Home › NDC Lookup › Ingredients › Selenium Sulfide › 51316-0387-01
CVS Health MAXIMUM STRENGTH Dandruff Anti-Seborrheic Dermatitis, anti-dandruff Selenium sulfide 10 mg/mL Shampoo, 325 mL — NDC 51316-0387-01 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

CVS Health MAXIMUM STRENGTH Dandruff Anti-Seborrheic Dermatitis, anti-dandruff Selenium sulfide 10 mg/mL Shampoo, 325 mL — NDC 51316-387-01 (Billing 51316-0387-01)

by CVS Health · 325 mL in 1 BOTTLE

This is a package of 325 mL of CVS Health MAXIMUM STRENGTH Dandruff Anti-Seborrheic Dermatitis, anti-dandruff Selenium sulfide 10 mg/mL Shampoo from CVS Health, marketed since Aug 2024 and currently FDA-listed. It is this product's only package size.

NDC 51316-0387-01
🏷️ FDA NDC (as labeled) 51316-387-01 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 51316-387-01
Product NDC 51316-387
11-digit billing NDC 51316038701
RxCUI 204642
UNII Z69D9E381Q
Application # M032
SPL Set ID cff51af6-84de-4ba5-ac99-9bc42a65c9a5
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2024-08-28
Route TOPICAL
Dosage form SHAMPOO
Substance SELENIUM SULFIDE
Quick answers
  • RxCUI (RxNorm): 204642
Why two NDCs? The FDA registers this code as 51316-387-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 51316-0387-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Other antifungals for topical use class.

Drug family (ATC) Other antifungals for topical use
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📗 Our plain-language guide HelloPharmacist
  • It's used on the scalp to relieve flaking and itching from dandruff and seborrheic dermatitis. It also helps keep those problems from coming back. Some products also list relief of...
  • Most labels say to use it at least twice a week for best results, or as your doctor directs. Some say you can use it every time you shampoo for maximum control. Check your own prod...
  • Some people get skin irritation, or oily or dry hair and scalp. Hair discoloration and a bit more hair shedding have been reported occasionally. Rinsing thoroughly after use helps...
  • Keep it out of your eyes and away from the genital area, since it can cause irritation and burning. Don't use it on broken or inflamed skin. If you get it in your eyes, rinse well...
📖 Read our full Selenium Sulfide guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
51316-0387-01 You're viewing this Main listing 325 mL in 1 BOTTLE 2024-08-28 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Rugby Anti-Dandruff 10 mg/mL 00536-1995-53 Rugby 207 ml $0.014 — Availability likely —
Leader Medicated Dandruff Anti-Seborrheic Dermatitis, Anti-Dandruff 10 mg/mL 70000-0531-01 Cardinal 207 ml $0.014 — Availability likely —
Walgreens Dandruff and Conditioner Cleansing and Conditioning Anti-dandruff 10 mg/mL 00363-4136-01 Walgreen 325 ml — — FDA listed —
Walgreens Dandruff Maximum Strength Anti-dandruff 10 mg/mL 00363-4139-01 Walgreen 325 ml — — FDA listed —
Walgreens Dandruff With Menthol/Selenium Sulfide Anti-dandruff, anti-seborrheic dermatitis, anti-psoriasis 10 mg/mL 00363-4902-01 Walgreen 325 ml — — FDA listed —
Walgreens Clinical Strength Medicated Dandruff Anti-dandruff, Anti-seborrheic dermatitis 10 mg/mL 00363-9422-01 Walgreen 400 ml — — FDA listed —
Dandruff 10 mg/mL 37808-0816-15 H 420 ml — — FDA listed —
Selsun Blue 2-in-1 1 g/100mL 41167-1651-04 Chattem, 325 ml — — FDA listed —
Selsun Blue Itchy Dry Scalp .01 g/mL 41167-6020-03 Chattem, 325 ml — — FDA listed —
Selsun Blue Moisturizing 1 g/100mL 41167-6032-00 Chattem, 207 ml — — FDA listed —
Selsun Blue Medicated 1 g/100mL 41167-6061-01 Chattem, 325 ml — — FDA listed —
Meijer Medicated Selenium Sulfide Anti-Dandruff 10 mg/mL 41250-0545-01 Meijer 325 ml — — FDA listed —
Dandruff 10 mg/mL 41250-0816-15 Meijer, 420 ml — — FDA listed —
Equate Medicated Dandruff Anti-Dandruff 10 mg/mL 49035-0534-01 Wal-Mart 325 ml — — FDA listed —
GoodSense Medicated Dandruff Anti-Seborrheic Dermatitis, Anti-Dandruff 10 mg/mL 50804-0883-01 GOODSENSE 325 ml — — FDA listed —
CVS Health MAXIMUM STRENGTH Dandruff Anti-Seborrheic Dermatitis, anti-dandruff 10 mg/mLthis 51316-0387-01 CVS 325 ml — — FDA listed —
CVS Health MAXIMUM STRENGTH Dandruff Medicated Anti-Seborrheic Dermatitis, anti-dandruff 10 mg/mL 51316-0719-01 CVS 325 ml — — FDA listed —
FAMILY Wellness MAXIMUM STRENGTH DANDRUFF Anti-dandruff, anti-seborrheic dermatitis, anti-psoriasis 10 mg/mL 55319-0949-01 FAMILY 325 ml — — FDA listed —
CVS Gold 1000 mg/100mL 63148-0209-13 Apollo 400 ml — — FDA listed —
Head and Shoulders Clinical Strength Dandruff Defense Dry Scalp Rescue 1 g/100mL 69423-0523-40 The 400 ml — — FDA listed —
Head and Shoulders Clinical Strength Dandruff Defense Advanced Oil Control 1 g/100mL 69423-0525-40 The 400 ml — — Discontinued —
Head and Shoulders Clinical Strength Dandruff Defense Intensive Itch Relief 1 g/100mL 69423-0526-01 The 2 bottles — — FDA listed —
Head and Shoulders 2in1 Clinical Strength Dandruff Defense Intensive Itch Relief 1 g/100mL 69423-0527-40 The 400 ml — — FDA listed —
Head and Shoulders Clinical Strength Dandruff Defense Sensitive Scalp 1 g/100mL 69423-0642-40 The 400 ml — — Discontinued —
Prosoria Medicated 1.77 g/177mL 71573-0121-12 Nuvothera, 177 ml — — FDA listed —
amazon basics maximum strength dandruff Anti-dandruff 10 mg/mL 72288-0551-01 AMAZON.COM 325 ml — — FDA listed —
Careone Medicated Dandruff 10 mg/mL 72476-0025-03 Retail 325 ml — — FDA listed —
Topco Associates 10 mg/mL 76162-0171-11 Topco 325 ml — — FDA listed —
meijer MEDICATED selenium sulfide Dandruff Anti-dandruff, anti-seborrheic dermatitis, anti-psoriasis 10 mg/mL 79481-0071-01 Meijer 325 ml — — FDA listed —
up and up Moisturizing Anti-dandruff Anti-dandruff, anti-seborrheic dermatitis, anti-psoriasis 10 mg/mL 82442-0308-01 TARGET 355 ml — — FDA listed —
up and up Medicated Anti-dandruff Anti-dandruff, anti-seborrheic dermatitis, anti-psoriasis 10 mg/mL 82442-0384-01 TARGET 355 ml — — FDA listed —
Dermoia Seborrheic Dermatitis Selenium Sulfide 10 mg/mL 83524-0938-00 TREASUREWISE 355 ml — — FDA listed —
Head and Shoulders Clinical Strength Advanced Oil Control 1 g/100mL 84126-0075-01 The 2 bottles — — FDA listed —
Head and Shoulders 2in1 Clinical Strength Dry Scalp Rescue 1 g/100mL 84126-0083-40 The 400 ml — — FDA listed —
Head and Shoulders Clinical Strength Dry Scalp Rescue 1 g/100mL 84126-0108-01 The 2 bottles — — FDA listed —
Head and Shoulders Clinical Strength Cooling Itch Relief 1 g/100mL 84126-0183-01 The 2 bottles — — FDA listed —
Head and Shoulders 2in1 Clinical Strength Cooling Itch Relief 1 g/100mL 84126-0184-40 The 400 ml — — FDA listed —
Seleniumdisulfideanti-Dandruffshampoo 1 g/100g 84778-0080-01 Guangzhou 300 g — — Discontinued —
Easyes Anti Dandruff And Anti Hair Thinning Shamp00 1 g/100mL 85004-0002-01 Qingyuan 200 ml — — FDA listed —
UCHOIZE S2 Balance Anti-Dandruff 1 g/100mL 85724-0001-01 Dreamwise 280 ml — — FDA listed —
Silvagle Selenium Sulfide Anti DandruffShampoo 1 mg/100mg 87806-0001-01 GUANGZHOU 300 mg — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2024
On the market since
Aug 2024
📍
2026
Currently FDA-listed
2 years listed
🔓
·
Generic versions listed
see equivalents
✅Generic appears available

FDA-approved generic versions are listed, and recent pricing/market data suggests they may be available — see Therapeutic equivalents.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerCVS Health
FDA applicationM032 (OTC MONOGRAPH DRUG)
Labeler code51316
First marketedAug 2024
Product typeHuman Otc Drug
Portfolio50 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Ask a Doctor Before Use If 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 20 words ▾

Use for the relief of flaking, and itching associated with dandruff, and seborrheic dermatitis and to help prevent their recurrence.

⏱️ Dosage and Administration 22 words ▾

Directions shake well shampoo, then rinse thoroughly for best results, use at least twice a week or as directed by a doctor.

⚠️ Warnings 86 words ▾

Warnings For external use only. Ask a doctor before using this product if condition covers a large area of the body. When using this product avoid contact with the eyes.

If contact occurs, rinse eyes thoroughly with water. for color-treated or permed hair, rinse thoroughly. Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed. Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

📦 Storage and Handling 6 words ▾

Other information store at room temperature

🧪 Active Ingredient 5 words ▾

Active ingredient Selenium sulfide 1%

🧪 Inactive Ingredients 44 words ▾

Inactive ingredients water, ammonium lauryl sulfate, ammonium laureth sulfate, distearyl phthalic acid amide, cocamide MEA, fragrance, titanium dioxide, dimethicone, hydroxypropyl methylcellulose, citric acid, sodium lauroyl lactylate, aloe barbadensis leaf juice, sodium citrate, sodium chloride, phenoxyethanol, methylchloroisothiazolinone, methylisothiazolinone, blue 1, yellow 10, ext. violet 2.

🎯 Purpose 4 words ▾

Purpose Anti-Seborrheic Dermatitis, anti-dandruff

📄 Ask a Doctor Before Use If 16 words ▾

Ask a doctor before using this product if condition covers a large area of the body.

📄 When Using This Product 24 words ▾

When using this product avoid contact with the eyes. If contact occurs, rinse eyes thoroughly with water. for color-treated or permed hair, rinse thoroughly.

📄 Stop Use and Ask a Doctor If 21 words ▾

Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed.

📄 Keep Out of Reach of Children 20 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

📄 Questions or Comments 4 words ▾

Questions or comments? 1-866-567-8600

📄 Package Label / Principal Display Panel 71 words ▾

PRINCIPAL DISPLAY PANEL - 325 mL Bottle Label CVS Health ® Compare to the active ingredient in Selsun Blue ® Moisturizing Dandruff Shampoo* MAXIMUM STRENGTH Dandruff Shampoo SELENIUM SULFIDE 1% For the relief of seborrheic dermatitis & dandruff symptoms Helps control flakes & itching For healthier-looking hair & scalp MOISTURIZING + ALOE • PARABEN PHTHALATE • FREE 11 FL OZ (325 mL) 05-4270 PRINCIPAL DISPLAY PANEL - 325 mL Bottle Label

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Selenium Sulfide (matched by generic name) — the program that covers self-administered drugs. 2 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Selenium Sulfide. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$190.8K
Claims incl. refills
12.2K
Beneficiaries
9.2K
Spend / beneficiary
$20.82
Spend / claim
$15.64
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for CVS Health MAXIMUM STRENGTH Dandruff Anti-Seborrheic Dermatitis, anti-dandruff (this brand).

Top reported reactions

Pain37
Fatigue32
Nausea32
Pruritus29
Anxiety25
Condition Aggravated25
Headache24

Age at onset

Infant1
Child2
Adolescent3
Adult82
Elderly43

Reporter sex

669 reports
Male · 56%
Female · 44%

Serious outcomes

Hospitalization154
Death23
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 67 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by CVS Health. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
CVS Health is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 51316-0379-43 · CVS 51316-0388-03 · CVS →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.