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Lidocaine

Lidocaine is a numbing medicine (local anesthetic) used in injections given by clinicians for procedures and in many skin products for pain, itching, hemorrhoid discomfort and male genital desensitization.

Brand names XylocaineAktenLidodermZingoSolarcaine +11 more
Drug classes Amide Local Anesthetic
Rx/OTC Forms 7
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 1,020 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

Other forms & routes:
Transdermal
Lidocaine at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Lidocaine is a numbing medicine (local anesthetic) that blocks the signals nerves use to carry pain, given by clinicians as injections for procedures and in skin creams, gels, sprays and patches for pain, itching and hemorrhoid discomfort; a long-familiar standby, it has been on the U.S. market for decades and is widely available generically. On the skin it is usually very well tolerated, and what most people notice is mild redness or itching where it was applied. The serious signs to know are a severe allergic reaction or blue or gray skin, which points to methemoglobinemia (a blood problem that limits oxygen) and can appear hours later.

Clinical pearls

  • Never put a heating pad or tight bandage over a lidocaine patch, because heat pushes more medicine into the body.
  • Fold used patches sticky side in before discarding, since they still hold enough medicine to harm a chewing child or pet.
  • Do not layer a patch with other numbing creams, sprays or pain rubs, because the lidocaine absorbed from every product adds up.
  • Tell the clinician doing a procedure if you have G6PD deficiency, past methemoglobinemia, or heart or lung problems.
How we write & review this content — our editorial policy →
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾

WARNING: SUICIDAL THOUGHTS AND BEHAVIORS WARNING: SUICIDAL THOUGHTS AND BEHAVIORS See full prescribing information for complete boxed warning. Increased risk of suicidal thinking and behavior in children, adolescents, and young adults taking antidepressants ( 5.1 ) Monitor for worsening and emergence of suicidal thoughts and behaviors ( 5.1 ) Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. These studies did no...

Read the full warning on DailyMed →
How you get itPrescription and over the counter
Comes asTopical cream, ointment or gel, Skin patch, Injection +4
Earliest FDA record1948
Companies listing it with the FDA406
FDA label last updatedNov 1, 2024
FDA’s strongest warning (boxed)Yes, read the warning

Patient information guide A plain-language walkthrough of Lidocaine, written from its FDA label.

What Lidocaine is used for

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Lidocaine is used across many products, and each product has its own approved uses.

  • Accucaine (injection): local or regional anesthesia by infiltration, nerve blocks, and epidural blocks.
  • Patches (Lidocore and others): temporary relief of pain.
  • Lidocaine Pain Relief Gel-Patch: muscle soreness and minor joint pain.
  • Lidocaine Hydrochloride cream: itching, eczema, abrasions, minor burns, insect bites, and discomfort from hemorrhoids, anal fissures and similar conditions.
  • Lidotral, LidoPlus Pain Relief, Lidogel and RadiaGuard products: pain and itching from minor burns, sunburn, cuts, scrapes, insect bites and minor skin irritation.
  • The Solution Numbing gel: discomfort and itching in the perianal area, including hemorrhoids and other anorectal disorders.
  • Dynamo Delay, INTIMALE and SKINS DELAY: male genital desensitization to help slow ejaculation.

How Lidocaine works

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Lidocaine stabilizes the membrane of nerve cells. It blocks the ion movement that nerves need to start and carry impulses. This produces a local anesthetic (numbing) effect.

Lidocaine dosage

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Directions differ by product. Injections are given by clinicians, and the amount depends on the procedure and the person. Patches, gels, creams and sprays go on the skin, usually limited to a few uses per day. Many labels say to clean the skin first, wash hands after, and ask a doctor before using on young children.

  • Follow your prescriber and the product label.
  • Do not use more than the label allows.
  • The label evidence does not give missed-dose guidance.

Dosing details from the FDA-approved label

From the Lidocaine prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Lidocaine Hydrochloride Injection, epidural anesthesia (dosage varies with number of dermatomes)
    • Generally 2−3 mL of the indicated concentration per dermatome
    • Dosages should be reduced for children, elderly and debilitated patients, and patients with cardiac and/or liver disease
  • Caudal and lumbar epidural block test dose
    • A test dose such as 2−3 mL of 1.5% lidocaine hydrochloride, administered at least 5 minutes prior to injecting the total volume required
  • Normal healthy adults, with epinephrine
    • Individual maximum recommended dose should not exceed 7 mg/kg (3.5 mg/lb) of body weight
    • Maximum: in general maximum total dose not to exceed 500 mg
  • Normal healthy adults, without epinephrine
    • Maximum individual dose should not exceed 4.5 mg/kg (2 mg/lb) of body weight
    • Maximum: in general maximum total dose does not exceed 300 mg
  • Paracervical block (obstetrical and non-obstetrical patients)
    • One-half of the total dose is usually administered to each side
    • Inject slowly, five minutes between sides
    • Maximum: 200 mg total per 90 minute period
  • Intravenous regional anesthesia, adults
    • Only the 50 mL single-dose vial containing 0.5% Lidocaine Hydrochloride Injection, USP should be used
    • Maximum: should not exceed 4 mg/kg
  • Children over 3 years of age with normal lean body mass (example: child of 5 years weighing 50 lbs.)
    • Dose of lidocaine HCl should not exceed 75 — 100 mg (1.5 — 2 mg/lb)
    • Maximum dose is determined by the child's age and weight
  • Induction of intravenous regional anesthesia in children
    • Even more dilute solutions (i.e., 0.25 — 0.5%)
    • Maximum: total dosages not to exceed 3 mg/kg (1.4 mg/lb)
  • Aspercreme patch, adults and children 12 years of age and older
    • Apply to the affected area not more than 3 to 4 times daily
    • Use 1 patch at a time
    • Maximum: not more than 3 to 4 times daily
    • Children under 12 years of age: ask a doctor
  • Lidotral 2% Spray, adults and children 4 years of age and older
    • Spray to the affected area(s) two or three times daily or as directed by a licensed healthcare practitioner
    • Smaller areas of treatment recommended in a debilitated patient or a patient with impaired elimination; children under 4 years: consult a licensed healthcare practitioner
Read the label’s full dosing text

2 DOSAGE AND ADMINISTRATION DOSAGE AND ADMINISTRATION • Take duloxetine delayed-release capsules once daily, with or without food. Swallow whole; do not crush, chew, or open capsule. ( 2.1 ) Indication Starting Dose Target Dose Maximum Dose MDD ( 2.2 ) 40 mg/day to 60 mg/day Acute Treatment: 40 mg/day (20 mg twice daily) to 60 mg/day (once daily or as 30 mg twice daily); Maintenance Treatment: 60 mg/day 120 mg/day GAD ( 2.3 ) Adults Geriatric Pediatrics (7 to 17 years of age) 60 mg/day 30 mg/day 30 mg/day 60 mg/day (once daily) 60 mg/day (once daily) 30 to 60 mg/day (once daily) 120 mg/day 120 mg/day 120 mg/day DPNP ( 2.4 ) 60 mg/day 60 mg/day (once daily) 60 mg/day FM ( 2.5 ) Adults 30 mg/day 60 mg/day (once daily) 60 mg/day Chronic Musculoskeletal Pain ( 2.6 ) 30 mg/day 60 mg/day (once daily) 60 mg/day Discontinuing duloxetine delayed-release capsules: Gradually reduce dosage to avoid discontinuation symptoms ( 2.8 , 5.7 ) 2.1 Important Administration Instructions Administer duloxetine delayed-release capsules orally (with or without meals) and swallow whole. Do not chew or crush, and do not open the delayed-release capsule and sprinkle its contents on food or mix with liquids because these actions might affect the enteric coating. If a dose of duloxetine delayed-release capsules is missed, take the missed dose as soon as it is remembered. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time. Do not take two doses of duloxetine delayed-release capsules at the same time. 2.2 Dosage for Treatment of Major Depressive Disorder in Adults The recommended starting dosage in adults with MDD is 40 mg/day (given as 20 mg twice daily) to 60 mg/day (given either once daily or as 30 mg twice daily). For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to duloxetine delayed- release capsules before increasing to 60 mg once daily. While a 120 mg/day dose was shown to be effective, there is no evidence that doses greater than 60 mg/day confer any additional benefits. Periodically reassess to determine the need for maintenance treatment and the appropriate dosage for such treatment.

Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →

Lidocaine side effects

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Skin products can cause local reactions at the application site.

Common side effects

  • Skin redness or irritation where applied
  • Rash or itching at the application site
  • Pain or swelling at the application site
  • Blistering of the skin (stop use if it happens)

When to get medical help

  • Get emergency help right away for signs of a severe allergic reaction after lidocaine.
  • Call your doctor if blue or gray skin discoloration appears. This can be a sign of methemoglobinemia (a blood problem that limits oxygen). It can start right away or hours later.
  • Stop a skin product and ask a doctor if a rash, swelling, blistering or worsening irritation develops.
  • Stop a skin product and ask a doctor if your condition worsens or symptoms last more than 7 days (for pain patches).
  • If a child or pet chews or swallows a patch (new or used), get medical help or contact Poison Control right away.

Stop the product and ask a doctor if these occur. Get urgent help for allergic reactions, bluish skin color, or any suspected overdose.

Lidocaine warnings and precautions

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  • Injection safety: lidocaine injections for infiltration and nerve block should be used only by clinicians prepared to manage toxic reactions. Delays in management can lead to acidosis, cardiac arrest and possibly death.
  • Methemoglobinemia: a blood condition that can cause blue or gray skin and may start hours later. It can cause seizures, coma, arrhythmias and death if not treated.
  • Chondrolysis: infusing local anesthetics into joints after surgery is not an approved use and has been linked to cartilage damage.
  • Allergic reactions: anaphylaxis can occur. Stop the drug in a severe reaction.
  • Skin products: for external use only. Avoid eyes, mucous membranes, rashes, wounds and damaged skin where the label says so. Avoid tight bandaging and heat over patches.
  • Used patches still contain medicine and can be dangerous to children and pets.

Lidocaine interactions

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The label points to these cautions.

  • Heat (heating pads) over a patch: raises how much lidocaine is absorbed.
  • Other topical analgesics: do not use at the same time as a lidocaine patch (Pro Comfort 8 Hours Patch label).
  • Other local anesthetic products: the total absorbed amount from all products must be considered (Lidotral).
  • Oxidizing agents: increase the risk of methemoglobinemia.
  • CNS stimulants and depressants, and acidosis: change the lidocaine level that causes whole-body effects.

Interactions listed in the FDA-approved label

From the Lidocaine prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Potent inhibitors of CYP1A2 (e.g., fluvoxamine, cimetidine, ciprofloxacin, enoxacin): Duloxetine AUC increased approximately 6-fold, Cmax about 2.5-fold, and t1/2 approximately 3-fold with fluvoxamine 100 mg. Potent inhibitors of CYP1A2 should be avoided
  • Potent CYP2D6 inhibitors (paroxetine, fluoxetine, quinidine): Paroxetine 20 mg once daily increased duloxetine AUC by about 60%; greater inhibition expected with higher paroxetine doses.
  • Dual inhibition of CYP1A2 and CYP2D6: Duloxetine 40 mg twice daily with fluvoxamine 100 mg in CYP2D6 poor metabolizers resulted in a 6-fold increase in duloxetine AUC and Cmax.
  • NSAIDs, aspirin, and warfarin (drugs that interfere with hemostasis): Concurrent use of an NSAID or aspirin may potentiate the risk of upper gastrointestinal bleeding; altered anticoagulant effects, including increased bleeding, reported with SSRIs or SNRIs and warfarin. Patients receiving warfarin therapy should be carefully monitored when duloxetine is initiated or discontinued
  • Lorazepam: The pharmacokinetics of duloxetine were not affected by co-administration.
  • Temazepam: The pharmacokinetics of duloxetine were not affected by co-administration.
  • Drugs that affect gastric acidity: Aluminum- and magnesium-containing antacids or famotidine had no significant effect on duloxetine absorption; unknown whether proton pump inhibitors affect absorption. Caution in patients with conditions that may slow gastric emptying
  • Drugs metabolized by CYP1A2 (theophylline, caffeine): Duloxetine does not induce CYP1A2; theophylline AUC increased 7% and 20% in two clinical studies.
  • Drugs metabolized by CYP2D6 (desipramine): Duloxetine is a moderate inhibitor of CYP2D6; desipramine AUC increased 3-fold.
  • Alcohol: Duloxetine did not increase the impairment of mental and motor skills caused by alcohol; liver injury cases had substantial intercurrent ethanol use.
Read the label’s full interactions text

7 DRUG INTERACTIONS Potent inhibitors of CYP1A2 should be avoided ( 7.1 ) Potent inhibitors of CYP2D6 may increase duloxetine concentrations ( 7.2 ) Duloxetine is a moderate inhibitor of CYP2D6 ( 7.9 ) Both CYP1A2 and CYP2D6 are responsible for duloxetine metabolism. 7.1 Inhibitors of CYP1A2 When duloxetine 60 mg was co-administered with fluvoxamine 100 mg, a potent CYP1A2 inhibitor, to male subjects (n=14) duloxetine AUC was increased approximately 6-fold, the C max was increased about 2.5-fold, and duloxetine t 1/2 was increased approximately 3-fold. Other drugs that inhibit CYP1A2 metabolism include cimetidine and quinolone antimicrobials such as ciprofloxacin and enoxacin [see Warnings and Precautions ( 5.12 )] . 7.2 Inhibitors of CYP2D6 Concomitant use of duloxetine (40 mg once daily) with paroxetine (20 mg once daily) increased the concentration of duloxetine AUC by about 60%, and greater degrees of inhibition are expected with higher doses of paroxetine. Similar effects would be expected with other potent CYP2D6 inhibitors (e.g., fluoxetine, quinidine) [see Warnings and Precautions ( 5.12 )] . 7.3 Dual Inhibition of CYP1A2 and CYP2D6 Concomitant administration of duloxetine 40 mg twice daily with fluvoxamine 100 mg, a potent CYP1A2 inhibitor, to CYP2D6 poor metabolizer subjects (n=14) resulted in a 6-fold increase in duloxetine AUC and C max . 7.4 Drugs that Interfere with Hemostasis (e.g., NSAIDs, Aspirin, and Warfarin) Serotonin release by platelets plays an important role in hemostasis. Epidemiological studies of the case-control and cohort design that have demonstrated an association between use of psychotropic drugs that interfere with serotonin reuptake and the occurrence of upper gastrointestinal bleeding have also shown that concurrent use of an NSAID or aspirin may potentiate this risk of bleeding. Altered anticoagulant effects, including increased bleeding, have been reported when SSRIs or SNRIs are co-administered with warfarin.

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

Check Lidocaine against a supplement or herb →

Before taking Lidocaine

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  • Do not use if you are allergic to lidocaine or any ingredient in the product.
  • Ask before use if you have G6PD deficiency, methemoglobinemia, or heart or lung problems.
  • Infants under 6 months are more susceptible to methemoglobinemia.
  • Liver problems can lengthen how long lidocaine stays in the body (half-life may double or more).
  • Kidney problems may let breakdown products build up.
  • If pregnant or breastfeeding, ask a health professional before using Lidocore patches.
  • Age limits for children differ by product. Ask a doctor for young children.

Lidocaine overdose

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Too much lidocaine is most often caused by high blood levels, or by accidental injection into the spinal fluid. This can cause convulsions, breathing problems, low blood pressure, slow or irregular heartbeat and cardiac arrest. Treatment includes oxygen, breathing support and circulation support, and anti-seizure medicine if needed. Dialysis is of negligible value. If a child or pet swallows a patch, get medical help or call Poison Control right away.

What Lidocaine does in the body

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Lidocaine blocks nerve signals and numbs the treated area. Excessive blood levels can change cardiac output, blood vessel resistance and blood pressure. At recommended doses the usual net effect is a modest drop in blood pressure. Side effects become more apparent as blood levels rise above a certain threshold.

How your body processes Lidocaine

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Lidocaine is completely absorbed after injection. The rate depends on the injection site and whether a vasoconstrictor is present. With skin systems, absorption depends on how long the product is on and how much skin it covers. Heat can raise absorption. The liver breaks lidocaine down quickly and the kidneys remove it. Less than 10% leaves unchanged. The half-life after an intravenous dose is about 1.5 to 2 hours. It may be doubled or more in liver dysfunction.

How to store Lidocaine

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Store at 20° to 25°C (68° to 77°F); excursions permitted between 15° to 30°C (59° to 86°F) .

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

Lidocaine: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Lidocaine — the kind of thing our pharmacy team would talk through with you at the counter.

What is lidocaine used for?

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Lidocaine numbs the area where it is used. Clinicians inject it for procedures. Skin products are used for pain, itching, minor burns, insect bites, hemorrhoid discomfort, and in some sprays for male genital desensitization. Which use applies depends on the specific product.

How do I use a lidocaine patch or gel?

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Clean and dry the skin first, then apply as your product’s directions say. Wash your hands afterward. Don’t exceed the number of uses on the label. Ask a doctor before using a product on a child.

Can I use a heating pad with a lidocaine patch?

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No. Heat can increase how much lidocaine your body absorbs. Don’t bandage tightly either. Also avoid using other topical pain products at the same time.

What side effects should I watch for?

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Watch the skin for redness, rash, itching, irritation, pain, swelling or blistering. Stop the product and ask a doctor if these happen. Also stop if symptoms get worse or last more than 7 days.

How do I dispose of used patches?

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Dispose of them so children and pets can’t get to them. Used patches still contain medicine that can cause serious effects if chewed or swallowed. If that happens, get medical help or call Poison Control right away.

Is lidocaine safe in pregnancy or breastfeeding?

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For Lidocore patches, the label says to ask a health professional first if you are pregnant or breastfeeding. Check with me or your doctor before using any lidocaine product.

Is Lidocaine available over the counter?

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Both. Some Lidocaine products are sold over the counter and others need a prescription. According to their FDA listings, the topical cream, ointment or gel, skin patch, topical solution and topical spray forms are sold both ways, at different strengths or package sizes, the inhaler, rectal topical, ear drops and topical powder forms are sold over the counter and the injection, oral solution and eye ointment forms need a prescription. The package says which kind you have. Your pharmacist can tell you which product is right for you.

When was Lidocaine first available?

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The earliest FDA record we hold for Lidocaine is from 1948: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Lidocaine was first used.

Who makes Lidocaine?

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406 companies currently list Lidocaine products in the FDA's NDC Directory, including Veridian Healthcare, PureTek Corporation, HF Acquisition Co LLC, DBA HealthFirst. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Lidocaine on HelloPharmacist

🌿Drug & Supplement CheckerLidocaine vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Lidocaine NDCs & costs 🅰️Browse Drugs A–ZLook up any medication
Detailed data & references for Lidocaine Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Lidocaine forms and strengths (how it comes)

Lidocaine is available in 7 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Lidocaine inactive ingredients by manufacturer.

Topical cream, ointment or gel

On the skin
Brands Dr. Numb
How this form is used
What it may be used for
  • Lidocaine Hydrochloride cream is used for relief of itching, minor burns, insect bites, and discomfort from conditions such as hemorrhoids and anal fissures.
  • DermacinRx Lidotral cream is used for temporary relief of pain and itching from minor burns, sunburn, minor cuts, scrapes, insect bites and minor skin irritation.
Important instructions
  • Alocane Emergency Burn: clean the burn with mild soap and water, then apply gently. Children under 2 should see a doctor first. Do not use in large quantities over raw or blistered areas.
  • DCH Pain Relief cream: apply a thin layer and wash hands afterward. Ask a doctor before use in children under 12.
  • Hilook Blue Gel Anesthetic: apply to cleaned skin and massage gently. The label says to wait for it to take effect.
Available strengths 19 strengths
5 mg/g 8 mg/g 20 mg/g 20 mg/mL 30 mg/g 40 mg/g
Show 13 more strengths Show fewer strengths
40 mg/mL 41.2 mg/g 0.05 g/g 50 mg/g 50 mg/mL 0.5 g/100 g 2 g/100 g 4 g/80 g 4 g/100 g 4 g/100 mL 5 g/100 g 5 g/100 mL 5.05 g/g
602 FDA-listed product records ⓘ

Skin patch

On the skin · Through the skin
Brands Aspercreme Biofreeze Ultraflex Curist Lidocaine Patch Lidocaine Pain Relief Gel-Patch Lidocore Lidoderm
How this form is used
What it may be used for
  • Lidocore is used for temporary relief of pain.
  • Lidocaine Pain Relief Gel-Patch temporarily relieves muscle soreness and minor joint pain in areas such as the wrist, knees, back, neck, hips, shoulders and elbows.
Important instructions
  • Aspercreme patch: apply to clean, dry skin and wash hands after applying or removing. Children under 12 should ask a doctor.
  • Biofreeze Ultraflex: use one patch at a time and leave it in place for up to 8 hours.
  • Curist Lidocaine Patch: use one patch for up to 12 hours and discard after one use. Do not use in children under 12.
  • Lidocore: do not use on wounds or damaged skin or with a heating pad.
Available strengths 11 strengths
4 mg/100 mg 18 mg/116cm2 LIDOCAINE 18 mg/116cm2 0.04 g 0.04 g/g 40 mg
Show 5 more strengths Show fewer strengths
40 mg/g 50 mg/g 700 mg 4 g/100 g 4 g/1001
389 FDA-listed product records ⓘ

Injection

Infiltration · Into a vein · Into the epidural space · Intracaudal · Perineural
Brands Xylocaine
How this form is used
What it may be used for
  • Accucaine (lidocaine hydrochloride injection) is used for local or regional anesthesia, including infiltration, peripheral nerve blocks and epidural blocks.
Important instructions
  • Accucaine is given by trained clinicians. Volumes and strengths depend on the procedure and the patient.
  • Accucaine is not approved for infusion into joints after surgery. Chondrolysis (cartilage damage) has been reported.
Available strengths 4 strengths
5 mg/mL 10 mg/mL 15 mg/mL 20 mg/mL
344 FDA-listed product records ⓘ

Topical solution

By mouth · On the skin
Brands INTIMALE Maximum Strength Delay SKINS DELAY Maximum Strength Lidocaine
How this form is used
What it may be used for
  • INTIMALE Maximum Strength Delay and SKINS DELAY Maximum Strength Lidocaine are used for directions involving the penis to desensitize and delay ejaculation.
Important instructions
  • INTIMALE Maximum Strength Delay: apply shortly before intercourse and wash hands afterward. Use the minimum effective amount and do not exceed the label maximum.
  • SKINS DELAY Maximum Strength Lidocaine: massage in and wash hands after use. Wait to feel the full effect before applying more.
Available strengths 6 strengths
10 mg/mL 20 mg/mL 40 mg/mL 4 g/100 g 4 g/100 mL 4 g/mL
134 FDA-listed product records ⓘ

Topical spray

On the skin
Brands DCH Pain Relief Dynamo Delay Dynamo Delay Sample Bottle Lidotral Five Percent Lidotral Two Percent Solarcaine
How this form is used
What it may be used for
  • Dynamo Delay and Dynamo Delay Sample Bottle are used for temporary male genital desensitization, helping slow the onset of ejaculation.
  • Lidotral Two Percent and Lidotral Five Percent are used for temporary relief of pain and itching from minor burns, sunburn, minor cuts, scrapes, insect bites and minor skin irritation.
Important instructions
  • DCH Pain Relief spray: for adults and children 2 and older, apply to the affected area as limited on the label. Children under 2 should see a physician.
  • Lidotral Two Percent and Five Percent: spray on intact skin two or three times daily or as directed by a licensed healthcare practitioner.
  • Lidotral sprays: use smaller treated areas in debilitated patients or those with impaired elimination.
Available strengths 4 strengths
20 mg/mL 2 g/100 mL 4 g/100 mL 20 g/L
45 FDA-listed product records ⓘ

Oral solution

By mouth
Available strengths 2 strengths
20 mg/mL 40 mg/mL
9 FDA-listed product records ⓘ

Inhaler

On the skin
Available strengths 1 strength
0.64 g/127 g
4 FDA-listed product records ⓘ

Lidocaine on the U.S. market: products, makers and brands

How Lidocaine appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

406 companies list 1,142 Lidocaine product records with the FDA, mostly as topical cream, ointment or gel, skin patch, injection; the earliest marketing or approval year on record is 1948. Brand names on the directory include Xylocaine, Akten, Lidoderm and 13 more; the rest are generics.

7
Dose forms ⓘ
406
Labelers (makers, repackagers, distributors)
40
Brand names
1,142
FDA-listed product records ⓘ
1948
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (48) · Kit (37) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Veridian Healthcare3%
PureTek Corporation3%
HF Acquisition Co LLC, DBA HealthFirst2%
Medical Purchasing Solutions, LLC2%
Asclemed USA, Inc.2%
Bryant Ranch Prepack2%
Other makers87%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Lidocaine is used (Medicaid data)

A general measure of how commonly Lidocaine is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Lidocaine is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

3,379,243
Medicaid prescriptions filled (Q1–Q4 2025)
$233.6M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Lidocaine prescribed? Of the 1,601 medications we measure, Lidocaine ranks #62 by Medicaid prescriptions — more than 96% of them.

Where Lidocaine ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #62 of 1,601
#57 Clonazepam 3,602,972 Rx #58 Fluconazole 3,462,620 Rx #59 Polyethylene Glycol 33... 3,441,581 Rx #60 Doxycycline 3,416,939 Rx #61 Risperidone 3,411,596 Rx #62 Lidocaine 3,379,243 Rx #63 Budesonide / Formotero... 3,326,951 Rx #64 Meloxicam 3,321,801 Rx #65 Folic Acid 3,298,551 Rx #66 Metronidazole 3,247,421 Rx #67 Hydrochlorothiazide 3,216,975 Rx

Utilization by Lidocaine product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 0.05 mg/mg medicated patch is the most-dispensed Lidocaine product — about 42% of these Medicaid prescriptions.

lidocaine 0.05 MG/MG Medicated Patch Most dispensed

1,403,004 Medicaid prescriptions (Q1–Q4 2025) 42% of Lidocaine prescriptions shown $97.6M gross reimbursement (before rebates) ≈ $70 per prescription (gross)

Summed across the 9 of 137 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1745091

lidocaine 0.04 MG/MG Medicated Patch

621,230 Medicaid prescriptions (Q1–Q4 2025) 18% of Lidocaine prescriptions shown $20.7M gross reimbursement (before rebates) ≈ $33 per prescription (gross)

Summed across the 17 of 893 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737778

lidocaine hydrochloride 20 MG/ML Mucous Membrane Topical Solution

404,036 Medicaid prescriptions (Q1–Q4 2025) 12% of Lidocaine prescriptions shown $7.1M gross reimbursement (before rebates) ≈ $17 per prescription (gross)

Summed across the 7 of 54 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1010739

lidocaine 0.05 MG/MG Topical Ointment

247,271 Medicaid prescriptions (Q1–Q4 2025) 7% of Lidocaine prescriptions shown $6.3M gross reimbursement (before rebates) ≈ $26 per prescription (gross)

Summed across the 20 of 149 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1543069

lidocaine 0.018 MG/MG Medicated Patch

122,681 Medicaid prescriptions (Q1–Q4 2025) 4% of Lidocaine prescriptions shown $67.5M gross reimbursement (before rebates) ≈ $550 per prescription (gross)

Summed across the 1 of 3 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2001434

lidocaine hydrochloride 10 MG/ML Injectable Solution

98,669 Medicaid prescriptions (Q1–Q4 2025) 3% of Lidocaine prescriptions shown $4.7M gross reimbursement (before rebates) ≈ $47 per prescription (gross)

Summed across the 21 of 102 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1010033

5 ML lidocaine hydrochloride 20 MG/ML Injection

97,804 Medicaid prescriptions (Q1–Q4 2025) 3% of Lidocaine prescriptions shown $7.6M gross reimbursement (before rebates) ≈ $78 per prescription (gross)

Summed across the 14 of 68 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737761

lidocaine 40 MG/ML Topical Cream

66,342 Medicaid prescriptions (Q1–Q4 2025) 2% of Lidocaine prescriptions shown $2M gross reimbursement (before rebates) ≈ $30 per prescription (gross)

Summed across the 8 of 125 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1421893

5 ML lidocaine hydrochloride 10 MG/ML Injection

60,565 Medicaid prescriptions (Q1–Q4 2025) 2% of Lidocaine prescriptions shown $4.6M gross reimbursement (before rebates) ≈ $76 per prescription (gross)

Summed across the 15 of 66 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737566

lidocaine hydrochloride 20 MG/ML Injectable Solution

45,652 Medicaid prescriptions (Q1–Q4 2025) 1% of Lidocaine prescriptions shown $3.2M gross reimbursement (before rebates) ≈ $71 per prescription (gross)

Summed across the 16 of 87 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1010671

lidocaine hydrochloride 30 MG/ML Topical Cream

44,257 Medicaid prescriptions (Q1–Q4 2025) 1% of Lidocaine prescriptions shown $1.9M gross reimbursement (before rebates) ≈ $43 per prescription (gross)

Summed across the 6 of 11 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1010835

30 ML lidocaine hydrochloride 10 MG/ML Injection

25,595 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $1.2M gross reimbursement (before rebates) ≈ $45 per prescription (gross)

Summed across the 6 of 27 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737562

lidocaine hydrochloride 0.02 MG/MG Topical Gel

23,374 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $1.4M gross reimbursement (before rebates) ≈ $61 per prescription (gross)

Summed across the 7 of 99 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1011852

2 ML lidocaine hydrochloride 10 MG/ML Injection

23,335 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $1.3M gross reimbursement (before rebates) ≈ $54 per prescription (gross)

Summed across the 10 of 44 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737568

5 ML lidocaine hydrochloride 20 MG/ML Prefilled Syringe

21,113 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $2M gross reimbursement (before rebates) ≈ $95 per prescription (gross)

Summed across the 2 of 20 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1012068

lidocaine hydrochloride 40 MG/ML Topical Cream

18,433 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $201,915 gross reimbursement (before rebates) ≈ $11 per prescription (gross)

Summed across the 2 of 98 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1010895

2 ML lidocaine hydrochloride 20 MG/ML Injection

12,688 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $638,448 gross reimbursement (before rebates) ≈ $50 per prescription (gross)

Summed across the 8 of 34 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737757

lidocaine hydrochloride 40 MG/ML Mucous Membrane Topical Solution

5,839 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $177,928 gross reimbursement (before rebates) ≈ $30 per prescription (gross)

Summed across the 6 of 23 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1010878

10 ML lidocaine hydrochloride 20 MG/ML Injection

3,707 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $727,078 gross reimbursement (before rebates) ≈ $196 per prescription (gross)

Summed across the 2 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737763

lidocaine 50 MG/ML Rectal Cream

3,608 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $98,183 gross reimbursement (before rebates) ≈ $27 per prescription (gross)

Summed across the 3 of 112 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1366789

50 ML lidocaine hydrochloride 5 MG/ML Injection

1,679 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $99,595 gross reimbursement (before rebates) ≈ $59 per prescription (gross)

Summed across the 2 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737343

500 ML lidocaine hydrochloride 4 MG/ML Injection

1,314 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $2,036 gross reimbursement (before rebates) ≈ $1.55 per prescription (gross)

Summed across the 2 of 3 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737744

5 ML lidocaine hydrochloride 40 MG/ML Injection

856 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $114,486 gross reimbursement (before rebates) ≈ $134 per prescription (gross)

Summed across the 1 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1010844

10 ML lidocaine hydrochloride 10 MG/ML Injection

822 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $95,577 gross reimbursement (before rebates) ≈ $116 per prescription (gross)

Summed across the 1 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737570

lidocaine hydrochloride 0.028 MG/MG Topical Gel

487 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $755,502 gross reimbursement (before rebates) ≈ $1,551 per prescription (gross)

Summed across the 1 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2562183

lidocaine hydrochloride 38.8 MG/ML Topical Cream

341 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $303,824 gross reimbursement (before rebates) ≈ $891 per prescription (gross)

Summed across the 1 of 4 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1723991

250 ML lidocaine hydrochloride 8 MG/ML Injection

279 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $2,130 gross reimbursement (before rebates) ≈ $7.63 per prescription (gross)

Summed across the 2 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737723

lidocaine hydrochloride 5 MG/ML Injectable Solution

103 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $1,033 gross reimbursement (before rebates) ≈ $10 per prescription (gross)

Summed across the 1 of 6 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1010900

lidocaine hydrochloride 0.035 MG/MG Ophthalmic Gel

90 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown

Summed across the 1 of 4 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1009462

5 ML lidocaine hydrochloride 10 MG/ML Prefilled Syringe

79 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $6,597 gross reimbursement (before rebates) ≈ $84 per prescription (gross)

Summed across the 1 of 12 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1012066

250 ML lidocaine hydrochloride 4 MG/ML Injection

13 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $29 gross reimbursement (before rebates) ≈ $2.24 per prescription (gross)

Summed across the 1 of 3 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737742

20 ML lidocaine hydrochloride 15 MG/ML Injection

11 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $10 gross reimbursement (before rebates) ≈ $0.87 per prescription (gross)

Summed across the 1 of 4 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1737636

Other Lidocaine products — combination packs and listings not yet matched to a specific clinical product (kept visible so every prescription is accounted for)

23,966 Medicaid prescriptions (Q1–Q4 2025) <1% of Lidocaine prescriptions shown $1.5M gross reimbursement (before rebates) ≈ $62 per prescription (gross)

Summed across the 12 of 610 listed NDC products with Medicaid activity.

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Lidocaine, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 207 of 2,837 listed Lidocaine NDCs with Medicaid activity.

Compare Lidocaine products

A representative set of FDA-listed product records for Lidocaine — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 126 of 1,142 products — FDA National Drug Code Directory. See every product, package size and price: browse all 1,142 Lidocaine NDCs →

Lidocaine recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list 10 Lidocaine recalls since July 2021, covering 14 product listings. Seven of them are still ongoing or began in the last six months and are listed first. A recall names specific lots from one company, so check the lot number on your own bottle rather than assuming every product is affected; your pharmacist can check whether your supply came from an affected lot.

Ongoing Class II Jul 16, 2026 · Fresenius Kabi USA, LLC
Presence of Particulate Matter: Hair was found in products
  • Lidocaine HCl Injection, USP, 2%, 100 mg per 5 mL (20 mg per mL), 25 Single Dose Vials, 5 mL per vial, Rx only, Sterile, Fresenius Kabi, Lake Zurich, IL 60047 NDC Tray: 63323-208-05; NDC Vial: 63323-… Lots: Lot #: 6133801, Exp. Date 01/2028 FDA record D-0726-2026 →
Ongoing Class II Jun 8, 2026 · Asclemed USA Inc.
Lack of Assurance of Sterility
  • Lidocaine HCl Injection USP, 1% (10 mg/mL), 5 mL single dose ampule, Rx Only, Distributed by Enovachem Pharmaceuticals, Torrance, CA 90501, NDC: 85766-187-01. Lots: Lot #: AE3102, 031926L01, 032026A01, Exp 11/30/2026; AE5052, 052026G01, Exp 04/30/2028. FDA record D-0659-2026 →
  • Accucaine, Kit contains: Lidocaine HCl Injection USP, 1% (10 mg/mL), 5 mL single dose ampule, Rx Only, Distributed by Enovachem Pharmaceuticals, Torrance, CA 90501, NDC: 76420-715-01. Lots: Lot #: AE3102, 121924X2, 022525X4, 033125X1, 030426X2, 033125X2, 041725X3, 061225X1, 072225X3, 080525X6, 080525X7, 080525X8, 091225X1, 100225X2, 100625X1, 122225X4, 010626X3, 041326X4, Exp 11/30/2026; AE5052, 041426X2, 041726X1, 051826X2,… FDA record D-0658-2026 →
Ongoing Class II May 12, 2026 · Spectra Medical Devices, Llc
Lack of Assurance of Sterility
  • Lidocaine HCl Injection USP, 25x5 mL, Single-Dose Ampules, Rx Only, Distributed by: Spectra Medical Devices, LLC, Wilmington, Made in S. Korea, NDC 65282-1605-1. Lots: Lot#: AE4013, Exp 1/31/2027; AE5032 & AE5039, Exp 3/31/2028; AE5104, Exp 8/31/2028. FDA record D-0554-2026 →
Ongoing Class II Apr 2, 2026 · Huons Co., Ltd.
Lack of Assurance of Sterility
  • Lidocaine HCl Injection, USP, 2%, 100 mg/5mL (20 mg/mL), 5 mL Single-Dose Vials, Rx only, Manufactured by: Huons Co., Ltd., 100 Bio valley-ro, Jecheon-si, Chungchengbuk-do, Korea, NDC 73293-0003-1 (v… Lots: All lots within expiry FDA record D-0532-2026 →
  • Lidocaine HCl injection, USP, 1% 50mg/5mL (10 mg/mL), 5 mL Single Dose Vials, Rx only, Manufactured by: Huons Co, Ltd, Chungcheongbuk-do, Korea NDC 73293-0001-1 (vial), NDC 73293-0001-2 (10 count car… Lots: All lots within expiry FDA record D-0529-2026 →
Ongoing Class III Apr 20, 2023 · Bryant Ranch Prepack, Inc.
Labeling: Typographical error on the upper left-hand side of the box and individual patch label that has the incorrect dosage form stating, each tablet contains instead of each adhesive patch contains.
  • Lidocaine Patch 5%, 1 patch (63629-8755-20) packaged in 30-count patches per carton (63629-8755-1), Rx only, each patch contains: 700 mg (50mg per gram adhesive) in an aqueous base, Manufactured by:… Lots: Lot: 204603, Exp: 09/30/2024; Lots:208608, 208749, 208445, 209101, 208609, 208295, 209106, 209102, 209212, 208975, 209211, 209706, 209779, 209624, 209839, 209548, Exp: 12/31/2024; Lots: 204604, 204601, 204550, 204599, 204871, 204555, 20561… FDA record D-0556-2023 →
Ongoing Class II Nov 30, 2021 · Teligent Pharma, Inc.
Superpotent Drug: Minimally superpotent
  • Lidocaine Hydrochloride, Topical Solution USP, 4% (40 mg/mL), packaged in 50 mL screw cap bottles, Rx Only, Manufactured by Teligent Pharma, Inc., Buena, NJ 08310, Distributed by: McKesson Corporatio… Lots: Lot #: 15594, Exp Date 05/2023 FDA record D-0296-2022 →
Ongoing Class I Nov 30, 2021 · Teligent Pharma, Inc.
Superpotent Drug
  • Lidocaine Hydrochloride, Topical Solution USP, 4% (40 mg/mL), packaged in 50 mL screw cap bottles, Rx Only, Manufactured by Teligent Pharma, Inc., Buena, NJ 08310, Distributed by: McKesson Corporatio… Lots: Lot #: 16345, Exp. Date 01/2024 FDA record D-0295-2022 →
Class II Oct 24, 2024 · Terminated · Unexo Life Sciences Private Limited
cGMP Deviations
  • EQUATE MAXIMUM STRENGTH LIDOCAINE PAIN RELIEVING PATCH Lidocaine 4% Topical Anesthetic, 6 patches per box PATCHES, LIDOCAINE 4%, Distributed by: Walmart Inc., Bentonville, AR 72716 NDC 79903-106-06 Lots: UPC 6 81131 07127 7 FDA record D-0068-2025 →
  • THERACARE MAXIMUM STRENGTH PAIN RELIEF 4% LIDOCAINE PATCH, a) 1 patch (NDC 71101-001-24, UPC 8 45717 00878 5) and b) 6 patches (NDC 71101-001-06, UPC 8 45717 01056 6), Manufactured for: Veridian Heal… Lots: a) UPC 8 45717 00878 5 b) UPC 8 45717 01056 6 FDA record D-0065-2025 →
Class II Apr 13, 2022 · Terminated · Mckesson Medical-Surgical Inc. Corporate Office
cGMP deviations: Temperature abuse
  • Lidocaine Patch 5%, 30-count box, Rx only, MFG: Teva Pharma USA, NDC 0591-3525-30 Lots: McKesson Medical-Surgical (MMS) is not able to identify the particular lot number received by a particular consignee for the recalled prescription products. Each letter includes the date it was distributed to customers and the dates that i… FDA record D-1068-2022 →
  • Lidocaine Patch 5%, 30-count carton, Rx only, MFG: Qualitest Products, NDC 0603-1880-16 Lots: McKesson Medical-Surgical (MMS) is not able to identify the particular lot number received by a particular consignee for the recalled prescription products. Each letter includes the date it was distributed to customers and the dates that i… FDA record D-1043-2022 →
Class II Oct 12, 2021 · Terminated · Teligent Pharma, Inc.
CGMP Deviations: Lots recalled because they were manufactured at the same facility using the same components as the products that had cracked seals in caps that were found to be superpotent.
  • Lidocaine Hydrochloride Topical Solution USP 4% (40 mg/mL), 50 mL glass bottles, Rx Only, Manufactured by: Teligent Pharma Inc., Buena, NJ 06310, Distributed by: McKesson Corporation dba Sky Packagin… Lots: Lot #: 16306, Exp. Date 01/2024. FDA record D-0279-2022 →

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Lidocaine RxCUI 6387 22 dose forms · 104 strengths
  1. Dose form (SCDF) Injectable Solution RxCUI 372599 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 1 MG/ML RxCUI 1010694 hydrochloride 10 MG/ML RxCUI 1010033 hydrochloride 2 MG/ML RxCUI 1012019 hydrochloride 20 MG/ML RxCUI 1010671 hydrochloride 5 MG/ML RxCUI 1010900 hydrochloride 6 MG/ML RxCUI 1013004
  2. Dose form (SCDF) Injection RxCUI 1737342 In current FDA listings
    Clinical drug / strength (SCD) 2 ML lidocaine hydrochloride 10 MG/ML RxCUI 1737568 2 ML lidocaine hydrochloride 20 MG/ML RxCUI 1737757 2 ML lidocaine hydrochloride 50 MG/ML RxCUI 1011093 5 ML lidocaine hydrochloride 10 MG/ML RxCUI 1737566 5 ML lidocaine hydrochloride 20 MG/ML RxCUI 1737761 5 ML lidocaine hydrochloride 40 MG/ML RxCUI 1010844 10 ML lidocaine hydrochloride 10 MG/ML RxCUI 1737570 10 ML lidocaine hydrochloride 15 MG/ML RxCUI 1737640 10 ML lidocaine hydrochloride 20 MG/ML RxCUI 1737763 20 ML lidocaine hydrochloride 15 MG/ML RxCUI 1737636 30 ML lidocaine hydrochloride 10 MG/ML RxCUI 1737562 50 ML lidocaine hydrochloride 5 MG/ML RxCUI 1737343 250 ML lidocaine hydrochloride 4 MG/ML RxCUI 1737742 250 ML lidocaine hydrochloride 8 MG/ML RxCUI 1737723 500 ML lidocaine hydrochloride 4 MG/ML RxCUI 1737744 500 ML lidocaine hydrochloride 8 MG/ML RxCUI 1737735
  3. Dose form (SCDF) Jet Injector RxCUI 1672969 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 0.5 MG RxCUI 1011707
  4. Dose form (SCDF) Medicated Bar Soap RxCUI 1535616 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 0.005 MG/MG RxCUI 1535617
  5. Dose form (SCDF) Medicated Liquid Soap RxCUI 1999988 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 40 MG/ML RxCUI 2604567
  7. Dose form (SCDF) Medicated Patch RxCUI 1792943 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 0.04 MG/MG RxCUI 1012994 0.018 MG/MG RxCUI 2001434 0.035 MG/MG RxCUI 2199665 0.04 MG/MG RxCUI 1737778 0.0488 MG/MG RxCUI 2680724 0.05 MG/MG RxCUI 1745091
  8. Dose form (SCDF) Mucosal Spray RxCUI 393257 No current FDA listing
    Clinical drug / strength (SCD) hydrochloride 100 MG/ML RxCUI 1010053
  10. Dose form (SCDF) Ophthalmic Gel RxCUI 809468 No current FDA listing
    Clinical drug / strength (SCD) hydrochloride 0.035 MG/MG RxCUI 1009462
  11. Dose form (SCDF) Otic Solution RxCUI 1372898 No current FDA listing
    Clinical drug / strength (SCD) hydrochloride 40 MG/ML RxCUI 2595042
  15. Dose form (SCDF) Rectal Spray RxCUI 2624686 No current FDA listing
    Clinical drug / strength (SCD) hydrochloride 50 MG/ML RxCUI 2624687 50 MG/ML RxCUI 2637486
  16. Dose form (SCDF) Rectal Suppository RxCUI 2474634 No current FDA listing
    Clinical drug / strength (SCD) 50 MG RxCUI 2474635
  17. Dose form (SCDF) Topical Cream RxCUI 377740 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 20 MG/ML RxCUI 1432482 hydrochloride 30 MG/ML RxCUI 1010835 hydrochloride 32.5 MG/ML RxCUI 1593733 hydrochloride 37.5 MG/ML RxCUI 1600130 hydrochloride 38.8 MG/ML RxCUI 1723991 hydrochloride 40 MG/ML RxCUI 1010895 hydrochloride 41.2 MG/ML RxCUI 1947197 hydrochloride 50 MG/ML RxCUI 1491882 20 MG/ML RxCUI 106222 30 MG/ML RxCUI 2049533 39 MG/ML RxCUI 2108915 40 MG/ML RxCUI 1421893 50 MG/ML RxCUI 1534792
  18. Dose form (SCDF) Topical Gel RxCUI 377965 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 0.005 MG/MG RxCUI 1011849 hydrochloride 0.01 MG/MG RxCUI 1012204 hydrochloride 0.015 MG/MG RxCUI 2000538 hydrochloride 0.02 MG/MG RxCUI 1011852 hydrochloride 0.025 MG/MG RxCUI 1009433 hydrochloride 0.028 MG/MG RxCUI 2562183 hydrochloride 0.03 MG/MG RxCUI 1372891 hydrochloride 0.0388 MG/MG RxCUI 2675768 hydrochloride 0.04 MG/MG RxCUI 1010077 hydrochloride 0.05 MG/MG RxCUI 1010057 0.008 MG/MG RxCUI 1098616 0.04 MG/MG RxCUI 1291672
  20. Dose form (SCDF) Topical Ointment RxCUI 372598 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 0.025 MG/MG RxCUI 1009416 hydrochloride 0.04 MG/MG RxCUI 1858984 hydrochloride 0.05 MG/MG RxCUI 1010296 0.04 MG/MG RxCUI 2559400 0.05 MG/MG RxCUI 1543069
  21. Dose form (SCDF) Topical Solution RxCUI 372600 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 20 MG/ML RxCUI 1010774 hydrochloride 25 MG/ML RxCUI 1012955 hydrochloride 40 MG/ML RxCUI 1987647 hydrochloride 50 MG/ML RxCUI 2670601 30 MG/ML RxCUI 2607527 40 MG/ML RxCUI 2197844

Look up RxCUI 6387 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Lidocaine costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Patch · Topical 50 mg/g $2.00 each NDC details & price history
Ointment · Topical 50 mg/g $0.162 per gram NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Lidocaine brand names

Lidocaine is sold under 16 brand names in the FDA directory — Xylocaine, Akten, Lidoderm, Zingo and others. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Xylocaine Akten Lidoderm Zingo Solarcaine Regenecare Cutiecaine Burn Jel Plus Sonacaine Zcaine Dr. Numb Unburn AneCream Lmx Lidocream Recticare

Who makes Lidocaine: manufacturers and labelers

406 companies list Lidocaine products with the FDA. By number of product records, the largest are Veridian Healthcare, PureTek Corporation, HF Acquisition Co LLC, DBA HealthFirst. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

Veridian Healthcare 34 PureTek Corporation 27 HF Acquisition Co LLC, DBA HealthFirst 21 Medical Purchasing Solutions, LLC 20 Asclemed USA, Inc. 17 Bryant Ranch Prepack 16 Chattem, Inc. 16 Henry Schein, Inc. 16 CVS Pharmacy 14 Eugia US LLC 14 Fresenius Kabi USA, LLC 14 Hospira, Inc. 12 Lifestar Pharma LLC 12 Sambria Pharmaceuticals, LLC 12 YYBA Corp 12 Hikma Pharmaceuticals USA Inc. 11 Preferred Pharmaceuticals Inc. 11 Prodigy Media Inc 11 A-S Medication Solutions 10 Direct_Rx 10 Remedyrepack Inc. 10 Shanghai Chuangshi Medical Technology (Group) Co., Ltd. 10 Sportpharm LLC 10 Advanced Rx Pharmacy of Tennessee, LLC 9

…and 382 more on the FDA NDC directory.

Lidocaine drug class (RxNorm)

Lidocaine belongs to the Antiarrhythmic class.

Pharmacologic class Antiarrhythmic, Amide Local Anesthetic
Drug family (ATC) Antiarrhythmics, class Ib, Local anesthetics, Anesthetics for topical use

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Lidocaine page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

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FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Nov 1, 2024
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Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Lidocaine.
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Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
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Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Lidocaine after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
1,020
Finished products in the current FDA directory
1,142
Companies listing them (makers, repackagers, distributors)
406
FDA labeler codes behind them ⓘ
387
Linked representative label ⓘ
Scilex Pharmaceuticals Inc.
Linked label effective
Nov 1, 2024
Composite sections available
27
Linked SPL Set ID
a1b17507-4560-490d-a388-74e7fd7eaa5e
Linked SPL Document ID
25e03ec1-e3a9-2483-e063-6394a90ad2d8
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Scilex Pharmaceuticals Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →