Home › NDC Lookup › Ingredients › Purified Water › 72598-0022-01
Plus Rinse Emergency Eyewash Purified Water 99.1 mL/100mL Liquid, 1000 mL — NDC 72598-0022-01 package photo

Plus Rinse Emergency Eyewash Purified Water 99.1 mL/100mL Liquid, 1000 mL

by INNOVATIVE SAFETY SUPPLY INC. · 1000 mL in 1 BOTTLE (72598-022-01)
NDC 72598-0022-01
🏷️ FDA NDC (as labeled) 72598-022-01 billing pads the product segment with a zero
This package
Contains1000 mL Pack sizes3 compare ↓
Also comes in: 200 ml 72598-0022-02 500 ml 72598-0022-20
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 72598-022-01
Product NDC 72598-022
11-digit billing NDC 72598002201
RxCUI 1053429
UNII 059QF0KO0R
Application # M018
SPL Set ID b3f47d26-39e4-4aea-bb92-358def52b652
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2019-05-06
Route OPHTHALMIC
Dosage form LIQUID
Substance WATER
Why two NDCs? The FDA registers this code as 72598-022-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 72598-0022-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerINNOVATIVE SAFETY SUPPLY INC.
FDA applicationM018 (OTC MONOGRAPH DRUG)
Labeler code72598
First marketedMay 2019
Product typeHuman Otc Drug
Portfolio2 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📗 Our plain-language guide HelloPharmacist
  • It can seem a little odd at first. In these products, sterile water plays the essential role of carrying or dissolving the actual active medication — like insulin — so it can be sa...
  • Why is 'water' listed as the active ingredient on my medicine?
  • No — these are very different products that should never be used interchangeably. Sterile Water for Injection is used only as a diluent for other drugs given by needle, and it must...
  • Is Sterile Water for Injection the same as the eye wash or the irrigation product?
📖 Read our full Water guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 200 ml 500 ml
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Rugby Eye Wash 99.05 g/100mL 00536-1224-97 Rugby 1 bottle $0.030 — Availability likely —
Leader Eye Wash 99.05 g/100mL 70000-0018-01 Cardinal 1 bottle $0.030 — Availability likely —
Quality Choice Eye Wash 99.05 g/100mL 83324-0192-04 Chain 1 bottle $0.030 — Availability likely —
Walgreens Sterile Soothing Eye Wash 99.05 mL/100mL 00363-0700-04 Walgreens 1 bottle — — FDA listed —
Rite Aid Eye Wash 99.05 g/100mL 11822-2313-01 Rite 1 bottle — — FDA listed —
Eye Wash 99.05 mL/100mL 11822-9860-08 Rite 1 bottle — — FDA listed —
Advanced Eye Relief Eye Wash 99.05 mL/100mL 24208-0005-04 Bausch 1 applicator — — FDA listed —
Eye Wash 99.05 mL/100mL 30142-0010-18 Kroger 1 bottle — — FDA listed —
Eye Wash 991 mg/mL 49687-0010-01 CMC 1 tube — — FDA listed —
Rugby Eye Wash 99.05 g/100mL 50090-7440-00 A-S 1 bottle — — FDA listed —
Medics Choice Soothing Eye Wash 99.05 g/100mL 55651-0555-01 KC 118 ml — — FDA listed —
Eye Wash 99.05 mL/100mL 59779-0337-09 CVS 1 bottle — — FDA listed —
Plus Rinse Emergency Eyewash 99.1 mL/100mLthis 72598-0022-01 INNOVATIVE 1000 ml — — FDA listed —
Eye Wash 991 mg/mL 82001-0001-00 Jiangxi 30 ml — — FDA listed —
Eye Wash 991 mg/mL 82996-0007-01 Hubei 15 ml — — FDA listed —
Eye Wash 99.1 mL/100mL 84219-0007-15 M-star 15 ml — — FDA listed —
Huanggang Eye Wash 99 mL/100mL 85426-0002-01 Huanggang 15 ml — — Discontinued —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2019
On the market since
May 2019
📍
2026
Currently FDA-listed
7 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
72598-0022-20 500 mL in 1 BOTTLE (72598-022-20) 2019-05-06 Active
72598-0022-01 You're viewing this 1000 mL in 1 BOTTLE (72598-022-01) 2019-05-06 Active
72598-0022-02 200 mL in 1 BOTTLE (72598-022-02) 2019-05-06 Active

You're viewing the largest of 3 pack sizes for this product.

Pack size FAQ

What quantity is in NDC 72598-0022-01?
NDC 72598-0022-01 contains 1000 mL — 1000 ml in 1 bottle.
What is the difference between NDC 72598-0022-01 and NDC 72598-0022-02?
Both are Plus Rinse Emergency Eyewash Purified Water 99.1 mL/100mL Liquid — the drug itself is identical. NDC 72598-0022-01 is the 1000 mL package, while NDC 72598-0022-02 is the 200 ml package.
What NDC number is used to bill for this package of Plus Rinse Emergency Eyewash Purified Water 99.1 mL/100mL Liquid?
Bill NDC 72598-0022-01 — the 11-digit billing format is 72598002201. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 72598-022-01, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 72598-0022-01, written without dashes as 72598002201. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 72598-0022-01, the first segment (72598) is the labeler code FDA assigned to INNOVATIVE SAFETY SUPPLY INC.; the middle segment (0022) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by INNOVATIVE SAFETY SUPPLY INC.. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 200 ml (72598-0022-02), 500 ml (72598-0022-20). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
INNOVATIVE SAFETY SUPPLY INC. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 17 words ▾

Uses For rinsing the eyes to reduce risk of severe injury caused by chemicals or particulate contamination

⏱️ Dosage and Administration 87 words ▾

Directions do not dilute solution or reuse bottle use only unopened bottle to open, twist cap in the direction of the arrow avoid contamination of the integrated eyecup place integrated eyecup over affected eye(s) tilt head backward open eyelid(s) wide control rate of flow by pressure on bottle thoroughly bathe eye(s) with solution allow solution to flow away from eye(s) rinse until the bottle is empty and continue rinsing with Plum Emergency Eyewash until you reach a doctor continue rinsing with water if necessary obtain medical treatment.

⚠️ Warnings 76 words ▾

Warnings For external use only Do not use for injection for intraocular surgery internally If solution changes color or becomes cloudy. When using this product avoid contamination do not reuse. Once opened, discard. Ask a doctor if you have eye pain changes in vision redness or irritation of the eye after use an injury caused by alkali Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 5 words ▾

Active ingredient Purified water 99.1%

🧪 Inactive Ingredients 5 words ▾

Inactive ingredients Sterile Sodium Chloride

🎯 Purpose 3 words ▾

Purpose Emergency eyewash

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 72592-0003-60 · MV 72598-0095-20 · INNOVATIVE →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.