FDA-filed SPL labeling · retrieved through openFDA

Zolmitriptan

Zolmitriptan is a triptan medication used to treat acute migraine attacks — with or without aura — in adults, and in patients 12 and older when used as a nasal spray.

Brand names Zomig-ZMTZomigZolmitriptan ODZomig Zmt
Drug class ⓘ Serotonin-1b And Serotonin-1d Receptor Agonist
Rx Forms 3 Routes Oral · Nasal
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 22 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveFeb 9, 2023
Clinical labels in scope ⓘ22
AvailabilityRx
Earliest approval/marketing year ⓘ1997
FDA-listed product records ⓘ127
Boxed warningNone found in compared labels
How we combine label and product data →
✓No current FDA shortage listed · checked Sep 23, 2026
Other forms & routes:
Nasal
⭐ Zolmitriptan at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Zolmitriptan is a well-established triptan that treats migraine attacks when they happen — it won't prevent migraines, but it can stop one that's started. Use it as soon as symptoms begin, follow your dose instructions carefully, and don't use it more than about 4 times per month without talking to your doctor. Be sure your prescriber knows your full medical history, especially any heart or blood pressure conditions, before you use it.
How we write & review this content — our editorial policy →

📖 Zolmitriptan: Patient Information Guide

A plain-language walkthrough of Zolmitriptan — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

Zolmitriptan is used to treat acute migraine attacks across several product forms. It is not used to prevent migraines — only to stop one that has already started.

  • Zomig tablets and Zolmitriptan tablets: acute migraine with or without aura in adults
  • Zolmitriptan orally disintegrating tablets and Zolmitriptan OD: acute migraine with or without aura in adults
  • Zomig Nasal Spray and Zolmitriptan Nasal Spray: acute migraine with or without aura in adults and adolescents 12 years and older
  • All forms: only use when a clear migraine diagnosis has already been made by a healthcare provider
  • No form is approved for cluster headaches or migraine prevention
  • Nasal spray forms are not recommended in patients with moderate to severe liver impairment
⚙️How it works▾

Zolmitriptan is a triptan — it works by attaching to serotonin receptors (specifically 5-HT1B and 5-HT1D receptors) found on blood vessels in the brain and on the trigeminal nerves that drive migraine pain. By activating these receptors, it causes widened cranial blood vessels to constrict (narrow back down) and blocks the release of pain-promoting chemicals from nerve endings. Both actions help relieve the throbbing pain and associated symptoms of a migraine attack. The body also converts zolmitriptan into an active breakdown product that targets the same receptors and may contribute meaningfully to the overall effect.

💊How it's taken▾

Zolmitriptan is taken at the first sign of a migraine — the sooner, the better. Tablets and orally disintegrating tablets are taken by mouth; nasal spray is used in the nose. If the migraine has not resolved or comes back after 2 hours, a second dose may be taken — but always wait at least 2 hours between doses and stay within your daily limit. Food does not significantly affect how zolmitriptan is absorbed. Use only as directed by your prescriber; the safety of treating more than about four migraines per month has not been established.

  • Tablets and orally disintegrating tablets: taken orally; may be taken with or without food
  • Nasal spray: administered into the nose; individual response may vary and dose can be adjusted by your prescriber
  • Liver impairment: lower doses are recommended for moderate to severe hepatic impairment with tablets; nasal spray is not recommended in this group
🤒Side effects — in detail▾

The most common side effects reported in clinical trials include:

  • Tingling or numbness (paresthesia)
  • Neck, throat, or jaw pain, tightness, or pressure
  • Dizziness
  • Drowsiness (somnolence)
  • Nausea
  • Warm or cold sensations
  • Dry mouth
  • Feelings of heaviness or weakness (asthenia)
  • Sweating

Chest tightness, pressure, or pain can also occur and is usually not cardiac in origin — but if you have heart disease risk factors, tell your doctor right away. Rare but serious reactions include heart rhythm problems, stroke, severe allergic reactions (including swelling of the face or throat), and serotonin syndrome — seek emergency care immediately if any of these occur.

⚠️Warnings & precautions▾
  • Cardiovascular risk: Rare but serious cardiac events — including heart attack and dangerous heart rhythms — have occurred shortly after use, even in people without known heart disease. A cardiac evaluation is recommended before use in anyone with multiple heart disease risk factors.
  • Stroke and cerebrovascular events: Cerebral hemorrhage and stroke have been reported. Zolmitriptan is contraindicated in anyone with a history of stroke or TIA.
  • Serotonin syndrome: A life-threatening reaction can occur when zolmitriptan is combined with certain antidepressants (SSRIs, SNRIs, MAO inhibitors). Symptoms include agitation, high fever, rapid heartbeat, and muscle twitching — stop taking it and get help immediately.
  • Medication overuse headache: Using any acute migraine drug too frequently (10 or more days per month) can cause headaches to worsen or become more frequent. If this happens, withdrawal and detoxification under medical supervision may be needed.
  • Blood pressure increases: Significant blood pressure elevations have been reported, especially in patients with liver impairment. Blood pressure should be monitored during treatment.
  • Vasospasm reactions: Beyond the heart, blood vessel spasm can affect the gut (causing abdominal pain and bloody diarrhea), the limbs, and other areas. Stop use and contact your doctor if these symptoms occur.
🔀What it interacts with▾

Zolmitriptan interacts with several drug types — some of these combinations are contraindicated (meaning they must be avoided):

  • Ergot-containing drugs (e.g., dihydroergotamine, methysergide) — do not use within 24 hours; both narrow blood vessels and the combined effect can be dangerous
  • Other triptans or 5-HT1 agonists — do not use within 24 hours; additive risk of blood vessel spasm
  • MAO-A inhibitors (certain antidepressants) — do not use together or within 2 weeks of stopping; zolmitriptan levels increase significantly, raising toxicity risk
  • SSRIs and SNRIs (many common antidepressants) — combination raises risk of serotonin syndrome, a potentially life-threatening condition
  • Cimetidine (a heartburn/ulcer drug) — approximately doubles zolmitriptan blood levels; dose adjustment is required if used together

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it▾
  • Tell your prescriber if you have any heart disease, coronary artery disease, history of heart attack, chest pain (angina), or Wolff-Parkinson-White syndrome
  • Tell your prescriber if you have had a stroke, TIA (mini-stroke), or have hemiplegic or basilar migraine — zolmitriptan is contraindicated in these cases
  • Tell your prescriber if you have uncontrolled high blood pressure — this is a contraindication
  • Tell your prescriber if you have peripheral vascular disease or ischemic bowel disease
  • Tell your prescriber if you have moderate or severe liver disease — nasal spray forms are not recommended, and oral doses may need to be lowered
  • Pregnancy: Animal studies showed potential for fetal harm; there are no adequate human data. Discuss the risks and benefits with your prescriber if you are or plan to become pregnant
  • Breastfeeding: It is not known if zolmitriptan passes into human breast milk; discuss with your prescriber before breastfeeding
  • Children: Not approved for patients under 12; nasal spray has established safety and efficacy in ages 12 to 17
  • Older adults: Use cautiously; a cardiovascular evaluation is recommended if heart disease risk factors are present
  • Do not use zolmitriptan if you have had a serious allergic reaction (anaphylaxis, angioedema) to it before
🚑If you take too much▾

There is limited experience with zolmitriptan overdose. In clinical studies, subjects who took a single very large oral dose commonly experienced heavy sedation. There is no specific antidote. If an overdose is suspected, seek emergency care — supportive treatment including monitoring of breathing and heart function is recommended. Because zolmitriptan's half-life is about 3 hours, patients should be monitored for at least 15 hours or until symptoms fully resolve.

📡Pharmacodynamics — effects in the body▾

Zolmitriptan activates 5-HT1B/1D serotonin receptors on intracranial blood vessels and trigeminal nerve endings. This causes cranial blood vessels to narrow (constrict) and blocks the release of pain-promoting neuropeptides, which are chemicals involved in migraine inflammation. The result is relief of migraine headache pain and associated symptoms. Zolmitriptan can also raise blood pressure, and this effect may be more pronounced in patients with liver impairment.

🔬Pharmacokinetics — how your body processes it▾

When given as a nasal spray, zolmitriptan is rapidly absorbed through the nasal passages and can be detected in the blood within 5 minutes; peak blood levels are typically reached around 3 hours. The nasal spray has bioavailability comparable to the oral tablet. Food does not meaningfully affect absorption of the oral form. Zolmitriptan is converted in the body to an active metabolite that is 2 to 6 times more potent at the target receptors. Both zolmitriptan and its active metabolite have an elimination half-life of about 3 hours, and the drug is cleared mainly through the urine and feces. Blood levels can be significantly higher in patients with severe liver disease, and women tend to have somewhat higher plasma concentrations than men.

📦How to store it▾

Store at 20°C to 25°C (68°F to 77°F) . Protect from light and moisture. Dispense in a tight, light-resistant closed container.

📄 Written from Zolmitriptan’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

50

Supplements & herbs that interact with Zolmitriptan

50 supplements and herbal products have documented interactions with Zolmitriptan in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 8
  • Moderate · 31
  • Minor · 11
ACTIVATED CHARCOAL Major AMERICAN HELLEBORE Major ARSENIC Major CESIUM Major EPHEDRA Major GRAPEFRUIT Major LITHIUM Major SIDA CORDIFOLIA Major +42 more
Every supplement checked against Zolmitriptan — ranked by severity The full interaction hub: 8 major · 31 moderate · 11 minor · every one linked to its full report. Check Zolmitriptan against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Zolmitriptan — the kind of thing our pharmacy team would talk through with you at the counter.

What exactly does zolmitriptan do — will it stop my migraine or just take the edge off? ▾
Zolmitriptan is designed to treat a migraine that's already started, not just dull the pain a little. It works on specific receptors in the brain to help narrow the widened blood vessels and stop the release of pain-triggering chemicals that drive a migraine. Many people get significant relief, though response can vary from person to person. The key is to take it as early in the migraine as you can — the sooner you take it after symptoms begin, the better it tends to work.
Can I take it again if my headache comes back a few hours later? ▾
Yes — if your migraine hasn't fully gone away after 2 hours, or if it comes back after initially getting better, you can take a second dose. You just need to wait at least 2 hours between doses. Keep in mind there's a daily maximum — don't go over what your prescriber has told you is your limit in a 24-hour period. If you find you need it very frequently, talk to your doctor, because using it more than about 10 days a month can actually make headaches worse over time.
What side effects should I actually expect, and which ones should make me call someone? ▾
The most common things people notice are tingling or numbness, dizziness, a feeling of pressure or tightness in the neck, throat, or jaw, drowsiness, and sometimes nausea. These are uncomfortable but usually not dangerous. What you should call about right away is chest pain or tightness, sudden vision changes, weakness on one side, trouble speaking, a very fast or irregular heartbeat, or severe stomach pain with bloody diarrhea — those are signs of potentially serious problems that need medical attention quickly. Also call if you feel unusually agitated, confused, or feverish alongside muscle twitching, as that could signal a rare but serious drug interaction.
Are there medications I absolutely cannot take with this? ▾
Yes — a few combinations are a hard no. Don't take zolmitriptan within 24 hours of using another triptan or any ergot-type migraine drug like dihydroergotamine. If you take an MAO inhibitor antidepressant (like phenelzine or tranylcypromine), you need to wait at least 2 weeks after stopping it before using zolmitriptan. Even combining it with common antidepressants like SSRIs or SNRIs requires caution because of a risk called serotonin syndrome. Also, a common heartburn drug called cimetidine can roughly double zolmitriptan's levels in your blood, so your doctor would need to adjust your dose if you use both. Always share your full medication list with your prescriber.
I'm pregnant — is it safe to use this for migraines? ▾
This one warrants a real conversation with your doctor before using it. Animal studies did show some signs of potential harm to fetuses, though we don't have solid human data to draw firm conclusions. Migraines during pregnancy are a real problem and going untreated has its own risks — so your prescriber can help you weigh the benefits versus the unknowns. Don't stop or start any migraine treatment during pregnancy without that conversation first.
Can my teenager use zolmitriptan nasal spray? ▾
Yes — the nasal spray form has been studied and has established safety and effectiveness for adolescents 12 to 17 years old, and it is approved for that age group. The tablets (regular or orally disintegrating) are approved for adults, and the nasal spray is specifically what has been evaluated in kids 12 and older. If your teen has been diagnosed with migraines, talk to their doctor about whether zolmitriptan nasal spray is appropriate for them.
Is Zolmitriptan available over the counter? ▾
Zolmitriptan is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.
When was Zolmitriptan first available? ▾
Zolmitriptan has been available in the United States since at least 1997, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Zolmitriptan? ▾
Zolmitriptan is supplied by 38 manufacturers listed in the FDA NDC Directory, including Alembic Pharmaceuticals Limited, Amneal Pharmaceuticals, Aurobindo Pharma Limited.

💬 Answers drafted from Zolmitriptan’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

📊Zolmitriptan supplement interactions50 checked — ranked by severity 🌿Drug & Supplement CheckerZolmitriptan vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Zolmitriptan NDCs & costs 🅰️Browse Drugs A–ZLook up any medication

💊 How Zolmitriptan comes

Zolmitriptan is available in 3 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Tablet

By mouth
Brands Zomig
How this form is used
What it may be used for
  • Zomig tablets are approved for acute treatment of migraine with or without aura in adults
  • Zolmitriptan tablets are approved for acute treatment of migraine with or without aura in adults
  • Not approved for migraine prevention or cluster headaches
Important instructions
  • Zomig tablets and Zolmitriptan tablets are taken by mouth at the onset of a migraine; food does not significantly affect absorption
  • The 2.5 mg tablet is scored and can be broken in half to achieve a lower starting dose if directed by a prescriber
  • A second dose may be taken at least 2 hours after the first if the migraine has not resolved or returns
  • Patients with moderate or severe liver impairment should use a lower starting dose as directed by their prescriber
Available strengths 2 strengths
2.5 mg 5 mg
69 FDA-listed product records ⓘ

Orally disintegrating tablet

By mouth
Brands Zolmitriptan OD Zomig Zmt
How this form is used
What it may be used for
  • Zolmitriptan orally disintegrating tablets are approved for acute treatment of migraine with or without aura in adults
  • Zolmitriptan OD orally disintegrating tablets are approved for acute treatment of migraine with or without aura in adults
  • Not approved for migraine prevention or cluster headaches
Important instructions
  • Orally disintegrating tablets are taken by mouth and dissolve on the tongue — do not break the tablet
  • A second dose may be taken at least 2 hours after the first if the migraine has not resolved or returns
  • Do not exceed the maximum daily limit in any 24-hour period — follow your prescriber's guidance
  • Patients with moderate or severe liver impairment should use a lower starting dose as directed by their prescriber
Available strengths 2 strengths
2.5 mg 5 mg
34 FDA-listed product records ⓘ

Nasal spray

In the nose
Brands Zomig
How this form is used
What it may be used for
  • Zomig Nasal Spray is approved for acute treatment of migraine with or without aura in adults and adolescents 12 years of age and older
  • Zolmitriptan Nasal Spray is approved for acute treatment of migraine with or without aura in adults and adolescents 12 years of age and older
  • Not approved for migraine prevention or for cluster headaches
  • Not recommended in patients with moderate to severe liver impairment
Important instructions
  • Zomig Nasal Spray and Zolmitriptan Nasal Spray are administered into the nose at the onset of a migraine
  • A second dose may be given at least 2 hours after the first if the migraine has not resolved or returns
  • Do not exceed the maximum daily amount in any 24-hour period — follow your prescriber's instructions
  • Safety for treating more than four migraines per 30-day period has not been established
Available strengths 2 strengths
2.5 mg 5 mg
14 FDA-listed product records ⓘ

📊 Zolmitriptan across the U.S. market

How Zolmitriptan appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

3
Dose forms ⓘ
38
Manufacturers
5
Brand names
127
FDA-listed product records ⓘ
1997
First marketed ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (10) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Alembic Pharmaceuticals Limited8%
Amneal Pharmaceuticals6%
Aurobindo Pharma Limited6%
Glenmark Pharmaceuticals Inc.,USA5%
Zydus Pharmaceuticals USA Inc.5%
Zydus Lifesciences Limited5%
Other makers66%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Zolmitriptan is used

A general measure of how commonly Zolmitriptan is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Zolmitriptan is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

27,026
Medicaid prescriptions filled (Q1–Q4 2025)
$2.9M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Zolmitriptan prescribed? Of the 1,596 medications we measure, Zolmitriptan ranks #756 by Medicaid prescriptions — more than 53% of them.

Where Zolmitriptan ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #756 of 1,596
#751 Alirocumab Injection 27,746 Rx #752 Dexmedetomidine 27,524 Rx #753 Golimumab Injection 27,172 Rx #754 Metronidazole Injectio... 27,056 Rx #755 Emicizumab 27,047 Rx #756 Zolmitriptan 27,026 Rx #757 Abemaciclib 27,007 Rx #758 Ampicillin and Sulbact... 26,484 Rx #759 Ampicillin / Sulbactam 26,484 Rx #760 Zoledronic Acid Inject... 26,317 Rx #761 Zoledronic Acid 26,317 Rx

Utilization by Zolmitriptan product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 5 mg oral tablet is the most-dispensed Zolmitriptan product — about 51% of these Medicaid prescriptions.

zolmitriptan 5 MG Oral Tablet Most dispensed

13,892 Medicaid prescriptions (Q1–Q4 2025) 51% of Zolmitriptan prescriptions shown $357,088 gross reimbursement (before rebates) ≈ $26 per prescription (gross)

Summed across the 6 of 29 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 200194

zolmitriptan 5 MG/ACTUAT Nasal Spray

5,861 Medicaid prescriptions (Q1–Q4 2025) 22% of Zolmitriptan prescriptions shown $2.2M gross reimbursement (before rebates) ≈ $376 per prescription (gross)

Summed across the 3 of 12 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 402000

zolmitriptan 5 MG Disintegrating Oral Tablet

3,367 Medicaid prescriptions (Q1–Q4 2025) 12% of Zolmitriptan prescriptions shown $135,439 gross reimbursement (before rebates) ≈ $40 per prescription (gross)

Summed across the 3 of 25 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 351134

zolmitriptan 2.5 MG Oral Tablet

3,248 Medicaid prescriptions (Q1–Q4 2025) 12% of Zolmitriptan prescriptions shown $77,858 gross reimbursement (before rebates) ≈ $24 per prescription (gross)

Summed across the 4 of 29 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 200193

zolmitriptan 2.5 MG Disintegrating Oral Tablet

526 Medicaid prescriptions (Q1–Q4 2025) 2% of Zolmitriptan prescriptions shown $18,265 gross reimbursement (before rebates) ≈ $35 per prescription (gross)

Summed across the 3 of 25 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 284201

zolmitriptan 2.5 MG/ACTUAT Nasal Spray

132 Medicaid prescriptions (Q1–Q4 2025) <1% of Zolmitriptan prescriptions shown $85,047 gross reimbursement (before rebates) ≈ $644 per prescription (gross)

Summed across the 2 of 3 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1483677

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Zolmitriptan, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 21 of 123 listed Zolmitriptan NDCs with Medicaid activity.

🔍 Compare Zolmitriptan products

A representative set of FDA-listed product records for Zolmitriptan — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 127 of 127 products — FDA National Drug Code Directory. See every product, package size and price: browse all 127 Zolmitriptan NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Zolmitriptan RxCUI 135775 3 dose forms · 6 strengths
  1. Dose form (SCDF) Disintegrating Oral Tablet RxCUI 374653 In current FDA listings
    Clinical drug / strength (SCD) 2.5 MG RxCUI 284201 5 MG RxCUI 351134
  2. Dose form (SCDF) Nasal Spray RxCUI 402420 In current FDA listings
    Clinical drug / strength (SCD) 2.5 MG/ACTUAT RxCUI 1483677 5 MG/ACTUAT RxCUI 402000
  3. Dose form (SCDF) Oral Tablet RxCUI 374363 In current FDA listings
    Clinical drug / strength (SCD) 2.5 MG RxCUI 200193 5 MG RxCUI 200194

Look up RxCUI 135775 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Zomig-ZMT Zomig Zolmitriptan OD Zomig Zmt

🏭 Manufacturers & labelers

Alembic Pharmaceuticals Limited 10 Amneal Pharmaceuticals 8 Aurobindo Pharma Limited 7 Glenmark Pharmaceuticals Inc.,USA 6 Zydus Pharmaceuticals USA Inc. 6 Zydus Lifesciences Limited 6 Glenmark Pharmaceuticals Inc., USA 6 Alembic Pharmaceuticals Inc. 6 Amneal Pharmaceuticals LLC 6 Rising Pharmaceuticals, Inc. 4 BluePoint Laboratories 4 Bryant Ranch Prepack 4 Rising Pharma Holdings, Inc. 4 PLD Acquisitions LLC DBA Avma Pharma Solutions 4 Direct_Rx 4 Ajanta Pharma USA Inc. 4 Medstone Pharma LLC 4 Jubilant Cadista Pharmaceuticals Inc. 4 Amneal Pharmaceuticals NY LLC 2 Quality Care Products, LLC 2 PLD Acquisitions LLC DBA Av�ma Pharma Solutions 2 Padagis Israel Pharmaceuticals Ltd 2 Jubilant Cadista Pharmacuticals Inc. 2 Ingenus Pharmaceuticals, LLC 2

…and 14 more on the FDA NDC directory.

RxNorm drug class

Zolmitriptan belongs to the Serotonin-1b and Serotonin-1d Receptor Agonist class.

Pharmacologic class Serotonin-1b and Serotonin-1d Receptor Agonist
Drug family (ATC) Selective serotonin (5HT1) agonists
How it works Serotonin 1b Receptor Agonists, Serotonin 1d Receptor Agonists

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Feb 9, 2023
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Zolmitriptan.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Zolmitriptan after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
22
NDC products indexed
127
Distinct labelers/manufacturers represented
38
Linked representative label ⓘ
PLD Acquisitions LLC DBA Av�ma Pharma Solutions
Linked label effective
Feb 9, 2023
Composite sections available
22
Linked SPL Set ID
f59bfbdd-7f4b-4a29-8396-e144dde65878
Linked SPL Document ID
bf9467df-5c81-4b04-8ca3-e3f9104132e9
Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 22 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. PLD Acquisitions LLC DBA Av�ma Pharma Solutions is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.