Antiseptic Skin Cleanser Chlorhexidine Gluconate 4% 4 mg/100mL Liquid, 237 mL
by AmerisourceBergen Drug Corporation · 237 mL in 1 BOTTLE, PLASTIC (46122-137-34)
NDC 46122-0137-34
🏷️ FDA NDC (as labeled)
46122-137-34
billing pads the product segment with a zero
This package
Also priced by: Medicaid pays $0.0504/unit — full pricing hub ↓
Also comes in:
473 ml 46122-0137-43
OTC
Brand
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
46122-137-34
Product NDC
46122-137
11-digit billing NDC
46122013734
NCPDP billing unit
ML — per mL (volume)
RxCUI
211365
UNII
MOR84MUD8E
UPC
0346122137348, 0346122137430
Application #
NDA019125
SPL Set ID
12ace9af-14ed-2dea-e054-00144ff8d46c
Physiologic effect
Decreased Cell Wall Integrity
DEA schedule
Non-controlled
Marketing category
NDA
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2013-04-01
Marketing end
2027-02-28
Route
TOPICAL
Dosage form
LIQUID
Substance
CHLORHEXIDINE GLUCONATE
GPI-14
92100030102020
GPI class
GNP Antiseptic Skin Cleanser
GCN Seq No
007254
GCN
30011
HICL code
004297
Ingredient (HICL)
Chlorhexidine Gluconate
HIC1 code
Q
Therapeutic class — broad (HIC1)
Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code
Q5
Therapeutic class — intermediate (HIC2)
Agents Acting Principally On The Skin
HIC3 code
Q5B
Therapeutic class — specific (HIC3)
Topical Preparations,Antibacterials
AHFS code
08:30.04.00
AHFS class
Amebicides
FDB label name
ANTISEPTIC SKIN CLEANSER 4%
FDB brand name
Antiseptic Skin Cleanser
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 46122-137-34 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 46122-0137-34. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Antiinfectives and antiseptics for local oral treatment class.
Drug family (ATC)
Antiinfectives and antiseptics for local oral treatment, Antiinfectives, Biguanides and amidines
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerAmerisourceBergen Drug Corporation
Application holderXTTRIUM LABORATORIES INC
FDA applicationNDA019125 (NDA)
Labeler code46122
First marketedApr 2013
Product typeHuman Otc Drug
Portfolio37 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name ANTISEPTIC SKIN CLEANSER 4% Ingredient Chlorhexidine Gluconate
📗 Our plain-language guide HelloPharmacist
- It's actually a prescription-strength antimicrobial rinse, which is different from over-the-counter mouthwash. Your dentist prescribes it specifically to treat gingivitis — that's...
- What exactly is chlorhexidine rinse for — is it just like a regular mouthwash?
- Yes, tooth and surface staining is one of the most common side effects of chlorhexidine oral rinse. It can also increase tartar buildup on your teeth. The good news is that this is...
- My teeth look like they're staining — is that from the rinse?
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Chlorhexidine Gluconate 4%?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.037 | $8.67 / 237 ml |
| Medicaid paysCMS SDUD · 12 mo | $0.0504 | $11.94 / 237 ml |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per mL) — tap or hover for the price & month
▲ Up 102% over the last 24 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Antiseptic Skin Cleanser 4 g/100mL 70000-0407-01 | Cardinal | 237 ml | $0.025 | — | FDA listed | save 31% |
| Antiseptic Skin Cleanser 4 g/100mL 00116-1061-04 | Xttrium | 118 ml | $0.034 | — | Availability likely | save 8% |
| Antiseptic Skin Cleanser 4 mg/100mLthis 46122-0137-34 | AmerisourceBergen | 237 ml | $0.037 | — | Availability likely | — |
| Foster and Thrive 4 g/100mL 70677-1221-01 | McKesson | 237 ml | $0.037 | — | Availability likely | — |
| Chlorhexidine Gluconate 40 mg/mL 16571-0111-12 | Rising | 118 ml | $0.040 | — | Availability likely | +9% |
| Betasept .04 mg/mL 67618-0200-04 | Atlantis | 118 ml | $0.040 | — | Availability likely | +9% |
| Cardinal Health 4 g/100mL 00116-0061-04 | Xttrium | 118 ml | — | — | Discontinued | — |
| Antiseptic Skin Cleanser 4 mg/100mL 00116-0137-34 | Xttrium | 237 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 mg/100mL 00116-0161-08 | Xttrium | 237 ml | — | — | FDA listed | — |
| Betasept .04 mg/mL 00116-0200-01 | Xttrium | 3785 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 mg/100mL 00116-0401-50 | Xttrium | 237 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 g/100mL 00116-0407-01 | Xttrium | 237 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 g/100mL 00116-0767-08 | Xttrium | 237 ml | — | — | FDA listed | — |
| CliniClean 4 g/100mL 00116-0901-05 | Xttrium | 118 ml | — | — | Discontinued | — |
| Dyna-Hex 4 4 g/100mL 00116-1060-18 | Xttrium | 535 ml | — | — | FDA listed | — |
| Foster and Thrive 4 g/100mL 00116-1221-01 | Xttrium | 237 ml | — | — | FDA listed | — |
| Bactoshield CHG 40 mg/mL 00116-1344-08 | Xttrium | 3780 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 mg/100mL 00116-3678-07 | Xttrium | 473 ml | — | — | FDA listed | — |
| Hibiclens 4 g/100mL 00234-0575-40 | Molnlycke | 118 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 mg/100mL 00363-1061-08 | Walgreen | 237 ml | — | — | FDA listed | — |
| Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% 40 mg/mL 00404-0219-01 | Henry | 118 ml | — | — | FDA listed | — |
| Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% 40 mg/mL 00404-0220-03 | Henry | 236 ml | — | — | FDA listed | — |
| Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% 40 mg/mL 00404-0221-04 | Henry | 473 ml | — | — | FDA listed | — |
| Bactoshield CHG 40 mg/mL 11084-0039-03 | SC | 118 ml | — | — | FDA listed | — |
| Bactoshield CHG 40 mg/mL 11084-0128-03 | SC | 118 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 g/100mL 11822-0116-05 | Rite | 237 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 g/100mL 11822-0891-02 | Rite | 532 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 mg/100mL 11822-3678-07 | Rite | 473 ml | — | — | FDA listed | — |
| BD E-Z Scrub 107 40 g/1000mL 17271-0107-03 | Becton | 18 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 mg/100mL 36800-0401-50 | Topco | 237 ml | — | — | FDA listed | — |
| Halyard Chlorhexidine Gluconate 40 mg/mL 39892-0960-01 | Owens | 118 ml | — | — | FDA listed | — |
| Halyard Chlorhexidine Gluconate 40 mg/mL 39892-0961-01 | Owens | 118 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 mg/100mL 41250-0162-08 | Meijer | 237 ml | — | — | Discontinued | — |
| Scrub, Scrub-Stat, Foam Safe, Micro-Guard 40 mg/mL 42939-0125-19 | AVA, | 946 ml | — | — | FDA listed | — |
| Scrub, Scrub-Stat, Foam Safe, Micro-Guard 40 mg/mL 42939-0128-01 | AVA, | 118 ml | — | — | FDA listed | — |
| Scrub-Stat 40 mg/mL 47593-0464-11 | Ecolab | 3780 ml | — | — | FDA listed | — |
| Scrub-Stat 40 mg/mL 47593-0468-21 | Ecolab | 208000 ml | — | — | Discontinued | — |
| Antiseptic Skin Cleanser 4 g/100mL 59779-0767-08 | CVS | 237 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 mg/100mL 63868-0940-08 | Chain | 237 ml | — | — | FDA listed | — |
| Antiseptic Skin Cleanser 4 g/100mL 68599-5401-00 | McKesson | 4 bottles | — | — | FDA listed | — |
| CliniClean 4 g/100mL 69464-0901-05 | HR | 118 ml | — | — | Discontinued | — |
| Hibiclens 4 g/100mL 76420-0535-08 | Asclemed | 236 ml | — | — | FDA listed | — |
| Surgical Scrub Brush/Sponge With Nail Cleaner 4% CHG 4 g/100mL 84128-0003-01 | Xinxiang | 30 patches | — | — | FDA listed | — |
About this product: this is the brand-name version. Some generic versions are approved by the FDA, but we could not confirm current pharmacy availability from our pricing/market data.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2013
On the market since
Apr 2013
📍
2026
Currently FDA-listed
13 years listed
🔒
·
Generic approved (availability unconfirmed)
see note
🔒Generic approved by FDA, but pharmacy availability is not confirmed
The FDA lists approved generic versions of this medicine, but that does not always mean a pharmacy can get one today. Patent rules, launch agreements, supply and pricing can affect when generics actually arrive.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🗺️ Medicaid utilization & spend
📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 46122-0137-34, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q4 2025 · 4 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
180
Units reimbursed last 4 qtrs
44.1K
Gross reimbursed last 4 qtrs
$2.2K
Avg / prescription
$12.34
Avg / unit
$0.0504
Latest quarter Q4 2025
33Rx
Medicaid pays / mL
$0.0504
gross reimbursed
vs
NADAC / mL
$0.0366
acquisition cost
=
Spread
+$0.0138
+38% vs cost
What Medicaid paid per mL (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
Fee-for-service · 0 Rx Managed care · 180 Rx
State Medicaid map
Units reimbursed · per 100k residents
52.3539
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
Prescriptions—
Units—
Reimbursed—
🏆 Top states by units · per 100k residents
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.
💊 Medicaid utilization by pack size
Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
Drug total (last 4 qtrs): 233 Rx · 66,571 units · $3,223 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Antiseptic Skin Cleanser (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 25%
Female · 75%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Per unit | Per pack | Marketing start | Status |
|---|---|---|---|---|---|
| 46122-0137-34 You're viewing this | 237 mL in 1 BOTTLE, PLASTIC (46122-137-34) | $0.0366 / mL | $8.68 | 2013-04-01 | Active |
| 46122-0137-43 | 473 mL in 1 BOTTLE (46122-137-43) | $0.0178 / mL | $8.40 | 2019-01-01 | Active |
You're viewing the smallest of 2 pack sizes for this product.
Per mL, this pack runs about 106% above the cheapest pack (473 mL, $0.0178 vs $0.0366 NADAC).
In Medicaid, this is the most-dispensed pack of this product — about 77% of fills over the last four reported quarters. See all packs ↓
Pack size FAQ
What quantity is in NDC 46122-0137-34?
NDC 46122-0137-34 contains 237 mL — 237 ml in 1 bottle, plastic.
What is the difference between NDC 46122-0137-34 and NDC 46122-0137-43?
Both are Antiseptic Skin Cleanser Chlorhexidine Gluconate 4% 4 mg/100mL Liquid — the drug itself is identical. NDC 46122-0137-34 is the 237 mL package, while NDC 46122-0137-43 is the 473 ml package. Per-mL NADAC also differs: $0.0366 here vs $0.0178 for the 473 ml pack.
What NDC number is used to bill for this package of Antiseptic Skin Cleanser Chlorhexidine Gluconate 4% 4 mg/100mL Liquid?
Bill NDC 46122-0137-34 — the 11-digit billing format is 46122013734. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.
Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses healthcare personnel handwash : helps reduce bacteria that potentially can cause disease skin wound and general skin cleansing
⏱️ Dosage and Administration ▾
Directions use with care in premature infants or infants under 2 months of age. These products may cause irritation or chemical burns. Healthcare personnel handwash: wet hands with water dispense about 5ml of product into cupped hands and wash in vigorous manner for about 15 seconds rinse and dry thoroughly Skin wound and normal skin cleansing: thoroughly rinse the area to be cleaned with water apply the minimum amount of product necessary to cover the skin or wound area and wash gently rinse again thoroughly
⚠️ Warnings ▾
Warnings For external use only Allergy alert: This product may cuase a severe allergic reaction. Symptoms may include: wheezing/difficulty breathing shock facial swelling hives rash If an allergic reaction occurs, stop use and seek medical help right away. Do not use if you or the patient is allergic to chlorhexidine gluconate or any other ingredient in this product in contact with meninges in the genital area Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away.
Stop use and ask doctor if irritation, sensitization, or allergic reaction occurs. These may be signs of a serious condition. When using this product keep out of eyes, ears, and mouth.
May cause serious and permanent eye injury if permitted to enter and remain in the eye or may cuase deafness when instilled in the middle ear through perforated eardrums. if solution should contact these areas, rinse out promptly and thoroughly with water wounds which involve more than the superficial layers of the skin should not be routinely treated repeated general skin cleansing of large body areas should not be done except when advised by a healthcare provider
📦 Storage and Handling ▾
Other information store at 20°-25° C (68°-77° F) avoid excessive heat above 40° C (104° F)
🧪 Active Ingredient ▾
Active Ingredients Chlorhexidine Gluconate 4% Solution
🧪 Inactive Ingredients ▾
Inactive ingredients cocamide DEA, fragrance, glucono-delta-lactone, hydroxyethylcellulose, isopropyl alcohol, lauramine oxide, PEG-75 lanolin, purified water, tridecyl alcohol.
🎯 Purpose ▾
Purpose Antiseptic
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.