Mucinex D Guaifenesin and Pseudoephedrine Hydrochloride 600 mg; 60 mg Tablet, Extended Release — NDC 63824-0057-36 package photo

Mucinex D Guaifenesin and Pseudoephedrine Hydrochloride 600 mg; 60 mg Tablet, Extended Release

by Reckitt Benckiser LLC · 4 BLISTER PACK in 1 CARTON (63824-057-36) / 9 TABLET, EXTENDED RELEASE in 1 BLISTER PACK
NDC 63824-0057-36
🏷️ FDA NDC (as labeled) 63824-057-36 billing pads the product segment with a zero
This package
Contains9 tablet, extended release in 1 blister pack Cost per ea$0.7035 NADAC Per package$25.33 / 36 tablets Pack sizes2 compare ↓
Also comes in: 18 tablets 63824-0057-18
OTC Brand On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

🆔 Identity & classification

FDA NDC (as labeled) 63824-057-36
Product NDC 63824-057
11-digit billing NDC 63824005736
NCPDP billing unit EA — each (per item)
RxCUI 1305603
UNII 495W7451VQ, 6V9V2RYJ8N
UPC 0363824057187
Application # NDA021585
SPL Set ID d5f046c0-66b9-4cdc-9a1e-8e2cb5ece84f
Established class (EPC) Expectorant
Physiologic effect Decreased Respiratory Secretion Viscosity; Increased Respiratory Secretions
DEA schedule Non-controlled
Marketing category NDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2012-06-26
Route ORAL
Dosage form TABLET, EXTENDED RELEASE
Substance GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
GPI-14 43996202307435
GPI class Mucinex D
GCN Seq No 012073
GCN 54980
HICL code 000270
Ingredient (HICL) Guaifenesin/Pseudoephedrne Hcl
HIC1 code B
Therapeutic class — broad (HIC1) Respiratory System
HIC2 code B4
Therapeutic class — intermediate (HIC2) Drugs Affecting The Trachea And Bronchi (Contin.1)
HIC3 code B4W
Therapeutic class — specific (HIC3) Decongestant-Expectorant Combinations
AHFS code 12:12.12.00
AHFS class Alpha- And Beta-Adrenergic Agonists
FDB label name MUCINEX D ER 600-60 MG TABLET
FDB brand name Mucinex D
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 63824-057-36 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 63824-0057-36. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Expectorant class.

Pharmacologic class Expectorant
Drug family (ATC) Expectorants
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerReckitt Benckiser LLC
Application holderRECKITT BENCKISER LLC
FDA applicationNDA021585 (NDA)
Labeler code63824
First marketedJun 2012
Product typeHuman Otc Drug
Portfolio174 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name MUCINEX D ER 600-60 MG TABLET Ingredient Guaifenesin/Pseudoephedrne Hcl
📖 What it is MedlinePlus · NLM

Guaifenesin is used to relieve chest congestion. Guaifenesin may help control symptoms but does not treat the cause of symptoms or speed recovery. Guaifenesin is in a class of medications called expectorants. It works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Yes, each ingredient does something different. Guaifenesin works on your chest — it thins and loosens the mucus in your airways so it's easier to cough up. Pseudoephedrine works on...
  • What does this medicine actually do — do I need both ingredients?
  • No — please don't. Extended-release tablets are designed to release the medicine slowly over about 12 hours. Crushing, chewing, or breaking them releases the whole dose at once, wh...
  • Can I crush or cut the extended-release tablet if it's hard to swallow?
📖 Read our full Guaifenesin / Pseudoephedrine guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color orange / white
ShapeOval
ImprintMucinex;600
Size16 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII LMI26O6933
    Alumina is a white powder form of aluminum oxide. It's used as a filler to add bulk to tablets and capsules, and sometimes as a thickening or anti-caking agent in powdered formulations.
  • UNII HHT01ZNK31
    Carbomer Homopolymer Type B is a synthetic polymer made from acrylic acid. It absorbs water and forms a gel, so it's used in medicines as a thickener, suspending agent, and to help create a smooth texture in creams, gels, and lotions.
  • UNII H77VEI93A8
    A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
  • UNII 3NXW29V3WO
    Hypromellose is a plant-based thickener made from cellulose. It's used in medicines as a binder to hold ingredients together, a coating for tablets, and a thickener for liquids.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
  • UNII OP1R32D61U
    Microcrystalline cellulose is a purified form of cellulose, a natural fiber from plant sources. It acts as a binder and filler in tablets and capsules, helping hold ingredients together and give the medicine its shape and size.

6 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescarbomer homopolymer type B; FD&C yellow no. 6 aluminum lake; hypromellose, USP; magnesium stearate, NF; microcrystalline cellulose, NF; sodium starch glycolate, NF

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMedingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.704 $25.33 / 36 tablets
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Dec 2021 Mar 2022 Apr 2022 Jan 2024 $0.704 $0.614
▲ Up 12% over the last 5 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 70677-1011-01 Strategic 18 tablets $0.357 FDA listed save 49%
mucus D 600 mg/1; 60 mg 00113-8307-68 L. 18 tablets $0.387 Availability likely save 45%
Guaifenesin D 600 mg/1; 60 mg 00536-1333-21 RUGBY 18 tablets $0.387 Availability likely save 45%
Rugby Mucus Relief D 600 mg/1; 60 mg 00536-1449-21 Rugby 18 tablets $0.387 Availability likely save 45%
Leader Mucus Relief D 600 mg/1; 60 mg 70000-0720-01 Cardinal 18 tablets $0.387 Availability likely save 45%
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 70677-1263-01 Strategic 18 tablets $0.387 Availability likely save 45%
foster and thrive mucus relief d 600 mg/1; 60 mg 70677-1272-01 Strategic 18 tablets $0.387 Availability likely save 45%
Mucinex D 600 mg/1; 60 mgthis 63824-0057-36 Reckitt 9 tablets $0.704 FDA listed
Guaifenesin and Pseudoephedrine Hydrochloride 600 mg/1; 60 mg 00363-0077-18 WALGREEN 18 tablets FDA listed
Mucus Relief D 600 mg/1; 60 mg 00363-1604-15 Walgreens 18 tablets FDA listed
Mucus Relief D 600 mg/1; 60 mg 00363-8708-68 Walgreen 18 tablets FDA listed
Guaifenesin D 600 mg/1; 60 mg 00363-9930-18 Walgreen 18 tablets FDA listed
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 00363-9946-40 WALGREEN 18 tablets FDA listed
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 11822-0046-01 Rite 18 tablets FDA listed
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 30142-0137-12 KROGER 18 tablets FDA listed
mucus d 600 mg/1; 60 mg 30142-0739-68 Kroger 18 tablets FDA listed
Guaifenesin and Pseudoephedrine Hydrochloride 600 mg/1; 60 mg 41415-0994-18 PUBLIX 18 tablets FDA listed
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 46122-0801-08 Amerisource 18 tablets FDA listed
Mucinex D 600 mg/1; 60 mg 50090-1075-00 A-S 18 tablets FDA listed
Mucinex D 600 mg/1; 60 mg 50090-1076-00 A-S 9 tablets FDA listed
Mucus D 600 mg/1; 60 mg 51316-0878-68 CVS 18 tablets FDA listed
Guaifenesin D 600 mg/1; 60 mg 51316-0993-18 CVS 18 tablets FDA listed
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 51660-0074-18 Ohm 18 tablets FDA listed
Guaifenesin and Pseudoephedrine HCL 600 mg/1; 60 mg 55111-0798-09 Dr. 9 tablets FDA listed
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 58602-0833-12 Aurohealth 18 tablets FDA listed
mucus relief d 600 mg/1; 60 mg 59640-0621-89 H 18 tablets FDA listed
Guaifenesin and Pseudoephedrine Hydrochloride 600 mg/1; 60 mg 62011-0475-01 STRATEGIC 18 tablets FDA listed
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 62207-0827-72 Granules 10 tablets FDA listed
Mucus D 600 mg/1; 60 mg 69842-0095-18 CVS 18 tablets FDA listed
Mucus D 600 mg/1; 60 mg 79481-0709-01 Meijer, 18 tablets FDA listed
Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 79481-1002-01 Meijer 18 tablets FDA listed
equate mucus d 600 mg/1; 60 mg 79903-0125-18 WALMART 18 tablets Discontinued
topcare mucus d 600 mg/1; 60 mg 76162-0801-89 Topco 1 tablet FDA listed
About this product: this is the brand-name version. FDA-approved generic versions are listed, and recent pricing/market data suggests they may be available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2012
On the market since
Jun 2012
📍
2026
Currently FDA-listed
14 years listed
🔓
·
Generic versions listed
see equivalents
Generic appears available

FDA-approved generic versions are listed, and recent pricing/market data suggests they may be available — see Therapeutic equivalents.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Mucinex D (this brand).

Top reported reactions

Insomnia110
Fatigue102
Dizziness99
Headache98
Nausea97
Dyspnoea83
Cough72

Age at onset

Adolescent1
Adult90
Elderly78

Reporter sex

0 reports
Male · 31%
Female · 69%

Serious outcomes

Hospitalization208
Death57
Life-threatening11
Reports over time (by year) — tap or hover for the count & year
2022 2023 2024 2026 81 27
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Per unit Per pack Marketing startStatus
63824-0057-18 1 BLISTER PACK in 1 CARTON (63824-057-18) / 18 TABLET, EXTENDED RELEASE in 1 BLISTER PACK $0.7035 / ea $12.66 2012-06-26 Active
63824-0057-36 You're viewing this 4 BLISTER PACK in 1 CARTON (63824-057-36) / 9 TABLET, EXTENDED RELEASE in 1 BLISTER PACK $0.7035 / ea $25.33 2012-06-26 Active

This pack effectively ties for the lowest per-ea cost of the 2 priced pack sizes ($0.7035 NADAC).

Pack size FAQ

What quantity is in NDC 63824-0057-36?
NDC 63824-0057-36 is listed by the FDA — 4 blister pack in 1 carton / 9 tablet, extended release in 1 blister pack.
What NDC number is used to bill for this package of Mucinex D Guaifenesin and Pseudoephedrine Hydrochloride 600 mg; 60 mg Tablet, Extended Release?
Bill NDC 63824-0057-36 — the 11-digit billing format is 63824005736. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage 53 words

Uses helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves nasal congestion due to: common cold hay fever upper respiratory allergies temporarily restores freer breathing through the nose promotes nasal and/or sinus drainage temporarily relieves sinus congestion and pressure

⏱️ Dosage and Administration 58 words

Directions do not crush, chew, or break extended-release tablet take with a full glass of water this product can be administered without regard for timing of meals adults and children 12 years and older: 2 extended-release tablets every 12 hours; not more than 4 extended-release tablets in 24 hours children under 12 years of age: do not use

⚠️ Warnings 182 words

Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough accompanied by too much phlegm (mucus) When using this product do not use more than directed Stop use and ask a doctor if you get nervous, dizzy, or sleepless symptoms do not get better within 7 days, come back or occur with a fever, rash, or persistent headache.

These could be signs of a serious illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 25 words

Other information tamper evident: do not use if carton is open or if printed seal on blister is broken or missing store at 20-25°C (68-77°F)

🧪 Active Ingredient 17 words

Active ingredients (in each extended-release tablet) Purposes Guaifenesin 600 mg Expectorant Pseudoephedrine HCl 60 mg Nasal Decongestant

🧪 Inactive Ingredients 24 words

Inactive ingredients carbomer homopolymer type B; FD&C yellow no. 6 aluminum lake; hypromellose, USP; magnesium stearate, NF; microcrystalline cellulose, NF; sodium starch glycolate, NF

🎯 Purpose 17 words

Active ingredients (in each extended-release tablet) Purposes Guaifenesin 600 mg Expectorant Pseudoephedrine HCl 60 mg Nasal Decongestant

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.