J7515
J7515 – Cyclosporine, oral, 25 mg · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 18 NDCs crosswalked per 25 MG $0.552/unit ASP+6%
📋 J7515 summary
J7515 is a HCPCS Level II J-code used to bill Cyclosporine, oral, 25 mg, billed per 25 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Brand names associated with J7515: Cyclosporine Modified(J7515)*, Gengraf, Sandimmune
Code J7515
Billing unit 25 MG Payment limit $0.552/unit NDC-Crosswalk 18
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ7515
DescriptorCyclosporine, oral, 25 mg
Billing unit25 MG
Payment limit / unit$0.552
Est. ASP / unit$0.521 est.
Mapped NDCs18
Data periodQ3 2026
Last updated2026-08-20
💊 About Cyclosporine Injection DRUG GUIDE
Sandimmune injection, given with adrenal corticosteroids (steroid medicines), is used to help prevent the body from rejecting a transplanted kidney, liver, or heart.
It is also used to treat chronic rejection in patients who have already been treated with other immunosuppressive medicines.Sandimmune injection is reserved for patients who are unable to take Sandimmune capsules by mouth.
Because of the risk of a serious allergic reaction (anaphylaxis), the injection form is only used when the oral form is not an option.
Clinical overview from our editorial drug guide for Cyclosporine Injection. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$0.552
Est. ASP / unit
$0.521 est.
Est. after 2% sequester
$0.541
HCPCS dosage
25 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionCyclosporine, oral, 25 mg
CoverageC — Carrier/MAC judgment
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment group—
Action codeN — No maintenance this year
Effective date2000-01-01
Date added2000-01-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J7515 = 25 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J7515 LEAST EXPENSIVE FIRST
18 NDCs map to J7515. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($0.552/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 00093-9018-65 | Cyclosporine Modified 25 mg/1 CAPSULE, LIQUID FILLED | Teva | 30 BLISTER PACK in 1 CARTON (0093-9018-65)... | 25 mg/1 | 30 | $16.56 | $0.317 | ● Active | CMS + PDAC |
| 23155-0837-30 | CYCLOSPORINE 25 mg/1 CAPSULE, LIQUID FILLED | Heritage | 3 BLISTER PACK in 1 CARTON (23155-837-30)... | 25 mg/1 | 30 | $16.56 | $0.317 | ● Active | CMS + PDAC |
| 60505-4630-03 | CycloSPORINE, Modfied 25 mg/1 CAPSULE, LIQUID FILLED | Apotex | 30 BLISTER PACK in 1 CARTON (60505-4630-3)... | 25 mg/1 | 30 | $16.56 | $0.317 | ● Active | CMS + PDAC |
| 75907-0047-30 | Cyclosporine 25 mg/1 CAPSULE, LIQUID FILLED | Dr. | 30 BLISTER PACK in 1 BOX (75907-047-30) /... | 25 mg/1 | 1 | $0.55 | $0.318 | ● Active | PDAC |
| 23155-0838-30 | CYCLOSPORINE 50 mg/1 CAPSULE, LIQUID FILLED | Heritage | 6 BLISTER PACK in 1 CARTON (23155-838-30)... | 50 mg/1 | 60 | $33.12 | $0.779 | ● Active | CMS + PDAC |
| 60505-4631-03 | CycloSPORINE, Modfied 50 mg/1 CAPSULE, LIQUID FILLED | Apotex | 30 BLISTER PACK in 1 CARTON (60505-4631-3)... | 50 mg/1 | 60 | $33.12 | $0.779 | ● Active | CMS + PDAC |
| 00093-9019-65 | Cyclosporine Modified 50 mg/1 CAPSULE, LIQUID FILLED | Teva | 30 BLISTER PACK in 1 CARTON (0093-9019-65)... | 50 mg/1 | 2 | $1.10 | $0.779 | ● Active | PDAC |
| 00074-3108-32 | Gengraf Cyclosporine 25 mg/1 CAPSULE | AbbVie | 3 BLISTER PACK in 1 CARTON (0074-3108-32)... | 25 mg/1 | 30 | $16.56 | $1.865 | ● Active | CMS + PDAC |
| 60505-0133-00 | Cyclosporine 25 mg/1 CAPSULE, GELATIN COATED | Apotex | 30 CAPSULE, GELATIN COATED in 1 BOTTLE (60... | 25 mg/1 | 30 | $16.56 | $2.578 | ● Active | CMS + PDAC |
| 68084-0879-25 | Cyclosporine 25 mg/1 CAPSULE, GELATIN COATED | American | 30 BLISTER PACK in 1 BOX, UNIT-DOSE (68084... | 25 mg/1 | 30 | $16.56 | $2.578 | ● Active | CMS ASP |
| 00078-0246-15 | Neoral cyclosporine 25 mg/1 CAPSULE, LIQUID FILLED | Novartis | 30 BLISTER PACK in 1 CARTON (0078-0246-15)... | 25 mg/1 | 30 | $16.56 | $2.946 | ● Active | CMS + PDAC |
| 00078-0240-15 | Sandimmune cyclosporine 25 mg/1 CAPSULE, LIQUID FILLED | Novartis | 30 BLISTER PACK in 1 PACKAGE (0078-0240-15... | 25 mg/1 | 30 | $16.56 | — | ● Active | CMS + PDAC |
| 00078-0240-61 | SANDIMMUNE (INNER PACK, SOFTGEL) 25 MG | Unknown | — | — | 1 | $0.55 | — | — | PDAC |
| 51862-0458-47 | CYCLOSPORINE (USP,MODIFIED) 25 MG | Unknown | — | — | 1 | $0.55 | — | — | PDAC |
| 00093-5741-65 | CYCLOSPORINE, MODIFIED (USP,SOFTGEL) 50 MG | Unknown | — | — | 2 | $1.10 | — | — | PDAC |
| 00093-5740-65 | CYCLOSPORINE, MODIFIED (SOFT GELATIN) 25 MG | Unknown | — | — | 1 | $0.55 | — | — | PDAC |
| 00093-5740-19 | CYCLOSPORINE, MODIFIED (INNERPACK,SOFT GELATIN) 25 MG | Unknown | — | — | 1 | $0.55 | — | — | PDAC |
| 00185-0932-30 | CYCLOSPORINE (SOFTGEL) 25 MG | Unknown | — | — | 1 | $0.55 | — | — | PDAC |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)
Period
Total Part B spend
$811.9K
Claims
9,668
Beneficiaries
4,222
Spend / beneficiary
$192.30
Spend / claim
$83.98
Trend by period
Where J7515 ranks among Part B drugs · 2026 (Q1) · neighbors ±5
Total spending — #400 of 824
#395
TEMOZOLOMIDE J8700
$858.1K
#396
INTEGRA BMWD** Q4104
$855.9K
#397
REZZAYO J0349
$844.7K
#398
NIVESTYM Q5110
$835.2K
#399
FEIBA J7198
$830K
#400
CYCLOSPORINE MODIFIE... J7515
$811.9K
#401
COMPLETE SL PER SQ C... Q4270
$803.1K
#402
CYCLOPHOSPHAMIDE(J90... J9073
$799.5K
#403
XIPERE J3299
$787.6K
#404
RECLAST* J3489
$779.5K
#405
AFFINITY1 SQUARE CM*... Q4159
$769.7K
Total claims — #166 of 824
#161
LIBTAYO J9119
10,576
#162
CAMPTOSAR* J9206
10,330
#163
ZARXIO Q5101
10,231
#164
CUBICIN RF* J0878
9,691
#165
TRIESENCE J3300
9,687
#166
CYCLOSPORINE MODIFIE... J7515
9,668
#167
FOCINVEZ J1434
9,640
#168
ARALAST NP* J0256
9,390
#169
RENFLEXIS Q5104
9,046
#170
CYCLOPHOSPHAMIDE(J90... J9075
8,806
#171
AMINOPHYLLINE J0280
8,705
Top Medicare Part B drugs by the selected metric. Click any drug to open its J-code page. Source: CMS Medicare Quarterly Part B Spending by Drug.
Full breakdown by period (2)
| Period | Total spend | Beneficiaries | Claims | $/beneficiary | $/claim |
|---|---|---|---|---|---|
| 2026 (Q1) | $811.9K | 4,222 | 9,668 | $192.30 | $83.98 |
| 2025 (Q1-Q4) | $5.23M | 5,481 | 45,682 | $954.26 | $114.49 |
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.
📈 Medicare Part B claims detail CMS PSPS · 2024
Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$5.36M
Medicare paid
$4.01M
Submitted services
7,250,720
Denial rate
4.2%
Allowed / service
$0.77
Submitted charges
$14.1M
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.
📊 What bills under J7515
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
18 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J7515 billing FAQ
What is HCPCS code J7515?
J7515 is a HCPCS Level II J-code used to bill Cyclosporine, oral, 25 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J7515?
One unit of J7515 represents 25 MG. Report the number of units equal to the dose administered divided by 25 MG.
How many units of J7515 should I bill?
Divide the dose administered by the code's unit size (25 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J7515?
The Medicare Part B payment limit is $0.552 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $0.541 per unit. Payment limits are revised quarterly.
Which NDCs bill under J7515?
18 NDCs currently map to J7515 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J7515 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.