Rimegepant

Generic name: Pronounced as (ri me' je pant)
Brand names
  • Nurtec® ODT
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 07/15/2021

Rimegepant is used to prevent and treat the symptoms of migraine headaches (severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound or light). Rimegepant is in a class of medications called calcitonin gene-related peptide receptor antagonists. It works by blocking the action of a certain natural substance in the body that causes migraine headaches.

Rimegepant comes as an orally disintegrating tablet (tablet that dissolves quickly in the mouth) to take by mouth. If used to prevent a migraine, it is usually taken every other day. If used to treat a migraine, it is usually taken as a single dose at the first sign of a migraine headache. Do not take more than one dose in a 24-hour period. Your doctor will tell you the maximum number of migraine headaches you should treat with rimegepant tablets in a 30-day period. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take rimegepant exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Do not try to push the orally disintegrating tablet through the foil packaging. Instead, use dry hands to peel back the foil. Immediately take out the tablet and place it on or under your tongue. The tablet will quickly dissolve and can be swallowed with saliva. No water is needed to swallow disintegrating tablets.

Call your doctor if your headaches do not get better or occur more frequently after taking rimegepant.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking rimegepant,

  • tell your doctor and pharmacist if you are allergic to rimegepant, any other medications, or any of the ingredients in rimegepant orally disintegrating tablets. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antifungals such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox, Tolsura), ketoconazole, and voriconazole (Vfend); aprepitant (Emend), clarithromycin, ciprofloxacin (Cipro), conivaptan (Vaprisol), crizotinib (Xalkori), cyclosporine (Gengraf, Neoral, Sandimmune), diltiazem (Cardizem, Cartia, Taztia, Tiazac), dronedarone (Multaq), erythromycin (E.E.S., Eryc, Eryped, Ery-tab), fluvoxamine (Luvox); imatinib (Gleevac); medications for human immunodeficiency virus (HIV) such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra, in Viekira), and saquinavir (Invirase), tipranavir (Aptivus); rifampin (Rifadin, Rimactane, in Rifamate, Rifater), and verapamil (Calan, Verelan, in Tarka). Your doctor may need to change the doses of your medications, how often or if you should take rimegepant, or monitor you carefully for side effects. Many other medications may also interact with rimegepant, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have or have ever had kidney or liver problems.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking rimegepant, call your doctor.

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication.

  • Rimegepant may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • nausea

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

    • shortness of breath

    • difficulty breathing

    • swelling of the face, eyes, mouth, throat, tongue, or lips

    • rash

    • hives

    • itching

  • Rimegepant may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

You should keep a headache diary by writing down when you have headaches and when you take rimegepant.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Delavirdine Delavirdine The metabolism of Rimegepant can be decreased when combined with Delavirdine.
Atorvastatin Atorvastatin The metabolism of Rimegepant can be increased when combined with Atorvastatin.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Rimegepant can be increased when it is combined with Erythromycin.
Paregoric Paregoric The serum concentration of Rimegepant can be increased when it is combined with Morphine.
Reserpine Reserpine The metabolism of Rimegepant can be increased when combined with Reserpine.
Tacrolimus Tacrolimus The serum concentration of Rimegepant can be increased when it is combined with Tacrolimus.
Fluconazole Injection Fluconazole Injection The serum concentration of Rimegepant can be increased when it is combined with Fluconazole.
Meperidine Injection Meperidine Injection The metabolism of Rimegepant can be increased when combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The metabolism of Rimegepant can be increased when combined with Methylprednisolone.
Morphine Injection Morphine Injection The serum concentration of Rimegepant can be increased when it is combined with Morphine.
Cyclosporine Cyclosporine The serum concentration of Rimegepant can be increased when it is combined with Cyclosporine.
Orlistat Orlistat The metabolism of Rimegepant can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Rimegepant can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole The serum concentration of Rimegepant can be increased when it is combined with Pantoprazole.
Telmisartan Telmisartan The serum concentration of Rimegepant can be increased when it is combined with Telmisartan.
Temozolomide Temozolomide The metabolism of Rimegepant can be increased when combined with Temozolomide.
Trimipramine Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Rimegepant.
Modafinil Modafinil The metabolism of Rimegepant can be increased when combined with Modafinil.
Tenofovir Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Rimegepant.
Sirolimus Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Rimegepant.
Zonisamide Zonisamide The serum concentration of Rimegepant can be increased when it is combined with Zonisamide.
Atazanavir Atazanavir The metabolism of Rimegepant can be decreased when combined with Atazanavir.
Eletriptan Eletriptan The metabolism of Rimegepant can be increased when combined with Eletriptan.
Vardenafil Vardenafil The serum concentration of Rimegepant can be increased when it is combined with Vardenafil.
Aprepitant Aprepitant The metabolism of Rimegepant can be decreased when combined with Aprepitant.
Tegaserod Tegaserod The serum concentration of Rimegepant can be increased when it is combined with Tegaserod.
Progesterone Progesterone The metabolism of Rimegepant can be increased when combined with Progesterone.
Rifaximin Rifaximin The metabolism of Rimegepant can be increased when combined with Rifaximin.
Bosentan Bosentan The metabolism of Rimegepant can be increased when combined with Bosentan.
Erlotinib Erlotinib The serum concentration of Rimegepant can be increased when it is combined with Erlotinib.
Voriconazole Voriconazole The metabolism of Rimegepant can be decreased when combined with Voriconazole.
Deferasirox Deferasirox The metabolism of Rimegepant can be increased when combined with Deferasirox.
Tipranavir Tipranavir The metabolism of Rimegepant can be decreased when combined with Tipranavir.
Felbamate Felbamate The metabolism of Rimegepant can be increased when combined with Felbamate.
Ranolazine Ranolazine The serum concentration of Rimegepant can be increased when it is combined with Ranolazine.
Imatinib Imatinib The serum concentration of Rimegepant can be increased when it is combined with Imatinib.
Sitagliptin Sitagliptin The serum concentration of Rimegepant can be increased when it is combined with Sitagliptin.
Gefitinib Gefitinib The serum concentration of Rimegepant can be increased when it is combined with Gefitinib.
Paliperidone Paliperidone The serum concentration of Rimegepant can be increased when it is combined with Paliperidone.
Bortezomib Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Rimegepant.
Posaconazole Posaconazole The metabolism of Rimegepant can be decreased when combined with Posaconazole.
Primaquine Primaquine The metabolism of Rimegepant can be decreased when combined with Primaquine.
Darunavir Darunavir The metabolism of Rimegepant can be decreased when combined with Darunavir.
Sorafenib Sorafenib The serum concentration of Rimegepant can be increased when it is combined with Sorafenib.
Sunitinib Sunitinib The serum concentration of Rimegepant can be increased when it is combined with Sunitinib.
Dronabinol Dronabinol The serum concentration of Rimegepant can be increased when it is combined with Dronabinol.
Lapatinib Lapatinib The serum concentration of Rimegepant can be increased when it is combined with Lapatinib.
Dasatinib Dasatinib The serum concentration of Rimegepant can be increased when it is combined with Dasatinib.
Armodafinil Armodafinil The metabolism of Rimegepant can be increased when combined with Armodafinil.
Temsirolimus Temsirolimus The serum concentration of Rimegepant can be increased when it is combined with Temsirolimus.
Nilotinib Nilotinib The metabolism of Rimegepant can be decreased when combined with Nilotinib.
Toremifene Toremifene The serum concentration of Rimegepant can be increased when it is combined with Toremifene.
Bexarotene Bexarotene The metabolism of Rimegepant can be increased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Rimegepant can be increased when combined with Budesonide.
Etravirine Etravirine The metabolism of Rimegepant can be increased when combined with Etravirine.
Desvenlafaxine Desvenlafaxine The metabolism of Rimegepant can be decreased when combined with Desvenlafaxine.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Rimegepant.
Mitotane Mitotane The metabolism of Rimegepant can be increased when combined with Mitotane.
Rufinamide Rufinamide The metabolism of Rimegepant can be increased when combined with Rufinamide.
Silodosin Silodosin The serum concentration of Rimegepant can be increased when it is combined with Silodosin.
Eltrombopag Eltrombopag The serum concentration of Rimegepant can be increased when it is combined with Eltrombopag.
Milnacipran Milnacipran The metabolism of Rimegepant can be decreased when combined with Milnacipran.
Everolimus Everolimus The serum concentration of Rimegepant can be increased when it is combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Rimegepant can be increased when it is combined with Tolvaptan.
Dronedarone Dronedarone The serum concentration of Rimegepant can be increased when it is combined with Dronedarone.
Romidepsin Injection Romidepsin Injection The serum concentration of Rimegepant can be increased when it is combined with Romidepsin.
Topotecan Topotecan The metabolism of Rimegepant can be increased when combined with Topotecan.
Pazopanib Pazopanib The serum concentration of Rimegepant can be increased when it is combined with Pazopanib.
Tocilizumab Injection Tocilizumab Injection The metabolism of Rimegepant can be increased when combined with Tocilizumab.
Cabazitaxel Injection Cabazitaxel Injection The serum concentration of Rimegepant can be increased when it is combined with Cabazitaxel.
Acetaminophen Injection Acetaminophen Injection The metabolism of Rimegepant can be increased when combined with Acetaminophen.
Linagliptin Linagliptin The serum concentration of Rimegepant can be increased when it is combined with Linagliptin.
Rilpivirine Rilpivirine The serum concentration of Rimegepant can be increased when it is combined with Rilpivirine.
Telaprevir Telaprevir The serum concentration of Rimegepant can be increased when it is combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Rimegepant can be increased when combined with Cyclophosphamide.
Rivaroxaban Rivaroxaban The serum concentration of Rimegepant can be increased when it is combined with Rivaroxaban.
Ticagrelor Ticagrelor The serum concentration of Rimegepant can be increased when it is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Rimegepant.
Vandetanib Vandetanib The serum concentration of Rimegepant can be increased when it is combined with Vandetanib.
Clobazam Clobazam The metabolism of Rimegepant can be increased when combined with Clobazam.
Vemurafenib Vemurafenib The metabolism of Rimegepant can be increased when combined with Vemurafenib.
Vismodegib Vismodegib The serum concentration of Rimegepant can be increased when it is combined with Vismodegib.
Ivacaftor Ivacaftor The serum concentration of Rimegepant can be increased when it is combined with Ivacaftor.
Axitinib Axitinib The serum concentration of Axitinib can be increased when it is combined with Rimegepant.
Crizotinib Crizotinib The serum concentration of Rimegepant can be increased when it is combined with Crizotinib.
Cabergoline Cabergoline The serum concentration of Cabergoline can be increased when it is combined with Rimegepant.
Naloxone Injection Naloxone Injection The metabolism of Rimegepant can be decreased when combined with Naloxone.
Ambrisentan Ambrisentan The serum concentration of Rimegepant can be increased when it is combined with Ambrisentan.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Rimegepant can be increased when it is combined with Carfilzomib.
Enzalutamide Enzalutamide The metabolism of Rimegepant can be increased when combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Rimegepant can be increased when it is combined with Mirabegron.
Regorafenib Regorafenib The serum concentration of Rimegepant can be increased when it is combined with Regorafenib.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Rimegepant.
Corticotropin, Repository Injection Corticotropin, Repository Injection The metabolism of Rimegepant can be increased when combined with Corticotropin.
Teriflunomide Teriflunomide The serum concentration of Rimegepant can be increased when it is combined with Teriflunomide.
Ponatinib Ponatinib The serum concentration of Rimegepant can be increased when it is combined with Ponatinib.
Pomalidomide Pomalidomide The serum concentration of Rimegepant can be increased when it is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Rimegepant can be increased when it is combined with Trastuzumab emtansine.
Apixaban Apixaban The serum concentration of Rimegepant can be increased when it is combined with Apixaban.
Canagliflozin Canagliflozin The serum concentration of Rimegepant can be increased when it is combined with Canagliflozin.
Dabrafenib Dabrafenib The metabolism of Rimegepant can be increased when combined with Dabrafenib.
Trametinib Trametinib The metabolism of Rimegepant can be increased when combined with Trametinib.
Dolutegravir Dolutegravir The serum concentration of Rimegepant can be increased when it is combined with Dolutegravir.
Afatinib Afatinib The serum concentration of Rimegepant can be increased when it is combined with Afatinib.
Perampanel Perampanel The metabolism of Rimegepant can be increased when combined with Perampanel.
Lomitapide Lomitapide The serum concentration of Rimegepant can be increased when it is combined with Lomitapide.
Simeprevir Simeprevir The serum concentration of Rimegepant can be increased when it is combined with Simeprevir.
Sofosbuvir Sofosbuvir The serum concentration of Rimegepant can be increased when it is combined with Sofosbuvir.
Ceritinib Ceritinib The serum concentration of Rimegepant can be increased when it is combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Rimegepant can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Rimegepant can be increased when combined with Eslicarbazepine.
Belinostat Injection Belinostat Injection The serum concentration of Rimegepant can be increased when it is combined with Belinostat.
Idelalisib Idelalisib The serum concentration of Rimegepant can be increased when it is combined with Idelalisib.
Testosterone Injection Testosterone Injection The metabolism of Rimegepant can be increased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Rimegepant can be increased when combined with Oritavancin.
Vorapaxar Vorapaxar The serum concentration of Rimegepant can be increased when it is combined with Vorapaxar.
Suvorexant Suvorexant The serum concentration of Rimegepant can be increased when it is combined with Suvorexant.
Edoxaban Edoxaban The serum concentration of Rimegepant can be increased when it is combined with Edoxaban.
Olaparib Olaparib The serum concentration of Rimegepant can be increased when it is combined with Olaparib.
Nintedanib Nintedanib The serum concentration of Rimegepant can be increased when it is combined with Nintedanib.
Palbociclib Palbociclib The serum concentration of Rimegepant can be increased when it is combined with Palbociclib.
Lenvatinib Lenvatinib The metabolism of Rimegepant can be increased when combined with Lenvatinib.
Panobinostat Panobinostat The serum concentration of Rimegepant can be increased when it is combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The metabolism of Rimegepant can be decreased when combined with Haloperidol.
Isavuconazonium Injection Isavuconazonium Injection The metabolism of Rimegepant can be increased when combined with Isavuconazonium.
Flibanserin Flibanserin The serum concentration of Rimegepant can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant The serum concentration of Rimegepant can be increased when it is combined with Rolapitant.
Prednisolone Prednisolone The metabolism of Rimegepant can be increased when combined with Prednisolone.
Daclatasvir Daclatasvir The serum concentration of Rimegepant can be increased when it is combined with Daclatasvir.
Ziprasidone Injection Ziprasidone Injection The metabolism of Rimegepant can be decreased when combined with Ziprasidone.
Cobimetinib Cobimetinib The serum concentration of Rimegepant can be increased when it is combined with Cobimetinib.
Osimertinib Osimertinib The metabolism of Rimegepant can be increased when combined with Osimertinib.
Alectinib Alectinib The serum concentration of Rimegepant can be increased when it is combined with Alectinib.
Rifapentine Rifapentine The metabolism of Rimegepant can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Rimegepant can be increased when combined with Lesinurad.
Dexamethasone Injection Dexamethasone Injection The metabolism of Rimegepant can be increased when combined with Dexamethasone.
Venetoclax Venetoclax The serum concentration of Rimegepant can be increased when it is combined with Venetoclax.
Cobicistat Cobicistat The metabolism of Rimegepant can be decreased when combined with Cobicistat.
Selexipag Selexipag The serum concentration of Rimegepant can be increased when it is combined with Selexipag.
Rucaparib Rucaparib The serum concentration of Rimegepant can be increased when it is combined with Rucaparib.
Ribociclib Ribociclib The metabolism of Rimegepant can be decreased when combined with Ribociclib.
Brigatinib Brigatinib The metabolism of Rimegepant can be increased when combined with Brigatinib.
Safinamide Safinamide The serum concentration of Rimegepant can be increased when it is combined with Safinamide.
Sarilumab Injection Sarilumab Injection The metabolism of Rimegepant can be increased when combined with Sarilumab.
Midostaurin Midostaurin The metabolism of Rimegepant can be decreased when combined with Midostaurin.
Neratinib Neratinib The serum concentration of Rimegepant can be increased when it is combined with Neratinib.
Enasidenib Enasidenib The metabolism of Rimegepant can be increased when combined with Enasidenib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Rimegepant can be increased when it is combined with Inotuzumab ozogamicin.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Rimegepant can be increased when combined with Fosaprepitant.
Copanlisib Injection Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Rimegepant.
Delafloxacin Delafloxacin The metabolism of Rimegepant can be increased when combined with Delafloxacin.
Abemaciclib Abemaciclib The serum concentration of Rimegepant can be increased when it is combined with Abemaciclib.
Betrixaban Betrixaban The serum concentration of Rimegepant can be increased when it is combined with Betrixaban.
Letermovir Letermovir The serum concentration of Rimegepant can be increased when it is combined with Letermovir.
Ertugliflozin Ertugliflozin The serum concentration of Rimegepant can be increased when it is combined with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection The serum concentration of Rimegepant can be increased when it is combined with Buprenorphine.
Apalutamide Apalutamide The metabolism of Rimegepant can be increased when combined with Apalutamide.
Fostamatinib Fostamatinib The serum concentration of Rimegepant can be increased when it is combined with Fostamatinib.
Avatrombopag Avatrombopag The serum concentration of Rimegepant can be increased when it is combined with Avatrombopag.
Baricitinib Baricitinib The serum concentration of Rimegepant can be increased when it is combined with Baricitinib.
Eliglustat Eliglustat The serum concentration of Rimegepant can be increased when it is combined with Eliglustat.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Rimegepant.
Ivosidenib Ivosidenib The metabolism of Rimegepant can be increased when combined with Ivosidenib.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Rimegepant.
Elagolix Elagolix The serum concentration of Rimegepant can be increased when it is combined with Elagolix.
Cannabidiol Cannabidiol The serum concentration of Rimegepant can be increased when it is combined with Cannabidiol.
Dacomitinib Dacomitinib The serum concentration of Rimegepant can be increased when it is combined with Dacomitinib.
Duvelisib Duvelisib The serum concentration of Rimegepant can be increased when it is combined with Duvelisib.
Omadacycline Omadacycline The serum concentration of Rimegepant can be increased when it is combined with Omadacycline.
Sarecycline Sarecycline The serum concentration of Rimegepant can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The metabolism of Rimegepant can be decreased when combined with Stiripentol.
Talazoparib Talazoparib The serum concentration of Rimegepant can be increased when it is combined with Talazoparib.
Gilteritinib Gilteritinib The serum concentration of Rimegepant can be increased when it is combined with Gilteritinib.
Glasdegib Glasdegib The serum concentration of Rimegepant can be increased when it is combined with Glasdegib.
Lorlatinib Lorlatinib The metabolism of Rimegepant can be increased when combined with Lorlatinib.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Rimegepant.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Rimegepant can be increased when combined with Paclitaxel.
Rifamycin Rifamycin The metabolism of Rimegepant can be increased when combined with Rifamycin.
Erdafitinib Erdafitinib The serum concentration of Rimegepant can be increased when it is combined with Erdafitinib.
Alpelisib Alpelisib The metabolism of Rimegepant can be increased when combined with Alpelisib.
Darolutamide Darolutamide The serum concentration of Rimegepant can be increased when it is combined with Darolutamide.
Entrectinib Entrectinib The serum concentration of Rimegepant can be increased when it is combined with Entrectinib.
Istradefylline Istradefylline The serum concentration of Rimegepant can be increased when it is combined with Istradefylline.
Pitolisant Pitolisant The metabolism of Rimegepant can be increased when combined with Pitolisant.
Fedratinib Fedratinib The serum concentration of Rimegepant can be increased when it is combined with Fedratinib.
Lefamulin Lefamulin The serum concentration of Lefamulin can be increased when it is combined with Rimegepant.
Phenytoin Injection Phenytoin Injection The metabolism of Rimegepant can be increased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Rimegepant can be increased when combined with Fosphenytoin.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Rimegepant.
Lasmiditan Lasmiditan The serum concentration of Rimegepant can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Rimegepant.
Tazemetostat Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Rimegepant.
Cenobamate Cenobamate The serum concentration of Rimegepant can be decreased when it is combined with Cenobamate.
Selumetinib Selumetinib The serum concentration of Rimegepant can be increased when it is combined with Selumetinib.
Tucatinib Tucatinib Tucatinib may decrease the excretion rate of Rimegepant which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Rimegepant.
Ripretinib Ripretinib The serum concentration of Rimegepant can be increased when it is combined with Ripretinib.
Capmatinib Capmatinib The serum concentration of Rimegepant can be increased when it is combined with Capmatinib.
Lemborexant Lemborexant The serum concentration of Rimegepant can be increased when it is combined with Lemborexant.
Fostemsavir Fostemsavir The serum concentration of Rimegepant can be increased when it is combined with Fostemsavir.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Rimegepant.
Pralsetinib Pralsetinib The metabolism of Rimegepant can be increased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Rimegepant can be decreased when it is combined with Satralizumab.
Phenobarbital Phenobarbital The metabolism of Rimegepant can be increased when combined with Phenobarbital.
Primidone Primidone The metabolism of Rimegepant can be increased when combined with Primidone.
Sulfasalazine Sulfasalazine The serum concentration of Rimegepant can be increased when it is combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The metabolism of Rimegepant can be increased when combined with Hydrocortisone.
Dactinomycin Dactinomycin The serum concentration of Rimegepant can be increased when it is combined with Dactinomycin.
Pyridostigmine Pyridostigmine The metabolism of Rimegepant can be increased when combined with Pyridostigmine.
Carbamazepine Carbamazepine The metabolism of Rimegepant can be increased when combined with Carbamazepine.
Loperamide Loperamide The metabolism of Rimegepant can be decreased when combined with Loperamide.
Daunorubicin Daunorubicin The metabolism of Rimegepant can be increased when combined with Daunorubicin.
Griseofulvin Griseofulvin The metabolism of Rimegepant can be increased when combined with Griseofulvin.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Rimegepant.
Loxapine Loxapine The serum concentration of Rimegepant can be increased when it is combined with Loxapine.
Quinine Quinine The metabolism of Rimegepant can be increased when combined with Quinine.
Calcitriol Calcitriol The metabolism of Rimegepant can be increased when combined with Calcitriol.
Sulfinpyrazone Sulfinpyrazone The metabolism of Rimegepant can be increased when combined with Sulfinpyrazone.
Secobarbital Secobarbital The metabolism of Rimegepant can be increased when combined with Secobarbital.
Imipramine Imipramine The serum concentration of Imipramine can be increased when it is combined with Rimegepant.
Probenecid Probenecid The metabolism of Rimegepant can be increased when combined with Probenecid.
Quinidine Quinidine The serum concentration of Rimegepant can be increased when it is combined with Quinidine.
Isoniazid Isoniazid The metabolism of Rimegepant can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Rimegepant can be increased when combined with Rifampicin.
Tamoxifen Tamoxifen The metabolism of Rimegepant can be increased when combined with Tamoxifen.
Methimazole Methimazole The metabolism of Rimegepant can be decreased when combined with Methimazole.
Danazol Danazol The metabolism of Rimegepant can be decreased when combined with Danazol.
Nortriptyline Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Rimegepant.
Clomiphene Clomiphene The serum concentration of Rimegepant can be increased when it is combined with Clomifene.
Colchicine Colchicine The metabolism of Rimegepant can be increased when combined with Colchicine.
Ketoconazole Ketoconazole The metabolism of Rimegepant can be decreased when combined with Ketoconazole.
Vincristine Injection Vincristine Injection The serum concentration of Vincristine can be increased when it is combined with Rimegepant.
Vinblastine Vinblastine The metabolism of Rimegepant can be increased when combined with Vinblastine.
Diltiazem Diltiazem The metabolism of Rimegepant can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Rimegepant can be increased when combined with Nifedipine.
Verapamil Verapamil The serum concentration of Rimegepant can be increased when it is combined with Verapamil.
Etoposide Etoposide The metabolism of Rimegepant can be increased when combined with Etoposide.
Dicloxacillin Dicloxacillin The metabolism of Rimegepant can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Rimegepant can be increased when combined with Nafcillin.
Amiodarone Amiodarone The serum concentration of Rimegepant can be increased when it is combined with Amiodarone.
Lovastatin Lovastatin The metabolism of Rimegepant can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The metabolism of Rimegepant can be decreased when combined with Ciprofloxacin.
Oxiconazole Oxiconazole The metabolism of Rimegepant can be increased when combined with Oxiconazole.
Clozapine Clozapine The metabolism of Rimegepant can be increased when combined with Clozapine.
Clarithromycin Clarithromycin The metabolism of Rimegepant can be decreased when combined with Clarithromycin.
Pravastatin Pravastatin The serum concentration of Rimegepant can be increased when it is combined with Pravastatin.
Simvastatin Simvastatin The serum concentration of Rimegepant can be increased when it is combined with Simvastatin.
Itraconazole Itraconazole The metabolism of Rimegepant can be decreased when combined with Itraconazole.
Rifabutin Rifabutin The metabolism of Rimegepant can be increased when combined with Rifabutin.
Bisoprolol Bisoprolol The serum concentration of Rimegepant can be increased when it is combined with Bisoprolol.
Isradipine Isradipine The metabolism of Rimegepant can be decreased when combined with Isradipine.
Omeprazole Omeprazole The metabolism of Rimegepant can be increased when combined with Omeprazole.
Venlafaxine Venlafaxine Venlafaxine may increase the excretion rate of Rimegepant which could result in a lower serum level and potentially a reduction in efficacy.
Fluvoxamine Fluvoxamine The metabolism of Rimegepant can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Rimegepant can be decreased when combined with Nefazodone.
Lansoprazole Lansoprazole The metabolism of Rimegepant can be increased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Rimegepant can be increased when combined with Ifosfamide.
Nicardipine Nicardipine The metabolism of Rimegepant can be decreased when combined with Nicardipine.
Saquinavir Saquinavir The metabolism of Rimegepant can be decreased when combined with Saquinavir.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Rimegepant.
Ritonavir Ritonavir The metabolism of Rimegepant can be decreased when combined with Ritonavir.
Topiramate Topiramate The metabolism of Rimegepant can be increased when combined with Topiramate.
Nelfinavir Nelfinavir The serum concentration of Rimegepant can be increased when it is combined with Nelfinavir.
Fexofenadine Fexofenadine The serum concentration of Rimegepant can be increased when it is combined with Fexofenadine.
Carvedilol Carvedilol The serum concentration of Rimegepant can be increased when it is combined with Carvedilol.
Propafenone Propafenone The serum concentration of Rimegepant can be increased when it is combined with Propafenone.
Efavirenz Efavirenz The metabolism of Rimegepant can be decreased when combined with Efavirenz.
Sildenafil Sildenafil The serum concentration of Rimegepant can be increased when it is combined with Sildenafil.
Thalidomide Thalidomide The metabolism of Rimegepant can be increased when combined with Thalidomide.
Rabeprazole Rabeprazole The serum concentration of Rimegepant can be increased when it is combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Rimegepant can be increased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists