J0878
J0878 – Injection, daptomycin, 1 mg · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 55 NDCs crosswalked per 1 MG $0.029/unit ASP+6%
📋 J0878 summary
J0878 is a HCPCS Level II J-code used to bill daptomycin, 1 mg, billed per 1 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Brand names associated with J0878: Cubicin Rf*, Daptomycin
Code J0878
Billing unit 1 MG Payment limit $0.029/unit NDC-Crosswalk 55
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ0878
DescriptorInjection, daptomycin, 1 mg
Billing unit1 MG
Payment limit / unit$0.029
Est. ASP / unit$0.027 est.
Mapped NDCs55
Data periodQ3 2026
Last updated2026-08-20
💊 About Daptomycin DRUG GUIDE
Daptomycin injection is used to treat complicated skin and skin structure infections (cSSSI) caused by certain Gram-positive bacteria, including MRSA (methicillin-resistant Staphylococcus aureus).
It is also used to treat Staphylococcus aureus bloodstream infections (bacteremia), including right-sided infective endocarditis (a serious infection of the heart's right-side valves), in adults.
Several products — including Daptomycin in Sodium Chloride Injection, Dapzura RT, and others — extend these uses to pediatric patients aged 1 to 17 years for both cSSSI and S.
aureus bacteremia.Daptomycin is not used to treat pneumonia or left-sided infective endocarditis, and it is not recommended for infants younger than 1 year of age.
Clinical overview from our editorial drug guide for Daptomycin. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$0.029
Est. ASP / unit
$0.027 est.
Est. after 2% sequester
$0.028
HCPCS dosage
1 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, daptomycin, 1 mg
CoverageC — Carrier/MAC judgment
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment group—
Action codeP — Payment change
Effective date2024-01-01
Date added2005-01-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J0878 = 1 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J0878 LEAST EXPENSIVE FIRST
55 NDCs map to J0878. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($0.029/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 16729-0434-05 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Accord | 1 VIAL in 1 CARTON (16729-434-05) / 7 mL... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | CMS + PDAC |
| 25021-0179-15 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Sagent | 1 VIAL in 1 CARTON (25021-179-15) / 7 mL... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | CMS + PDAC |
| 25021-0179-66 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Sagent | 1 VIAL in 1 CARTON (25021-179-66) / 7 mL... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | CMS + PDAC |
| 43598-0476-11 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Dr. | 1 VIAL, SINGLE-DOSE in 1 CARTON (43598-476... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | CMS + PDAC |
| 71288-0017-15 | DAPTOMYCIN 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Meitheal | 1 VIAL, SINGLE-DOSE in 1 CARTON (71288-017... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | CMS + PDAC |
| 71288-0017-91 | DAPTOMYCIN 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Meitheal | 1 VIAL, SINGLE-DOSE in 1 CARTON (71288-017... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | CMS + PDAC |
| 71839-0108-01 | daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | BE | 1 VIAL in 1 CARTON (71839-108-01) / 7 mL... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | CMS + PDAC |
| 72603-0147-01 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | NorthStar | 1 VIAL, SINGLE-DOSE in 1 CARTON (72603-147... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | CMS + PDAC |
| 31722-0215-01 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Camber | 1 VIAL, SINGLE-DOSE in 1 CARTON (31722-215... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | PDAC |
| 00409-0120-01 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Hospira, | 1 VIAL, SINGLE-DOSE in 1 CARTON (0409-0120... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | PDAC |
| 72572-0100-01 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Civica, | 1 VIAL, SINGLE-USE in 1 CARTON (72572-100-... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | PDAC |
| 70594-0053-01 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Xellia | 1 VIAL, SINGLE-USE in 1 CARTON (70594-053-... | 350 mg/7mL | 350 | $10.15 | $13.418 | ● Active | PDAC |
| 42023-0295-10 | Daptomycin 500 mg/1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Par | 10 VIAL, SINGLE-DOSE in 1 CARTON (42023-29... | 500 mg/1 | 500 | $14.50 | $20.769 | ● Active | PDAC |
| 63323-0371-19 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Fresenius | 1 VIAL, SINGLE-DOSE in 1 CARTON (63323-371... | 500 mg/10mL | 500 | $14.50 | $20.769 | ● Active | PDAC |
| 63323-0371-10 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Fresenius | 1 VIAL, SINGLE-DOSE in 1 CARTON (63323-371... | 500 mg/10mL | 500 | $14.50 | $20.769 | ● Active | PDAC |
| 00409-0122-01 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Hospira, | 1 VIAL, SINGLE-DOSE in 1 CARTON (0409-0122... | 500 mg/10mL | 500 | $14.50 | $20.769 | ● Active | PDAC |
| 16714-0892-01 | Daptomycin 50 mg/mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | NorthStar | 1 VIAL, SINGLE-DOSE in 1 CARTON (16714-892... | 50 mg/mL | 500 | $14.50 | $21.846 | Obsolete | CMS + PDAC |
| 16729-0435-05 | DAPTOMYCIN 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Accord | 1 VIAL, SINGLE-DOSE in 1 CARTON (16729-435... | 500 mg/10mL | 500 | $14.50 | $21.846 | ● Active | CMS + PDAC |
| 00143-9444-01 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Hikma | 1 VIAL, SINGLE-DOSE in 1 CARTON (0143-9444... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 00143-9465-01 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Hikma | 1 VIAL, SINGLE-USE in 1 CARTON (0143-9465-... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 25021-0174-15 | daptomycin 50 mg/mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Sagent | 1 VIAL in 1 CARTON (25021-174-15) / 10 mL... | 50 mg/mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 25021-0174-16 | daptomycin 50 mg/mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Sagent | 10 VIAL in 1 CARTON (25021-174-16) / 10 m... | 50 mg/mL | 5,000 | $145.00 | $22.687 | ● Active | CMS + PDAC |
| 43598-0413-11 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Dr.Reddy's | 1 VIAL, SINGLE-DOSE in 1 CARTON (43598-413... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 55150-0344-01 | DAPTOMYCIN 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Eugia | 1 VIAL, SINGLE-DOSE in 1 CARTON (55150-344... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 60505-6229-04 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | APOTEX | 1 VIAL, SINGLE-USE in 1 CARTON (60505-6229... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 67457-0813-50 | daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Mylan | 1 VIAL, SINGLE-DOSE in 1 CARTON (67457-813... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 67457-0941-15 | daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Mylan | 1 VIAL, SINGLE-DOSE in 1 CARTON (67457-941... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 68001-0376-68 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | BluePoint | 1 VIAL, SINGLE-DOSE in 1 CARTON (68001-376... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 70377-0093-91 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Biocon | 1 VIAL, SINGLE-USE in 1 CARTON (70377-093-... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 70594-0034-01 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Xellia | 1 VIAL, SINGLE-USE in 1 CARTON (70594-034-... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 70594-0034-02 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Xellia | 1 VIAL, SINGLE-USE in 1 CARTON (70594-034-... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 71288-0016-15 | DAPTOMYCIN 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Meitheal | 1 VIAL, SINGLE-DOSE in 1 CARTON (71288-016... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 71288-0016-91 | DAPTOMYCIN 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Meitheal | 1 VIAL, SINGLE-DOSE in 1 CARTON (71288-016... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 71288-0016-95 | DAPTOMYCIN 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Meitheal | 1 VIAL, SINGLE-DOSE in 1 CARTON (71288-016... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 71839-0107-01 | daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | BE | 1 VIAL, SINGLE-DOSE in 1 CARTON (71839-107... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 72572-0102-01 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Civica, | 1 VIAL, SINGLE-USE in 1 CARTON (72572-102-... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 72603-0152-01 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | NorthStar | 1 VIAL, SINGLE-DOSE in 1 CARTON (72603-152... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | CMS + PDAC |
| 31722-0216-01 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Camber | 1 VIAL, SINGLE-DOSE in 1 CARTON (31722-216... | 500 mg/10mL | 500 | $14.50 | $22.687 | ● Active | PDAC |
| 00143-9378-01 | Daptomycin 500 mg/10mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Hikma | 1 VIAL, SINGLE-DOSE in 1 CARTON (0143-9378... | 500 mg/10mL | 500 | $14.50 | — | Obsolete | CMS + PDAC |
| 16729-0434-45 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Accord | 10 VIAL in 1 CARTON (16729-434-45) / 7 mL... | 350 mg/7mL | 3,500 | $101.50 | — | ● Active | CMS + PDAC |
| 25021-0179-16 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Sagent | 10 VIAL in 1 CARTON (25021-179-16) / 7 mL... | 350 mg/7mL | 3,500 | $101.50 | — | ● Active | CMS + PDAC |
| 25021-0179-67 | Daptomycin 350 mg/7mL INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | Sagent | 10 VIAL in 1 CARTON (25021-179-67) / 7 mL... | 350 mg/7mL | 3,500 | $101.50 | — | ● Active | CMS + PDAC |
| 31722-0102-10 | DAPTOMYCIN (SDV,PF,LYOPHILIZED) 500 MG | Unknown | — | — | 500 | $14.50 | — | — | PDAC |
| 71288-0018-10 | DAPTOMYCIN (SDV,PF,LATEX-FREE) 500 MG | Unknown | — | — | 500 | $14.50 | — | — | PDAC |
| 69097-0850-67 | DAPTOMYCIN (SDV,PF,LATEX-FREE) 350 MG | Unknown | — | — | 350 | $10.15 | — | — | PDAC |
| 68001-0467-41 | DAPTOMYCIN (SDV,PF,LATEX-FREE) 350 MG | Unknown | — | — | 350 | $10.15 | — | — | PDAC |
| 00409-5933-01 | DAPTOMYCIN (SDV,PF,LATEX-FREE) 350 MG | Unknown | — | — | 350 | $10.15 | — | — | PDAC |
| 00409-2757-01 | DAPTOMYCIN (SDV,PF,LATEX-FREE) 500 MG | Unknown | — | — | 500 | $14.50 | — | — | PDAC |
| 00781-3295-70 | DAPTOMYCIN (SDV,PF,LYOPHILIZED) 500 MG | Unknown | — | — | 500 | $14.50 | — | — | PDAC |
| 69097-0807-37 | DAPTOMYCIN (SDV,PF,LYOPHILIZED) 500 MG | Unknown | — | — | 500 | $14.50 | — | — | PDAC |
| 63323-0585-15 | DAPTOMYCIN (PF,LYOPHILIZED) 350 MG | Unknown | — | — | 350 | $10.15 | — | — | PDAC |
| 00409-0106-01 | DAPTOMYCIN (SDV,PF,LYOPHILIZED) 500 MG | Unknown | — | — | 500 | $14.50 | — | — | PDAC |
| 00703-0125-01 | DAPTOMYCIN (PF,LYOPHILIZED) 500 MG | Unknown | — | — | 500 | $14.50 | — | — | PDAC |
| 63323-0871-15 | DAPTOMYCIN (PF,LYOPHILIZED) 500 MG | Unknown | — | — | 500 | $14.50 | — | — | PDAC |
| 67919-0011-01 | CUBICIN (PF) 500 MG | Unknown | — | — | 500 | $14.50 | — | — | PDAC |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)
Period
Total Part B spend
$192.9K
Claims
9,691
Beneficiaries
843
Spend / beneficiary
$228.88
Spend / claim
$19.91
Trend by period
Where J0878 ranks among Part B drugs · 2026 (Q1) · neighbors ±5
Total spending — #531 of 824
#526
ORION, PER SQ CM** Q4276
$197.2K
#527
ARTACENT WOUND, PER... Q4169
$196.1K
#528
ENVERSE, PER SQ CM** Q4258
$195.1K
#529
FLEXHD** Q4128
$193.7K
#530
IPRATROPIUM BROMIDE J7644
$193.1K
#531
CUBICIN RF* J0878
$192.9K
#532
AMNIO TRI-CORE, PER... Q4295
$191.6K
#533
DOBUTAMINE HCL-D5W* J1250
$183.5K
#534
TROGARZO J1746
$183.1K
#535
AXOLOTL DUALGRAFT, P... Q4332
$182.5K
#536
FIBRYGA J7177
$178.7K
Total claims — #164 of 824
#159
RAPAMUNE* J7520
10,934
#160
GADOTERIDOL* A9579
10,762
#161
LIBTAYO J9119
10,576
#162
CAMPTOSAR* J9206
10,330
#163
ZARXIO Q5101
10,231
#164
CUBICIN RF* J0878
9,691
#165
TRIESENCE J3300
9,687
#166
CYCLOSPORINE MODIFIE... J7515
9,668
#167
FOCINVEZ J1434
9,640
#168
ARALAST NP* J0256
9,390
#169
RENFLEXIS Q5104
9,046
Top Medicare Part B drugs by the selected metric. Click any drug to open its J-code page. Source: CMS Medicare Quarterly Part B Spending by Drug.
Full breakdown by period (2)
| Period | Total spend | Beneficiaries | Claims | $/beneficiary | $/claim |
|---|---|---|---|---|---|
| 2026 (Q1) | $192.9K | 843 | 9,691 | $228.88 | $19.91 |
| 2025 (Q1-Q4) | $1.27M | 3,439 | 54,890 | $370.41 | $23.21 |
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.
📈 Medicare Part B claims detail CMS PSPS · 2024
Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$1.25M
Medicare paid
$964.5K
Submitted services
65,913,454
Denial rate
40.8%
Allowed / service
$0.03
Submitted charges
$78.23M
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.
🗺️ Where J0878 is utilized CMS · BY PROVIDER · 2024
Medicare Part B services for this code by the rendering provider's state — 27,807,315 services across 26 states & territories in 2024 (CMS reports include DC and U.S. territories). Switch to per 100k to compare states fairly regardless of population. Hover or tap a state for its top ZIP codes.
Hover or tap a state to see its numbers + top ZIP codes.
Per-capita = services ÷ 2023 state population × 100,000 (so high-population states aren't automatically "hotter"). Counts reflect the provider's location, not the patient's. Providers with fewer than 11 patients are hidden by CMS for privacy, so totals run low and per-100k can be noisy in small states — read this as relative geography, not exact counts. Source: CMS Medicare Physician & Other Practitioners — by Provider and Service, 2024.
📊 What bills under J0878
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
55 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J0878 billing FAQ
What is HCPCS code J0878?
J0878 is a HCPCS Level II J-code used to bill Injection, daptomycin, 1 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J0878?
One unit of J0878 represents 1 MG. Report the number of units equal to the dose administered divided by 1 MG.
How many units of J0878 should I bill?
Divide the dose administered by the code's unit size (1 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J0878?
The Medicare Part B payment limit is $0.029 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $0.028 per unit. Payment limits are revised quarterly.
Which NDCs bill under J0878?
55 NDCs currently map to J0878 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J0878 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.