FDA-filed SPL labeling · retrieved through openFDA

Ropivacaine

Ropivacaine is an amide local anesthetic injection used in adults to produce local or regional anesthesia for surgery and to manage acute pain.

Brand name Naropin
Drug classes ⓘ Amide Local Anesthetic
Rx Form 1 Routes Epidural, Infiltration, Perineural · Epidural; Infiltration; Perineural · Epidural · Epidural, Infiltration +3
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 29 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveMay 22, 2024
Clinical labels in scope ⓘ29
AvailabilityRx
Earliest approval/marketing year ⓘ1996
FDA-listed product records ⓘ190
Boxed warningNone found in compared labels
How we combine label and product data →
⭐ Ropivacaine at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Ropivacaine is a potent local anesthetic injection used by anesthesia professionals to numb specific areas of the body during surgery or to control acute pain such as labor or post-surgical pain. It is only given in clinical settings because of the risk of serious cardiovascular and nervous system effects if it enters the bloodstream. Always let your care team know about all other medications and any health conditions before receiving it.
How we write & review this content — our editorial policy →

📖 Ropivacaine: Patient Information Guide

A plain-language walkthrough of Ropivacaine — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

Ropivacaine hydrochloride injection is an amide local anesthetic used in adults for surgical anesthesia and acute pain management across multiple routes of administration.

  • Surgical anesthesia — epidural block: Numbs a region of the body for surgery, including cesarean section, via the epidural space
  • Surgical anesthesia — major nerve block: Blocks a large nerve or nerve cluster (perineural) to anesthetize a limb or region for surgery
  • Surgical anesthesia — local infiltration: Injected directly into tissue to numb a localized surgical area
  • Acute pain management — epidural infusion or bolus: Given as a continuous infusion or repeated doses through an epidural catheter to control postoperative pain or labor pain
  • Acute pain management — local infiltration: Injected into a specific area to relieve localized acute pain
  • Naropin (brand-name ropivacaine) is approved for the same full set of surgical anesthesia and acute pain management indications listed above
⚙️How it works▾

Ropivacaine belongs to the amino amide class of local anesthetics. It works by blocking the channels in nerve cell membranes that allow electrical signals to travel. By raising the threshold a nerve needs to fire, slowing how fast the impulse moves, and reducing the speed at which the electrical charge builds up, it temporarily prevents pain signals — and other sensory and motor signals — from reaching the brain. The numbness it produces follows a predictable order: pain goes first, then temperature sensitivity, then touch, then the sense of body position, and finally muscle control.

Unlike many other local anesthetics, adding epinephrine to ropivacaine does not meaningfully change how quickly it works or how long it lasts, and does not reduce how much is absorbed into the bloodstream.

💊How it's taken▾

Ropivacaine hydrochloride injection is administered only by trained anesthesia professionals — it is never taken by mouth or self-administered. Depending on the clinical situation, it may be injected into the epidural space, around a nerve or nerve bundle (perineural), or directly into a local area of tissue (infiltration). For ongoing pain management (such as after surgery or during labor), it may be delivered as a continuous epidural infusion or through periodic top-up doses via a catheter.

  • The dose, concentration, and method are always individualized by the anesthesia team based on the procedure, the area to be numbed, and your health status
  • Doses are always given slowly and in small increments to reduce the risk of side effects
  • There is no food restriction relevant to this injectable medication; follow all pre-procedure instructions from your surgical team
🤒Side effects — in detail▾

The most common side effects reported in clinical studies include:

  • Low blood pressure (hypotension) — the most frequently reported effect
  • Nausea and vomiting
  • Slow heart rate (bradycardia)
  • Headache and back pain
  • Itching (pruritus)
  • Tingling or altered sensation (paresthesia)
  • Fever, dizziness, and chills
  • Difficulty urinating (urinary retention)

Serious reactions — including seizures, cardiac arrhythmias, cardiac arrest, or a dangerous drop in blood pressure — can occur if too much drug enters the bloodstream. These require immediate emergency treatment and are why ropivacaine is only given in monitored clinical settings.

⚠️Warnings & precautions▾
  • Accidental intravenous injection is the most serious risk — if ropivacaine enters a blood vessel, it can cause life-threatening heart rhythm problems or cardiac arrest. This is why it is given slowly, in small increments, by trained clinicians only.
  • Central nervous system toxicity: Early warning signs include restlessness, ringing in the ears (tinnitus), metallic taste, blurred vision, numbness around the mouth, or tremors. These must be reported immediately — they can progress to seizures or loss of consciousness.
  • Methemoglobinemia (a dangerous condition where blood can no longer carry oxygen properly) has been reported. Watch for bluish skin or abnormal blood color, especially if you take other medications that carry this risk.
  • Chondrolysis (cartilage damage): Ropivacaine must NOT be infused directly into a joint after arthroscopic surgery. This unapproved use has caused permanent cartilage damage, most commonly in the shoulder.
  • Liver disease: Because ropivacaine is broken down by the liver, people with severe liver disease are at higher risk of toxic drug levels building up.
  • Older adults, very ill or debilitated patients: May need lower doses and extra monitoring due to greater sensitivity to the drug's effects.
🔀What it interacts with▾

Ropivacaine can interact with several types of medications, increasing the risk of side effects or toxicity:

  • Other local anesthetics or amide-type anesthetics: Toxic effects add together — the combination raises the risk of nervous system and heart side effects
  • Class III antiarrhythmic drugs (e.g., amiodarone): May have additive effects on heart rhythm; close monitoring, including ECG, is advised
  • CYP1A2 inhibitors (e.g., fluvoxamine): Can reduce the body's ability to clear ropivacaine by up to 70%, causing drug levels to rise significantly and increasing toxicity risk
  • CYP3A4 inhibitors (e.g., ketoconazole): May modestly slow how quickly ropivacaine is cleared from the body
  • Drugs associated with methemoglobinemia (e.g., nitroglycerin, benzocaine, dapsone, sulfonamides, chloroquine, acetaminophen in high exposure, metoclopramide): Combined use raises the risk of this dangerous blood oxygen disorder
  • Theophylline and imipramine: Possible interactions through competition for the same metabolic pathway (CYP1A2)

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it▾
  • Allergy to amide-type local anesthetics: Ropivacaine is contraindicated if you have a known allergy to ropivacaine or any other amide local anesthetic (e.g., lidocaine, bupivacaine)
  • Liver disease: Tell your doctor — ropivacaine is metabolized by the liver, and severe liver disease can lead to dangerously high drug levels
  • Kidney disease: The drug and its byproducts are cleared by the kidneys; impaired kidney function increases the risk of toxic buildup
  • Heart disease or heart rhythm problems: Use with caution — ropivacaine can affect cardiac conduction and is harder to tolerate with pre-existing heart conditions
  • Low blood pressure (hypotension) or low blood volume (hypovolemia): These conditions increase the risk of serious cardiovascular effects
  • Pregnancy: Ropivacaine crosses the placenta and can affect the fetus and newborn; the benefits and risks should be carefully discussed with your care team
  • Breastfeeding: Ropivacaine is present in breast milk at low levels; discuss with your doctor before use
  • Children: Safety and effectiveness in pediatric patients have not been established
  • Older adults: More sensitive to blood pressure drops and motor effects; lower starting doses and careful monitoring are recommended
  • Glucose-6-phosphate dehydrogenase (G6PD) deficiency or other conditions increasing methemoglobinemia risk: Inform your care team, as you may need closer monitoring
🚑If you take too much▾

Too much ropivacaine — whether from an excessive dose or accidental injection into a blood vessel — can cause serious nervous system effects (restlessness, tremors, seizures, loss of consciousness) and dangerous heart problems (arrhythmias, cardiac arrest). If any of these signs appear, the medication should be stopped immediately and emergency supportive care started, including oxygen, airway management, and treatment to control seizures or support circulation. Prolonged resuscitation may be needed in cardiac arrest cases.

📡Pharmacodynamics — effects in the body▾

At therapeutic doses, ropivacaine can cause changes in heart rate, conduction, and blood vessel tone as it is absorbed into the body's circulation. At toxic blood concentrations, it can depress the heart's electrical system, potentially causing heart block, dangerous arrhythmias, and cardiac arrest. Studies in human volunteers showed that ropivacaine caused less slowing of the heart's electrical conduction (less QRS widening) compared to bupivacaine at comparable doses. In older patients, epidural ropivacaine tends to produce a wider zone of numbness, a smaller drop in blood pressure during the first hour, and stronger muscle-blocking effects.

🔬Pharmacokinetics — how your body processes it▾

After epidural administration, ropivacaine is absorbed completely but in two phases — an initial rapid phase (roughly 14 minutes) followed by a slower phase (about 4 hours), which is the rate-limiting step in its elimination. It is highly protein-bound (about 94%), mainly to a blood protein called alpha-1-acid glycoprotein. Ropivacaine is extensively broken down by the liver, primarily through a pathway involving the enzyme CYP1A2, and about 86% of a dose is ultimately excreted in the urine as metabolites. The terminal half-life (how long it takes the body to clear half the drug) is roughly 1.8 hours after intravenous use and about 4.2 hours after epidural administration.

📦How to store it▾

Solutions should be stored at 20ºC to 25°C (68ºF to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F) .

📄 Written from Ropivacaine’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Ropivacaine — the kind of thing our pharmacy team would talk through with you at the counter.

What is ropivacaine actually used for? Why am I getting it? ▾
Ropivacaine is a local anesthetic — it temporarily blocks pain signals in a specific part of your body. You might be receiving it to keep you comfortable and pain-free during surgery (including a cesarean section), to block sensation in a limb or region before a procedure, or to manage pain after surgery or during labor through an epidural catheter. Your anesthesia team will explain exactly how it's being used in your case.
Will I be completely numb — can I move at all? ▾
It depends on the dose and concentration used. Ropivacaine blocks pain first, then temperature, then touch, and at higher concentrations it can reduce muscle movement too. For labor pain, your care team often uses a concentration that controls pain while allowing some movement. For surgery, more complete numbness — including muscle relaxation — is the goal. Your anesthesiologist tailors this to your situation.
What side effects should I expect after getting ropivacaine? ▾
The most common ones include a drop in blood pressure (which your care team monitors closely), nausea, vomiting, headache, back pain, and sometimes itching. These are generally manageable. The more serious — but rare — risks include heart rhythm changes or seizures if the drug somehow gets into a blood vessel, which is why it's always given slowly by trained professionals in a monitored setting. Tell your nurse or doctor right away if you notice ringing in your ears, a metallic taste, blurred vision, or feel your heart racing or pounding — those can be early warning signs that need immediate attention.
Is it safe to use during pregnancy or while breastfeeding? ▾
Ropivacaine is commonly used during labor and cesarean delivery, and your care team weighs the benefits and risks carefully. It does cross the placenta, so the fetus and newborn are monitored closely. It also appears in breast milk at low levels after use, but reports of harm to infants have not been documented. If you have concerns, have an honest conversation with your obstetrician and anesthesiologist — they can walk you through the specifics for your situation.
I take other medications — is there anything I need to watch out for? ▾
Yes, a few interactions matter. If you take fluvoxamine (an antidepressant), it can significantly slow your body's ability to clear ropivacaine, raising the level in your blood. Antiarrhythmic drugs like amiodarone can add to ropivacaine's effects on the heart. Other local anesthetics, if used at the same time, also have additive toxic effects. Make sure your anesthesia team has a complete list of everything you take — including over-the-counter medicines and supplements — before your procedure.
Are there any conditions that make ropivacaine riskier for me? ▾
Yes. If you have liver disease, your body may not break down ropivacaine as efficiently, which can cause levels to build up to a toxic range — especially with repeated doses. Kidney disease also increases the risk because the drug's byproducts are cleared by the kidneys. Heart disease, low blood pressure, or very low blood volume can make the cardiovascular side effects harder to tolerate. If you're older or in poor general health, you may need a lower dose. Always share your full medical history with your care team before any procedure.
Is Ropivacaine available over the counter? ▾
Ropivacaine is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.
When was Ropivacaine first available? ▾
Ropivacaine has been available in the United States since at least 1996, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Ropivacaine? ▾
Ropivacaine is supplied by 38 manufacturers listed in the FDA NDC Directory, including Fresenius Kabi USA, LLC, Baxter Healthcare Corporation, Hikma Pharmaceuticals USA Inc..

💬 Answers drafted from Ropivacaine’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

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💊 How Ropivacaine comes

Ropivacaine is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Injection

By injection · Infiltration · Into the epidural space · Perineural
Brands Naropin
How this form is used
What it may be used for
  • Naropin injection is approved for surgical anesthesia via epidural block (including cesarean section), major nerve block, and local infiltration
  • Naropin injection is approved for acute pain management via epidural continuous infusion or intermittent bolus (e.g., postoperative or labor pain) and local infiltration
  • Ropivacaine hydrochloride injection is approved for the same surgical anesthesia and acute pain management uses, delivered epidurally, perineurally, or by local infiltration
Important instructions
  • Ropivacaine hydrochloride injection and Naropin must be administered only by clinicians trained in regional anesthesia, with resuscitation equipment immediately on hand
  • Injections should always be given slowly and in incremental doses — never as a single rapid large-volume injection
  • Naropin and ropivacaine hydrochloride injection are not approved for intra-articular infusion (directly into a joint) due to the risk of cartilage damage
  • The smallest dose and concentration that achieves the desired anesthesia should always be used; your anesthesia team will determine the appropriate regimen for your procedure
Available strengths 6 strengths
2 mg/mL 5 mg/mL 7.5 mg/mL 10 mg/mL 150 mg/30 mL 1 kg/kg
176 FDA-listed product records ⓘ

📊 Ropivacaine across the U.S. market

How Ropivacaine appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

1
Dose forms ⓘ
38
Manufacturers
2
Brand names
190
FDA-listed product records ⓘ
1996
First marketed ⓘ

Also listed with the FDA, not a patient dose form: Powder (14) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Fresenius Kabi USA, LLC14%
Baxter Healthcare Corporation8%
Hikma Pharmaceuticals USA Inc.8%
Somerset Therapeutics, LLC7%
Caplin Steriles Limited7%
Eugia US LLC7%
Other makers47%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Ropivacaine is used

A general measure of how commonly Ropivacaine is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Ropivacaine is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

32,308
Medicaid prescriptions filled (Q1–Q4 2025)
$6M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Ropivacaine prescribed? Of the 1,596 medications we measure, Ropivacaine ranks #719 by Medicaid prescriptions — more than 55% of them.

Where Ropivacaine ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #719 of 1,596
#714 Gentamicin Injection 33,521 Rx #715 Benralizumab Injection 33,442 Rx #716 Ciclesonide Oral Inhal... 33,286 Rx #717 Indapamide 32,997 Rx #718 Dicloxacillin 32,884 Rx #719 Ropivacaine 32,308 Rx #720 Darunavir and Cobicist... 32,250 Rx #721 Cobicistat / Darunavir... 32,250 Rx #722 Certolizumab Injection 32,049 Rx #723 Penicillin G Benzathin... 31,924 Rx #724 Filgrastim Injection 31,849 Rx

Utilization by Ropivacaine product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 30 mL / 5 mg/mL injection is the most-dispensed Ropivacaine product — about 56% of these Medicaid prescriptions.

30 ML ropivacaine hydrochloride 5 MG/ML Injection Most dispensed

18,060 Medicaid prescriptions (Q1–Q4 2025) 56% of Ropivacaine prescriptions shown $3.7M gross reimbursement (before rebates) ≈ $207 per prescription (gross)

Summed across the 12 of 46 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734475

20 ML ropivacaine hydrochloride 5 MG/ML Injection

5,786 Medicaid prescriptions (Q1–Q4 2025) 18% of Ropivacaine prescriptions shown $2M gross reimbursement (before rebates) ≈ $342 per prescription (gross)

Summed across the 6 of 21 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734483

10 ML ropivacaine hydrochloride 2 MG/ML Injection

4,317 Medicaid prescriptions (Q1–Q4 2025) 13% of Ropivacaine prescriptions shown $77,411 gross reimbursement (before rebates) ≈ $18 per prescription (gross)

Summed across the 4 of 12 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734203

20 ML ropivacaine hydrochloride 2 MG/ML Injection

2,771 Medicaid prescriptions (Q1–Q4 2025) 9% of Ropivacaine prescriptions shown $198,778 gross reimbursement (before rebates) ≈ $72 per prescription (gross)

Summed across the 8 of 28 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734207

100 ML ropivacaine hydrochloride 2 MG/ML Injection

678 Medicaid prescriptions (Q1–Q4 2025) 2% of Ropivacaine prescriptions shown $2,771 gross reimbursement (before rebates) ≈ $4.09 per prescription (gross)

Summed across the 3 of 27 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734347

200 ML ropivacaine hydrochloride 2 MG/ML Injection

320 Medicaid prescriptions (Q1–Q4 2025) <1% of Ropivacaine prescriptions shown $215 gross reimbursement (before rebates) ≈ $0.67 per prescription (gross)

Summed across the 4 of 24 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734355

10 ML ropivacaine hydrochloride 10 MG/ML Injection

182 Medicaid prescriptions (Q1–Q4 2025) <1% of Ropivacaine prescriptions shown $10,812 gross reimbursement (before rebates) ≈ $59 per prescription (gross)

Summed across the 3 of 11 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734090

20 ML ropivacaine hydrochloride 10 MG/ML Injection

80 Medicaid prescriptions (Q1–Q4 2025) <1% of Ropivacaine prescriptions shown $13,164 gross reimbursement (before rebates) ≈ $165 per prescription (gross)

Summed across the 3 of 30 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734084

20 ML ropivacaine hydrochloride 7.5 MG/ML Injection

61 Medicaid prescriptions (Q1–Q4 2025) <1% of Ropivacaine prescriptions shown $7,629 gross reimbursement (before rebates) ≈ $125 per prescription (gross)

Summed across the 1 of 12 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 905189

200 ML ropivacaine hydrochloride 5 MG/ML Injection

42 Medicaid prescriptions (Q1–Q4 2025) <1% of Ropivacaine prescriptions shown $1,117 gross reimbursement (before rebates) ≈ $27 per prescription (gross)

Summed across the 2 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734481

100 ML ropivacaine hydrochloride 5 MG/ML Injection

11 Medicaid prescriptions (Q1–Q4 2025) <1% of Ropivacaine prescriptions shown

Summed across the 1 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1734479

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Ropivacaine, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 47 of 224 listed Ropivacaine NDCs with Medicaid activity.

🔍 Compare Ropivacaine products

A representative set of FDA-listed product records for Ropivacaine — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 190 of 190 products — FDA National Drug Code Directory. See every product, package size and price: browse all 190 Ropivacaine NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Ropivacaine RxCUI 35780 2 dose forms · 13 strengths
  1. Dose form (SCDF) Injection RxCUI 1734083 In current FDA listings
    Clinical drug / strength (SCD) 10 ML ropivacaine hydrochloride 10 MG/ML RxCUI 1734090 10 ML ropivacaine hydrochloride 2 MG/ML RxCUI 1734203 20 ML ropivacaine hydrochloride 10 MG/ML RxCUI 1734084 20 ML ropivacaine hydrochloride 2 MG/ML RxCUI 1734207 20 ML ropivacaine hydrochloride 5 MG/ML RxCUI 1734483 20 ML ropivacaine hydrochloride 7.5 MG/ML RxCUI 905189 30 ML ropivacaine hydrochloride 5 MG/ML RxCUI 1734475 100 ML ropivacaine hydrochloride 2 MG/ML RxCUI 1734347 100 ML ropivacaine hydrochloride 5 MG/ML RxCUI 1734479 200 ML ropivacaine hydrochloride 2 MG/ML RxCUI 1734355 200 ML ropivacaine hydrochloride 5 MG/ML RxCUI 1734481
  2. Dose form (SCDF) Prefilled Syringe RxCUI 1996290 No current FDA listing
    Clinical drug / strength (SCD) 10 ML ropivacaine hydrochloride 2 MG/ML RxCUI 1996297 10 ML ropivacaine hydrochloride 5 MG/ML RxCUI 1996291

Look up RxCUI 35780 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Naropin

🏭 Manufacturers & labelers

Fresenius Kabi USA, LLC 27 Baxter Healthcare Corporation 16 Hikma Pharmaceuticals USA Inc. 15 Somerset Therapeutics, LLC 14 Caplin Steriles Limited 14 Eugia US LLC 14 Sagent Pharmaceuticals 9 Amneal Pharmaceuticals LLC 8 Hospira, Inc. 8 AuroMedics Pharma LLC 7 Meitheal Pharmaceuticals Inc. 7 Glenmark Pharmaceuticals Inc., USA 5 NorthStar Rx LLC 4 Excella GmbH & Co. KG 4 Henry Schein, Inc. 4 Civica, Inc. 3 Anthea Pharma Private Limited 3 Mylan Institutional LLC 2 SOLA Pharmaceuticals, LLC 2 Akorn 2 Sportpharm LLC 2 Gland Pharma Limited 2 General Injectables & Vaccines, Inc 2 Apothecon Pharmaceuticals Pvt Ltd 2

…and 14 more on the FDA NDC directory.

RxNorm drug class

Ropivacaine belongs to the Amide Local Anesthetic class.

Pharmacologic class Amide Local Anesthetic
Drug family (ATC) Amides

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective May 22, 2024
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Ropivacaine.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Ropivacaine after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
29
NDC products indexed
190
Distinct labelers/manufacturers represented
38
Linked representative label ⓘ
Fresenius Kabi USA, LLC
Linked label effective
May 22, 2024
Composite sections available
23
Linked SPL Set ID
56dfabf7-f7a8-4601-b17a-cb16fb995b0f
Linked SPL Document ID
75465ceb-e894-487d-aa80-671fa0841fce
Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 29 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Fresenius Kabi USA, LLC is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.