Rugby Lidocaine Lidocaine 4% 4 g/100g Cream
by Rugby Laboratories · 1 TUBE in 1 BOX (0536-1357-95) / 28 g in 1 TUBE
NDC 00536-1357-95
🏷️ FDA NDC (as labeled)
0536-1357-95
billing pads the labeler segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
0536-1357-95
Product NDC
0536-1357
11-digit billing NDC
00536135795
NCPDP billing unit
GM — per gram (weight)
RxCUI
1421893
UNII
98PI200987
UPC
0305361357955
Application #
M017
SPL Set ID
d94292f7-10fc-48bf-e053-2995a90a8472
Established class (EPC)
Amide Local Anesthetic; Antiarrhythmic
Physiologic effect
Local Anesthesia
Chemical class
Amides
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2022-03-02
Route
TOPICAL
Dosage form
CREAM
Substance
LIDOCAINE
GPI-14
90850060003720
GPI class
Lidocaine
GCN Seq No
040262
GCN
95405
HICL code
010705
Ingredient (HICL)
Lidocaine
HIC1 code
Q
Therapeutic class — broad (HIC1)
Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code
Q5
Therapeutic class — intermediate (HIC2)
Agents Acting Principally On The Skin
HIC3 code
Q5H
Therapeutic class — specific (HIC3)
Topical Local Anesthetics
AHFS code
72:00.00.00
AHFS class
Local Anesthetics
FDB label name
LIDOCAINE 4% CREAM
FDB brand name
Lidocaine
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 0536-1357-95 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00536-1357-95. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Antiarrhythmic class.
Pharmacologic class
Antiarrhythmic, Amide Local Anesthetic
Drug family (ATC)
Antiarrhythmics, class Ib, Local anesthetics, Anesthetics for topical use
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerRugby Laboratories
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code00536
First marketedMar 2022
Product typeHuman Otc Drug
Portfolio149 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name LIDOCAINE 4% CREAM Ingredient Lidocaine
📗 Our plain-language guide HelloPharmacist
- It's best to avoid using two lidocaine products at the same time unless your doctor says it's okay. When you use multiple products containing a local anesthetic, the total amount a...
- Can I use a lidocaine patch and a lidocaine cream at the same time?
- No — please don't do this. Heat significantly increases how much lidocaine is absorbed through your skin, which can push drug levels in your blood higher than they should be. Stick...
- Can I put a heating pad on the area where I applied a lidocaine patch?
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Lidocaine 4%?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.410 | $11.47 / 28 g |
| Medicaid paysCMS SDUD · 12 mo | $0.6151 | $17.22 / 28 g |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per g) — tap or hover for the price & month
▼ Down 7% over the last 9 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Rugby Lidocaine 4 g/100gthis 00536-1357-95 | Rugby | 1 tube | $0.410 | — | Availability likely | — |
| Lidocaine 4% Topical Anesthetic Cream 4 g/100g 83720-0523-01 | Oncor | 1 tube | $0.482 | — | Availability likely | +18% |
| 4 Lidocaine Topical Anesthetic 40 mg/g 00536-1267-20 | RUGBY | 15 g | $0.597 | — | Availability likely | +46% |
| Lidocaine 40 mg/g 39328-0024-15 | Patrin | 1 tube | $0.597 | — | Availability likely | +46% |
| Numbing Pain Relief 4 g/100g 00363-6261-07 | Walgreen | 1 applicator | — | — | FDA listed | — |
| Lmx4 40 mg/g 00496-0882-05 | Ferndale | 5 g | — | — | FDA listed | — |
| Lidocaine 40 mg/g 10135-0672-96 | Marlex | 1 tube | — | — | FDA listed | — |
| Anecream 4 g/100g 24357-0701-06 | Focus | 5 tubes | — | — | FDA listed | — |
| Meijer Analgesic Lidocaine Topical Analgesic 40 mg/g 41250-0518-01 | Meijer | 1 bottle | — | — | FDA listed | — |
| Lidocaine 4 g/100g 42291-0399-30 | AvKARE | 1 tube | — | — | FDA listed | — |
| Pain free IV 4 g/100mL 54723-0008-01 | Sambria | 4 ml | — | — | FDA listed | — |
| Painless Tattoo 2 4 g/100mL 54723-0016-01 | Sambria | 4 ml | — | — | FDA listed | — |
| NeuroMed Topical Anesthetic 7 40 mg/g 54723-0300-04 | Sambria | 4 g | — | — | FDA listed | — |
| Family Wellness Pain Relief with Lidocaine 40 mg/g 55319-0822-50 | FAMILY | 1 tube | — | — | FDA listed | — |
| Lidocaine 40 mg/g 58980-0824-05 | Stratus | 1 tube | — | — | FDA listed | — |
| Burn Relief Professional Bio-Kool 4 g/100g 61566-0201-04 | Kool-Down | 113 g | — | — | FDA listed | — |
| Desert Harvest RELEVEUM 40 mg/mL 69145-0201-04 | Desert | 118 ml | — | — | FDA listed | — |
| Lidocaine Anesthetic Cream 4 g/100g 69375-0005-30 | Nationwide | 1 tube | — | — | FDA listed | — |
| Tylenol Precise Warming Pain Relieving 40 mg/g 69968-0794-04 | Kenvue | 1 tube | — | — | FDA listed | — |
| Tylenol Precise Pain Relieving 40 mg/g 69968-0795-04 | Kenvue | 1 tube | — | — | FDA listed | — |
| Blue-Emu Lidocaine Pain Relief Cream 40 mg 69993-0350-03 | Kingsway | 1 tube | — | — | FDA listed | — |
| Lidocaine Cream, 4% 4 g/100g 71085-0075-19 | IPG | 119 g | — | — | FDA listed | — |
| Deeveeant Numb 40 mg/g 71383-0014-02 | Valekista | 1 tube | — | — | FDA listed | — |
| MediNumb 40 mg/g 71383-0024-02 | Valekista | 1 tube | — | — | FDA listed | — |
| Asper Flex 4 g/100g 71399-0049-01 | Akron | 15 g | — | — | FDA listed | — |
| Lidocaine 4% 4 g/100g 71800-0026-06 | Innovida | 58.5 g | — | — | FDA listed | — |
| Lidozall 4 g/100g 72835-0004-20 | V2 | 20 packets | — | — | FDA listed | — |
| Lidocaine 4% Topical Anesthetic Cream 4.27 g/100g 73715-0001-01 | Mohnark | 30 g | — | — | Discontinued | — |
| Meijer Pain Relief Cream 4 g/100g 79481-0048-02 | Meijer | 76.5 g | — | — | FDA listed | — |
| Lidocaine 40 mg/g 80425-0351-01 | Advanced | 1 tube | — | — | FDA listed | — |
| Lidocaine 4% Cream 40 mg/g 82461-0419-30 | Medcore | 1 tube | — | — | FDA listed | — |
| AUVON Pain Relief Cream 4 g/100g 83391-0009-01 | SHENZHEN | 57 g | — | — | FDA listed | — |
| RelaxInk LIDOCAINE 4 g/100g 83714-0004-01 | Hambli | 1 tube | — | — | FDA listed | — |
| ELAIMEI Numbing Cream 4 g/100mL 83804-0005-01 | Shenzhen | 1 bottle | — | — | FDA listed | — |
| Tktalker Numbing 4 g/100g 83804-0113-01 | Shenzhen | 50 g | — | — | FDA listed | — |
| Dcsily Numbing Cream 4 g/100g 83818-0034-01 | Shenzhen | 50 g | — | — | FDA listed | — |
| 4% TATTOO Numb Cream 100 mg/g 84019-0030-01 | Shengnan | 30 g | — | — | FDA listed | — |
| Signature Pain Relief Cream 40 mg/g 84019-0044-01 | Shengnan | 30 g | — | — | FDA listed | — |
| Nekvnro LIDOCAINE 4% Tattoo numbing cream set 4 g/100g 84844-0018-01 | Guoyu | 2 tubes | — | — | Discontinued | — |
| VBBV Tattoo Numbing 40 mg/mL 84867-0014-01 | Jiashen | 60 ml | — | — | FDA listed | — |
| Black Cobra Tattoo Numbing Cream 4% Lidocaine .04 g/g 84938-0002-01 | Foshan | 20 g | — | — | FDA listed | — |
| Jakwork Numbing Cream 4 g/100g 85150-0007-01 | Guangzhou | 50 g | — | — | FDA listed | — |
| Healmusz Numbing 4 g/100g 85248-0032-01 | Jiangxi | 50 g | — | — | FDA listed | — |
| Nieapf NUMBING 4 g/100g 85248-0046-01 | Jiangxi | 65 g | — | — | FDA listed | — |
| Subleef NUMBING 4 g/100g 85248-0052-01 | Jiangxi | 30 g | — | — | FDA listed | — |
| Sylvirene Numbing 4 g/100g 85248-0070-01 | Jiangxi | 50 g | — | — | FDA listed | — |
| ANIXIKE Numbing 4 g/100g 85248-0088-01 | Jiangxi | 30 g | — | — | FDA listed | — |
| Dermfree Numbing 4 g/100g 85248-0121-01 | Jiangxi | 50 g | — | — | FDA listed | — |
| ANIXIKE Numbing 4 g/100g 85248-0166-01 | Jiangxi | 30 g | — | — | FDA listed | — |
| YYSDMVY NUMBING Cream 4 g/100g 85248-0209-01 | Jiangxi | 60 g | — | — | FDA listed | — |
| Tattoo numbing cream 4 g/100g 85284-0001-01 | BLOOMWELL | 50 g | — | — | FDA listed | — |
| Topical Cream 4 g/100g 85284-0002-01 | BLOOMWELL | 50 g | — | — | Discontinued | — |
| Numbing Cream 4 g/100g 85284-0003-01 | BLOOMWELL | 50 g | — | — | Discontinued | — |
| numbing cream MAXIMUM STRENGTH 4 g/100g 85284-0006-01 | BLOOMWELL | 50 g | — | — | Discontinued | — |
| Veiurkiu External Analgesic Cream 4 g/100g 85284-0011-01 | BLOOMWELL | 50 g | — | — | FDA listed | — |
| Numbing Cream 40 mg/g 85569-0001-01 | 100 | 50 g | — | — | FDA listed | — |
| Numbing Cream 4 mg/100mL 85569-0002-01 | 100 | 50 ml | — | — | FDA listed | — |
| SCHOELIF Numbing Cream 4 g/100g 85817-0001-01 | Guangzhou | 50 g | — | — | FDA listed | — |
| Aouiv 4% Lidocaine Numbing Cream 4 g/100g 85817-0003-01 | Guangzhou | 60 g | — | — | FDA listed | — |
| Numbing Creams 4 g/100g 85881-0001-01 | Yongchun | 50 g | — | — | FDA listed | — |
| Black Cobra 4% Lidocaine Numbing Cream 40 mg/g 85924-0001-02 | BLACKCOBRASUPPLY, | 1 tube | — | — | Discontinued | — |
| Swiftalyn Numbing Cream 4 g/100g 87013-0002-01 | GENUINE | 50 g | — | — | FDA listed | — |
| Morovan 4 g/100g 87800-2624-01 | HONG | 1 can | — | — | FDA listed | — |
| Hempvana Ultra Strength Pain Relief Cream 4 g/100g 73287-0016-01 | Telebrands | 1 jar | — | — | FDA listed | — |
| Numbsure LIDOCAINE 4 g/100g 83714-0003-01 | Hambli | 1 tube | — | — | FDA listed | — |
| Hempvana Ultra Strength Pain Relief Cream Platinum 4% Lidocaine 4 g/100g 73287-0042-01 | Telebrands | 1 jar | — | — | FDA listed | — |
| Lubricaine 4 g/100g 63135-0727-04 | ESBA | 113 g | — | — | FDA listed | — |
| Topicaine 4 g/100g 63135-0312-04 | ESBA | 113 g | — | — | Discontinued | — |
| Recovery Numb 4 g/100g 49436-0099-30 | PURKLENZ | 30 g | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2022
On the market since
Mar 2022
📍
2026
Currently FDA-listed
4 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🗺️ Medicaid utilization & spend
📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 00536-1357-95, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q4 2025 · 4 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
13.4K
Units reimbursed last 4 qtrs
520.8K
Gross reimbursed last 4 qtrs
$320.4K
Avg / prescription
$23.82
Avg / unit
$0.6152
Latest quarter Q4 2025
4.3KRx
Medicaid pays / g
$0.6152
gross reimbursed
vs
NADAC / g
$0.4096
acquisition cost
=
Spread
+$0.2056
+50% vs cost
What Medicaid paid per g (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
Fee-for-service · 8,306 Rx Managed care · 5,143 Rx
State Medicaid map
Units reimbursed · per 100k residents
3.8899
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
Prescriptions—
Units—
Reimbursed—
🏆 Top states by units · per 100k residents
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Rugby Lidocaine (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 45%
Female · 54%
Unknown · 1%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 00536-1357-95 You're viewing this | 1 TUBE in 1 BOX (0536-1357-95) / 28 g in 1 TUBE | 2022-03-02 | Active |
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses Helps relieve the pain, itching, and burning associated with hemorrhoids and other anorectal disorders.
⏱️ Dosage and Administration ▾
When practical, cleanse the area with mild soap and warm water and rinse thoroughly. Gently dry by patting or blotting with toilet tissue or a soft cloth before applying. Adults and children 12 years and older: apply externally to the affected area up to 6 times a day. Children under 12 years of age: consult a doctor.
⚠️ Warnings ▾
For external use only. When using this product avoid contact with eyes, do not exceed recommended dosage unless directed by a doctor, do not put this product into the rectum by using fingers or any mechanical device or applicator. Stop use and ask a doctor if rectal bleeding occurs, condition worsens or does not improve within 7 days, allergic reaction occurs to ingredients in this product, symptom being treated does not subside or if redness, irritation, swelling, pain or other symptoms develop or increase, or symptoms clear up and return within a few days.
🧪 Active Ingredient ▾
Lidocaine 4%
🧪 Inactive Ingredients ▾
Butylated Hydroxytoluene, Cetostearyl Alcohol, Citric Acid, Edetate Disodium, Light Mineral Oil, Methylparaben, Polyoxyl 20 Cetostearyl Ether, Propylene Glycol, Propylparaben, Purified Water, Sodium Citrate, White Petrolatum.
🎯 Purpose ▾
Local Anesthetic
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.