Temsirolimus

Generic name: Pronounced as (tem'' sir oh' li mus)
Brand names
  • Torisel®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/01/2008

Temsirolimus is used to treat advanced renal cell carcinoma (RCC, a type of cancer that begins in the kidney). Temsirolimus is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that tells the cancer cells to multiply. This may help slow the growth of tumors.

Temsirolimus comes as a solution (liquid) to be given by infusion (slow injection into a vein) over 30 to 60 minutes. It is usually given by a doctor or nurse in a doctor's office or infusion center. Temsirolimus is usually given once every week.

You may experience symptoms such as hives, rash, itching, difficulty breathing or swallowing, swelling of the face, flushing, or chest pain. Tell your doctor or other healthcare provider if you experience these symptoms while you are receiving temsirolimus. Your doctor may prescribe other medications to help prevent or relieve these symptoms. Your doctor will probably give you these medications before you receive each dose of temsirolimus.

Before taking temsirolimus,

  • tell your doctor if you are allergic to temsirolimus, sirolimus, antihistamines, any other medications, polysorbate 80, or any of the ingredients in the temsirolimus solution. Ask your doctor for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); certain antifungal medications such as itraconazole (Sporanox); ketoconazole (Nizoral); and voriconazole (Vfen); clarithromycin (Biaxin); dexamethasone (Decadron); certain medications used to treat HIV/AIDS such as atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir), and saquinavir (Invirase); certain medications for seizures such as carbamazepine (Equetro, Tegretol), phenobarbital (Luminal),and phenytoin (Dilantin, Phenytek); medications to lower cholesterol and lipids; nefazodone; rifabutin (Mycobutin); rifampin (Rifadin, Rifamate, Rifiter); selective serotonin re-uptake inhibitors such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft); sirolimus (Rapamune, Rapamycin); sunitinib (Sutent); and telithromycin (Ketek). Many other medications may also interact with temsirolimus, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Also be sure to tell your doctor and pharmacist if you stop taking one of the medications listed above while you are receiving treatment with temsirolimus.

  • tell your doctor what herbal products you are taking, especially St. John's Wort.

  • tell your doctor if you have or have ever had diabetes, high cholesterol or triglycerides, a tumor in the central nervous system (brain or spinal cord), cancer, or kidney, liver, or lung disease.

  • tell your doctor if you are pregnant or plan to become pregnant, or if you plan to father a child. You or your partner should not become pregnant while you are receiving temsirolimus and for 3 months after treatment with temsirolimus has ended. Talk to your doctor about birth control methods that will work for you. If you or your partner become pregnant while taking temsirolimus, call your doctor immediately. Temsirolimus may harm the fetus.

  • tell your doctor if you are breast-feeding. You should not breastfeed while receiving temsirolimus.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are receiving temsirolimus.

  • you should know that you may be more at risk of getting an infection while you are receiving temsirolimus. Be sure to wash your hands frequently and avoid contact with people who are sick.

  • do not have any vaccinations (e.g., measles, chicken pox, or flu shots) without talking to your doctor.

Do not eat grapefruit or drink grapefruit juice while taking this medication.

If you miss an appointment to receive a dose of temsirolimus, call your doctor right away.

  • Temsirolimus may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • weakness

    • swelling of the eyes, hands, feet, ankles, or lower legs

    • headache

    • itchy, watery, or red eye(s)

    • change in the way things taste

    • swelling, redness, pain, or sores inside the mouth or throat

    • loss of appetite

    • weight loss

    • nausea

    • vomiting

    • constipation

    • frequent need to urinate

    • pain or burning during urination

    • blood in the urine

    • back pain

    • muscle or joint pain

    • bloody nose

    • changes in fingernails or toenails

    • dry skin

    • pale skin

    • excessive tiredness

    • fast heart beat

    • acne

    • difficulty falling asleep or staying asleep

    • depression

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • hives

    • rash

    • itching

    • difficulty breathing or swallowing

    • flushing

    • chest pain

    • shortness of breath

    • fast breathing or panting

    • leg pain, swelling, tenderness, redness, or warmth

    • extreme thirst

    • extreme hunger

    • fever, sore throat, chills, cough, and other signs of infection

    • fainting

    • new or worsening abdominal pain

    • diarrhea

    • red blood in stools

    • decrease in amount of urine

    • blurred vision

    • slow or difficult speech

    • confusion

    • dizziness or faintness

    • weakness or numbness of an arm or leg

  • Temsirolimus may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

This medication will be stored at your doctor's office or clinic.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • seizure

  • hallucinating (seeing things or hearing voices that do not exist)

  • difficulty thinking clearly, understanding reality, or using good judgment

  • cough

  • shortness of breath

  • fever

  • new or worsening abdominal pain

  • panting or fast breathing

  • red blood in stools

  • diarrhea

  • leg pain, swelling, tenderness, redness, or warmth

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to temsirolimus.

Ask your doctor if you have any questions about your treatment with temsirolimus.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Repaglinide Repaglinide The serum concentration of Repaglinide can be increased when it is combined with Temsirolimus.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Temsirolimus.
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Temsirolimus is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Temsirolimus can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Nevirapine can be decreased when combined with Temsirolimus.
Atorvastatin Atorvastatin The risk or severity of adverse effects can be increased when Temsirolimus is combined with Atorvastatin.
Dolasetron Dolasetron The metabolism of Dolasetron can be decreased when combined with Temsirolimus.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Temsirolimus.
Anagrelide Anagrelide The risk or severity of bleeding can be increased when Anagrelide is combined with Temsirolimus.
Cilostazol Cilostazol The metabolism of Temsirolimus can be decreased when combined with Cilostazol.
Clopidogrel Clopidogrel The metabolism of Temsirolimus can be decreased when combined with Clopidogrel.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Temsirolimus can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The risk or severity of angioedema can be increased when Conjugated estrogens is combined with Temsirolimus.
Fenofibrate Fenofibrate The metabolism of Temsirolimus can be decreased when combined with Fenofibrate.
Methylergonovine Methylergonovine The metabolism of Temsirolimus can be decreased when combined with Methylergometrine.
Miglitol Miglitol The therapeutic efficacy of Miglitol can be decreased when used in combination with Temsirolimus.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Temsirolimus.
Paregoric Paregoric The serum concentration of Temsirolimus can be increased when it is combined with Morphine.
Penbutolol Penbutolol The metabolism of Acebutolol can be decreased when combined with Temsirolimus.
Prednisone Prednisone The serum concentration of Temsirolimus can be increased when it is combined with Prednisone.
Reserpine Reserpine The serum concentration of Temsirolimus can be increased when it is combined with Reserpine.
Tacrolimus Tacrolimus The risk or severity of adverse effects can be increased when Tacrolimus is combined with Temsirolimus.
Triamcinolone Triamcinolone Triamcinolone may decrease the excretion rate of Temsirolimus which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection The metabolism of Temsirolimus can be decreased when combined with Doxycycline.
Fluconazole Injection Fluconazole Injection The serum concentration of Temsirolimus can be increased when it is combined with Fluconazole.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Temsirolimus.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Temsirolimus.
Meperidine Injection Meperidine Injection The metabolism of Temsirolimus can be increased when combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The serum concentration of Temsirolimus can be increased when it is combined with Methylprednisolone.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Temsirolimus.
Metronidazole Injection Metronidazole Injection The metabolism of Temsirolimus can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The serum concentration of Temsirolimus can be increased when it is combined with Morphine.
Zidovudine Injection Zidovudine Injection The risk or severity of adverse effects can be increased when Zidovudine is combined with Temsirolimus.
Altretamine Altretamine The metabolism of Amphetamine can be decreased when combined with Temsirolimus.
Cyclosporine Cyclosporine Temsirolimus may increase the immunosuppressive activities of Cyclosporine.
Ondansetron Ondansetron The metabolism of Temsirolimus can be decreased when combined with Ondansetron.
Enoxaparin Injection Enoxaparin Injection The risk or severity of bleeding can be increased when Enoxaparin is combined with Temsirolimus.
Olanzapine Olanzapine The metabolism of Olanzapine can be decreased when combined with Temsirolimus.
Eprosartan Eprosartan The risk or severity of angioedema can be increased when Eprosartan is combined with Temsirolimus.
Hydroxychloroquine Hydroxychloroquine The risk or severity of adverse effects can be increased when Hydroxychloroquine is combined with Temsirolimus.
Orlistat Orlistat The metabolism of Temsirolimus can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Temsirolimus can be increased when combined with Oxcarbazepine.
Telmisartan Telmisartan The risk or severity of angioedema can be increased when Telmisartan is combined with Temsirolimus.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Temsirolimus.
Zaleplon Zaleplon The metabolism of Temsirolimus can be decreased when combined with Zaleplon.
Anakinra Anakinra The metabolism of Temsirolimus can be increased when combined with Anakinra.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Temsirolimus.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of bleeding can be increased when Pentosan polysulfate is combined with Temsirolimus.
Trimipramine Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Temsirolimus.
Etanercept Injection Etanercept Injection The metabolism of Temsirolimus can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Temsirolimus can be increased when combined with Modafinil.
Perindopril Perindopril The risk or severity of angioedema can be increased when Perindopril is combined with Temsirolimus.
Tenofovir Tenofovir The metabolism of Temsirolimus can be decreased when combined with Tenofovir.
Sirolimus Sirolimus The metabolism of Sirolimus can be decreased when combined with Temsirolimus.
Dutasteride Dutasteride The metabolism of Temsirolimus can be decreased when combined with Dutasteride.
Epinephrine Injection Epinephrine Injection The metabolism of Temsirolimus can be decreased when combined with Epinephrine.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Temsirolimus.
Eplerenone Eplerenone The metabolism of Temsirolimus can be decreased when combined with Eplerenone.
Escitalopram Escitalopram The metabolism of Escitalopram can be decreased when combined with Temsirolimus.
Zonisamide Zonisamide The serum concentration of Temsirolimus can be increased when it is combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Temsirolimus can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Temsirolimus can be decreased when combined with Aripiprazole.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Temsirolimus.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Glatiramer is combined with Temsirolimus.
Atazanavir Atazanavir The metabolism of Temsirolimus can be decreased when combined with Atazanavir.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Temsirolimus.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Temsirolimus.
Mefloquine Mefloquine The metabolism of Temsirolimus can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Temsirolimus can be decreased when combined with Rosuvastatin.
Vardenafil Vardenafil The serum concentration of Temsirolimus can be increased when it is combined with Vardenafil.
Aprepitant Aprepitant The metabolism of Temsirolimus can be decreased when combined with Aprepitant.
Tegaserod Tegaserod The serum concentration of Tegaserod can be increased when it is combined with Temsirolimus.
Tadalafil Tadalafil The metabolism of Temsirolimus can be decreased when combined with Tadalafil.
Progesterone Progesterone The metabolism of Temsirolimus can be increased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Temsirolimus.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Temsirolimus.
Infliximab Injection Infliximab Injection The metabolism of Temsirolimus can be increased when combined with Infliximab.
Protriptyline Protriptyline The metabolism of Protriptyline can be decreased when combined with Temsirolimus.
Rifaximin Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Temsirolimus.
Duloxetine Duloxetine The metabolism of Temsirolimus can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Temsirolimus can be decreased when combined with Norethisterone.
Bosentan Bosentan The metabolism of Temsirolimus can be increased when combined with Bosentan.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Natalizumab.
Erlotinib Erlotinib The metabolism of Temsirolimus can be decreased when combined with Erlotinib.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be decreased when used in combination with Temsirolimus.
Palifermin Palifermin The therapeutic efficacy of Palifermin can be decreased when used in combination with Temsirolimus.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Temsirolimus.
Voriconazole Voriconazole The serum concentration of Temsirolimus can be increased when it is combined with Voriconazole.
Dextroamphetamine Dextroamphetamine The metabolism of Amphetamine can be decreased when combined with Temsirolimus.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Temsirolimus.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Temsirolimus.
Pramlintide Injection Pramlintide Injection The therapeutic efficacy of Pramlintide can be decreased when used in combination with Temsirolimus.
Exenatide Injection Exenatide Injection The therapeutic efficacy of Exenatide can be decreased when used in combination with Temsirolimus.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Temsirolimus.
Fentanyl Fentanyl The metabolism of Temsirolimus can be decreased when combined with Fentanyl.
Pregabalin Pregabalin The risk or severity of angioedema can be increased when Pregabalin is combined with Temsirolimus.
Deferasirox Deferasirox The metabolism of Temsirolimus can be increased when combined with Deferasirox.
Tipranavir Tipranavir The serum concentration of Temsirolimus can be increased when it is combined with Tipranavir.
Felbamate Felbamate The metabolism of Temsirolimus can be increased when combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be decreased when used in combination with Temsirolimus.
Ranolazine Ranolazine The serum concentration of Temsirolimus can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Temsirolimus can be increased when combined with Abatacept.
Imatinib Imatinib The metabolism of Temsirolimus can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The serum concentration of Temsirolimus can be increased when it is combined with Sitagliptin.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Temsirolimus.
Gefitinib Gefitinib The metabolism of Temsirolimus can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The serum concentration of Temsirolimus can be increased when it is combined with Paliperidone.
Bortezomib Bortezomib The serum concentration of Temsirolimus can be increased when it is combined with Bortezomib.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Temsirolimus.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Temsirolimus.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Temsirolimus.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Temsirolimus.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Temsirolimus.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Temsirolimus.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Temsirolimus.
Posaconazole Posaconazole The metabolism of Posaconazole can be decreased when combined with Temsirolimus.
Primaquine Primaquine The metabolism of Temsirolimus can be decreased when combined with Primaquine.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Temsirolimus.
Darunavir Darunavir The serum concentration of Temsirolimus can be increased when it is combined with Darunavir.
Pemetrexed Injection Pemetrexed Injection The risk or severity of adverse effects can be increased when Pemetrexed is combined with Temsirolimus.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Temsirolimus.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Vorinostat is combined with Temsirolimus.
Sorafenib Sorafenib The serum concentration of Temsirolimus can be increased when it is combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Temsirolimus can be decreased when combined with Sunitinib.
Lapatinib Lapatinib The serum concentration of Temsirolimus can be increased when it is combined with Lapatinib.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Temsirolimus.
Mexiletine Mexiletine The metabolism of Mexiletine can be decreased when combined with Temsirolimus.
Armodafinil Armodafinil The metabolism of Temsirolimus can be increased when combined with Armodafinil.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Temsirolimus.
Ivermectin Ivermectin The metabolism of Temsirolimus can be increased when combined with Ivermectin.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Nelarabine is combined with Temsirolimus.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Temsirolimus.
Nilotinib Nilotinib The serum concentration of Temsirolimus can be increased when it is combined with Nilotinib.
Toremifene Toremifene The serum concentration of Temsirolimus can be increased when it is combined with Toremifene.
Bexarotene Bexarotene The metabolism of Temsirolimus can be increased when combined with Bexarotene.
Budesonide Budesonide The serum concentration of Temsirolimus can be increased when it is combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Temsirolimus can be decreased when combined with Chloramphenicol.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Temsirolimus.
Etravirine Etravirine The metabolism of Temsirolimus can be increased when combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Temsirolimus can be decreased when combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The metabolism of Temsirolimus can be decreased when combined with Desvenlafaxine.
Cevimeline Cevimeline The metabolism of Cevimeline can be decreased when combined with Temsirolimus.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Temsirolimus.
Tretinoin Tretinoin The metabolism of Temsirolimus can be decreased when combined with Tretinoin.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Temsirolimus.
Pilocarpine Pilocarpine The metabolism of Temsirolimus can be decreased when combined with Pilocarpine.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Temsirolimus.
Certolizumab Injection Certolizumab Injection The metabolism of Temsirolimus can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Temsirolimus can be decreased when combined with Ixabepilone.
Irinotecan Injection Irinotecan Injection The metabolism of Temsirolimus can be decreased when combined with Irinotecan.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Temsirolimus.
Praziquantel Praziquantel The metabolism of Temsirolimus can be decreased when combined with Praziquantel.
Mitotane Mitotane The metabolism of Temsirolimus can be increased when combined with Mitotane.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Temsirolimus.
Rufinamide Rufinamide The metabolism of Temsirolimus can be increased when combined with Rufinamide.
Silodosin Silodosin The serum concentration of Silodosin can be increased when it is combined with Temsirolimus.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Temsirolimus.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Temsirolimus.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Temsirolimus.
Milnacipran Milnacipran The metabolism of Temsirolimus can be decreased when combined with Milnacipran.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Temsirolimus.
Betaxolol Betaxolol The metabolism of Betaxolol can be decreased when combined with Temsirolimus.
Iloperidone Iloperidone The metabolism of Temsirolimus can be decreased when combined with Iloperidone.
Prasugrel Prasugrel The risk or severity of bleeding can be increased when Prasugrel is combined with Temsirolimus.
Lacosamide Lacosamide The metabolism of Temsirolimus can be decreased when combined with Lacosamide.
Everolimus Everolimus The serum concentration of Temsirolimus can be increased when it is combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Temsirolimus.
Dronedarone Dronedarone The serum concentration of Temsirolimus can be increased when it is combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Pralatrexate.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Temsirolimus.
Saxagliptin Saxagliptin The metabolism of Temsirolimus can be decreased when combined with Saxagliptin.
Romidepsin Injection Romidepsin Injection The metabolism of Temsirolimus can be decreased when combined with Romidepsin.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Temsirolimus.
Topotecan Topotecan The serum concentration of Topotecan can be increased when it is combined with Temsirolimus.
Golimumab Injection Golimumab Injection The metabolism of Temsirolimus can be increased when combined with Golimumab.
Pazopanib Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Temsirolimus.
Albendazole Albendazole The metabolism of Temsirolimus can be decreased when combined with Albendazole.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be decreased when combined with Temsirolimus.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Temsirolimus.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Temsirolimus.
Dabigatran Dabigatran The risk or severity of bleeding can be increased when Dabigatran is combined with Temsirolimus.
Liraglutide Injection Liraglutide Injection The therapeutic efficacy of Liraglutide can be decreased when used in combination with Temsirolimus.
Tocilizumab Injection Tocilizumab Injection The metabolism of Temsirolimus can be increased when combined with Tocilizumab.
Fingolimod Fingolimod Temsirolimus may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Temsirolimus.
Acetaminophen Injection Acetaminophen Injection The metabolism of Temsirolimus can be increased when combined with Acetaminophen.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Temsirolimus.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Temsirolimus can be decreased when combined with Aldesleukin.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Temsirolimus.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Belimumab.
Azilsartan Azilsartan The risk or severity of angioedema can be increased when Temsirolimus is combined with Azilsartan medoxomil.
Busulfan Injection Busulfan Injection The risk or severity of adverse effects can be increased when Busulfan is combined with Temsirolimus.
Roflumilast Roflumilast Roflumilast may increase the immunosuppressive activities of Temsirolimus.
Linagliptin Linagliptin The serum concentration of Temsirolimus can be increased when it is combined with Linagliptin.
Rilpivirine Rilpivirine The metabolism of Temsirolimus can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The serum concentration of Temsirolimus can be increased when it is combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Temsirolimus can be increased when combined with Cyclophosphamide.
Rivaroxaban Rivaroxaban The metabolism of Temsirolimus can be decreased when combined with Rivaroxaban.
Ticagrelor Ticagrelor The serum concentration of Temsirolimus can be increased when it is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Temsirolimus.
Ruxolitinib Ruxolitinib The risk or severity of adverse effects can be increased when Temsirolimus is combined with Ruxolitinib.
Vandetanib Vandetanib The serum concentration of Temsirolimus can be increased when it is combined with Vandetanib.
Clobazam Clobazam The metabolism of Temsirolimus can be increased when combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Temsirolimus can be increased when it is combined with Vemurafenib.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Belatacept.
Ivacaftor Ivacaftor The serum concentration of Temsirolimus can be increased when it is combined with Ivacaftor.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Temsirolimus.
Axitinib Axitinib The metabolism of Temsirolimus can be decreased when combined with Axitinib.
Crizotinib Crizotinib The metabolism of Temsirolimus can be decreased when combined with Crizotinib.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Temsirolimus.
Cabergoline Cabergoline The metabolism of Temsirolimus can be decreased when combined with Cabergoline.
Naloxone Injection Naloxone Injection The metabolism of Temsirolimus can be decreased when combined with Naloxone.
Ambrisentan Ambrisentan The metabolism of Temsirolimus can be decreased when combined with Ambrisentan.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Temsirolimus.
Fondaparinux Injection Fondaparinux Injection The risk or severity of bleeding can be increased when Fondaparinux is combined with Temsirolimus.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Temsirolimus.
Iloprost Iloprost The risk or severity of bleeding can be increased when Iloprost is combined with Temsirolimus.
Enzalutamide Enzalutamide The serum concentration of Temsirolimus can be increased when it is combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Temsirolimus can be increased when it is combined with Mirabegron.
Regorafenib Regorafenib The serum concentration of Temsirolimus can be increased when it is combined with Regorafenib.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Temsirolimus.
Corticotropin, Repository Injection Corticotropin, Repository Injection The serum concentration of Temsirolimus can be increased when it is combined with Corticotropin.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Temsirolimus is combined with Teriflunomide.
Lorcaserin Lorcaserin The therapeutic efficacy of Mecasermin can be decreased when used in combination with Temsirolimus.
Icosapent Ethyl Icosapent Ethyl The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Temsirolimus.
Tofacitinib Tofacitinib Temsirolimus may increase the immunosuppressive activities of Tofacitinib.
Alogliptin Alogliptin The therapeutic efficacy of Alogliptin can be decreased when used in combination with Temsirolimus.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Temsirolimus is combined with Dimethyl fumarate.
Ponatinib Ponatinib The serum concentration of Temsirolimus can be increased when it is combined with Ponatinib.
Pomalidomide Pomalidomide The serum concentration of Temsirolimus can be increased when it is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Temsirolimus can be decreased when combined with Trastuzumab emtansine.
Apixaban Apixaban The metabolism of Temsirolimus can be decreased when combined with Apixaban.
Canagliflozin Canagliflozin The serum concentration of Temsirolimus can be increased when it is combined with Canagliflozin.
Dabrafenib Dabrafenib The metabolism of Temsirolimus can be increased when combined with Dabrafenib.
Trametinib Trametinib The metabolism of Temsirolimus can be increased when combined with Trametinib.
Dolutegravir Dolutegravir The serum concentration of Dolutegravir can be increased when it is combined with Temsirolimus.
Afatinib Afatinib The serum concentration of Afatinib can be increased when it is combined with Temsirolimus.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Temsirolimus.
Vortioxetine Vortioxetine The metabolism of Temsirolimus can be decreased when combined with Vortioxetine.
Perampanel Perampanel The metabolism of Temsirolimus can be increased when combined with Perampanel.
Ibrutinib Ibrutinib The metabolism of Temsirolimus can be decreased when combined with Ibrutinib.
Lomitapide Lomitapide The serum concentration of Temsirolimus can be increased when it is combined with Lomitapide.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Obinutuzumab.
Simeprevir Simeprevir The serum concentration of Temsirolimus can be increased when it is combined with Simeprevir.
Sofosbuvir Sofosbuvir The serum concentration of Sofosbuvir can be increased when it is combined with Temsirolimus.
Dapagliflozin Dapagliflozin The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Temsirolimus.
Apremilast Apremilast The metabolism of Temsirolimus can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Temsirolimus can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Temsirolimus can be increased when combined with Siltuximab.
Albiglutide Injection Albiglutide Injection The therapeutic efficacy of Albiglutide can be decreased when used in combination with Temsirolimus.
Eslicarbazepine Eslicarbazepine The metabolism of Temsirolimus can be increased when combined with Eslicarbazepine.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Belinostat is combined with Temsirolimus.
Idelalisib Idelalisib The risk or severity of adverse effects can be increased when Temsirolimus is combined with Idelalisib.
Testosterone Injection Testosterone Injection The metabolism of Temsirolimus can be increased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Temsirolimus can be increased when combined with Oritavancin.
Empagliflozin Empagliflozin The therapeutic efficacy of Empagliflozin can be decreased when used in combination with Temsirolimus.
Vorapaxar Vorapaxar The serum concentration of Temsirolimus can be increased when it is combined with Vorapaxar.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Temsirolimus.
Suvorexant Suvorexant The serum concentration of Temsirolimus can be increased when it is combined with Suvorexant.
Dulaglutide Injection Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be decreased when used in combination with Temsirolimus.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Temsirolimus.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Temsirolimus can be decreased when combined with Olaparib.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Blinatumomab.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Temsirolimus.
Tasimelteon Tasimelteon The metabolism of Temsirolimus can be decreased when combined with Tasimelteon.
Lanreotide Injection Lanreotide Injection The metabolism of Temsirolimus can be decreased when combined with Lanreotide.
Pirfenidone Pirfenidone The risk or severity of adverse effects can be increased when Pirfenidone is combined with Temsirolimus.
Nintedanib Nintedanib The metabolism of Temsirolimus can be decreased when combined with Nintedanib.
Secukinumab Injection Secukinumab Injection The metabolism of Temsirolimus can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Temsirolimus can be decreased when combined with Risperidone.
Palbociclib Palbociclib The serum concentration of Temsirolimus can be increased when it is combined with Palbociclib.
Insulin Human Inhalation Insulin Human Inhalation The therapeutic efficacy of Insulin human can be decreased when used in combination with Temsirolimus.
Lenvatinib Lenvatinib The metabolism of Temsirolimus can be increased when combined with Lenvatinib.
Naloxegol Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Temsirolimus.
Panobinostat Panobinostat The serum concentration of Temsirolimus can be increased when it is combined with Panobinostat.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The serum concentration of Temsirolimus can be increased when it is combined with Haloperidol.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Temsirolimus can be increased when it is combined with Isavuconazonium.
Flibanserin Flibanserin The serum concentration of Temsirolimus can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant The serum concentration of Temsirolimus can be increased when it is combined with Rolapitant.
Prednisolone Prednisolone The serum concentration of Temsirolimus can be increased when it is combined with Prednisolone.
Daclatasvir Daclatasvir The serum concentration of Temsirolimus can be increased when it is combined with Daclatasvir.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Temsirolimus.
Ziprasidone Injection Ziprasidone Injection The metabolism of Temsirolimus can be decreased when combined with Ziprasidone.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Temsirolimus.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Temsirolimus.
Cobimetinib Cobimetinib The serum concentration of Temsirolimus can be increased when it is combined with Cobimetinib.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Mepolizumab.
Trabectedin Injection Trabectedin Injection The metabolism of Temsirolimus can be decreased when combined with Trabectedin.
Osimertinib Osimertinib The metabolism of Temsirolimus can be increased when combined with Osimertinib.
Rifapentine Rifapentine The metabolism of Temsirolimus can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Temsirolimus can be increased when combined with Lesinurad.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Temsirolimus can be decreased when combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The serum concentration of Temsirolimus can be increased when it is combined with Dexamethasone.
Defibrotide Injection Defibrotide Injection The risk or severity of bleeding can be increased when Defibrotide is combined with Temsirolimus.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Ixekizumab.
Venetoclax Venetoclax The serum concentration of Temsirolimus can be increased when it is combined with Venetoclax.
Cobicistat Cobicistat The serum concentration of Temsirolimus can be increased when it is combined with Cobicistat.
Selexipag Selexipag The serum concentration of Temsirolimus can be increased when it is combined with Selexipag.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Temsirolimus.
Rucaparib Rucaparib The serum concentration of Temsirolimus can be increased when it is combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be decreased when used in combination with Temsirolimus.
Ribociclib Ribociclib The metabolism of Temsirolimus can be decreased when combined with Ribociclib.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Brodalumab.
Brigatinib Brigatinib The metabolism of Temsirolimus can be increased when combined with Brigatinib.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Temsirolimus.
Deutetrabenazine Deutetrabenazine The metabolism of Temsirolimus can be decreased when combined with Deutetrabenazine.
Valbenazine Valbenazine The metabolism of Temsirolimus can be decreased when combined with Valbenazine.
Deflazacort Deflazacort The serum concentration of Temsirolimus can be increased when it is combined with Deflazacort.
Safinamide Safinamide The metabolism of Temsirolimus can be decreased when combined with Safinamide.
Ocrelizumab Injection Ocrelizumab Injection Ocrelizumab may increase the immunosuppressive activities of Temsirolimus.
Sarilumab Injection Sarilumab Injection The metabolism of Temsirolimus can be increased when combined with Sarilumab.
Midostaurin Midostaurin The metabolism of Temsirolimus can be increased when combined with Midostaurin.
Neratinib Neratinib The serum concentration of Temsirolimus can be increased when it is combined with Neratinib.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Guselkumab.
Enasidenib Enasidenib The serum concentration of Temsirolimus can be increased when it is combined with Enasidenib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Temsirolimus.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Temsirolimus can be increased when combined with Fosaprepitant.
Copanlisib Injection Copanlisib Injection The metabolism of Temsirolimus can be decreased when combined with Copanlisib.
Abemaciclib Abemaciclib The serum concentration of Abemaciclib can be increased when it is combined with Temsirolimus.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Temsirolimus.
Acalabrutinib Acalabrutinib The metabolism of Temsirolimus can be decreased when combined with Acalabrutinib.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Temsirolimus.
Letermovir Letermovir The metabolism of Temsirolimus can be decreased when combined with Letermovir.
Semaglutide Injection Semaglutide Injection The therapeutic efficacy of Semaglutide can be decreased when used in combination with Temsirolimus.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Temsirolimus.
Ertugliflozin Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Temsirolimus.
Buprenorphine Injection Buprenorphine Injection The metabolism of Temsirolimus can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The serum concentration of Temsirolimus can be decreased when it is combined with Apalutamide.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Temsirolimus.
Fostamatinib Fostamatinib The metabolism of Temsirolimus can be decreased when combined with Fostamatinib.
Avatrombopag Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Temsirolimus.
Baricitinib Baricitinib The risk or severity of adverse effects can be increased when Baricitinib is combined with Temsirolimus.
Lofexidine Lofexidine The metabolism of Lofexidine can be decreased when combined with Temsirolimus.
Eliglustat Eliglustat The serum concentration of Eliglustat can be increased when it is combined with Temsirolimus.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Temsirolimus.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Temsirolimus.
Ivosidenib Ivosidenib The serum concentration of Temsirolimus can be increased when it is combined with Ivosidenib.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Temsirolimus.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Temsirolimus.
Doravirine Doravirine The metabolism of Temsirolimus can be decreased when combined with Doravirine.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Temsirolimus.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Temsirolimus.
Dacomitinib Dacomitinib The serum concentration of Temsirolimus can be increased when it is combined with Dacomitinib.
Duvelisib Duvelisib The metabolism of Temsirolimus can be decreased when combined with Duvelisib.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Temsirolimus.
Sarecycline Sarecycline The serum concentration of Temsirolimus can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The metabolism of Temsirolimus can be decreased when combined with Stiripentol.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Temsirolimus.
Gilteritinib Gilteritinib The metabolism of Temsirolimus can be decreased when combined with Gilteritinib.
Glasdegib Glasdegib The serum concentration of Temsirolimus can be increased when it is combined with Glasdegib.
Lorlatinib Lorlatinib The metabolism of Temsirolimus can be decreased when combined with Lorlatinib.
Larotrectinib Larotrectinib The serum concentration of Temsirolimus can be increased when it is combined with Larotrectinib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Temsirolimus.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Temsirolimus can be increased when combined with Paclitaxel.
Rifamycin Rifamycin The metabolism of Temsirolimus can be increased when combined with Rifamycin.
Prucalopride Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Temsirolimus.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Temsirolimus can be increased when combined with Emapalumab.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Temsirolimus is combined with Siponimod.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Caplacizumab is combined with Temsirolimus.
Erdafitinib Erdafitinib The serum concentration of Temsirolimus can be increased when it is combined with Erdafitinib.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Temsirolimus is combined with Risankizumab.
Alpelisib Alpelisib The metabolism of Temsirolimus can be increased when combined with Alpelisib.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Temsirolimus.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Temsirolimus.
Triclabendazole Triclabendazole The metabolism of Temsirolimus can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The serum concentration of Entrectinib can be increased when it is combined with Temsirolimus.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Temsirolimus.
Pitolisant Pitolisant The serum concentration of Temsirolimus can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The serum concentration of Fedratinib can be increased when it is combined with Temsirolimus.
Lefamulin Lefamulin Temsirolimus may decrease the excretion rate of Lefamulin which could result in a higher serum level.
Phenytoin Injection Phenytoin Injection The metabolism of Temsirolimus can be increased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Temsirolimus can be increased when combined with Fosphenytoin.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Temsirolimus.
Voxelotor Voxelotor The serum concentration of Temsirolimus can be increased when it is combined with Voxelotor.
Lasmiditan Lasmiditan The serum concentration of Temsirolimus can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Temsirolimus.
Tazemetostat Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Temsirolimus.
Cenobamate Cenobamate The serum concentration of Temsirolimus can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod The risk or severity of adverse effects can be increased when Temsirolimus is combined with Ozanimod.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Temsirolimus.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Temsirolimus.
Tucatinib Tucatinib Temsirolimus may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Temsirolimus.
Ripretinib Ripretinib The serum concentration of Ripretinib can be increased when it is combined with Temsirolimus.
Capmatinib Capmatinib The serum concentration of Temsirolimus can be increased when it is combined with Capmatinib.
Lemborexant Lemborexant The metabolism of Lemborexant can be decreased when combined with Temsirolimus.
Fostemsavir Fostemsavir The serum concentration of Fostemsavir can be increased when it is combined with Temsirolimus.
Octreotide Octreotide The serum concentration of Temsirolimus can be increased when it is combined with Octreotide.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Temsirolimus.
Pralsetinib Pralsetinib The serum concentration of Pralsetinib can be increased when it is combined with Temsirolimus.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Temsirolimus can be decreased when it is combined with Satralizumab.
Relugolix Relugolix The serum concentration of Relugolix can be increased when it is combined with Temsirolimus.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Temsirolimus can be decreased when combined with Drospirenone.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The metabolism of Temsirolimus can be increased when combined with Vitamin E.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Temsirolimus.
Indomethacin Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Temsirolimus.
Trazodone Trazodone The metabolism of Temsirolimus can be decreased when combined with Trazodone.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Temsirolimus.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Temsirolimus.
Phenobarbital Phenobarbital The metabolism of Temsirolimus can be increased when combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Methotrexate is combined with Temsirolimus.
Primidone Primidone The metabolism of Temsirolimus can be increased when combined with Primidone.
Chlorpromazine Chlorpromazine The metabolism of Temsirolimus can be increased when combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Temsirolimus can be decreased when combined with Diazepam.
Lorazepam Lorazepam The metabolism of Temsirolimus can be decreased when combined with Lorazepam.
Carmustine Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Temsirolimus.
Codeine Codeine The metabolism of Codeine can be decreased when combined with Temsirolimus.
Bromocriptine Bromocriptine The metabolism of Temsirolimus can be decreased when combined with Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Temsirolimus can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Temsirolimus can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Temsirolimus.
Ergoloid Mesylates Ergoloid Mesylates The serum concentration of Ergoloid mesylate can be increased when it is combined with Temsirolimus.
Tetracycline Tetracycline The metabolism of Temsirolimus can be decreased when combined with Tetracycline.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Temsirolimus.
Prochlorperazine Prochlorperazine The metabolism of Temsirolimus can be decreased when combined with Prochlorperazine.
Thioridazine Thioridazine The metabolism of Thioridazine can be decreased when combined with Temsirolimus.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Temsirolimus.
Dapsone Dapsone The metabolism of Temsirolimus can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Temsirolimus.
Oxycodone Oxycodone The metabolism of Temsirolimus can be decreased when combined with Oxycodone.
Methadone Methadone The metabolism of Temsirolimus can be increased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Temsirolimus can be decreased when combined with Oxybutynin.
Benztropine Benztropine The metabolism of Benzatropine can be decreased when combined with Temsirolimus.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Temsirolimus.
Ibuprofen Ibuprofen The risk or severity of angioedema can be increased when Ibuprofen is combined with Temsirolimus.
Orphenadrine Orphenadrine The metabolism of Temsirolimus can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Perphenazine can be decreased when combined with Temsirolimus.
Azathioprine Azathioprine The risk or severity of adverse effects can be increased when Azathioprine is combined with Temsirolimus.
Phentermine Phentermine The metabolism of Temsirolimus can be decreased when combined with Phentermine.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Temsirolimus.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Temsirolimus.
Hydrocortisone Hydrocortisone The serum concentration of Temsirolimus can be increased when it is combined with Hydrocortisone.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Temsirolimus.
Doxorubicin Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Temsirolimus.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with Temsirolimus.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Temsirolimus.
Dactinomycin Dactinomycin The serum concentration of Dactinomycin can be increased when it is combined with Temsirolimus.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Temsirolimus.
Clonidine Clonidine The metabolism of Temsirolimus can be decreased when combined with Clonidine.
Hydralazine Hydralazine The metabolism of Temsirolimus can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Temsirolimus can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Temsirolimus can be increased when combined with Warfarin.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Temsirolimus.
Promethazine Promethazine The metabolism of Promethazine can be decreased when combined with Temsirolimus.
Daunorubicin Daunorubicin The metabolism of Temsirolimus can be decreased when combined with Daunorubicin.
Griseofulvin Griseofulvin The metabolism of Temsirolimus can be increased when combined with Griseofulvin.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Temsirolimus.
Loxapine Loxapine The serum concentration of Temsirolimus can be increased when it is combined with Loxapine.
Chloroquine Chloroquine The metabolism of Temsirolimus can be decreased when combined with Chloroquine.
Quinine Quinine The serum concentration of Quinine can be increased when it is combined with Temsirolimus.
Calcitriol Calcitriol The metabolism of Temsirolimus can be increased when combined with Calcitriol.
Sulfinpyrazone Sulfinpyrazone The metabolism of Temsirolimus can be increased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Chlorothiazide is combined with Temsirolimus.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Temsirolimus.
Secobarbital Secobarbital The metabolism of Temsirolimus can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Temsirolimus can be decreased when combined with Desipramine.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Temsirolimus.
Imipramine Imipramine The metabolism of Temsirolimus can be decreased when combined with Imipramine.
Probenecid Probenecid The metabolism of Temsirolimus can be increased when combined with Probenecid.
Quinidine Quinidine The serum concentration of Quinidine can be increased when it is combined with Temsirolimus.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Temsirolimus.
Isoniazid Isoniazid The metabolism of Temsirolimus can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Temsirolimus can be increased when combined with Rifampicin.
Disopyramide Disopyramide Temsirolimus may increase the QTc-prolonging activities of Disopyramide.
Valproic Acid Valproic Acid The metabolism of Temsirolimus can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Temsirolimus can be increased when combined with Tamoxifen.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Temsirolimus.
Levothyroxine Levothyroxine The serum concentration of Levothyroxine can be decreased when it is combined with Temsirolimus.
Methimazole Methimazole The metabolism of Temsirolimus can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Temsirolimus.
Chlorpropamide Chlorpropamide The therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Temsirolimus.
Tolbutamide Tolbutamide The therapeutic efficacy of Tolbutamide can be decreased when used in combination with Temsirolimus.
Tolazamide Tolazamide The therapeutic efficacy of Tolazamide can be decreased when used in combination with Temsirolimus.
Dextromethorphan Dextromethorphan The metabolism of Temsirolimus can be decreased when combined with Dextromethorphan.
Niacin Niacin The metabolism of Temsirolimus can be decreased when combined with Niacin.
Chlorpheniramine Chlorpheniramine The metabolism of Temsirolimus can be decreased when combined with Chlorpheniramine.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Temsirolimus.
Methyclothiazide Methyclothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Temsirolimus.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Hydrochlorothiazide is combined with Temsirolimus.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Temsirolimus.
Danazol Danazol The metabolism of Temsirolimus can be decreased when combined with Danazol.
Disulfiram Disulfiram The metabolism of Temsirolimus can be decreased when combined with Disulfiram.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Temsirolimus.
Nortriptyline Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Temsirolimus.
Amphotericin B Injection Amphotericin B Injection The metabolism of Temsirolimus can be decreased when combined with Amphotericin B.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Temsirolimus.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Temsirolimus.
Allopurinol Allopurinol The risk or severity of adverse effects can be increased when Allopurinol is combined with Temsirolimus.
Clomiphene Clomiphene The serum concentration of Clomifene can be increased when it is combined with Temsirolimus.
Fluorouracil Injection Fluorouracil Injection The risk or severity of adverse effects can be increased when Fluorouracil is combined with Temsirolimus.
Colchicine Colchicine The serum concentration of Colchicine can be increased when it is combined with Temsirolimus.
Cephalexin Cephalexin The metabolism of Temsirolimus can be decreased when combined with Cephalexin.
Dacarbazine Dacarbazine The risk or severity of adverse effects can be increased when Dacarbazine is combined with Temsirolimus.
Acetazolamide Acetazolamide The metabolism of Temsirolimus can be decreased when combined with Acetazolamide.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Temsirolimus.
Ketoconazole Ketoconazole The serum concentration of the active metabolites of Temsirolimus can be increased when Temsirolimus is used in combination with Ketoconazole.
Thiotepa Injection Thiotepa Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Temsirolimus.
Vincristine Injection Vincristine Injection The excretion of Vincristine can be decreased when combined with Temsirolimus.
Captopril Captopril The risk or severity of angioedema can be increased when Temsirolimus is combined with Captopril.
Dipyridamole Dipyridamole The risk or severity of bleeding can be increased when Dipyridamole is combined with Temsirolimus.
Vinblastine Vinblastine The metabolism of Temsirolimus can be increased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Temsirolimus can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine The metabolism of Hydroxyzine can be decreased when combined with Temsirolimus.
Aspirin Aspirin The risk or severity of angioedema can be increased when Acetylsalicylic acid is combined with Temsirolimus.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Temsirolimus.
Alprazolam Alprazolam The serum concentration of Alprazolam can be increased when it is combined with Temsirolimus.
Triazolam Triazolam The serum concentration of Triazolam can be increased when it is combined with Temsirolimus.
Diltiazem Diltiazem The metabolism of Temsirolimus can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Temsirolimus can be increased when combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Temsirolimus.
Verapamil Verapamil The serum concentration of Temsirolimus can be increased when it is combined with Verapamil.
Atenolol Atenolol The metabolism of Atenolol can be decreased when combined with Temsirolimus.
Pindolol Pindolol The metabolism of Pindolol can be decreased when combined with Temsirolimus.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Temsirolimus.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Temsirolimus.
Etoposide Etoposide The metabolism of Etoposide can be decreased when combined with Temsirolimus.
Glyburide Glyburide The metabolism of Temsirolimus can be decreased when combined with Glyburide.
Glipizide Glipizide The therapeutic efficacy of Glipizide can be decreased when used in combination with Temsirolimus.
Dicloxacillin Dicloxacillin The metabolism of Temsirolimus can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Temsirolimus can be increased when combined with Nafcillin.
Pentoxifylline Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Temsirolimus.
Pentamidine Injection Pentamidine Injection The metabolism of Temsirolimus can be decreased when combined with Pentamidine.
Labetalol Labetalol The metabolism of Labetalol can be decreased when combined with Temsirolimus.
Pimozide Pimozide The metabolism of Temsirolimus can be decreased when combined with Pimozide.
Enalapril Enalapril The risk or severity of angioedema can be increased when Temsirolimus is combined with Enalapril.
Amiodarone Amiodarone The metabolism of Temsirolimus can be decreased when combined with Amiodarone.
Buspirone Buspirone The metabolism of Buspirone can be decreased when combined with Temsirolimus.
Lovastatin Lovastatin The metabolism of Temsirolimus can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The metabolism of Temsirolimus can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac The risk or severity of angioedema can be increased when Diclofenac is combined with Temsirolimus.
Fluoxetine Fluoxetine The metabolism of Fluoxetine can be decreased when combined with Temsirolimus.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Temsirolimus.
Clozapine Clozapine The risk or severity of neutropenia can be increased when Temsirolimus is combined with Clozapine.
Estazolam Estazolam The serum concentration of Estazolam can be increased when it is combined with Temsirolimus.
Idarubicin Idarubicin The risk or severity of adverse effects can be increased when Idarubicin is combined with Temsirolimus.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Temsirolimus.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Temsirolimus.
Clarithromycin Clarithromycin The metabolism of Temsirolimus can be decreased when combined with Clarithromycin.
Benazepril Benazepril The risk or severity of angioedema can be increased when Benazepril is combined with Temsirolimus.
Felodipine Felodipine The metabolism of Temsirolimus can be decreased when combined with Felodipine.
Fosinopril Fosinopril The risk or severity of angioedema can be increased when Fosinopril is combined with Temsirolimus.
Pravastatin Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Temsirolimus.
Quinapril Quinapril The risk or severity of angioedema can be increased when Quinapril is combined with Temsirolimus.
Ramipril Ramipril The risk or severity of angioedema can be increased when Ramipril is combined with Temsirolimus.
Simvastatin Simvastatin The metabolism of Temsirolimus can be decreased when combined with Simvastatin.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Temsirolimus.
Teniposide Injection Teniposide Injection The metabolism of Temsirolimus can be decreased when combined with Teniposide.
Itraconazole Itraconazole The serum concentration of the active metabolites of Temsirolimus can be increased when Temsirolimus is used in combination with Itraconazole.
Lisinopril Lisinopril The risk or severity of angioedema can be increased when Lisinopril is combined with Temsirolimus.
Rifabutin Rifabutin The metabolism of Temsirolimus can be increased when combined with Rifabutin.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Temsirolimus.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Temsirolimus.
Zolpidem Zolpidem The metabolism of Zolpidem can be decreased when combined with Temsirolimus.
Doxazosin Doxazosin The metabolism of Temsirolimus can be decreased when combined with Doxazosin.
Isradipine Isradipine The metabolism of Temsirolimus can be decreased when combined with Isradipine.
Omeprazole Omeprazole The metabolism of Temsirolimus can be increased when combined with Omeprazole.
Cisapride Cisapride The serum concentration of Cisapride can be increased when it is combined with Temsirolimus.
Fluvastatin Fluvastatin The metabolism of Temsirolimus can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Temsirolimus.
Famciclovir Famciclovir The metabolism of Temsirolimus can be decreased when combined with Famciclovir.
Fluvoxamine Fluvoxamine The metabolism of Temsirolimus can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Temsirolimus can be decreased when combined with Nefazodone.
Losartan Losartan The metabolism of Temsirolimus can be decreased when combined with Losartan.
Tramadol Tramadol The metabolism of Temsirolimus can be decreased when combined with Tramadol.
Vinorelbine Injection Vinorelbine Injection The risk or severity of adverse effects can be increased when Vinorelbine is combined with Temsirolimus.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Temsirolimus.
Moexipril Moexipril The risk or severity of angioedema can be increased when Moexipril is combined with Temsirolimus.
Lansoprazole Lansoprazole The metabolism of Temsirolimus can be increased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Temsirolimus can be increased when combined with Ifosfamide.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Temsirolimus.
Nicardipine Nicardipine The metabolism of Temsirolimus can be decreased when combined with Nicardipine.
Ticlopidine Ticlopidine The metabolism of Temsirolimus can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Temsirolimus can be decreased when combined with Saquinavir.
Metformin Metformin The therapeutic efficacy of Metformin can be decreased when used in combination with Temsirolimus.
Dalteparin Injection Dalteparin Injection The risk or severity of bleeding can be increased when Dalteparin is combined with Temsirolimus.
Nisoldipine Nisoldipine The metabolism of Temsirolimus can be decreased when combined with Nisoldipine.
Acarbose Acarbose The therapeutic efficacy of Acarbose can be decreased when used in combination with Temsirolimus.
Glimepiride Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with Temsirolimus.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Temsirolimus can be increased when it is combined with Gemcitabine.
Indinavir Indinavir The metabolism of Temsirolimus can be decreased when combined with Indinavir.
Ritonavir Ritonavir The serum concentration of Temsirolimus can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Temsirolimus can be decreased when combined with Docetaxel.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Temsirolimus.
Zafirlukast Zafirlukast The metabolism of Temsirolimus can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Temsirolimus can be decreased when combined with Mirtazapine.
Trandolapril Trandolapril The risk or severity of angioedema can be increased when Trandolapril is combined with Temsirolimus.
Topiramate Topiramate The metabolism of Temsirolimus can be increased when combined with Topiramate.
Valsartan Valsartan The risk or severity of angioedema can be increased when Valsartan is combined with Temsirolimus.
Insulin Lispro Injection Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Temsirolimus.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Temsirolimus.
Nelfinavir Nelfinavir The metabolism of Temsirolimus can be decreased when combined with Nelfinavir.
Fexofenadine Fexofenadine The serum concentration of Temsirolimus can be increased when it is combined with Fexofenadine.
Azithromycin Azithromycin The metabolism of Temsirolimus can be decreased when combined with Azithromycin.
Carvedilol Carvedilol The serum concentration of Temsirolimus can be increased when it is combined with Carvedilol.
Flutamide Flutamide The metabolism of Temsirolimus can be decreased when combined with Flutamide.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Temsirolimus.
Bicalutamide Bicalutamide The metabolism of Temsirolimus can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Sertraline can be decreased when combined with Temsirolimus.
Propafenone Propafenone The serum concentration of Temsirolimus can be increased when it is combined with Propafenone.
Raloxifene Raloxifene The metabolism of Raloxifene can be decreased when combined with Temsirolimus.
Irbesartan Irbesartan The metabolism of Temsirolimus can be decreased when combined with Irbesartan.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Temsirolimus.
Finasteride Finasteride The metabolism of Temsirolimus can be decreased when combined with Finasteride.
Quetiapine Quetiapine The metabolism of Temsirolimus can be decreased when combined with Quetiapine.
Paroxetine Paroxetine The metabolism of Temsirolimus can be decreased when combined with Paroxetine.
Citalopram Citalopram The metabolism of Temsirolimus can be decreased when combined with Citalopram.
Capecitabine Capecitabine The risk or severity of adverse effects can be increased when Capecitabine is combined with Temsirolimus.
Efavirenz Efavirenz The metabolism of Temsirolimus can be increased when combined with Efavirenz.
Sildenafil Sildenafil The serum concentration of Temsirolimus can be increased when it is combined with Sildenafil.
Pioglitazone Pioglitazone The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Temsirolimus.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Temsirolimus.
Celecoxib Celecoxib The metabolism of Celecoxib can be decreased when combined with Temsirolimus.
Rosiglitazone Rosiglitazone The therapeutic efficacy of Rosiglitazone can be decreased when used in combination with Temsirolimus.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Temsirolimus.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Temsirolimus.
Nateglinide Nateglinide The metabolism of Temsirolimus can be decreased when combined with Nateglinide.
Galantamine Galantamine The metabolism of Galantamine can be decreased when combined with Temsirolimus.
Rabeprazole Rabeprazole The metabolism of Temsirolimus can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Temsirolimus can be increased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists