Guaifenesin 100 mg/5mL Liquid, 473 mL — NDC 81033-102-16 (Billing 81033-0102-16)
This is a package of 473 mL of Guaifenesin 100 mg/5mL Liquid from KESIN PHARMA CORPORATION, marketed since Apr 2025 and currently FDA-listed; retail pharmacies pay about $0.0110 per mL (NADAC). It is the main listing for this product, which comes in 3 package sizes.
NDC database record
One package, one record: these facts belong to NDC 81033-102-16 alone.
- Record
- FDA NDC Directory package listing · Human OTC drug
- Code segments
- 81033 labeler · 102 product · 16 package
- Package marketed since
- Apr 1, 2025
- Sample package
- No — commercial package
- Listing certified through
- Dec 31, 2026
- Billing quantity
- 473 mL per package
- Barcode (UPC-A, from the NDC)
- 3 8103310216 0
- Medicaid fills, this package
- 578 prescriptions in the last four reported quarters
- FDA record last changed
- Oct 8, 2026
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification
- GSN (GCN sequence number): 022210
- GCN: 02512
- GPI-14 (Medi-Span): 43200010000910
- HICL (First Databank): 000271
- AHFS class code: 48:16.00.00
- RxCUI (RxNorm): 310604
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 8, 2026
- FDA label on DailyMed · label index refreshed Oct 8, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 1, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 8, 2026
RxNorm drug class
This medicine belongs to the Expectorant class.
Where does this data come from?
- RxClass (NLM) · catalog refreshed Oct 1, 2026
Clinical
Guaifenesin is used to relieve chest congestion. Guaifenesin may help control symptoms but does not treat the cause of symptoms or speed recovery. Guaifenesin is in a class of medications called expectorants. It works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.
Read the full MedlinePlus article ↗- Guaifenesin doesn't suppress your cough — it actually makes it work better. It loosens and thins the mucus in your chest so your cough can move it out of your airways more effectiv...
- What exactly does guaifenesin do — does it actually stop my cough?
- No — extended-release tablets like 12 Hour Mucus Relief and 365 Whole Foods Market Guaifenesin must be swallowed whole. Crushing, chewing, or breaking them releases the medicine al...
- Can I crush or split the extended-release tablet to make it easier to swallow?
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Guaifenesin — tap one for details:
Where does this data come from?
- MedlinePlus (NLM) · refreshed Oct 8, 2026
- FDA label on DailyMed · label index refreshed Oct 8, 2026
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.011 | $5.20 / 473 ml |
| Medicaid paysCMS SDUD · 12 mo | $0.0287 | $13.58 / 473 ml |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
- CMS NADAC weekly file · file of Oct 7, 2026
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · through Q1 2026
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Per unit | Per pack | Marketing start | Marketing end | Status |
|---|---|---|---|---|---|---|
| 81033-0102-51 81033-102-51 | 50 CUP, UNIT-DOSE in 1 CARTON / 5 mL in 1 CUP, UNIT-DOSE | — | — | 2023-11-20 | — | Active |
| 81033-0102-52 81033-102-52 | 50 CUP, UNIT-DOSE in 1 CARTON / 10 mL in 1 CUP, UNIT-DOSE | — | — | 2023-11-20 | — | Active |
| 81033-0102-16 You're viewing this Main listing | 473 mL in 1 BOTTLE | $0.0110 / mL | $5.22 | 2025-04-01 | — | Active |
In Medicaid, this is the most-dispensed pack of this product — about 45% of fills over the last four reported quarters. See all packs ↓
Pack size FAQ
What quantity is in this package?
What NDC number is used to bill for this package of Guaifenesin 100 mg/5mL Liquid?
Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.
Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Chest Congestion Relief 100 mg/5mL 00536-1314-85 | RUGBY | 473 ml | $0.011 | — | Availability likely | — |
| Guaifenesin 100 mg/5mL 58657-0508-16 | Method | 473 ml | $0.011 | — | Availability likely | — |
| Guaifenesin 100 mg/5mLthis 81033-0102-16 | KESIN | 473 ml | $0.011 | — | Availability likely | — |
| Guaifenesin 100 mg/5mL 83720-0503-16 | Oncor | 473 ml | $0.011 | — | Availability likely | — |
| Guaifenesin 100 mg/5mL 58657-0509-16 | Method | 473 ml | $0.013 | — | FDA listed | +21% |
| Good Neighbor Adult Tussin Mucus and chest congestion 200 mg/10mL 46122-0785-29 | AMERISOURCE | 1 bottle | $0.023 | — | Availability likely | +108% |
| Tusnel EX 100 mg/5mL 54859-0507-04 | Llorens | 118 ml | $0.023 | — | Availability likely | +108% |
| Mucolyte 100 mg/5mL 57237-0359-12 | Rising | 118 ml | $0.023 | — | Availability likely | +108% |
| Tussin 200 mg/10mL 70677-1186-01 | Strategic | 1 bottle | $0.023 | — | Availability likely | +108% |
| Tussin Mucus and Chest Congestion Sugar Free 200 mg/10mL 82568-0012-04 | AARNA | 1 bottle | $0.023 | — | Availability likely | +108% |
| QCH Adult Tussin 541 200 mg/10mL 83324-0024-04 | Chain | 1 bottle | $0.023 | — | Availability likely | +108% |
| Mucinex Fast-Max Chest Congestion Honey and Berry Flavor 400 mg/20mL 63824-0537-66 | Reckitt | 180 ml | $0.061 | — | FDA listed | +450% |
| Guaifenesin 100 mg/5mL 00121-0744-04 | PAI | 118 ml | — | — | FDA listed | — |
| Guaifenesin 200 mg/10mL 00121-1488-00 | PAI | 10 cups | — | — | FDA listed | — |
| Guaifenesin 100 mg/5mL 00121-1744-00 | PAI | 10 cups | — | — | FDA listed | — |
| Guaifenesin 300 mg/15mL 00121-2232-00 | PAI | 10 cups | — | — | FDA listed | — |
| Walgreen Cherry 200 mg/10mL 00363-7043-08 | WALGREEN | 1 bottle | — | — | FDA listed | — |
| Childrens Chest Congestion Relief 100 mg/5mL 00363-7504-04 | WALGREENS | 1 bottle | — | — | FDA listed | — |
| Tusnel EX 100 mg/5mL 50090-6542-00 | A-S | 118 ml | — | — | FDA listed | — |
| CVS Adult Mucus plus Chest Congestion 200 mg/10mL 51316-0437-08 | CVS | 1 bottle | — | — | FDA listed | — |
| CVS Adult Mucus chest congestion 200 mg/10mL 51316-0743-08 | CVS | 1 bottle | — | — | FDA listed | — |
| Tussin 100 mg/5mL 53943-0507-26 | Discount | 237 ml | — | — | FDA listed | — |
| Childrens Chest Congestion Relief Grape 100 mg/5mL 53943-0511-24 | Discount | 118 ml | — | — | FDA listed | — |
| Llorens Care Tussin 100 mg/5mL 54859-0510-16 | Llorens | 473 ml | — | — | FDA listed | — |
| Guaifenesin 200 mg/10mL 55154-5780-05 | Cardinal | 5 cups | — | — | FDA listed | — |
| Guaifenesin 100 mg/5mL 55154-9450-05 | Cardinal | 5 cups | — | — | FDA listed | — |
| Geri-Tussin 200 mg/10mL 57896-0293-16 | Geri-Care | 473 ml | — | — | FDA listed | — |
| Geri-Tussin 100 mg/5mL 57896-0693-16 | Geri-Care | 473 ml | — | — | FDA listed | — |
| Cough Out 100 mg/5mL 58593-0255-04 | Efficient | 118 ml | — | — | Discontinued | — |
| Rompe Pecho SF 100 mg/5mL 58593-0265-04 | Efficient | 118 ml | — | — | Discontinued | — |
| Rompe Pecho EX 200 mg/10mL 58593-0829-04 | Efficient | 118 ml | — | — | FDA listed | — |
| Guaifenesin 100 mg/5mL 60687-0852-17 | American | 10 cups | — | — | FDA listed | — |
| Guaifenesin 200 mg/10mL 60687-0863-56 | American | 10 cups | — | — | FDA listed | — |
| Guaifenesin 300 mg/15mL 60687-0874-16 | American | 10 cups | — | — | FDA listed | — |
| Childrens Mucus Relief Chest Congestion 100 mg/5mL 63868-0770-04 | Chain | 1 bottle | — | — | FDA listed | — |
| SDA Laboratories Tussin 100 mg/5mL 66424-0563-16 | SDA | 473 ml | — | — | FDA listed | — |
| DRx Choice Fruit Punch 200 mg/10mL 68163-0743-04 | Raritan | 1 bottle | — | — | FDA listed | — |
| Adult Tussin 200 mg/10mL 69230-0332-23 | Camber | 1 bottle | — | — | FDA listed | — |
| Reliable-1 Tussin 100 mg/5mL 69618-0068-54 | RELIABLE | 118 ml | — | — | FDA listed | — |
| Akin 100 mg/5mL 69822-0200-02 | Southern | 118 ml | — | — | FDA listed | — |
| MAX Tussin Mucus and Chest Congestion Sugar Free 200 mg/10mL 71399-0024-04 | Akron | 1 bottle | — | — | FDA listed | — |
| MAX Tussin Mucus and Chest Congestion 200 mg/10mL 71399-0054-08 | Akron | 1 bottle | — | — | FDA listed | — |
| Guaifenesin STRAWBERRY-BANANA FLAVOR 100 mg/5mL 71800-0059-19 | Innovida | 119 ml | — | — | FDA listed | — |
| Guaifenesin 100 mg/5mL 72162-2278-02 | Bryant | 473 ml | — | — | FDA listed | — |
| Guaifed 200 mg/10mL 73564-0801-04 | Aldama | 118 ml | — | — | FDA listed | — |
| Tussin Expectorant 100 mg/5mL 76281-0507-24 | AptaPharma, | 118 ml | — | — | FDA listed | — |
| Meijer Adult Mucus Plus chest congestion 200 mg/10mL 79481-7430-08 | MEIJER | 1 bottle | — | — | FDA listed | — |
| Quality Choice Adult Tussin Expectorant 200 mg/10mL 83324-0332-04 | QUALITY | 1 bottle | — | — | FDA listed | — |
| Curewell Tussin 100 mg/5mL 85111-0693-16 | RMT | 473 ml | — | — | FDA listed | — |
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 8, 2026
- FDA Orange Book · refreshed Oct 3, 2026
- CMS NADAC weekly file · file of Oct 7, 2026
Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
- FDA Orange Book · refreshed Oct 3, 2026
What it looks like
Where does this data come from?
- FDA label on DailyMed · label index refreshed Oct 8, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
🧪 Avoiding an ingredient? See Guaifenesin inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII 3VRD35U26C
A natural extract from licorice root, ammonium glycyrrhizate is used as a flavoring agent and sweetener in medicines. It may also help soothe irritated tissues in the mouth or throat.
-
UNII 2968PHW8QP
A weak organic acid derived from citrus fruits or made through fermentation. It works as a buffer to control pH, a preservative to extend shelf life, and a flavoring agent in medications.
-
UNII A2I8C7HI9T
Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
-
UNII 86R1NVR0HW
A salt derived from citric acid and potassium. It acts as a buffer to regulate acidity in the medicine and may also help with disintegration or dissolution of the tablet.
-
UNII 6DC9Q167V3
Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
-
UNII Z8IX2SC1OH
Propylparaben is a chemical preservative used to prevent bacterial and fungal growth in medicines and personal care products. It helps extend shelf life and maintain product safety during storage.
-
UNII 506T60A25R
Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.
-
UNII 96K6UQ3ZD4
Sucralose is a synthetic sweetener made from sugar. It's added to medicines to improve taste without adding calories, helping make bitter or unpleasant-tasting drugs easier to take.
-
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
9 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.- FDA label on DailyMed · label index refreshed Oct 8, 2026
- FDA openFDA NDC Directory · synced Oct 8, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
Manufacturer & labeler
More NDCs from KESIN PHARMA CORPORATION labeler code 81033
- Hydroxyzine Hydrochloride 10 mg/5mL Solution NDC 81033-031-44
- Mupirocin 20 mg/g Ointment NDC 81033-032-50
- TOPIRAMATE 25 mg/mL Solution NDC 81033-035-14
- Mineral Oil 1000 mg/mL Solution NDC 81033-042-50
- LIKMEZ Metronidazole Oral 100 mg/mL Suspension NDC 81033-066-20
- Loperamide Hydrochloride 1 mg/7.5mL Solution NDC 81033-067-34
- Dextromethorphan HBr and Guaifenesin Oral Solution 100 mg/5mL; 10 mg/5mL Liquid NDC 81033-103-50
- Atovaquone 750 mg/5mL Suspension NDC 81033-104-22
- Atovaquone Oral Suspension 750 mg/5mL Suspension NDC 81033-105-22
- Senna Syrup 8.8 mg/5mL Syrup NDC 81033-120-50
- Gabapentin 250 mg/5mL Solution NDC 81033-123-16
- Gabapentin 50 mg/mL Solution NDC 81033-124-44
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 8, 2026
- Drugs@FDA
FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses Helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
⏱️ Dosage and Administration ▾
Directions Follow dosage below or use as directed by a physician. • Do not take more than 6 doses in any 24-hour period Age Dose Adults and children 12 years and over 10 to 20mL (2 to 4 teaspoonfuls) every 4 hours Children 6 years to under 12 years 5 to 10mL (1 to 2 teaspoonfuls) every 4 hours Children 2 to under 6 years of age 2.5 to 5mL (1/2 to 1 teaspoonful) every 4 hours Children under 2 years of age Consult a physician
⚠️ Warnings ▾
Warnings Ask a doctor before us if you have • cough that occurs with too much phlegm (mucus) • cough that lasts or is chronic such as occurs with smoking, asthma, chronic bronchitis, or emphysema Stop and ask a doctor if • cough lasts mor than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition. • you are hypersensitive to any of the ingredients If pregnant or breast-feeding, ask a health professional before use.
📦 How Supplied / Storage and Handling ▾
How Supplied: Guaifenesin Oral Solution is a clear, colorless solution with a grape flavor, free of visible foreign matter supplied in the following oral dosage forms: NDC 81033-102-05: 5mL unit dose cup NDC 81033-102-51: Case containing 100 unit dose cups of 5 mL packaged in 2 cartons of 50 unit dose cups each NDC 81033-102-10: 10mL unit dose cup NDC 81033-102-52: Case containing 100 unit dose cups of 10 mL packaged in 2 cartons of 50 unit dose cups each NDC 81033-102-15: 15 mL unit dose cup NDC 81033-102-53: Case containing 100 unit dose cups of 15 mL packaged in 2 cartons of 50 unit dose cups each
📦 Storage and Handling ▾
STORAGE Keep tightly closed. Store at controlled room temperature, 20°C to 25°C (68°F to 77°F). [See USP] Protect from light
🧪 Active Ingredient ▾
Description Each 5mL (1 teaspoonful) contains: Guaifenesin 100mg
🧪 Inactive Ingredients ▾
Inactive Ingredients Mixture of Guaifenesin with GRAS material additions including Citric Acid, Grape Flavor Methylparaben, Monoammonium Glycyrrhizate, Potassium Citrate, Propylene Glycol, Propylparaben, Purified Water, Sorbitol, Sucralose
🎯 Purpose ▾
Guaifenesin Solution 5mL Expectorant Sugar Free / Dye Free / Alcohol Free
📄 Keep Out of Reach of Children ▾
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Professional Note: Guaifenesin has been shown to produce a color interference with certain clinical laboratory determinations of 5-hydroxyindoleacetic acid (5-HIAA) and vanillylmandelic acid (VMA).
📄 Questions or Comments ▾
QUESTIONS OR COMMENTS QUESTIONS OR COMMENTS Call 1-833-537-4679 Packaged by: Kesin Pharma Oldsmar, FL 34677 Effective: 09/2024 Rev. 03 Kesin Pharma Logo
📄 Package Label / Principal Display Panel ▾
5 mL Unit Dose Cup Case Label NDC 81033-102-51 Guaifenesin Oral Solution, USP100 mg/5 mL Delivers 5 mL Case = 100 UD Cups (Do Not Break Case) Store at 68°F to 77°F (20°C to 25°C) QTY 1 Guaifenesin Oral Solution 5 mL Case Label
10 mL Unit Dose Cup Case Label NDC 81033-102-52 Guaifenesin Oral Solution, USP 200 mg/10 mL Delivers 10 mL Case = 100 UD Cups (Do Not Break Case) Store at 68°F to 77°F (20°C to 25°C) QTY 1 Guaifenesin Oral Solution 10 mL Case Label
15 mL Unit Dose Cup Case Label NDC 81033-102-53 Guaifenesin Oral Solution, USP 300 mg/15 mL Delivers 15 mL Case = 100 UD Cups (Do Not Break Case) QTY 1 Guaifenesin Oral Solution 15 mL Case Label