J2305
J2305 – Injection, nitroglycerin, 5 mg · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 6 NDCs crosswalked per 5 MG $1.557/unit ASP+6%
📋 J2305 summary
J2305 is a HCPCS Level II J-code used to bill nitroglycerin, 5 mg, billed per 5 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Brand names associated with J2305: Nitroglycerin In D5W*, Nitroglycerin In Dextrose, Nitroglycerin
Code J2305
Billing unit 5 MG Payment limit $1.557/unit NDC-Crosswalk 6
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ2305
DescriptorInjection, nitroglycerin, 5 mg
Billing unit5 MG
Payment limit / unit$1.557
Est. ASP / unit$1.469 est.
Mapped NDCs6
Data periodQ3 2026
Last updated2026-08-20
💊 About Nitroglycerin DRUG GUIDE
Nitroglycerin is used for several different conditions depending on the form.
Fast-acting forms — sublingual tablets, lingual sprays — treat or prevent acute angina attacks (sudden chest pain from coronary artery disease).
Nitro-Time extended-release capsules and transdermal skin patches (Nitro-Dur and others) are used to prevent angina; they work too slowly to stop an attack already in progress.Rectiv rectal ointment (0.4%) is specifically indicated for moderate to severe pain from chronic anal fissure.
Intravenous nitroglycerin (Nitroglycerin Injection and Nitroglycerin in Dextrose) is used in hospital settings to treat peri-operative high blood pressure, control heart failure during a heart attack, manage angina that hasn't responded to other treatments, and produce controlled low blood pressure during surgery.
Clinical overview from our editorial drug guide for Nitroglycerin. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$1.557
Est. ASP / unit
$1.469 est.
Est. after 2% sequester
$1.526
HCPCS dosage
5 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, nitroglycerin, 5 mg
CoverageC — Carrier/MAC judgment
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment groupYY
Action codeP — Payment change
Effective date2024-01-01
Date added2023-07-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J2305 = 5 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J2305 WITH EST. MEDICARE PAY
6 NDCs map to J2305. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($1.557/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 00338-1047-02 | Nitroglycerin In Dextrose 10 mg/100mL INJECTION | Baxter | 12 BOTTLE, GLASS in 1 BOX (0338-1047-02)... | 10 mg/100mL | 60 | $93.42 | — | ● Active | CMS + PDAC |
| 00338-1049-02 | Nitroglycerin In Dextrose 20 mg/100mL INJECTION | Baxter | 12 BOTTLE, GLASS in 1 BOX (0338-1049-02)... | 20 mg/100mL | 120 | $186.84 | — | ● Active | CMS + PDAC |
| 00338-1051-02 | Nitroglycerin In Dextrose 40 mg/100mL INJECTION | Baxter | 12 BOTTLE, GLASS in 1 BOX (0338-1051-02)... | 40 mg/100mL | 240 | $373.68 | — | ● Active | CMS + PDAC |
| 00404-9928-10 | Nitroglycerin 5 mg/mL INJECTION, SOLUTION | Henry | 1 VIAL in 1 BAG (0404-9928-10) / 10 mL in... | 5 mg/mL | 10 | $15.57 | — | ● Active | CMS ASP |
| 00517-4810-25 | Nitroglycerin 5 mg/mL INJECTION, SOLUTION | American | 25 VIAL, SINGLE-DOSE in 1 TRAY (0517-4810-... | 5 mg/mL | 250 | $389.25 | — | ● Active | CMS + PDAC |
| 51662-1386-01 | Nitroglycerin | HF | — | — | 10 | $15.57 | — | — | CMS ASP |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)
Period
Total Part B spend
$1.5K
Claims
164
Beneficiaries
156
Spend / beneficiary
$9.48
Spend / claim
$9.02
Trend by period
Where J2305 ranks among Part B drugs · 2026 (Q1) · neighbors ±5
Total spending — #754 of 824
#749
ACETAMINOPHEN(J0136) J0136
$1.7K
#750
BICILLIN C-R J0558
$1.7K
#751
RECOMBIVAX HB 90743
$1.7K
#752
ADRENALIN(J0169) J0169
$1.6K
#753
NALBUPHINE HCL J2300
$1.5K
#754
NITROGLYCERIN IN D5W... J2305
$1.5K
#755
AMPHADASE J3470
$1.4K
#756
TIGAN J3250
$1.4K
#757
AMPICILLIN-SULBACTAM... J0295
$1.3K
#758
HYDRALAZINE HCL J0360
$1.3K
#759
DOXY 100* J1271
$1.3K
Total claims — #574 of 824
#569
QALSODY J1304
172
#570
CEFOXITIN SODIUM* J0694
170
#571
IBANDRONATE SODIUM J1740
170
#572
AMNIPLY, PER SQ CM** Q4249
169
#573
YEZTUGO(J0752) J0752
165
#574
NITROGLYCERIN IN D5W... J2305
164
#575
PRIALT J2278
163
#576
AXOLOTL DUALGRAFT, P... Q4332
161
#577
BRIXADI(J0578) J0578
160
#578
GASTROGRAFIN* Q9963
159
#579
ONPATTRO J0222
157
Top Medicare Part B drugs by the selected metric. Click any drug to open its J-code page. Source: CMS Medicare Quarterly Part B Spending by Drug.
Full breakdown by period (2)
| Period | Total spend | Beneficiaries | Claims | $/beneficiary | $/claim |
|---|---|---|---|---|---|
| 2026 (Q1) | $1.5K | 156 | 164 | $9.48 | $9.02 |
| 2025 (Q1-Q4) | $3.2K | 431 | 486 | $7.52 | $6.67 |
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.
📈 Medicare Part B claims detail CMS PSPS · 2024
Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$1.2K
Medicare paid
$1K
Submitted services
1,110
Denial rate
19.9%
Allowed / service
$1.35
Submitted charges
$13.2K
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.
🗺️ Where J2305 is utilized CMS · BY PROVIDER · 2024
Medicare Part B services for this code by the rendering provider's state — 365 services across 6 states & territories in 2024 (CMS reports include DC and U.S. territories). Switch to per 100k to compare states fairly regardless of population. Hover or tap a state for its top ZIP codes.
Hover or tap a state to see its numbers + top ZIP codes.
Per-capita = services ÷ 2023 state population × 100,000 (so high-population states aren't automatically "hotter"). Counts reflect the provider's location, not the patient's. Providers with fewer than 11 patients are hidden by CMS for privacy, so totals run low and per-100k can be noisy in small states — read this as relative geography, not exact counts. Source: CMS Medicare Physician & Other Practitioners — by Provider and Service, 2024.
📊 What bills under J2305
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
6 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Not available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J2305 billing FAQ
What is HCPCS code J2305?
J2305 is a HCPCS Level II J-code used to bill Injection, nitroglycerin, 5 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J2305?
One unit of J2305 represents 5 MG. Report the number of units equal to the dose administered divided by 5 MG.
How many units of J2305 should I bill?
Divide the dose administered by the code's unit size (5 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J2305?
The Medicare Part B payment limit is $1.557 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $1.526 per unit. Payment limits are revised quarterly.
Which NDCs bill under J2305?
6 NDCs currently map to J2305 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J2305 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.