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CVS Health Sunburn Relief Cooling Lidocaine 0.5 Pain-Relieving Lidocaine HCl 5 mg/g Gel, 170 g — NDC 51316-0022-15 package photo

CVS Health Sunburn Relief Cooling Lidocaine 0.5 Pain-Relieving Lidocaine HCl 5 mg/g Gel, 170 g

by CVS Pharmacy · 170 g in 1 BOTTLE (51316-022-15)
NDC 51316-0022-15
🏷️ FDA NDC (as labeled) 51316-022-15 billing pads the product segment with a zero
This package
Contains170 g Pack sizes2 compare ↓
Also comes in: 567 g 51316-0022-20
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 51316-022-15
Product NDC 51316-022
11-digit billing NDC 51316002215
RxCUI 1011849
UNII V13007Z41A
UPC 0050428384992
Application # M017
SPL Set ID f0f1969d-10e0-76ee-e053-2995a90a7336
Established class (EPC) Amide Local Anesthetic; Antiarrhythmic
Physiologic effect Local Anesthesia
Chemical class Amides
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2018-10-05
Route TOPICAL
Dosage form GEL
Substance LIDOCAINE HYDROCHLORIDE
Why two NDCs? The FDA registers this code as 51316-022-15 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 51316-0022-15. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Antiarrhythmic class.

Pharmacologic class Antiarrhythmic, Amide Local Anesthetic
Drug family (ATC) Antiarrhythmics, class Ib, Local anesthetics, Anesthetics for topical use
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerCVS Pharmacy
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code51316
First marketedOct 2018
Product typeHuman Otc Drug
Portfolio550 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📗 Our plain-language guide HelloPharmacist
  • It's best to avoid using two lidocaine products at the same time unless your doctor says it's okay. When you use multiple products containing a local anesthetic, the total amount a...
  • Can I use a lidocaine patch and a lidocaine cream at the same time?
  • No — please don't do this. Heat significantly increases how much lidocaine is absorbed through your skin, which can push drug levels in your blood higher than they should be. Stick...
  • Can I put a heating pad on the area where I applied a lidocaine patch?
📖 Read our full Lidocaine guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII ZY81Z83H0X
    Aloe vera leaf is a plant extract derived from the aloe plant. It is used in medicines as a natural moisturizer and skin-soothing agent in topical formulations.
  • UNII LKG8494WBH
    Benzyl alcohol is a clear liquid used as a preservative and solvent in medicines. It helps prevent bacterial and fungal growth and dissolves other ingredients to create uniform liquid formulations.
  • UNII 59TL3WG5CO
    A synthetic polymer made by crosslinking acrylic acid with allyl sucrose. It thickens liquids, forms gels, and helps control how fast the medicine is released in your body.
  • UNII MP1J8420LU
    A salt derived from edetic acid that binds to trace metals in medicines. It serves as a chelating agent and preservative to prevent metal-catalyzed breakdown of the drug and extend shelf life.
  • UNII H3R47K3TBD
    FD&C Blue No. 1 is a synthetic blue dye approved for use in foods and medicines. It serves as a colorant to give the medication its distinctive appearance and help with product identification.
  • UNII O020065R7Z
    A synthetic emulsifier derived from isocetyl alcohol and ethylene oxide. It helps mix oil and water-based ingredients together and improves the texture and stability of creams, lotions, and ointments.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII 1W6L629B4K
    Sulisobenzone is a chemical UV filter used in some topical products to help protect against sun damage. It works as a sunscreen ingredient that absorbs ultraviolet light before it reaches the skin.
  • UNII 9O3K93S3TK
    Trolamine is an alkaline compound used as a pH buffer and emulsifier in medicines. It helps neutralize acids, stabilize formulations, and enable mixing of oil and water-based ingredients.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

10 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesAloe Barbadensis Leaf Juice, Benzophenone-4, Benzyl Alcohol, Blue 1, Carbomer, Isoceteth-20, Phenoxyethanol, Tetrasodium EDTA, Triethanolamine.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 567 g
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Walgreens Cooling 5 mg/g 00363-0954-80 WALGREEN 226 g — — FDA listed —
Sunburn Relief 5 mg/g 11822-0776-03 Rite 226 g — — FDA listed —
Sunburn Relief Gel 5 mg/g 30400-0605-01 Jell 170 g — — FDA listed —
TopCare Everyday After Sun Cooling 5 mg/g 36800-0953-80 TOPCO 226 g — — FDA listed —
0.5% Lidocaine Burn Relief .5 g/100g 43473-0099-08 Nantong 3 bottles — — FDA listed —
Good Sense Burn Relief Aloe .5 g/100g 50804-0955-08 Geiss, 227 g — — FDA listed —
CVS Health Sunburn Relief Cooling Lidocaine 0.5 Pain-Relieving 5 mg/gthis 51316-0022-15 CVS 170 g — — FDA listed —
0.5% Lidocaine Burn Relief .5 g/100g 52000-0437-08 Universal 3 bottles — — FDA listed —
MyDerm Aloe and Lidocaine .5 g/100mL 53329-0037-09 Medline 592 ml — — FDA listed —
Sunburn Relief 5 mg/g 55910-0177-34 Old 226 g — — FDA listed —
burnrelief 5 mg/g 56062-0942-34 Publix 226 g — — FDA listed —
QC Burn Relief Aloe .5 g/100g 63868-0095-08 Chain 227 g — — FDA listed —
Aloe Vera Gel 5 mg/g 63941-0005-34 Valu 226 g — — FDA listed —
Sunburn Relief Gel 5 mg/g 69842-0909-34 CVS 226 g — — FDA listed —
HealthWise Soothing Lidocaine Pain Relief .5 g/g 71101-0986-01 Veridian 1 bottle — — FDA listed —
Sunburn Relief Gel 5 mg/g 72288-0005-34 Amazon.com 226 g — — FDA listed —
MyDerm .5 g/100mL 72667-0008-01 Inspec 237 ml — — FDA listed —
MyDerm Aloe and Lidocaine .5 g/100mL 72667-0283-09 Inspec 592 ml — — FDA listed —
DCH Burn Relief .5 g/100g 72839-0955-08 Derma 227 g — — FDA listed —
equate Burn Relief .5 g/100g 79903-0237-08 Walmart 226 g — — FDA listed —
Caring mill Lidocaine Aloe Gel Burn and Pain Relief 5 mg/mL 81522-0953-01 FSA 237 ml — — FDA listed —
Serum X .5 g/100g 82317-0001-01 AO 1 packet — — FDA listed —
Pain Relieving Gel 5 mg/g 83324-0183-08 Chain 226 g — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2018
On the market since
Oct 2018
📍
2026
Currently FDA-listed
8 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📊 Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Lidocaine HCl Viscous (matched by generic name) — the program that covers self-administered drugs. 4 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Lidocaine HCl Viscous. CMS lists 5 products for this generic; we show the highest-spend one. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$2.02M
Claims incl. refills
110.4K
Beneficiaries
87.1K
Spend / beneficiary
$23.19
Spend / claim
$18.30
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
51316-0022-15 You're viewing this 170 g in 1 BOTTLE (51316-022-15) 2018-10-05 Active
51316-0022-20 567 g in 1 BOTTLE (51316-022-20) 2018-10-05 Active

You're viewing the smallest of 2 pack sizes for this product.

Pack size FAQ

What quantity is in NDC 51316-0022-15?
NDC 51316-0022-15 contains 170 g — 170 g in 1 bottle.
What is the difference between NDC 51316-0022-15 and NDC 51316-0022-20?
Both are CVS Health Sunburn Relief Cooling Lidocaine 0.5 Pain-Relieving Lidocaine HCl 5 mg/g Gel — the drug itself is identical. NDC 51316-0022-15 is the 170 g package, while NDC 51316-0022-20 is the 567 g package.
What NDC number is used to bill for this package of CVS Health Sunburn Relief Cooling Lidocaine 0.5 Pain-Relieving Lidocaine HCl 5 mg/g Gel?
Bill NDC 51316-0022-15 — the 11-digit billing format is 51316002215. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 51316-022-15, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 51316-0022-15, written without dashes as 51316002215. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 51316-0022-15, the first segment (51316) is the labeler code FDA assigned to CVS Pharmacy; the middle segment (0022) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (15) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by CVS Pharmacy. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 567 g (51316-0022-20). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
CVS Pharmacy is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 23 words ▾

Uses For the temporary relief of pain and itching associated with sunburn, minor burns, minor cuts, scrapes, insect bites & minor skin irritations.

⏱️ Dosage and Administration 29 words ▾

Directions Adults and children 2 years and older: apply to affected area not more than 3 to 4 times daily. Children under 2 years of age: ask a doctor.

⚠️ Warnings 5 words ▾

Warnings For external use only

📦 Storage and Handling 6 words ▾

Other information May stain some fabrics.

🧪 Active Ingredient 7 words ▾

Active ingredients Lidocaine 0.5% (as Lidocaine HCl)

🧪 Inactive Ingredients 17 words ▾

Inactive ingredients Aloe Barbadensis Leaf Juice, Benzophenone-4, Benzyl Alcohol, Blue 1, Carbomer, Isoceteth-20, Phenoxyethanol, Tetrasodium EDTA, Triethanolamine.

🎯 Purpose 3 words ▾

Purpose External Analgesic

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 51316-0021-96 · CVS 51316-0024-11 · CVS →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.