Hemorrhoidal Mineral Oil, Petrolatum, Phenylephrine HCI .25 g/100g; 14 g/100g; 74.9 g/100g Ointment — NDC 00536-1288-06 package photo

Hemorrhoidal Mineral Oil, Petrolatum, Phenylephrine HCI .25 g/100g; 14 g/100g; 74.9 g/100g Ointment

by Rugby · 1 TUBE in 1 BOX (0536-1288-06) / 57 g in 1 TUBE
NDC 00536-1288-06
🏷️ FDA NDC (as labeled) 0536-1288-06 billing pads the labeler segment with a zero
OTC On market Non-controlled
🗂️ Data synced Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

🆔 Identity & classification

FDA NDC (as labeled) 0536-1288-06
Product NDC 0536-1288
11-digit billing NDC 00536128806
NCPDP billing unit GM — per gram (weight)
RxCUI 1372298
UNII 04JA59TNSJ, T5L8T28FGP, 4T6H12BN9U
Application # M015
SPL Set ID a5b5e0a9-eee9-2a1e-e053-2a95a90a464e
Established class (EPC) alpha-1 Adrenergic Agonist
Mechanism of action Adrenergic alpha1-Agonists
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2020-05-14
Route TOPICAL
Dosage form OINTMENT
Substance PHENYLEPHRINE HYDROCHLORIDE; MINERAL OIL; PETROLATUM
GPI-14 89994003224222
GPI class Hemorrhoidal
GCN Seq No 071294
GCN 35039
HICL code 039599
Ingredient (HICL) Phenyleph/Mineral Oil/Petrolat
HIC1 code Q
Therapeutic class — broad (HIC1) Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code Q3
Therapeutic class — intermediate (HIC2) Anal-Rectal Preparations
HIC3 code Q3D
Therapeutic class — specific (HIC3) Hemorrhoidal Preparations
AHFS code 12:12.04.00
AHFS class Alpha-Adrenergic Agonists (12:12)
FDB label name HEMORRHOIDAL OINTMENT
FDB brand name Hemorrhoidal Ointment
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 0536-1288-06 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00536-1288-06. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Softeners, emollients class.

Drug family (ATC) Softeners, emollients
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerRugby
FDA applicationM015 (OTC MONOGRAPH DRUG)
Labeler code00536
First marketedMay 2020
Product typeHuman Otc Drug
Portfolio2 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name HEMORRHOIDAL OINTMENT Ingredient Phenyleph/Mineral Oil/Petrolat
🧪 What is this product?

This is an over-the-counter topical ointment marketed under FDA's monograph rules for hemorrhoidal products. It contains phenylephrine hydrochloride, a decongestant ingredient typically used to reduce swelling and provide temporary relief in hemorrhoidal tissue. Mineral oil and petrolatum are lubricating and protective agents commonly included in such products to soften stool passage and soothe irritated skin. The ointment is applied directly to the affected area for localized symptom management.

Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 8SKN0B0MIM
    Benzoic acid is a naturally occurring organic acid used as a preservative in medicines and foods. It helps prevent bacterial and fungal growth to extend shelf life and maintain product stability.
  • UNII 936JST6JCN
    Cetyl alcohol is a waxy, fatty substance derived from plant or animal sources. It acts as an emulsifier and thickener in medicines, helping blend oil and water components and giving products a smooth, creamy texture.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII N72LMW566G
    A synthetic cleansing agent derived from lauryl alcohol and ethylene oxide. It helps dissolve and mix oil and water-based ingredients in liquid medicines, acting as an emulsifier and solubilizer.
  • UNII A2I8C7HI9T
    Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
  • UNII Z8IX2SC1OH
    Propylparaben is a chemical preservative used to prevent bacterial and fungal growth in medicines and personal care products. It helps extend shelf life and maintain product safety during storage.
  • UNII 2KR89I4H1Y
    Stearyl alcohol is a waxy, fatty substance derived from natural oils or made synthetically. It acts as an emulsifier and thickener in medicines, helping mix ingredients together and give the product the right texture.
  • UNII 2ZA36H0S2V
    Beeswax is a natural wax produced by honeybees. In medicines, it works as a coating agent and thickener to control how fast the drug dissolves and improve the product's texture and appearance.

8 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesBeeswax, Benzoic Acid, Cetyl alcohol, Glycerol Methylparaben, Polyoxyethylene lauryl ether, Propylparaben, Stearyl alcohol

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMedingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly $0.054 $3.10 / 57 g
Medicaid paysCMS SDUD · 12 mo $0.1459 $8.32 / 57 g
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per g) — tap or hover for the price & month
Dec 2021 Aug 2022 Dec 2025 Aug 2026 $0.055 $0.041
▲ Up 29% over the last 23 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Good Sense Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 00113-0188-16 L. 1 tube $0.054 Availability likely
Hemorrhoidal .25 g/100g; 14 g/100g; 74.9 g/100gthis 00536-1288-06 Rugby 1 tube $0.054 Availability likely
Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 45802-0188-16 Padagis 1 tube $0.054 Availability likely
GNP Hemorrhoidal 2.5 mg/g; 749 mg/g; 140 mg/g 46122-0677-46 Amerisource 1 tube $0.054 Availability likely
Hemorrhoidal .25 g/100g; 14 g/100g; 74.9 g/100g 70000-0046-01 Cardinal 1 tube $0.054 Availability likely
foster and thrive hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 70677-1108-01 Strategic 1 tube $0.054 Availability likely
Walgreens 2.5 mg/g; 140 mg/g; 749 mg/g 00363-6503-01 Walgreens 1 tube FDA listed
Hemorrhoidal Pain Relief 2.5 mg/g; 140 mg/g; 749 mg/g 00363-9876-02 WALGREENS 1 tube FDA listed
Preparation H 2.5 mg/g; 140 mg/g; 749 mg/g 00573-2871-04 Haleon 1 tube FDA listed
Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 11822-0006-00 Rite 1 tube Discontinued
Hemorrhoidal 2.5 mg/g; 749 mg/g; 140 mg/g 13709-0319-01 NeilMed 1 tube FDA listed
Hemorrhoidal Pain Relief 749 mg/g; 140 mg/g; 2.5 mg/g 13709-0334-01 Neilmed 1 tube FDA listed
signature care hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 21130-0577-16 Safeway 1 tube FDA listed
Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 21130-0687-16 Safeway 1 tube FDA listed
Signature Care Hemorrhoidal 749 mg/g; 2.5 mg/g; 140 mg/g 21130-0789-14 Better 1 tube FDA listed
Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 30142-0188-16 Kroger 1 tube FDA listed
topcare hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 36800-0499-16 Topco 1 tube FDA listed
Equaline Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 41163-0188-16 United 1 tube FDA listed
hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 41250-0188-16 Meijer 1 tube FDA listed
careone hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 41520-0188-16 American 1 tube FDA listed
0.25 % PHENYLEPHRINE HCl HEMORRHOIDAL 14 g/100g; 74.9 g/100g; .25 g/100g 43473-0094-02 Nantong 1 tube FDA listed
Equate Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 49035-0188-16 Wal-Mart 1 tube FDA listed
Hemorrhoidal 140 mg/g; 749 mg/g; 2.5 mg/g 51316-0228-01 CVS 1 tube FDA listed
CAREALL Hemorrhoidal 140 mg/g; 749 mg/g; 2.5 mg/g 51824-0079-02 New 56 g FDA listed
Hemorrhoid Anesthetic .14 g/g; .749 g/g; .0025 g/g 52000-0057-01 Universal 1 tube Discontinued
0.25 % PHENYLEPHRINE HCl HEMORRHOIDAL 14 g/100g; 74.9 g/100g; .25 g/100g 52000-0438-02 Universal 1 tube FDA listed
Exchange Select Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 55301-0188-16 Army 1 tube FDA listed
Family Wellness Hemorrhoidal 749 mg/g; 140 mg/g; 2.5 mg/g 55319-0381-56 Family 1 tube FDA listed
TheraPlus Plus .25 g/100g; 14 g/100g; 74.9 g/100g 55621-0005-01 Zhejiang 42 g FDA listed
Family Wellness .25 g/100g; 14 g/100g; 74.9 g/100g 55621-0006-01 Zhejiang 1 tube FDA listed
ProCure Hemorrhoidal 74.9 g/100g; .25 g/100g; 14 g/100g 55681-0021-02 Twin 56.6 g FDA listed
DG Health Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 55910-0188-16 Dolgencorp, 1 tube FDA listed
Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 56062-0188-16 Publix 1 tube FDA listed
Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 63187-0505-02 Proficient 1 tube FDA listed
HemorrhoidalOintment 14 g/100g; 74.9 g/100g; .25 g/100g 68016-0528-00 Pharmacy 1 tube FDA listed
HemorrhoidalOintment 14 g/100g; 74.9 g/100g; .25 g/100g 69396-0020-01 Trifecta 1 tube FDA listed
HemorrhoidalOintment 14 g/100g; 74.9 g/100g; .25 g/100g 69396-0082-02 Trifecta 1 tube FDA listed
HemorrhoidalOintment 74.9 g/100g; .25 g/100g; 14 g/100g 69396-0083-01 Trifecta 1 tube FDA listed
HemorrhoidalOintment 14 g/100g; 74.9 g/100g; .25 g/100g 69396-0133-20 Trifecta 1 tube FDA listed
hemorrhoidal 749 mg/g; 2.5 mg/g; 140 mg/g 69452-0448-38 Bionpharma 1 tube FDA listed
Family wellness 14 g/100g; 74.9 g/100g; .25 g/100g 69571-0006-02 FRONT 1 tube FDA listed
TheraCare Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 71101-0935-01 Veridian 1 tube FDA listed
Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 72162-2282-02 Bryant 1 tube FDA listed
Basic Care Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 72288-0188-16 Amazon.com 1 tube FDA listed
Hemorrhoidal .25 g/100g; 14 g/100g; 74.9 g/100g 83324-0045-02 Chain 1 tube FDA listed
Hemorrhoidal 14 g/100g; 74.9 g/100g; .25 g/100g 85766-0140-57 Sportpharm 1 tube FDA listed
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2020
On the market since
May 2020
📍
2026
Currently FDA-listed
6 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🗺️ Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 00536-1288-06, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q4 2025 · 4 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
1.4K
Units reimbursed last 4 qtrs
82.1K
Gross reimbursed last 4 qtrs
$12K
Avg / prescription
$8.47
Avg / unit
$0.1459
Latest quarter Q4 2025
311Rx
Medicaid pays / g
$0.1459
gross reimbursed
vs
NADAC / g
$0.0544
acquisition cost
=
Spread
+$0.0915
+168% vs cost
What Medicaid paid per g (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care
17% FFS 83% MCO
Fee-for-service · 244 Rx Managed care · 1,170 Rx
State Medicaid map
Alaska: no data reported AK Maine: no data reported ME Washington: no data reported WA Idaho: no data reported ID Montana: no data reported MT North Dakota: no data reported ND Minnesota: 9,803 units · 171 per 100k residents MN Wisconsin: no data reported WI Michigan: no data reported MI New York: no data reported NY Vermont: no data reported VT New Hampshire: no data reported NH Oregon: no data reported OR Nevada: 4,047 units · 127 per 100k residents NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: 684 units · 5.5 per 100k residents IL Indiana: 26,361 units · 384 per 100k residents IN Ohio: 14,878 units · 126 per 100k residents OH Pennsylvania: 5,016 units · 38.7 per 100k residents PA New Jersey: 5,183 units · 55.8 per 100k residents NJ Massachusetts: no data reported MA California: 1,254 units · 3.2 per 100k residents CA Utah: no data reported UT Colorado: no data reported CO Nebraska: 9,141 units · 462 per 100k residents NE Missouri: no data reported MO Kentucky: no data reported KY West Virginia: no data reported WV Virginia: 2,129 units · 24.4 per 100k residents VA Maryland: no data reported MD Connecticut: no data reported CT Rhode Island: no data reported RI Arizona: 2,165 units · 29.1 per 100k residents AZ New Mexico: no data reported NM Kansas: no data reported KS Arkansas: no data reported AR Tennessee: no data reported TN North Carolina: no data reported NC South Carolina: no data reported SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: no data reported MS Alabama: no data reported AL Georgia: no data reported GA D.C.: no data reported DC Hawaii: no data reported HI Texas: 1,452 units · 4.8 per 100k residents TX Florida: no data reported FL
Units reimbursed · per 100k residents
3.2462
gray = no data reported
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Nebraska 462 /100k
2 Indiana 384 /100k
3 Minnesota 171 /100k
4 Nevada 127 /100k
5 Ohio 126 /100k
6 New Jersey 55.8 /100k
7 Pennsylvania 38.7 /100k
8 Arizona 29.1 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Hemorrhoidal (this brand).

Top reported reactions

Pain11
Dyspnoea7
Nausea7
Fatigue6
Constipation5
Death5
Pneumonia5

Age at onset

Adult6
Elderly6

Reporter sex

73 reports
Male · 44%
Female · 56%

Serious outcomes

Hospitalization17
Life-threatening4
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 4 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
00536-1288-06 You're viewing this 1 TUBE in 1 BOX (0536-1288-06) / 57 g in 1 TUBE 2020-05-14 Active

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage 41 words

Uses Helps relieve the local itching and discomfort associated with hemorrhoids Temporarily shrinks hemorrhoidal tissue and relieves burning Temporarily provides a coating for relief of anorectal discomforts Temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful

⏱️ Dosage and Administration 117 words

Directions Children under 12 years of age; ask doctor before use Adults: when practical, clean the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or soft cloth before applying. When first opening tube, remove foil seal Apply externally to the affected area up to 4 times daily, especially at night, in the morning or after each bowel movement.

For intrarectal use: remove protective cover from applicator and attach to tube. Lubricate applicator well then gently insert applicator into the rectum. Thoroughly clean applicator and replace protective cover after each use.

Regular use provides continual therapy for relief of symptoms also apply ointment to external area.

⚠️ Warnings 48 words

Warnings For external and/or intrarectal use only Ask doctor before use if you have heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland Ask doctor before use if you are presently taking a prescription drug for high blood pressure or depression.

📦 Storage and Handling 8 words

Other Information Store at room temperature 20º-25ºC (68º-77ºF)

🧪 Active Ingredient 14 words

Active Ingredient Phenylephrine HCI 0.25%

Active Ingredient Mineral Oil 14%

Active Ingredient Petrolatum 74.9%

🧪 Inactive Ingredients 15 words

Inactive Ingredients Beeswax, Benzoic Acid, Cetyl alcohol, Glycerol Methylparaben, Polyoxyethylene lauryl ether, Propylparaben, Stearyl alcohol

🎯 Purpose 6 words

Purpose Vasoconstrictor

Purpose Protectant

Purpose Protectant

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.