Mucus Relief D guaifenesin and pseudoephedrine hydrochloride 600 mg; 60 mg Tablet, Multilayer, Extended Release
by Walgreen Company · 2 BLISTER PACK in 1 CARTON (0363-8708-68) / 18 TABLET, MULTILAYER, EXTENDED RELEASE in 1 BLISTER PACK
NDC 00363-8708-68
🏷️ FDA NDC (as labeled)
0363-8708-68
billing pads the labeler segment with a zero
OTC
Generic
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
0363-8708-68
Product NDC
0363-8708
11-digit billing NDC
00363870868
RxCUI
1305603
UNII
495W7451VQ, 6V9V2RYJ8N
Application #
ANDA214407
SPL Set ID
915ca26a-d5d1-40f8-980d-415926e45656
Established class (EPC)
Expectorant
Physiologic effect
Decreased Respiratory Secretion Viscosity; Increased Respiratory Secretions
DEA schedule
Non-controlled
Marketing category
ANDA
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2024-03-26
Route
ORAL
Dosage form
TABLET, MULTILAYER, EXTENDED RELEASE
Substance
GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
GPI-14
43996202307435
Why two NDCs?
The FDA registers this code as 0363-8708-68 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00363-8708-68. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Expectorant class.
Pharmacologic class
Expectorant
Drug family (ATC)
Expectorants
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerWalgreen Company
Application holderL PERRIGO CO
FDA applicationANDA214407 (ANDA)
Labeler code00363
First marketedMar 2024
Product typeHuman Otc Drug
Portfolio468 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
📖 What it is MedlinePlus · NLM
Guaifenesin is used to relieve chest congestion. Guaifenesin may help control symptoms but does not treat the cause of symptoms or speed recovery. Guaifenesin is in a class of medications called expectorants. It works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.
Read the full MedlinePlus article ↗📗 Our plain-language guide HelloPharmacist
- Yes, each ingredient does something different. Guaifenesin works on your chest — it thins and loosens the mucus in your airways so it's easier to cough up. Pseudoephedrine works on...
- What does this medicine actually do — do I need both ingredients?
- No — please don't. Extended-release tablets are designed to release the medicine slowly over about 12 hours. Crushing, chewing, or breaking them releases the whole dose at once, wh...
- Can I crush or cut the extended-release tablet if it's hard to swallow?
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about guaifenesin and pseudoephedrine hydrochloride?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
Color
Orange
ShapeOval
ImprintL6
Size17 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII HHT01ZNK31
Carbomer Homopolymer Type B is a synthetic polymer made from acrylic acid. It absorbs water and forms a gel, so it's used in medicines as a thickener, suspending agent, and to help create a smooth texture in creams, gels, and lotions.
-
UNII H77VEI93A8
A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
-
UNII 3NXW29V3WO
Hypromellose is a plant-based thickener made from cellulose. It's used in medicines as a binder to hold ingredients together, a coating for tablets, and a thickener for liquids.
-
UNII 70097M6I30
Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
-
UNII OP1R32D61U
Microcrystalline cellulose is a purified form of cellulose, a natural fiber from plant sources. It acts as a binder and filler in tablets and capsules, helping hold ingredients together and give the medicine its shape and size.
-
UNII ETJ7Z6XBU4
Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
6 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statescarbomer homopolymer type B, colloidal silicon dioxide, FD&C yellow #6 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per each | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 70677-1011-01 | Strategic | 18 tablets | $0.357 | — | FDA listed | — |
| mucus D 600 mg/1; 60 mg 00113-8307-68 | L. | 18 tablets | $0.387 | — | Availability likely | — |
| Guaifenesin D 600 mg/1; 60 mg 00536-1333-21 | RUGBY | 18 tablets | $0.387 | — | Availability likely | — |
| Rugby Mucus Relief D 600 mg/1; 60 mg 00536-1449-21 | Rugby | 18 tablets | $0.387 | — | Availability likely | — |
| Leader Mucus Relief D 600 mg/1; 60 mg 70000-0720-01 | Cardinal | 18 tablets | $0.387 | — | Availability likely | — |
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 70677-1263-01 | Strategic | 18 tablets | $0.387 | — | Availability likely | — |
| foster and thrive mucus relief d 600 mg/1; 60 mg 70677-1272-01 | Strategic | 18 tablets | $0.387 | — | Availability likely | — |
| Mucinex D 600 mg/1; 60 mg 63824-0057-18 | Reckitt | 18 tablets | $0.704 | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine Hydrochloride 600 mg/1; 60 mg 00363-0077-18 | WALGREEN | 18 tablets | — | — | FDA listed | — |
| Mucus Relief D 600 mg/1; 60 mg 00363-1604-15 | Walgreens | 18 tablets | — | — | FDA listed | — |
| Mucus Relief D 600 mg/1; 60 mgthis 00363-8708-68 | Walgreen | 18 tablets | — | — | FDA listed | — |
| Guaifenesin D 600 mg/1; 60 mg 00363-9930-18 | Walgreen | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 00363-9946-40 | WALGREEN | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 11822-0046-01 | Rite | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 30142-0137-12 | KROGER | 18 tablets | — | — | FDA listed | — |
| mucus d 600 mg/1; 60 mg 30142-0739-68 | Kroger | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine Hydrochloride 600 mg/1; 60 mg 41415-0994-18 | PUBLIX | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 46122-0801-08 | Amerisource | 18 tablets | — | — | FDA listed | — |
| Mucinex D 600 mg/1; 60 mg 50090-1075-00 | A-S | 18 tablets | — | — | FDA listed | — |
| Mucinex D 600 mg/1; 60 mg 50090-1076-00 | A-S | 9 tablets | — | — | FDA listed | — |
| Mucus D 600 mg/1; 60 mg 51316-0878-68 | CVS | 18 tablets | — | — | FDA listed | — |
| Guaifenesin D 600 mg/1; 60 mg 51316-0993-18 | CVS | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 51660-0074-18 | Ohm | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine HCL 600 mg/1; 60 mg 55111-0798-09 | Dr. | 9 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 58602-0833-12 | Aurohealth | 18 tablets | — | — | FDA listed | — |
| mucus relief d 600 mg/1; 60 mg 59640-0621-89 | H | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine Hydrochloride 600 mg/1; 60 mg 62011-0475-01 | STRATEGIC | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 62207-0827-72 | Granules | 10 tablets | — | — | FDA listed | — |
| Mucus D 600 mg/1; 60 mg 69842-0095-18 | CVS | 18 tablets | — | — | FDA listed | — |
| Mucus D 600 mg/1; 60 mg 79481-0709-01 | Meijer, | 18 tablets | — | — | FDA listed | — |
| Guaifenesin and Pseudoephedrine HCl 600 mg/1; 60 mg 79481-1002-01 | Meijer | 18 tablets | — | — | FDA listed | — |
| equate mucus d 600 mg/1; 60 mg 79903-0125-18 | WALMART | 18 tablets | — | — | Discontinued | — |
| topcare mucus d 600 mg/1; 60 mg 76162-0801-89 | Topco | 1 tablet | — | — | FDA listed | — |
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2024
On the market since
Mar 2024
📍
2026
Currently FDA-listed
2 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug
This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for mucus relief d (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 28%
Female · 72%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 00363-8708-68 You're viewing this | 2 BLISTER PACK in 1 CARTON (0363-8708-68) / 18 TABLET, MULTILAYER, EXTENDED RELEASE in 1 BLISTER PACK | 2024-03-26 | Active |
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 0363-8708-68, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 00363-8708-68, written without dashes as 00363870868. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 00363-8708-68, the first segment (00363) is the labeler code FDA assigned to Walgreen Company; the middle segment (8708) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (68) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Walgreen Company. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Walgreen Company is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses • helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies • temporarily restores freer breathing through the nose • promotes nasal and/or sinus drainage • temporarily relieves sinus congestion and pressure
⏱️ Dosage and Administration ▾
Directions • do not crush, chew, or break tablet • take with a full glass of water • this product can be administered without regard for timing of meals • adults and children 12 years and older: 2 tablets every 12 hours; not more than 4 tablets in 24 hours • children under 12 years of age: do not use
⚠️ Warnings ▾
Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have • heart disease • high blood pressure • thyroid disease • diabetes • trouble urinating due to an enlarged prostate gland • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema • cough accompanied by too much phlegm (mucus) When using this product • do not use more than directed Stop use and ask a doctor if • you get nervous, dizzy, or sleepless • symptoms do not get better within 7 days, come back or occur with a fever, rash, or persistent headache.
These could be signs of a serious illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.
In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).
🧪 Active Ingredient ▾
Active ingredients (in each extended-release bi-layer tablet) Guaifenesin 600 mg Pseudoephedrine HCl 60 mg
🧪 Inactive Ingredients ▾
Inactive ingredients carbomer homopolymer type B, colloidal silicon dioxide, FD&C yellow #6 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate
🎯 Purpose ▾
Purposes Expectorant Nasal Decongestant
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.