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Thera plus Antifungal Tolnaftate 10 mg/g Cream — NDC 80684-0040-01 package photo

Thera plus Antifungal Tolnaftate 10 mg/g Cream

by FOURSTAR GROUP USA, INC. · 1 TUBE in 1 BOX (80684-040-01) / 14 g in 1 TUBE
NDC 80684-0040-01
🏷️ FDA NDC (as labeled) 80684-040-01 billing pads the product segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 80684-040-01
Product NDC 80684-040
11-digit billing NDC 80684004001
RxCUI 103951
UNII 06KB629TKV
UPC 0049696866637
Application # M005
SPL Set ID c628dda8-7a6d-5f3a-e053-2995a90a35f8
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2022-01-30
Route TOPICAL
Dosage form CREAM
Substance TOLNAFTATE
Why two NDCs? The FDA registers this code as 80684-040-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 80684-0040-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Other antifungals for topical use class.

Drug family (ATC) Other antifungals for topical use
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerFOURSTAR GROUP USA, INC.
FDA applicationM005 (OTC MONOGRAPH DRUG)
Labeler code80684
First marketedJan 2022
Product typeHuman Otc Drug
Portfolio147 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📖 What it is MedlinePlus · NLM

Tolnaftate stops the growth of fungi that cause skin infections, including athlete's foot, jock itch, and ringworm. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • It depends on what you're treating. For athlete's foot and ringworm, plan on using it daily for about 4 weeks. For jock itch, 2 weeks is the usual course. Some products mention you...
  • How long does it take for tolnaftate to work?
  • Tolnaftate is not effective for treating infections on the scalp or on the nails themselves — most products say so right on the label. Some liquid and patch products are designed t...
  • Stop applying the product and let your doctor know. A little initial sensitivity can happen, but worsening irritation is a sign that you should get it checked out. Don't push throu...
📖 Read our full Tolnaftate guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 936JST6JCN
    Cetyl alcohol is a waxy, fatty substance derived from plant or animal sources. It acts as an emulsifier and thickener in medicines, helping blend oil and water components and giving products a smooth, creamy texture.
  • UNII 14255EXE39
    Ethylparaben is a preservative, a chemical that stops bacteria and mold from growing in the medicine. It keeps the product safe and effective throughout its shelf life.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 230OU9XXE4
    A waxy substance made from glycerin and stearic acid that acts as an emulsifier to blend oily and watery ingredients together. It also helps thicken and stabilize the medicine's texture.
  • UNII T5L8T28FGP
    Mineral oil is a clear, odorless liquid derived from crude oil. It acts as a lubricant and emollient in medications, helping pills slide smoothly during manufacturing and aiding moisture retention in topical products.
  • UNII 4T6H12BN9U
    Petrolatum is a purified mineral oil-based jelly derived from petroleum. In medicines, it acts as an emollient, lubricant, and moisture barrier to soften skin, reduce friction, and help prevent water loss from formulations.
  • UNII 368GB5141J
    A detergent and foaming agent derived from coconut or palm oil. In medications, it helps break down and mix oil and water-based ingredients, aids in tablet disintegration, and improves how the drug dissolves and spreads in the mouth or digestive system.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

8 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescetyl alcohol, ethylparaben, glycerol, glyceryl monostearate, mineral oil, petrolatum, purified water, sodium lauryl sulfate

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
CR-371059 Tolnaftate 1% Cream 1 g/100g 00536-1315-43 Rugby 1 g $0.091 — Availability likely —
Tolnaftate Antifungal 10 mg/g 24385-0032-03 Amerisource 1 tube $0.122 — Availability likely —
Tolnaftate Cream 1% ANTIFUNGAL 1 g/100g 70000-0084-01 CARDINAL 1 tube $0.122 — Availability likely —
sunmark antifungal 10 mg/g 49348-0155-29 Strategic 1 tube $0.152 — Availability likely —
Tolnaftate Antifungal 1 g/100g 51672-2020-01 Sun 1 tube $0.152 — Availability likely —
Tolnaftate Antifungal 1 g/100g 70677-1001-01 STRATEGIC 1 tube $0.152 — Availability likely —
Odor-Eaters Athletes Foot 1 g/100g 10157-3100-01 Blistex 1 tube — — FDA listed —
Mentholatum Heel Revival Cream 10 mg/g 10742-0020-01 The 1 tube — — FDA listed —
Tinactin 10 mg/g 11523-0934-02 Bayer 1 tube — — FDA listed —
Tinactin 10 mg/g 11523-1190-01 Bayer 1 tube — — FDA listed —
Tolnaftate 10 mg/g 11527-0051-40 Sheffield 1 tube — — FDA listed —
Signature Care Antifungal Cream Tolnaftate 1% 10 mg/g 21130-0887-14 BETTER 1 tube — — FDA listed —
meijer antifungal 10 mg/g 41250-0499-01 Meijer 1 tube — — FDA listed —
AVON HeXashield Athletes Foot Cream 10 mg/g 43136-0104-01 Tai 1 tube — — FDA listed —
CLARUS Antifungal 1 g/100g 44577-0001-01 Clinical 45 g — — FDA listed —
CLARUS Antifungal 10 mg/g 44577-0470-00 Clinical 1 tube — — FDA listed —
equate Athletes Foot 10 mg/g 49035-0499-03 Wal-Mart 1 tube — — FDA listed —
sunmark antifungal 10 mg/g 50090-3358-00 A-S 1 tube — — FDA listed —
CR-371059 Tolnaftate 1% 1 g/100g 50090-6147-00 A-S 14.8 g — — FDA listed —
CAREALL Tolnaftate 10 mg/g 51824-0001-01 New 28 g — — FDA listed —
Family Wellness Athletes Foot Tolnaftate 1 Cream 10 mg/g 55319-0991-00 Family 1 tube — — FDA listed —
Athletes Foot Antifungal .01 mg/10g 55910-0341-24 Dollar 1 tube — — FDA listed —
Pedikleer 1 g/100g 57237-0354-15 Rising 1 tube — — FDA listed —
Hongo Killer 10 mg/g 58593-0286-01 Efficient 1 tube — — FDA listed —
Family Care Antifungal 10 mg/g 65923-0021-28 United 1 tube — — FDA listed —
Winco Antifungal 10 mg/g 67091-0051-28 WinCo 1 tube — — FDA listed —
Winco Foods Tolnaftate 10 mg/g 67091-0276-28 Winco 1 tube — — FDA listed —
Natureplex Tolnaftate Antifungal 10 mg/g 67234-0032-01 Natureplex, 1 tube — — FDA listed —
Tolnaftate Cream 1% 10 mg/g 68016-0152-01 Pharmacy 1 tube — — FDA listed —
Tolnaftate 10 mg/g 68071-4245-05 NuCare 14.18 g — — FDA listed —
Skinheal Antifungal 1 g/100g 69070-0305-01 Zhejiang 1 tube — — FDA listed —
Tolnaftate Cream 1% ANTIFUNGAL 1 g/100g 69396-0016-05 Trifecta 1 tube — — FDA listed —
Tolnaftate Cream 1% ANTIFUNGAL 1 g/100g 69396-0042-05 Trifecta 1 tube — — FDA listed —
Tolnaftate 1 g/100g 69396-0130-01 Trifecta 1 tube — — FDA listed —
Canespies 1 g/100g 69729-0610-05 OPMX 1 tube — — FDA listed —
CVS Health Athletes Foot 10 mg/g 69842-0336-14 CVS 1 tube — — FDA listed —
Athletes Foot 10 mg/g 70084-0510-01 Quantum, 1 tube — — FDA listed —
Aftate Athlete Foot Cream 1 g/100g 70356-0001-01 Sabel 28 g — — FDA listed —
TheraCare Antifungal Cream 10 mg/g 71101-0017-01 Veridian 1 tube — — FDA listed —
Funginix Af 1 g/100g 71229-0103-11 The 28 g — — FDA listed —
Funginix Jock Itch Treatment 1 g/100g 71229-0104-11 The 28 g — — FDA listed —
TriTolnacide C 1 g/100mL 73352-0561-10 Trifluent 1 bottle — — FDA listed —
Dr.Scholl s Odor X Athlete s Foot 10 mg/g 73469-0618-01 Scholl's 1 bottle — — FDA listed —
Thera plus Antifungal Tolnaftate 10 mg/gthis 80684-0040-01 FOURSTAR 1 tube — — FDA listed —
Derman antifungal cream 10 mg/g 81929-0004-01 Taisho 1 tube — — FDA listed —
Up and Up Antifungal 10 mg/g 82442-0020-28 Target 1 tube — — FDA listed —
Antifungal 1 g/100g 83324-0049-01 Chain 1 tube — — FDA listed —
Sylvirene Fungal Nail Renewal 1 g/100mL 85248-0068-01 Jiangxi 30 ml — — FDA listed —
Tagrid Athletes Foot Treament 10 mg/g 85384-0008-01 TAGRID 100 g — — FDA listed —
Initial Drug Listing - Hermon Athletes Foot 1% Tolnaftate Cream .6 g/60g 85398-0017-01 Beautivity 60 g — — FDA listed —
Antifungal Medicated Bar 10 mg/g 85424-0001-01 RoyceDerm 232 g — — FDA listed —
Tagrid Antifungal 10 mg/g 85384-0013-01 TAGRID 113.4 g — — FDA listed —
Tagrid Antifungal 10 mg/g 85384-0010-01 TAGRID 142 g — — FDA listed —
DG Health Athletes Foot 10 mg/g 55910-0027-28 Dolgencorp, 1 tube — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2022
On the market since
Jan 2022
📍
2026
Currently FDA-listed
4 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
80684-0040-01 You're viewing this 1 TUBE in 1 BOX (80684-040-01) / 14 g in 1 TUBE 2022-01-30 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 80684-040-01, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 80684-0040-01, written without dashes as 80684004001. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 80684-0040-01, the first segment (80684) is the labeler code FDA assigned to FOURSTAR GROUP USA, INC.; the middle segment (0040) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by FOURSTAR GROUP USA, INC.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
FOURSTAR GROUP USA, INC. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 35 words ▾

Uses proven clinically effective in the treatment of most athlete's foot (tinea pedis), and ringworm (tinea corporis) helps prevent most athlete's foot with daily use for effective relief of itching , burning , and cracking

⏱️ Dosage and Administration 86 words ▾

Directions wash affected area and dry thoroughly apply a thin layer over affected area twice daily (morning and night) supervise children in the use of this product for athlete’s foot: pay special attention to spaces between the toes, wear well-ftting, ventilated shoes and change shoes and socks at least once daily use daily for 4 weeks ; if condition persists longer, ask a doctor. to prevent athlete’s foot, apply once or twice daily (morning and/or night). this product is not effective on the scalp or nails.

⚠️ Warnings 67 words ▾

Warnings For external use only. Do not use on children under 2 years of age except under the advice and supervision of a doctor. When using this product avoid contact with the eyes. Stop use and ask a doctor if irritation occurs there is no improvement within 4 weeks. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center immediately.

🧪 Active Ingredient 6 words ▾

Active ingredient Tolnaftate 1% Purpose Anti-Fungal

🧪 Inactive Ingredients 16 words ▾

Inactive ingredients cetyl alcohol, ethylparaben, glycerol, glyceryl monostearate, mineral oil, petrolatum, purified water, sodium lauryl sulfate

🎯 Purpose 2 words ▾

Purpose Anti-Fungal

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 80684-0039-01 · FOURSTAR 80684-0060-02 · Fourstar →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.