Trimipramine

Generic name: Pronounced as (trye mi' pra meen)
Brand names
  • Surmontil®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 09/15/2018

A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as trimipramine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Children younger than 18 years of age should not normally take trimipramine, but in some cases, a doctor may decide that trimipramine is the best medication to treat a child's condition.

You should know that your mental health may change in unexpected ways when you take trimipramine or other antidepressants even if you are an adult over age 24. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor when you are unable to seek treatment on your own.

Your healthcare provider will want to see you often while you are taking trimipramine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.

The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with trimipramine. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide from the FDA website: http://www.fda.gov/Drugs/DrugSafety/InformationbyDrugClass/UCM096273.

No matter your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.

Trimipramine is used to treat depression. Trimipramine is in a class of medications called tricyclic antidepressants. It works by increasing the amount of certain natural substances in the brain that are needed to maintain mental balance.

Trimipramine comes as a capsule to take by mouth. It is usually taken one to three times a day. Take trimipramine at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take trimipramine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will start you on a low dose of trimipramine and gradually increase your dose.

It may take up to 4 weeks before you feel the benefit of trimipramine. Continue to take trimipramine even if you feel well. Do not stop taking trimipramine without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking trimipramine,

  • tell your doctor and pharmacist if you are allergic to trimipramine, clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), or any other medications, or any of the ingredients in trimipramine capsules. Ask your doctor or pharmacist for a list of the ingredients.

  • tell your doctor if you are taking monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil) selegiline (Eldepryl, Emsam, Zelapar) and tranylcypromine (Parnate) or if you have taken an MAO inhibitor during the past 14 days. Your doctor will probably tell you not to take trimipramine.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: cimetidine (Tagamet); decongestants; guanethidine (Ismelin); ipratropium (Atrovent); medications for irritable bowel disease, motion sickness, Parkinson's disease, ulcers, or urinary problems; medications for irregular heartbeats such as quinidine (Quinidex), flecainide (Tambocor), and propafenone (Rythmol); other antidepressants; and selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine (Prozac, Sarafem), paroxetine (Paxil), and sertraline (Zoloft). Tell your doctor or pharmacist if you have stopped taking fluoxetine (Prozac, Sarafem) in the past 5 weeks. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have recently had a heart attack. Your doctor will probably tell you not to take trimipramine.

  • tell your doctor if you have or have ever had an enlargement of the prostate (a male reproductive gland), difficulty urinating, thyroid disease, seizures, or heart, kidney, or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking trimipramine, call your doctor.

  • talk to your doctor about the risks and benefits of taking trimipramine if you are 65 years of age or older. Older adults should not usually take trimipramine because it is not as safe or effective as other medications that can be used to treat the same condition.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking trimipramine.

  • you should know that trimipramine may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

  • remember that alcohol can add to the drowsiness caused by this medication.

  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Trimipramine may make your skin sensitive to sunlight.

  • you should know that trimipramine may cause angle-closure glaucoma (a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a quick, severe increase in eye pressure which may lead to a loss of vision). Talk to your doctor about having an eye examination before you start taking this medication. If you have nausea, eye pain, changes in vision, such as seeing colored rings around lights, and swelling or redness in or around the eye, call your doctor or get emergency medical treatment right away.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Trimipramine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • nausea

    • vomiting

    • diarrhea

    • stomach pain

    • drowsiness

    • weakness or tiredness

    • excitement or anxiety

    • confusion

    • dizziness

    • headache

    • nightmares

    • dry mouth

    • changes in appetite or weight

    • constipation

    • difficulty urinating

    • frequent urination

    • changes in sex drive or ability

    • excessive sweating

    • ringing in the ears

    • pain, burning, or tingling in the hands or feet

  • Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS sections, call your doctor immediately or get emergency medical treatment:

    • jaw, neck, and back muscle spasms

    • slow or difficult speech

    • shuffling walk

    • uncontrollable shaking of a part of the body

    • fever and sore throat

    • difficulty breathing or swallowing

    • rash

    • yellowing of the skin or eyes

    • seizures

    • seeing things or hearing voices that do not exist (hallucinating)

    • chest pain

    • pounding or irregular heartbeat

  • Trimipramine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Moxifloxacin.
Repaglinide Repaglinide Trimipramine may decrease the hypoglycemic activities of Repaglinide.
Montelukast Montelukast The metabolism of Trimipramine can be decreased when combined with Montelukast.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection Trimipramine may decrease the hypoglycemic activities of Insulin glargine.
Leflunomide Leflunomide The metabolism of Trimipramine can be decreased when combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Trimipramine can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Trimipramine can be decreased when combined with Nevirapine.
Dolasetron Dolasetron The metabolism of Dolasetron can be decreased when combined with Trimipramine.
Anagrelide Anagrelide The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Anagrelide.
Candesartan Candesartan The metabolism of Trimipramine can be decreased when combined with Candesartan.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Trimipramine.
Clopidogrel Clopidogrel The metabolism of Trimipramine can be decreased when combined with Clopidogrel.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Trimipramine is combined with Diphenoxylate.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Erythromycin can be increased when it is combined with Trimipramine.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The serum concentration of Trimipramine can be increased when it is combined with Conjugated estrogens.
Fenofibrate Fenofibrate The metabolism of Trimipramine can be decreased when combined with Fenofibrate.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Trimipramine is combined with Guanfacine.
Methylergonovine Methylergonovine The risk or severity of hypertension can be increased when Methylergometrine is combined with Trimipramine.
Miglitol Miglitol Trimipramine may decrease the hypoglycemic activities of Miglitol.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Trimipramine is combined with Naratriptan.
Olsalazine Olsalazine The risk or severity of hypertension can be increased when Trimipramine is combined with Olsalazine.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Trimipramine.
Penbutolol Penbutolol The metabolism of Acebutolol can be decreased when combined with Trimipramine.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Trimipramine.
Ranitidine Ranitidine The metabolism of Trimipramine can be decreased when combined with Ranitidine.
Reserpine Reserpine The serum concentration of Trimipramine can be increased when it is combined with Reserpine.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Trimipramine is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Trimipramine.
Tacrolimus Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Trimipramine.
Tizanidine Tizanidine The risk or severity of hypertension can be increased when Trimipramine is combined with Tizanidine.
Zolmitriptan Zolmitriptan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Trimipramine.
Famotidine Injection Famotidine Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Famotidine.
Fluconazole Injection Fluconazole Injection The serum concentration of Trimipramine can be increased when it is combined with Fluconazole.
Foscarnet Injection Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Trimipramine.
Hydromorphone Injection Hydromorphone Injection The metabolism of Trimipramine can be decreased when combined with Hydromorphone.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Levofloxacin.
Meperidine Injection Meperidine Injection The metabolism of Trimipramine can be decreased when combined with Meperidine.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Trimipramine.
Metronidazole Injection Metronidazole Injection The metabolism of Trimipramine can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Trimipramine.
Zidovudine Injection Zidovudine Injection The metabolism of Trimipramine can be decreased when combined with Zidovudine.
Altretamine Altretamine Amphetamine may decrease the sedative and stimulatory activities of Trimipramine.
Cyclosporine Cyclosporine The metabolism of Trimipramine can be decreased when combined with Cyclosporine.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Trimipramine.
Granisetron Granisetron The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Granisetron.
Torsemide Torsemide The metabolism of Trimipramine can be decreased when combined with Torasemide.
Olanzapine Olanzapine Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Olanzapine.
Alosetron Alosetron The metabolism of Alosetron can be decreased when combined with Trimipramine.
Dofetilide Dofetilide The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Dofetilide.
Entacapone Entacapone The metabolism of Trimipramine can be decreased when combined with Entacapone.
Eprosartan Eprosartan Trimipramine may decrease the antihypertensive activities of Eprosartan.
Hydroxychloroquine Hydroxychloroquine The metabolism of Hydroxychloroquine can be decreased when combined with Trimipramine.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Trimipramine.
Oxcarbazepine Oxcarbazepine The metabolism of Oxcarbazepine can be decreased when combined with Trimipramine.
Pantoprazole Pantoprazole The metabolism of Trimipramine can be decreased when combined with Pantoprazole.
Telmisartan Telmisartan The metabolism of Telmisartan can be decreased when combined with Trimipramine.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Trimipramine is combined with Zaleplon.
Anakinra Anakinra The metabolism of Trimipramine can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Trimipramine is combined with Desloratadine.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Trimipramine.
Etanercept Injection Etanercept Injection The metabolism of Trimipramine can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Modafinil Modafinil The metabolism of Trimipramine can be decreased when combined with Modafinil.
Perindopril Perindopril Trimipramine may decrease the antihypertensive activities of Perindopril.
Tenofovir Tenofovir The serum concentration of Trimipramine can be increased when it is combined with Tenofovir.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Trimipramine is combined with Choline magnesium trisalicylate.
Sirolimus Sirolimus The serum concentration of Trimipramine can be increased when it is combined with Sirolimus.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Trimipramine is combined with Dutasteride.
Epinephrine Injection Epinephrine Injection The metabolism of Trimipramine can be decreased when combined with Epinephrine.
Eplerenone Eplerenone Trimipramine may decrease the antihypertensive activities of Eplerenone.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Trimipramine is combined with Escitalopram.
Olmesartan Olmesartan Trimipramine may decrease the antihypertensive activities of Olmesartan.
Zonisamide Zonisamide The serum concentration of Zonisamide can be increased when it is combined with Trimipramine.
Adalimumab Injection Adalimumab Injection The metabolism of Trimipramine can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Atomoxetine Atomoxetine The metabolism of Trimipramine can be decreased when combined with Atomoxetine.
Dexmethylphenidate Dexmethylphenidate The serum concentration of Trimipramine can be increased when it is combined with Dexmethylphenidate.
Atazanavir Atazanavir The metabolism of Trimipramine can be decreased when combined with Atazanavir.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Trimipramine.
Eletriptan Eletriptan The metabolism of Trimipramine can be decreased when combined with Eletriptan.
Mefloquine Mefloquine The metabolism of Trimipramine can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Trimipramine.
Vardenafil Vardenafil The serum concentration of Vardenafil can be increased when it is combined with Trimipramine.
Alfuzosin Alfuzosin Alfuzosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Aprepitant Aprepitant The metabolism of Trimipramine can be decreased when combined with Aprepitant.
Memantine Memantine The metabolism of Trimipramine can be decreased when combined with Memantine.
Tegaserod Tegaserod The metabolism of Trimipramine can be decreased when combined with Tegaserod.
Tadalafil Tadalafil The risk or severity of hypotension, dyspepsia, and headache can be increased when Trimipramine is combined with Tadalafil.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Trimipramine is combined with Frovatriptan.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Gemifloxacin.
Progesterone Progesterone The metabolism of Trimipramine can be decreased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Trimipramine.
Infliximab Injection Infliximab Injection The metabolism of Trimipramine can be increased when combined with Infliximab.
Oxandrolone Oxandrolone The metabolism of Trimipramine can be decreased when combined with Oxandrolone.
Protriptyline Protriptyline The metabolism of Trimipramine can be decreased when combined with Protriptyline.
Rifaximin Rifaximin The metabolism of Trimipramine can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Trimipramine can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Trimipramine can be increased when combined with Norethisterone.
Trospium Trospium The metabolism of Trospium can be decreased when combined with Trimipramine.
Bosentan Bosentan The metabolism of Trimipramine can be decreased when combined with Bosentan.
Cinacalcet Cinacalcet The metabolism of Trimipramine can be decreased when combined with Cinacalcet.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Trimipramine.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Trimipramine is combined with Eszopiclone.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection Trimipramine may decrease the hypoglycemic activities of Insulin aspart.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Trimipramine.
Voriconazole Voriconazole The metabolism of Trimipramine can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine Amphetamine may decrease the sedative and stimulatory activities of Trimipramine.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Trimipramine can be decreased when combined with Peginterferon alfa-2b.
Pramlintide Injection Pramlintide Injection Trimipramine may decrease the hypoglycemic activities of Pramlintide.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Trimipramine.
Exenatide Injection Exenatide Injection Trimipramine may decrease the hypoglycemic activities of Exenatide.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Trimipramine.
Isocarboxazid Isocarboxazid Trimipramine may increase the serotonergic activities of Isocarboxazid.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Trimipramine.
Darifenacin Darifenacin The metabolism of Trimipramine can be decreased when combined with Darifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Trimipramine is combined with Fentanyl.
Pregabalin Pregabalin The therapeutic efficacy of Trimipramine can be increased when used in combination with Pregabalin.
Phenylephrine Phenylephrine Trimipramine may increase the vasopressor activities of Phenylephrine.
Tipranavir Tipranavir The metabolism of Trimipramine can be decreased when combined with Tipranavir.
Felbamate Felbamate The metabolism of Trimipramine can be decreased when combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection Trimipramine may decrease the hypoglycemic activities of Insulin detemir.
Ranolazine Ranolazine The serum concentration of Trimipramine can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Trimipramine can be increased when combined with Abatacept.
Rasagiline Rasagiline Rasagiline may increase the serotonergic activities of Trimipramine.
Imatinib Imatinib The metabolism of Trimipramine can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin Trimipramine may decrease the hypoglycemic activities of Sitagliptin.
Gefitinib Gefitinib The metabolism of Trimipramine can be decreased when combined with Gefitinib.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Salbutamol.
Paliperidone Paliperidone Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Paliperidone.
Bortezomib Bortezomib The metabolism of Trimipramine can be decreased when combined with Bortezomib.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection Trimipramine may decrease the hypoglycemic activities of Insulin glulisine.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Oxaliplatin.
Posaconazole Posaconazole The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Posaconazole.
Primaquine Primaquine The metabolism of Trimipramine can be decreased when combined with Primaquine.
Aliskiren Aliskiren Trimipramine may decrease the antihypertensive activities of Aliskiren.
Bismuth Subsalicylate Bismuth Subsalicylate Trimipramine may increase the neurotoxic activities of Bismuth subsalicylate.
Dimenhydrinate Dimenhydrinate The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Dimenhydrinate.
Lisdexamfetamine Lisdexamfetamine Lisdexamfetamine may decrease the sedative and stimulatory activities of Trimipramine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Trimipramine.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Vorinostat.
Sorafenib Sorafenib The serum concentration of Trimipramine can be increased when it is combined with Sorafenib.
Sunitinib Sunitinib Trimipramine may decrease the hypoglycemic activities of Sunitinib.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Trimipramine.
Lapatinib Lapatinib The serum concentration of Lapatinib can be increased when it is combined with Trimipramine.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Trimipramine is combined with Levocetirizine.
Dasatinib Dasatinib The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Dasatinib.
Mexiletine Mexiletine The metabolism of Trimipramine can be decreased when combined with Mexiletine.
Armodafinil Armodafinil The metabolism of Trimipramine can be decreased when combined with Armodafinil.
Temsirolimus Temsirolimus The serum concentration of Trimipramine can be increased when it is combined with Temsirolimus.
Nilotinib Nilotinib The metabolism of Trimipramine can be decreased when combined with Nilotinib.
Toremifene Toremifene The serum concentration of Toremifene can be increased when it is combined with Trimipramine.
Bexarotene Bexarotene The metabolism of Trimipramine can be decreased when combined with Bexarotene.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Trimipramine can be decreased when combined with Chloramphenicol.
Desmopressin Desmopressin The risk or severity of hyponatremia and water intoxication can be increased when Trimipramine is combined with Desmopressin.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Trimipramine.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Trimipramine.
Etravirine Etravirine The serum concentration of Trimipramine can be decreased when it is combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Arsenic trioxide is combined with Trimipramine.
Desvenlafaxine Desvenlafaxine The metabolism of Desvenlafaxine can be decreased when combined with Trimipramine.
Cevimeline Cevimeline The metabolism of Trimipramine can be decreased when combined with Cevimeline.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Trimipramine.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Trimipramine.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Trimipramine.
Certolizumab Injection Certolizumab Injection The metabolism of Trimipramine can be increased when combined with Certolizumab pegol.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Trimipramine.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Trimipramine.
Silodosin Silodosin Silodosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Trimipramine.
Naltrexone Injection Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Trimipramine.
Milnacipran Milnacipran The risk or severity of adverse effects can be increased when Trimipramine is combined with Milnacipran.
Dexlansoprazole Dexlansoprazole The metabolism of Trimipramine can be decreased when combined with Dexlansoprazole.
Sodium Phosphate Sodium Phosphate The risk or severity of seizure can be increased when Trimipramine is combined with Sodium phosphate, monobasic.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Trimipramine.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Degarelix.
Betaxolol Betaxolol The metabolism of Betaxolol can be decreased when combined with Trimipramine.
Iloperidone Iloperidone Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Iloperidone.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Trimipramine.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Trimipramine.
Everolimus Everolimus The metabolism of Trimipramine can be decreased when combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Trimipramine can be increased when it is combined with Tolvaptan.
Dronedarone Dronedarone Dronedarone may increase the QTc-prolonging activities of Trimipramine.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Trimipramine.
Palonosetron Injection Palonosetron Injection The metabolism of Trimipramine can be decreased when combined with Palonosetron.
Saxagliptin Saxagliptin Trimipramine may decrease the hypoglycemic activities of Saxagliptin.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Telavancin.
Romidepsin Injection Romidepsin Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Romidepsin.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Trimipramine.
Golimumab Injection Golimumab Injection The metabolism of Trimipramine can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be decreased when combined with Trimipramine.
Asenapine Asenapine Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Trimipramine is combined with Vigabatrin.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Trimipramine.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Trimipramine.
Liraglutide Injection Liraglutide Injection Trimipramine may decrease the hypoglycemic activities of Liraglutide.
Tocilizumab Injection Tocilizumab Injection The metabolism of Trimipramine can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine The risk or severity of seizure can be increased when Trimipramine is combined with Dalfampridine.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Eribulin.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Trimipramine.
Cabazitaxel Injection Cabazitaxel Injection The serum concentration of Trimipramine can be increased when it is combined with Cabazitaxel.
Lurasidone Lurasidone Trimipramine may increase the hypotensive activities of Lurasidone.
Acetaminophen Injection Acetaminophen Injection The metabolism of Trimipramine can be decreased when combined with Acetaminophen.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Trimipramine.
Terbutaline Injection Terbutaline Injection The risk or severity of hypertension can be increased when Trimipramine is combined with Terbutaline.
Linagliptin Linagliptin The serum concentration of Linagliptin can be increased when it is combined with Trimipramine.
Rilpivirine Rilpivirine The metabolism of Rilpivirine can be decreased when combined with Trimipramine.
Telaprevir Telaprevir The serum concentration of Trimipramine can be increased when it is combined with Glecaprevir.
Potassium Iodide Potassium Iodide The risk or severity of Cardiac Arrhythmia can be increased when Potassium Iodide is combined with Trimipramine.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Trimipramine can be decreased when combined with Cyclophosphamide.
Abiraterone Abiraterone The metabolism of Trimipramine can be decreased when combined with Abiraterone.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Triptorelin.
Rivaroxaban Rivaroxaban The serum concentration of Trimipramine can be increased when it is combined with Rivaroxaban.
Ticagrelor Ticagrelor The serum concentration of Trimipramine can be increased when it is combined with Ticagrelor.
Vandetanib Vandetanib The serum concentration of Vandetanib can be increased when it is combined with Trimipramine.
Clobazam Clobazam The metabolism of Trimipramine can be decreased when combined with Clobazam.
Vemurafenib Vemurafenib The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Trimipramine.
Vismodegib Vismodegib The metabolism of Trimipramine can be decreased when combined with Vismodegib.
Ivacaftor Ivacaftor The serum concentration of Trimipramine can be increased when it is combined with Ivacaftor.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Trimipramine.
Crizotinib Crizotinib The serum concentration of Crizotinib can be increased when it is combined with Trimipramine.
Cabergoline Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Trimipramine.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Trimipramine.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Trimipramine is combined with Tiagabine.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Trimipramine can be increased when it is combined with Carfilzomib.
Enzalutamide Enzalutamide The serum concentration of Trimipramine can be increased when it is combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Trimipramine.
Regorafenib Regorafenib The serum concentration of Trimipramine can be increased when it is combined with Regorafenib.
Lorcaserin Lorcaserin Trimipramine may decrease the hypoglycemic activities of Mecasermin.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Trimipramine.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Bedaquiline.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Trimipramine.
Ponatinib Ponatinib The serum concentration of Ponatinib can be increased when it is combined with Trimipramine.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Trimipramine is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Trimipramine can be increased when it is combined with Trastuzumab emtansine.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Trimipramine.
Canagliflozin Canagliflozin The serum concentration of Canagliflozin can be increased when it is combined with Trimipramine.
Dabrafenib Dabrafenib The metabolism of Trimipramine can be increased when combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Trimipramine.
Dolutegravir Dolutegravir The serum concentration of Trimipramine can be increased when it is combined with Dolutegravir.
Afatinib Afatinib The serum concentration of Trimipramine can be increased when it is combined with Afatinib.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Trimipramine.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Trimipramine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Trimipramine.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Trimipramine.
Lomitapide Lomitapide The serum concentration of Trimipramine can be increased when it is combined with Lomitapide.
Avanafil Avanafil The risk or severity of hypotension, dyspepsia, and headache can be increased when Avanafil is combined with Trimipramine.
Ketorolac Injection Ketorolac Injection The metabolism of Trimipramine can be decreased when combined with Ketorolac.
Simeprevir Simeprevir The serum concentration of Trimipramine can be increased when it is combined with Simeprevir.
Sofosbuvir Sofosbuvir The serum concentration of Trimipramine can be increased when it is combined with Sofosbuvir.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Trimipramine.
Apremilast Apremilast The metabolism of Trimipramine can be increased when combined with Apremilast.
Droxidopa Droxidopa Trimipramine may increase the vasopressor activities of Droxidopa.
Ceritinib Ceritinib The metabolism of Trimipramine can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Trimipramine can be increased when combined with Siltuximab.
Albiglutide Injection Albiglutide Injection Trimipramine may decrease the hypoglycemic activities of Albiglutide.
Eslicarbazepine Eslicarbazepine The metabolism of Eslicarbazepine can be decreased when combined with Trimipramine.
Belinostat Injection Belinostat Injection The serum concentration of Trimipramine can be increased when it is combined with Belinostat.
Idelalisib Idelalisib The serum concentration of Trimipramine can be increased when it is combined with Idelalisib.
Testosterone Injection Testosterone Injection The metabolism of Trimipramine can be decreased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Trimipramine can be decreased when combined with Oritavancin.
Empagliflozin Empagliflozin Trimipramine may decrease the hypoglycemic activities of Empagliflozin.
Vorapaxar Vorapaxar The serum concentration of Trimipramine can be increased when it is combined with Vorapaxar.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Trimipramine.
Suvorexant Suvorexant Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Dulaglutide Injection Dulaglutide Injection Trimipramine may decrease the hypoglycemic activities of Dulaglutide.
Edoxaban Edoxaban The serum concentration of Trimipramine can be increased when it is combined with Edoxaban.
Olaparib Olaparib The metabolism of Trimipramine can be increased when combined with Olaparib.
Methamphetamine Methamphetamine Metamfetamine may decrease the sedative and stimulatory activities of Trimipramine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Trimipramine is combined with Tasimelteon.
Riociguat Riociguat Trimipramine may decrease the antihypertensive activities of Riociguat.
Nintedanib Nintedanib The serum concentration of Trimipramine can be increased when it is combined with Nintedanib.
Secukinumab Injection Secukinumab Injection The metabolism of Trimipramine can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Risperidone.
Palbociclib Palbociclib The serum concentration of Trimipramine can be increased when it is combined with Palbociclib.
Insulin Human Inhalation Insulin Human Inhalation Trimipramine may decrease the hypoglycemic activities of Insulin human.
Lenvatinib Lenvatinib The metabolism of Trimipramine can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Trimipramine can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Trimipramine can be decreased when combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The serum concentration of Trimipramine can be increased when it is combined with Haloperidol.
Ivabradine Ivabradine The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Ivabradine.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Trimipramine can be increased when it is combined with Isavuconazonium.
Macitentan Macitentan Trimipramine may decrease the antihypertensive activities of Macitentan.
Flibanserin Flibanserin The serum concentration of Flibanserin can be increased when it is combined with Trimipramine.
Rolapitant Rolapitant The metabolism of Trimipramine can be decreased when combined with Rolapitant.
Daclatasvir Daclatasvir The serum concentration of Trimipramine can be increased when it is combined with Daclatasvir.
Brexpiprazole Brexpiprazole Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Ziprasidone.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Trimipramine.
Eluxadoline Eluxadoline The risk or severity of serotonin syndrome can be increased when Trimipramine is combined with Eluxadoline.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection Trimipramine may decrease the hypoglycemic activities of Insulin degludec.
Cobimetinib Cobimetinib The serum concentration of Trimipramine can be increased when it is combined with Cobimetinib.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Trimipramine.
Osimertinib Osimertinib The serum concentration of Trimipramine can be increased when it is combined with Osimertinib.
Rifapentine Rifapentine The metabolism of Trimipramine can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Trimipramine.
Dexamethasone Injection Dexamethasone Injection The metabolism of Trimipramine can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Trimipramine.
Venetoclax Venetoclax The serum concentration of Trimipramine can be increased when it is combined with Venetoclax.
Cobicistat Cobicistat The serum concentration of Trimipramine can be increased when it is combined with Cobicistat.
Midodrine Midodrine Midodrine may increase the vasopressor activities of Trimipramine.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Trimipramine.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Trimipramine is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Trimipramine.
Furosemide Injection Furosemide Injection Trimipramine may decrease the antihypertensive activities of Furosemide.
Rucaparib Rucaparib The metabolism of Trimipramine can be decreased when combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection Trimipramine may decrease the hypoglycemic activities of Lixisenatide.
Ribociclib Ribociclib The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Ribociclib.
Doxepin (Insomnia) Doxepin (Insomnia) Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Doxepin.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Trimipramine.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Trimipramine.
Safinamide Safinamide The metabolism of Safinamide can be decreased when combined with Trimipramine.
Midostaurin Midostaurin The metabolism of Trimipramine can be decreased when combined with Midostaurin.
Neratinib Neratinib The serum concentration of Trimipramine can be increased when it is combined with Neratinib.
Enasidenib Enasidenib The metabolism of Trimipramine can be decreased when combined with Enasidenib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Trimipramine can be increased when it is combined with Inotuzumab ozogamicin.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Trimipramine can be increased when combined with Fosaprepitant.
Copanlisib Injection Copanlisib Injection The serum concentration of Trimipramine can be increased when it is combined with Copanlisib.
Delafloxacin Delafloxacin The metabolism of Trimipramine can be increased when combined with Delafloxacin.
Betrixaban Betrixaban The serum concentration of Trimipramine can be increased when it is combined with Betrixaban.
Letermovir Letermovir The metabolism of Letermovir can be decreased when combined with Trimipramine.
Semaglutide Injection Semaglutide Injection Trimipramine may decrease the hypoglycemic activities of Semaglutide.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Trimipramine.
Ertugliflozin Ertugliflozin Trimipramine may decrease the hypoglycemic activities of Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide The serum concentration of Trimipramine can be decreased when it is combined with Apalutamide.
Fostamatinib Fostamatinib The risk or severity of hypotension, dyspepsia, and headache can be increased when Fostamatinib is combined with Trimipramine.
Avatrombopag Avatrombopag The metabolism of Trimipramine can be increased when combined with Avatrombopag.
Baricitinib Baricitinib The serum concentration of Trimipramine can be increased when it is combined with Baricitinib.
Lofexidine Lofexidine The therapeutic efficacy of Trimipramine can be increased when used in combination with Lofexidine.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Trimipramine.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Trimipramine.
Ivosidenib Ivosidenib The serum concentration of Ivosidenib can be increased when it is combined with Trimipramine.
Lusutrombopag Lusutrombopag The serum concentration of Trimipramine can be increased when it is combined with Lusutrombopag.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Trimipramine.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Trimipramine.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Trimipramine.
Dacomitinib Dacomitinib The metabolism of Dacomitinib can be decreased when combined with Trimipramine.
Duvelisib Duvelisib The serum concentration of Trimipramine can be increased when it is combined with Duvelisib.
Omadacycline Omadacycline The serum concentration of Trimipramine can be increased when it is combined with Omadacycline.
Sarecycline Sarecycline The serum concentration of Trimipramine can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The metabolism of Stiripentol can be decreased when combined with Trimipramine.
Talazoparib Talazoparib The serum concentration of Trimipramine can be increased when it is combined with Talazoparib.
Gilteritinib Gilteritinib The therapeutic efficacy of Trimipramine can be decreased when used in combination with Gilteritinib.
Glasdegib Glasdegib The serum concentration of Glasdegib can be increased when it is combined with Trimipramine.
Lorlatinib Lorlatinib The metabolism of Trimipramine can be increased when combined with Lorlatinib.
Larotrectinib Larotrectinib The serum concentration of Trimipramine can be increased when it is combined with Larotrectinib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection Trimipramine may increase the neurotoxic activities of Paclitaxel.
Rifamycin Rifamycin The serum concentration of Trimipramine can be increased when it is combined with Rifamycin.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Trimipramine can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Trimipramine.
Erdafitinib Erdafitinib The serum concentration of Erdafitinib can be increased when it is combined with Trimipramine.
Esomeprazole Injection Esomeprazole Injection The metabolism of Trimipramine can be decreased when combined with Esomeprazole.
Alpelisib Alpelisib The serum concentration of Trimipramine can be decreased when it is combined with Alpelisib.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Trimipramine is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Trimipramine.
Darolutamide Darolutamide The serum concentration of Trimipramine can be increased when it is combined with Darolutamide.
Triclabendazole Triclabendazole The metabolism of Trimipramine can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Entrectinib.
Istradefylline Istradefylline The serum concentration of Istradefylline can be increased when it is combined with Trimipramine.
Pitolisant Pitolisant The therapeutic efficacy of Pitolisant can be decreased when used in combination with Trimipramine.
Fedratinib Fedratinib The serum concentration of Trimipramine can be increased when it is combined with Fedratinib.
Lefamulin Lefamulin Lefamulin may increase the QTc-prolonging activities of Trimipramine.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Trimipramine.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Trimipramine.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Trimipramine can be increased when it is combined with Enfortumab vedotin.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Trimipramine.
Voxelotor Voxelotor The metabolism of Voxelotor can be decreased when combined with Trimipramine.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Trimipramine.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Trimipramine is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Trimipramine is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Trimipramine can be increased when it is combined with Ubrogepant.
Tazemetostat Tazemetostat The serum concentration of Trimipramine can be increased when it is combined with Tazemetostat.
Cenobamate Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Trimipramine.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Trimipramine.
Rimegepant Rimegepant The serum concentration of Trimipramine can be increased when it is combined with Rimegepant.
Tucatinib Tucatinib The serum concentration of Trimipramine can be increased when it is combined with Tucatinib.
Remdesivir Injection Remdesivir Injection The serum concentration of Trimipramine can be increased when it is combined with Remdesivir.
Ripretinib Ripretinib The serum concentration of Trimipramine can be increased when it is combined with Ripretinib.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Trimipramine is combined with Selpercatinib.
Capmatinib Capmatinib The serum concentration of Trimipramine can be increased when it is combined with Capmatinib.
Lemborexant Lemborexant The serum concentration of Trimipramine can be decreased when it is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Trimipramine.
Fostemsavir Fostemsavir The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Fostemsavir.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Trimipramine.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Trimipramine can be increased when it is combined with Belantamab mafodotin.
Pralsetinib Pralsetinib The serum concentration of Trimipramine can be increased when it is combined with Pralsetinib.
Opicapone Opicapone The metabolism of Trimipramine can be increased when combined with Opicapone.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Trimipramine can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Trimipramine is combined with Naxitamab.
Relugolix Relugolix The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Relugolix.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Trimipramine is combined with Viloxazine.
Theophylline Theophylline The metabolism of Trimipramine can be decreased when combined with Theophylline.
Fenoprofen Fenoprofen The risk or severity of hypertension can be increased when Fenoprofen is combined with Trimipramine.
Indomethacin Indomethacin The metabolism of Trimipramine can be decreased when combined with Indomethacin.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be decreased when combined with Trimipramine.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Trimipramine.
Tolmetin Tolmetin The risk or severity of hypertension can be increased when Tolmetin is combined with Trimipramine.
Sulindac Sulindac The risk or severity of hypertension can be increased when Sulindac is combined with Trimipramine.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Trimipramine.
Hydroxyurea Hydroxyurea The metabolism of Trimipramine can be decreased when combined with Hydroxyurea.
Floxuridine Floxuridine The metabolism of Trimipramine can be decreased when combined with Floxuridine.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Trimipramine.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Trimipramine.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Trimipramine is combined with Levorphanol.
Primidone Primidone The metabolism of Trimipramine can be decreased when combined with Primidone.
Methsuximide Methsuximide The metabolism of Methsuximide can be decreased when combined with Trimipramine.
Diethylpropion Diethylpropion Diethylpropion may decrease the sedative and stimulatory activities of Trimipramine.
Chlorpromazine Chlorpromazine Chlorpromazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Trimipramine.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Trimipramine is combined with Oxazepam.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Trimipramine.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Trimipramine.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Trimipramine.
Phenoxybenzamine Phenoxybenzamine Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Phenoxybenzamine.
Amantadine Amantadine The risk or severity of serotonin syndrome can be increased when Trimipramine is combined with Amantadine.
Codeine Codeine The metabolism of Trimipramine can be decreased when combined with Codeine.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Trimipramine.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Trimipramine.
Bromocriptine Bromocriptine Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Bromocriptine.
Metaproterenol Metaproterenol The risk or severity of hypertension can be increased when Trimipramine is combined with Orciprenaline.
Tranylcypromine Tranylcypromine The metabolism of Tranylcypromine can be decreased when combined with Trimipramine.
Phenelzine Phenelzine The metabolism of Phenelzine can be decreased when combined with Trimipramine.
Procarbazine Procarbazine Procarbazine may increase the serotonergic activities of Trimipramine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Trimipramine is combined with Ergoloid mesylate.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Trimipramine.
Prochlorperazine Prochlorperazine The serum concentration of Trimipramine can be increased when it is combined with Prochlorperazine.
Thioridazine Thioridazine Thioridazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Trifluoperazine Trifluoperazine Trifluoperazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Dapsone Dapsone The metabolism of Trimipramine can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Trimipramine can be decreased when combined with Sulfadiazine.
Oxycodone Oxycodone The metabolism of Trimipramine can be decreased when combined with Oxycodone.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Trimipramine.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Trimipramine.
Benztropine Benztropine The metabolism of Benzatropine can be decreased when combined with Trimipramine.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Trimipramine.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Trimipramine.
Trihexyphenidyl Trihexyphenidyl Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The serum concentration of Perphenazine can be increased when it is combined with Trimipramine.
Fluphenazine Fluphenazine The serum concentration of Trimipramine can be increased when it is combined with Fluphenazine.
Phentermine Phentermine Phentermine may decrease the sedative and stimulatory activities of Trimipramine.
Methylphenidate Methylphenidate The risk or severity of adverse effects can be increased when Methylphenidate is combined with Trimipramine.
Amoxapine Amoxapine Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Amoxapine.
Sulfasalazine Sulfasalazine The risk or severity of hypertension can be increased when Trimipramine is combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The metabolism of Trimipramine can be increased when combined with Hydrocortisone.
Doxorubicin Doxorubicin The metabolism of Trimipramine can be decreased when combined with Doxorubicin.
Dactinomycin Dactinomycin The serum concentration of Trimipramine can be increased when it is combined with Dactinomycin.
Carbamazepine Carbamazepine The metabolism of Trimipramine can be increased when combined with Carbamazepine.
Molindone Molindone The risk or severity of adverse effects can be increased when Trimipramine is combined with Molindone.
Methyldopa Methyldopa The therapeutic efficacy of Methyldopa can be decreased when used in combination with Trimipramine.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Trimipramine.
Prazosin Prazosin Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Prazosin.
Hydralazine Hydralazine Trimipramine may decrease the antihypertensive activities of Hydralazine.
Cimetidine Cimetidine The metabolism of Trimipramine can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Warfarin can be decreased when combined with Trimipramine.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Trimipramine is combined with Clonazepam.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Trimipramine.
Promethazine Promethazine The serum concentration of Trimipramine can be increased when it is combined with Promethazine.
Meclofenamate Meclofenamate The risk or severity of hypertension can be increased when Trimipramine is combined with Meclofenamic acid.
Digoxin Digoxin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Trimipramine.
Loxapine Loxapine The serum concentration of Trimipramine can be increased when it is combined with Loxapine.
Chloroquine Chloroquine The metabolism of Trimipramine can be decreased when combined with Chloroquine.
Quinine Quinine The metabolism of Trimipramine can be decreased when combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Trimipramine.
Sulfinpyrazone Sulfinpyrazone The metabolism of Trimipramine can be decreased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide Trimipramine may decrease the antihypertensive activities of Chlorothiazide.
Chlorthalidone Chlorthalidone Trimipramine may decrease the antihypertensive activities of Chlorthalidone.
Metolazone Metolazone Trimipramine may decrease the antihypertensive activities of Metolazone.
Clindamycin Injection Clindamycin Injection Trimipramine may increase the neurotoxic activities of Clindamycin.
Secobarbital Secobarbital The metabolism of Trimipramine can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Trimipramine.
Amitriptyline Amitriptyline Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Amitriptyline.
Imipramine Imipramine Imipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Probenecid Probenecid The metabolism of Trimipramine can be decreased when combined with Probenecid.
Quinidine Quinidine Quinidine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Trimipramine.
Isoniazid Isoniazid The metabolism of Trimipramine can be decreased when combined with Isoniazid.
Rifampin Rifampin The serum concentration of Trimipramine can be decreased when it is combined with Rifampicin.
Disopyramide Disopyramide The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Disopyramide.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be decreased when combined with Trimipramine.
Tamoxifen Tamoxifen The metabolism of Trimipramine can be decreased when combined with Tamoxifen.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Trimipramine.
Levothyroxine Levothyroxine The risk or severity of Cardiac Arrhythmia and CNS stimulation can be increased when Levothyroxine is combined with Trimipramine.
Liothyronine Liothyronine The risk or severity of Cardiac Arrhythmia can be increased when Liothyronine is combined with Trimipramine.
Methimazole Methimazole The risk or severity of Cardiac Arrhythmia can be increased when Methimazole is combined with Trimipramine.
Propylthiouracil Propylthiouracil The risk or severity of Cardiac Arrhythmia can be increased when Propylthiouracil is combined with Trimipramine.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Trimipramine.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Trimipramine.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Trimipramine.
Dextromethorphan Dextromethorphan The metabolism of Trimipramine can be decreased when combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Trimipramine is combined with Cyclobenzaprine.
Niacin Niacin The metabolism of Trimipramine can be decreased when combined with Niacin.
Baclofen Baclofen The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Trimipramine.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Trimipramine.
Cyproheptadine Cyproheptadine The risk or severity of adverse effects can be increased when Cyproheptadine is combined with Trimipramine.
Clemastine Clemastine The metabolism of Trimipramine can be decreased when combined with Clemastine.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Trimipramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Trimipramine.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Trimipramine.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Hydrochlorothiazide.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Trimipramine is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The metabolism of Trimipramine can be decreased when combined with Chlorzoxazone.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Trimipramine.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Trimipramine.
Disulfiram Disulfiram The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Disulfiram.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Trimipramine.
Minoxidil Minoxidil Trimipramine may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine Pseudoephedrine Pseudoephedrine may decrease the sedative and stimulatory activities of Trimipramine.
Nortriptyline Nortriptyline Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nortriptyline.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Trimipramine.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Trimipramine.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Trimipramine is combined with Nalbuphine.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Trimipramine.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Trimipramine.
Clomiphene Clomiphene The serum concentration of Trimipramine can be increased when it is combined with Clomifene.
Flavoxate Flavoxate Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Trimipramine.
Colchicine Colchicine The metabolism of Trimipramine can be decreased when combined with Colchicine.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Trimipramine is combined with Acetazolamide.
Calcitonin Salmon Injection Calcitonin Salmon Injection The risk or severity of Cardiac Arrhythmia can be increased when Salmon calcitonin is combined with Trimipramine.
Ketoconazole Ketoconazole The metabolism of Trimipramine can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Trimipramine is combined with Pyrantel.
Thiotepa Injection Thiotepa Injection The metabolism of Trimipramine can be decreased when combined with Thiotepa.
Vincristine Injection Vincristine Injection The serum concentration of Trimipramine can be increased when it is combined with Vincristine.
Captopril Captopril Trimipramine may decrease the antihypertensive activities of Captopril.
Dipyridamole Dipyridamole The risk or severity of hypotension, dyspepsia, and headache can be increased when Dipyridamole is combined with Trimipramine.
Isoxsuprine Isoxsuprine The risk or severity of hypertension can be increased when Trimipramine is combined with Isoxsuprine.
Vinblastine Vinblastine The metabolism of Trimipramine can be decreased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Trimipramine can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Trimipramine.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Trimipramine is combined with Thiothixene.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Trimipramine.
Salsalate Salsalate The risk or severity of hypertension can be increased when Trimipramine is combined with Salsalate.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Trimipramine.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Trimipramine.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Trimipramine is combined with Triazolam.
Dicyclomine Dicyclomine Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim Trimethoprim The metabolism of Trimipramine can be decreased when combined with Trimethoprim.
Diltiazem Diltiazem The metabolism of Diltiazem can be decreased when combined with Trimipramine.
Nifedipine Nifedipine The metabolism of Nifedipine can be decreased when combined with Trimipramine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Trimipramine.
Verapamil Verapamil Verapamil may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Atenolol Atenolol The metabolism of Atenolol can be decreased when combined with Trimipramine.
Pindolol Pindolol The metabolism of Pindolol can be decreased when combined with Trimipramine.
Cisplatin Injection Cisplatin Injection The metabolism of Trimipramine can be decreased when combined with Cisplatin.
Diflunisal Diflunisal The risk or severity of hypertension can be increased when Trimipramine is combined with Diflunisal.
Piroxicam Piroxicam The metabolism of Trimipramine can be decreased when combined with Piroxicam.
Etoposide Etoposide The serum concentration of Trimipramine can be increased when it is combined with Etoposide.
Glyburide Glyburide The metabolism of Trimipramine can be decreased when combined with Glyburide.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Trimipramine.
Indapamide Indapamide The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Indapamide.
Pentoxifylline Pentoxifylline The risk or severity of hypotension, dyspepsia, and headache can be increased when Pentoxifylline is combined with Trimipramine.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Trimipramine.
Labetalol Labetalol Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Labetalol.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Leuprolide.
Gemfibrozil Gemfibrozil The metabolism of Trimipramine can be decreased when combined with Gemfibrozil.
Guanabenz Guanabenz The risk or severity of hypertension can be increased when Trimipramine is combined with Guanabenz.
Ketoprofen Ketoprofen The risk or severity of hypertension can be increased when Trimipramine is combined with Ketoprofen.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Trimipramine.
Enalapril Enalapril Trimipramine may decrease the antihypertensive activities of Enalapril.
Flurbiprofen Flurbiprofen The metabolism of Trimipramine can be decreased when combined with Flurbiprofen.
Amiodarone Amiodarone The serum concentration of Trimipramine can be increased when it is combined with Amiodarone.
Buspirone Buspirone The metabolism of Trimipramine can be decreased when combined with Buspirone.
Lovastatin Lovastatin The metabolism of Trimipramine can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Ciprofloxacin.
Mesalamine Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Trimipramine.
Diclofenac Diclofenac The metabolism of Trimipramine can be decreased when combined with Diclofenac.
Fluoxetine Fluoxetine The serum concentration of Trimipramine can be increased when it is combined with Fluoxetine.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Nimodipine.
Clozapine Clozapine Clozapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Trimipramine is combined with Estazolam.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Trimipramine.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Ofloxacin.
Didanosine Didanosine Trimipramine may increase the neurotoxic activities of Didanosine.
Clarithromycin Clarithromycin The serum concentration of Clarithromycin can be increased when it is combined with Trimipramine.
Benazepril Benazepril Trimipramine may decrease the antihypertensive activities of Benazepril.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Trimipramine.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Trimipramine.
Fosinopril Fosinopril Trimipramine may decrease the antihypertensive activities of Fosinopril.
Nabumetone Nabumetone The metabolism of Trimipramine can be decreased when combined with Nabumetone.
Pravastatin Pravastatin The serum concentration of Trimipramine can be increased when it is combined with Pravastatin.
Quinapril Quinapril Trimipramine may decrease the antihypertensive activities of Quinapril.
Ramipril Ramipril Trimipramine may decrease the antihypertensive activities of Ramipril.
Simvastatin Simvastatin The serum concentration of Trimipramine can be increased when it is combined with Simvastatin.
Amlodipine Amlodipine The risk or severity of hypotension can be increased when Trimipramine is combined with Amlodipine.
Teniposide Injection Teniposide Injection The metabolism of Trimipramine can be decreased when combined with Teniposide.
Itraconazole Itraconazole The serum concentration of Itraconazole can be increased when it is combined with Trimipramine.
Lisinopril Lisinopril Trimipramine may decrease the antihypertensive activities of Lisinopril.
Oxaprozin Oxaprozin The risk or severity of hypertension can be increased when Trimipramine is combined with Oxaprozin.
Atovaquone Atovaquone The metabolism of Trimipramine can be decreased when combined with Atovaquone.
Rifabutin Rifabutin The metabolism of Trimipramine can be increased when combined with Rifabutin.
Sotalol Sotalol The metabolism of Trimipramine can be decreased when combined with Sotalol.
Bisoprolol Bisoprolol Trimipramine may increase the orthostatic hypotensive activities of Bisoprolol.
Zolpidem Zolpidem Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Doxazosin.
Terazosin Terazosin Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Terazosin.
Isradipine Isradipine The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Isradipine.
Omeprazole Omeprazole The metabolism of Trimipramine can be decreased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Trimipramine can be decreased when combined with Cisapride.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Trimipramine is combined with Gabapentin.
Fluvastatin Fluvastatin The metabolism of Trimipramine can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Trimipramine can be decreased when combined with Venlafaxine.
Stavudine Stavudine Stavudine may increase the neurotoxic activities of Trimipramine.
Fluvoxamine Fluvoxamine The metabolism of Trimipramine can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Trimipramine.
Losartan Losartan The metabolism of Trimipramine can be decreased when combined with Losartan.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Trimipramine is combined with Tramadol.
Vinorelbine Injection Vinorelbine Injection The metabolism of Trimipramine can be decreased when combined with Vinorelbine.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Trimipramine.
Lansoprazole Lansoprazole The metabolism of Trimipramine can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Trimipramine.
Nicardipine Nicardipine Nicardipine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Bupropion Bupropion The risk or severity of seizure can be increased when Trimipramine is combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Trimipramine can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Trimipramine.
Metformin Metformin Trimipramine may decrease the hypoglycemic activities of Metformin.
Nisoldipine Nisoldipine The risk or severity of hypotension can be increased when Trimipramine is combined with Nisoldipine.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Trimipramine is combined with Riluzole.
Acarbose Acarbose Trimipramine may decrease the hypoglycemic activities of Acarbose.
Glimepiride Glimepiride The metabolism of Glimepiride can be decreased when combined with Trimipramine.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Trimipramine can be increased when it is combined with Gemcitabine.
Ritonavir Ritonavir The metabolism of Trimipramine can be decreased when combined with Ritonavir.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Trimipramine.
Zafirlukast Zafirlukast The metabolism of Trimipramine can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine Trimipramine may increase the serotonergic activities of Mirtazapine.
Trandolapril Trandolapril Trimipramine may decrease the antihypertensive activities of Trandolapril.
Topiramate Topiramate The metabolism of Trimipramine can be decreased when combined with Topiramate.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Trimipramine.
Valsartan Valsartan The metabolism of Trimipramine can be decreased when combined with Valsartan.
Insulin Lispro Injection Insulin Lispro Injection Trimipramine may decrease the hypoglycemic activities of Insulin lispro.
Pramipexole Pramipexole Trimipramine may increase the sedative activities of Pramipexole.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Trimipramine.
Nelfinavir Nelfinavir The metabolism of Trimipramine can be decreased when combined with Nelfinavir.
Fexofenadine Fexofenadine The serum concentration of Trimipramine can be increased when it is combined with Fexofenadine.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Trimipramine is combined with Azithromycin.
Carvedilol Carvedilol Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Carvedilol.
Nilutamide Nilutamide The metabolism of Trimipramine can be decreased when combined with Nilutamide.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Trimipramine.
Bicalutamide Bicalutamide The metabolism of Trimipramine can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Sertraline can be decreased when combined with Trimipramine.
Propafenone Propafenone The serum concentration of Propafenone can be increased when it is combined with Trimipramine.
Letrozole Letrozole The metabolism of Trimipramine can be decreased when combined with Letrozole.
Raloxifene Raloxifene The metabolism of Trimipramine can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Trimipramine.
Tamsulosin Tamsulosin Tamsulosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trimipramine.
Ropinirole Ropinirole Trimipramine may increase the sedative activities of Ropinirole.
Finasteride Finasteride The risk or severity of hypertension can be increased when Trimipramine is combined with Finasteride.
Quetiapine Quetiapine Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Quetiapine.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Trimipramine.
Paroxetine Paroxetine The metabolism of Paroxetine can be decreased when combined with Trimipramine.
Tolcapone Tolcapone The metabolism of Trimipramine can be decreased when combined with Tolcapone.
Citalopram Citalopram The metabolism of Citalopram can be decreased when combined with Trimipramine.
Capecitabine Capecitabine The metabolism of Trimipramine can be decreased when combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Trimipramine can be decreased when combined with Efavirenz.
Sildenafil Sildenafil The serum concentration of Trimipramine can be increased when it is combined with Sildenafil.
Pioglitazone Pioglitazone Trimipramine may decrease the hypoglycemic activities of Pioglitazone.
Celecoxib Celecoxib The metabolism of Trimipramine can be decreased when combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Trimipramine can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Trimipramine.
Thalidomide Thalidomide Trimipramine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Balsalazide Balsalazide The risk or severity of hypertension can be increased when Trimipramine is combined with Balsalazide.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Trimipramine.
Galantamine Galantamine The metabolism of Trimipramine can be decreased when combined with Galantamine.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Trimipramine is combined with Levetiracetam.
Rabeprazole Rabeprazole The metabolism of Trimipramine can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Trimipramine can be decreased when combined with Terbinafine.

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