when it is combined with Sildenafil. |
Rabeprazole | Rabeprazole The metabolism of Nintedanib can be decreased when combined with Rabeprazole. |
Terbinafine | Terbinafine The metabolism of Nintedanib can be increased when combined with Terbinafine. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists