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Maximum Strength Antacid Mint Simethicone 125 mg Tablet, Chewable, 60-count — NDC 53041-100-23 (Billing 53041-0100-23)

by Guardian Drug Company · 60 TABLET, CHEWABLE in 1 BOTTLE

This is a package of 60 tablets of Maximum Strength Antacid Mint Simethicone 125 mg Tablet, Chewable from Guardian Drug Company, marketed since Jul 2026 and currently FDA-listed. It is this product's only package size.

NDC 53041-0100-23
🏷️ FDA NDC (as labeled) 53041-100-23 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 53041-100-23 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
53041 labeler · 100 product · 23 package
Package marketed since
Jul 13, 2026
Sample package
No — commercial package
Listing certified through
Dec 31, 2027
Barcode (UPC-A, from the NDC)
3 5304110023 0
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 53041-100-23
Product NDC 53041-100
11-digit billing NDC 53041010023
RxCUI 314221
UNII 92RU3N3Y1O
Application # M002
SPL Set ID 48ec3132-17cf-1de9-e063-6294a90aa407
Physiologic effect Skin Barrier Activity
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2026-07-13
Route ORAL
Dosage form TABLET, CHEWABLE
Substance DIMETHICONE
Quick answers
  • RxCUI (RxNorm): 314221
Why two NDCs? The FDA registers this code as 53041-100-23 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 53041-0100-23. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

📗 Our plain-language guide HelloPharmacist
  • It relieves the discomfort of gas. For adults, that means pressure, bloating and fullness. Infant drops are for baby gas, often caused by swallowed air or certain formulas or foods...
  • Shake the bottle well. Use only the syringe or dropper that came with it. Dispense it slowly toward the inner cheek. You can also mix it with 1 oz. of cool water, formula or anothe...
  • Doses can be repeated as needed after meals and at bedtime. Do not go over 12 doses in a day. Follow your product’s label and your doctor’s advice.
  • If you can, use your child’s weight. If not, use age. Check the chart on your product, and ask me or your doctor if you are unsure.
📖 Read our full Simethicone guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
53041-0100-23 You're viewing this Main listing 60 TABLET, CHEWABLE in 1 BOTTLE 2026-07-13 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
gas relief 125 mg 62011-0189-01 Strategic 9 tablets $0.097 — FDA listed —
Foster and Thrive Extra Strength Gas Relief Cherry 125 mg 70677-1077-01 Strategic 9 tablets $0.103 — Availability likely —
Rugby Gas relief 125 mg 00536-1223-08 Rugby 60 tablets $0.103 — Availability likely —
extra strength Gas Relief cherry creme 125 mg 46122-0811-08 Amerisource 9 tablets $0.103 — Availability likely —
Simethicone 125 mg 17714-0040-60 Advance 60 tablets — — FDA listed —
Gas Relief 125 mg 21130-0135-73 Safeway 9 tablets — — FDA listed —
Mylanta Gas Minis Mint Flavor 125 mg 62372-0800-50 Infirst 50 tablets — — FDA listed —
Mylanta Gas Minis Assorted Fruit Flavor 125 mg 62372-0801-03 Infirst 3 tablets — — Discontinued —
Extra Strength Gas Relief Cherry 125 mg 50804-0134-73 Good 9 tablets — — FDA listed —
Wonderbelly Extra Strength Anti-Gas 125 mg 82431-0203-02 Ginger 2 tablets — — Discontinued —
Pepto Gas plus Bloating 125 mg 84126-0378-16 The 16 tablets — — FDA listed —
Gas Relief 125 mg 11822-6080-02 Rite 12 tablets — — FDA listed —
Gas-Aid 125 mg 69626-7197-03 Leosons 9 tablets — — FDA listed —
Gas Relief 125 mg 36800-0122-73 Topco 6 tablets — — FDA listed —
Extra Strength Gas Relief 125 mg 42507-0701-34 Hyvee 9 tablets — — FDA listed —
Wonderbelly Extra Strength Anti-Gas 125 mg 82431-0201-02 Ginger 2 tablets — — Discontinued —
Wonderbelly Extra Strength Anti-Gas 125 mg 82431-0202-02 Ginger 2 tablets — — Discontinued —
HEB Gas Relief Extra Strength Peppermint 125 mg 37808-0155-73 H 9 tablets — — FDA listed —
Extra Strength Gas Relief Cherry Creme 125 mg 51316-0134-13 CVS 9 tablets — — FDA listed —
Family Wellness Extra Strength Gas Relief Cherry 125 mg 55319-0134-34 Family 12 tablets — — FDA listed —
Extra Strength Gas Relief 125 mg 57896-0694-03 Geri-Care 30 tablets — — FDA listed —
Simethicone 125 mg 82804-0152-09 Proficient 9 tablets — — FDA listed —
Gas Relief - Cherry Flavor 125 mg 11673-0066-48 TARGET 12 tablets — — FDA listed —
Extra Strength Gas Relief Cherry 125 mg 37808-0692-13 H 12 tablets — — FDA listed —
Extra Strength Gas Relief Cherry Flavor 125 mg 53943-0134-39 Discount 9 tablets — — FDA listed —
Gas Relief 125 mg 80136-0859-68 Heartland 100 tablets — — FDA listed —
Extra Strength Simethicone 125 mg 37835-0233-18 Bi-Mart 9 tablets — — FDA listed —
Gas Relief Extra Strength 125 mg 55301-0680-44 ARMY 9 tablets — — FDA listed —
Gas Relief 125 mg 79481-0608-04 Meijer 9 tablets — — FDA listed —
QCH Extra Strength Gas Relief Cherry Flavor 134CHR 125 mg 83324-0132-18 Chain 9 tablets — — FDA listed —
gas relief 125 mg 41163-0408-44 United 9 tablets — — FDA listed —
Extra Strength Gas Relief Cherry 125 mg 69256-0134-73 Harris 9 tablets — — FDA listed —
Gas Relief 125 mg 83324-0325-18 Chain 9 tablets — — FDA listed —
Extra Strength Gas Relief 125 mg 69256-0135-73 Harris 9 tablets — — FDA listed —
Simethicone 125 mg 69618-0032-06 Reliable 60 tablets — — FDA listed —
Extra Strength Gas Relief Cherry 125 mg 72476-0134-73 Retail 9 tablets — — FDA listed —
Simethicone 125 mg 17856-0137-01 ATLANTIC 1 tablet — — FDA listed —
Maximum Strength Antacid Mint 125 mgthis 53041-0100-23 Guardian 60 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2026
On the market since
Jul 2026
📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII IY9XDZ35W2
    Dextrose is a simple sugar derived from corn or other sources. It serves as a filler and sweetener in medicines to add bulk, improve taste, and help stabilize the medication's form.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
  • UNII 7CVR7L4A2D
    A starch-derived carbohydrate produced by breaking down corn, potato, or tapioca starch. It functions as a filler and binder to give the medicine bulk and texture, and sometimes as a mild sweetener or texture enhancer in powders and tablets.
  • UNII OP1R32D61U
    Microcrystalline cellulose is a purified form of cellulose, a natural fiber from plant sources. It acts as a binder and filler in tablets and capsules, helping hold ingredients together and give the medicine its shape and size.
  • UNII 506T60A25R
    Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.
  • UNII C151H8M554
    A natural sugar derived from sugar cane or sugar beets. It's used as a sweetener, filler, and binder to improve taste, add bulk, and help hold tablet or capsule ingredients together.

6 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescompressible sugar, dextrose, flavor, magnesium stearate, maltodextrin, microcrystalline cellulose, sorbitol.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerGuardian Drug Company
FDA applicationM002 (OTC MONOGRAPH DRUG)
Labeler code53041
First marketedJul 2026
Product typeHuman Otc Drug
Portfolio46 products on file

More NDCs from Guardian Drug Company labeler code 53041

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 9 words ▾

USE(S) relieves: pressure bloating symptoms referred to as gas

⏱️ Dosage and Administration 33 words ▾

DIRECTIONS chew 1 to 2 tablets thoroughly as needed after meals and at bedtime do not exceed 4 tablets in a 24 hour period except under the advice and supervision of a physician

⚠️ Warnings 2 words ▾

WARNINGS .

📦 Storage and Handling 27 words ▾

OTHER INFORMATION do not use if inner seal is broken store at room temperature avoid high humidity and excessive heat, above 40 o C (104 o F)

🧪 Active Ingredient 7 words ▾

ACTIVE INGREDIENT(in each tablet) Simethicone 125 mg

🧪 Inactive Ingredients 12 words ▾

INACTIVE INGREDIENTS compressible sugar, dextrose, flavor, magnesium stearate, maltodextrin, microcrystalline cellulose, sorbitol.

🎯 Purpose 2 words ▾

PURPOSE Anti-gas

📄 Keep Out of Reach of Children 27 words ▾

KEEP OUT OF REACH OF CHILDREN Keep out of the reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

📄 Package Label / Principal Display Panel 23 words ▾

PRINCIPAL DISPLAY PANEL Guardian Maximum Strength Antacid Mint Flavor Simethicone 125 mg/Anti-gas Relieves Symptoms of Gas 60 Chewable Tablets (125 mg Ea.) 131-60-gdc.jpg

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Maximum Strength Antacid Mint (this brand).

Top reported reactions

Nausea107
Fatigue83
Diarrhoea79
Vomiting71
Abdominal Pain68
Dyspnoea67
Pain59

Reporter sex

0 reports
Male · 48%
Female · 51%
Unknown · 0%

Serious outcomes

Hospitalization570
Death150
Disabling30
Reports over time (by year) — tap or hover for the count & year
2021 2022 2024 2026 10 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Guardian Drug Company. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Guardian Drug Company is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 53041-0098-17 · Guardian 53041-0102-13 · Guardian →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.