Home › NDC Lookup › Ingredients › Avobenzone And Octisalate › 11559-0049-02
DAYWEAR MULTI-PROTECTION ANTII-OXIDANT 24H-MOISTURE CREME BROAD SPECTRUM SPF 15 NORMAL/COMBINATION SKIN AVOBENZONE and OCTISALATE 30 mg/mL; 50 mg/mL Cream — NDC 11559-0049-02 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

DAYWEAR MULTI-PROTECTION ANTII-OXIDANT 24H-MOISTURE CREME BROAD SPECTRUM SPF 15 NORMAL/COMBINATION SKIN AVOBENZONE and OCTISALATE 30 mg/mL; 50 mg/mL Cream — NDC 11559-049-02 (Billing 11559-0049-02)

by ESTEE LAUDER INC · 1 JAR in 1 CARTON / 15 mL in 1 JAR

This is a package of DAYWEAR MULTI-PROTECTION ANTII-OXIDANT 24H-MOISTURE CREME BROAD SPECTRUM SPF 15 NORMAL/COMBINATION SKIN AVOBENZONE and OCTISALATE 30 mg/mL; 50 mg/mL Cream from ESTEE LAUDER INC, no longer marketed (first marketed Dec 2017), no longer in the FDA NDC Directory.

NDC 11559-0049-02
🏷️ FDA NDC (as labeled) 11559-049-02 billing pads the product segment with a zero
This package
Contains15 mL in 1 jar Pack sizes4 compare ↓
Product page 11559-0049-01 Also comes in: 50 mL 11559-049-01 7 ml 11559-049-04 30 ml 11559-049-03
OTC Discontinued Non-controlled ⚠ Inactivated by FDA ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 11559-049-02 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
11559 labeler · 049 product · 02 package
Package marketed since
Dec 1, 2022
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 1155904902 1
FDA record last changed
Jul 24, 2026
⚠️
Excluded from the active FDA NDC Directory. FDA inactivated this product’s listing record, so it is excluded from the active NDC Directory. The listing was last certified through Dec 2026. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 11559-049-02
Product NDC 11559-049
11-digit billing NDC 11559004902
UNII G63QQF2NOX, 4X49Y0596W
Application # M020
SPL Set ID 46fa88a3-b187-41da-9373-005182ec1083
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status Discontinued
FDA listing status Inactivated by FDA (certified through Dec 2026)
Marketing start 2017-12-01
Route TOPICAL
Dosage form CREAM
Substance AVOBENZONE; OCTISALATE
Why two NDCs? The FDA registers this code as 11559-049-02 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 11559-0049-02. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

This is an over-the-counter monograph sunscreen cream for topical application to the face, formulated for normal to combination skin. It contains two UV filter ingredients, avobenzone and octisalate, which are commonly used together in sunscreens to help protect skin from ultraviolet rays and are labeled with a broad spectrum SPF 15 rating. The product is also marketed as a moisturizer with antioxidant ingredients intended for daytime facial care. As an OTC monograph product, it is manufactured according to FDA category rules rather than as an individually approved application.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 50 mL 7 ml 30 ml
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
11559-0049-01 11559-049-01 Main listing 1 JAR in 1 CARTON / 50 mL in 1 JAR 2017-12-01 — Inactivated by FDA
11559-0049-02 You're viewing this 1 JAR in 1 CARTON / 15 mL in 1 JAR 2022-12-01 — Inactivated by FDA
11559-0049-03 11559-049-03 30 mL in 1 JAR 2022-12-01 — Inactivated by FDA
11559-0049-04 11559-049-04 7 mL in 1 JAR 2022-12-01 — Inactivated by FDA

Pack size FAQ

What quantity is in this package?
This package is listed by the FDA — 1 jar in 1 carton / 15 ml in 1 jar.
What NDC number is used to bill for this package of DAYWEAR MULTI-PROTECTION ANTII-OXIDANT 24H-MOISTURE CREME BROAD SPECTRUM SPF 15 NORMAL/COMBINATION SKIN AVOBENZONE and OCTISALATE 30 mg/mL; 50 mg/mL Cream?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Clinique Smart Custom Repair Moisturizer Broad Spectrum Spf 15 - Very Dry/Dry 30 mg/mL; 50 mg/mL 49527-0048-01 CLINIQUE 1 jar — — FDA listed —
Clinique Smart Custom Repair Moisturizer Broad Spectrum Spf 15 - Combination/Oily To Oily 30 mg/mL; 50 mg/mL 49527-0050-01 CLINIQUE 1 jar — — FDA listed —
CLINIQUE FOR MEN SUPER ENGERGIZER ANTI -FATIGUE HYDRATING Concentrate BROAD SPECTRUM SPF 25 30 mg/mL; 50 mg/mL 49527-0063-01 CLINIQUE 1 bottle — — FDA listed —
Clinique Smart Broad Spectrum Spf 15 Custom-Repair Moisturizer Dry Combination 30 mg/mL; 50 mg/mL 49527-0051-01 CLINIQUE 1 jar — — Discontinued —
Daywear Multi-Protection Antii-Oxidant 24H-Moisture Creme Broad Spectrum Spf 15 Normal/Combination Skin 30 mg/mL; 50 mg/mLthis 11559-0049-02 ESTEE 1 jar — — Discontinued —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2017
On the market since
Dec 2017
📍
2026
Currently FDA-listed
9 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerESTEE LAUDER INC
FDA applicationM020 (OTC MONOGRAPH DRUG)
Labeler code11559
First marketedDec 2017
Product typeHuman Otc Drug
Portfolio23 products on file

More NDCs from ESTEE LAUDER INC labeler code 11559

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 30 words ▾

Uses helps prevent sunburn if used as directed with other sun protection measures (see Directions ) decreases the risk of skin cancer and early skin aging caused by the sun

⏱️ Dosage and Administration 98 words ▾

Directions For sunscreen use: apply liberally and evenly 15 minutes before sun exposure reapply at least every two hours use a water resistant sunscreen if swimming or sweating Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m. – 2 p.m. wear long-sleeved shirts, pants, hats and sunglasses children under 6 months of age: ask a doctor

⚠️ Warnings 56 words ▾

Warnings For external use only Do not use on damaged or broken skin When using this product keep out of eyes. Rinse with water to remove. Stop use and ask a doctor if rash occurs Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 14 words ▾

Other information protect the product in this container from excessive heat and direct sun

🧪 Active Ingredient 9 words ▾

Active ingredients Purpose Avobenzone 3.00% Sunscreen Octisalate 5.00% Sunscreen

🧪 Inactive Ingredients ~1 min read ▾

Inactive ingredients water\aqua\eau • dimethicone • butyloctyl salicylate • butylene glycol • polyester-8 • cetyl ricinoleate • steareth-21 • steareth-2 • di-c12-15 alkyl fumarate • caprylic/capric/myristic/stearic triglyceride • polysilicone-11 • psidium guajava (guava) fruit extract • gentiana lutea (gentian) root extract • polygonum cuspidatum root extract • stearyl alcohol • hordeum vulgare (barley) extract\extrait d'orge • laminaria ochroleuca extract • rosmarinus officinalis (rosemary) leaf extract • triticum vulgare (wheat) germ extract • artemia extract • caffeine • pentylene glycol • hydrolyzed rice extract • vitis vinifera (grape) seed extract • hydrolyzed rice bran extract • lauryl peg-9 polydimethylsiloxyethyl dimethicone • thermus thermophillus ferment • behenyl alcohol • acrylic acid/vp crosspolymer • triacontanyl pvp • glycerin • c12-15 alkyl benzoate • linoleic acid • cholesterol • squalane • sodium pca • 1,2-hexanediol • urea • caprylic/capric triglyceride • dipropylene glycol dibenzoate • tocopheryl acetate • acrylamide/sodium acryloyldimethyltaurate copolymer • tetrahexyldecyl ascorbate • sodium hyaluronate • ergothioneine • isohexadecane • ppg-15 stearyl ether benzoate • glycyrrhetinic acid • trehalose • polyquaternium-51 • polysorbate 80 • potassium sorbate • lecithin • hydrogenated lecithin • glucose • palmitoyl hydroxypropyltrimonium amylopectin/glycerin crosspolymer • caprylyl glycol • cyclodextrin • sodium hydroxide • nordihydroguaiaretic acid • sodium chloride • triacetin • ascorbyl tocopheryl maleate • fragrance (parfum) • citric acid • ethylbisiminomethylguaiacol manganese chloride • pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate • disodium edta • bht • chlorphenesin • sodium dehydroacetate • phenoxyethanol • blue 1 (ci 42090) • yellow 5 (ci 19140) • chromium hydroxide green (ci 77289) <iln48627>

🎯 Purpose 9 words ▾

Active ingredients Purpose Avobenzone 3.00% Sunscreen Octisalate 5.00% Sunscreen

📄 Do Not Use 8 words ▾

Do not use on damaged or broken skin

📄 When Using This Product 13 words ▾

When using this product keep out of eyes. Rinse with water to remove.

📄 Stop Use and Ask a Doctor If 9 words ▾

Stop use and ask a doctor if rash occurs

📄 Keep Out of Reach of Children 21 words ▾

Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away.

📄 Package Label / Principal Display Panel 33 words ▾

PRINCIPAL DISPLAY PANEL - 50 ml Jar Carton ESTĒE LAUDER DayWear Multi-Protection Anti-Oxidant 24H-Moisture Creme Broad Spectrum SPF 15 NORMAL/COMBINATION SKIN POIDS NET WT.

1.7OZ. / 50 ml e Principal Display Panel

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Does this product come in other package sizes?
Yes — the FDA directory lists 3 other package presentations of this same product, including 1 jar (11559-0049-01), 7 ml (11559-0049-04), 30 ml (11559-0049-03). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
ESTEE LAUDER INC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 11559-0030-01 · ESTEE 11559-0050-01 · ESTEE →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.