J8501
J8501 – Aprepitant, oral, 5 mg · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 39 NDCs crosswalked per 5 MG $3.069/unit ASP+6%
📋 J8501 summary
J8501 is a HCPCS Level II J-code used to bill Aprepitant, oral, 5 mg, billed per 5 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Brand names associated with J8501: Emend
Code J8501
Billing unit 5 MG Payment limit $3.069/unit NDC-Crosswalk 39
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ8501
DescriptorAprepitant, oral, 5 mg
Billing unit5 MG
Payment limit / unit$3.069
Est. ASP / unit$2.895 est.
Mapped NDCs39
Data periodQ3 2026
Last updated2026-08-20
💊 About Aprepitant DRUG GUIDE
Aprepitant is used to prevent nausea and vomiting — not to treat it once it has started.
It is always used alongside other anti-nausea medicines, not on its own.EMEND capsules (oral) are approved for adults and children 12 and older to prevent nausea from highly or moderately emetogenic (nausea-causing) chemotherapy.
EMEND for oral suspension extends that same use down to children as young as 6 months.
CINVANTI (IV injection) is approved for adults only, for chemotherapy-related nausea.
Clinical overview from our editorial drug guide for Aprepitant. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$3.069
Est. ASP / unit
$2.895 est.
Est. after 2% sequester
$3.008
HCPCS dosage
5 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionAprepitant, oral, 5 mg
CoverageD — Special coverage instructions apply
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment group—
Action codeN — No maintenance this year
Effective date2019-01-01
Date added2005-01-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J8501 = 5 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J8501 LEAST EXPENSIVE FIRST
39 NDCs map to J8501. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($3.069/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 00781-2321-06 | Aprepitant 40 mg/1 CAPSULE | Sandoz | 1 BLISTER PACK in 1 CARTON (0781-2321-06)... | 40 mg/1 | 8 | $24.55 | $45.388 | ● Active | CMS ASP |
| 00781-2321-51 | Aprepitant 40 mg/1 CAPSULE | Sandoz | 5 BLISTER PACK in 1 CARTON (0781-2321-51)... | 40 mg/1 | 40 | $122.76 | $45.388 | ● Active | CMS ASP |
| 13668-0591-81 | APREPITANT 40 mg/1 CAPSULE | Torrent | 1 BLISTER PACK in 1 CARTON (13668-591-81)... | 40 mg/1 | 8 | $24.55 | $45.388 | ● Active | CMS + PDAC |
| 13668-0591-82 | APREPITANT 40 mg/1 CAPSULE | Torrent | 5 BLISTER PACK in 1 CARTON (13668-591-82)... | 40 mg/1 | 40 | $122.76 | $45.388 | ● Active | CMS + PDAC |
| 68001-0666-01 | Aprepitant 40 mg/1 CAPSULE | BluePoint | 1 BLISTER PACK in 1 CARTON (68001-666-01)... | 40 mg/1 | 8 | $24.55 | $45.388 | ● Active | CMS + PDAC |
| 68001-0666-17 | Aprepitant 40 mg/1 CAPSULE | BluePoint | 5 BLISTER PACK in 1 CARTON (68001-666-17)... | 40 mg/1 | 40 | $122.76 | $45.388 | ● Active | CMS + PDAC |
| 68462-0583-40 | Aprepitant 40 mg/1 CAPSULE | Glenmark | 1 BLISTER PACK in 1 CARTON (68462-583-40)... | 40 mg/1 | 8 | $24.55 | $45.388 | ● Active | CMS ASP |
| 68462-0583-85 | Aprepitant 40 mg/1 CAPSULE | Glenmark | 5 BLISTER PACK in 1 CARTON (68462-583-85)... | 40 mg/1 | 40 | $122.76 | $45.388 | ● Active | CMS + PDAC |
| 00781-2322-46 | Aprepitant 80 mg/1 CAPSULE | Sandoz | 2 CAPSULE in 1 DOSE PACK (0781-2322-46) | 80 mg/1 | 32 | $98.21 | $76.852 | ● Active | CMS ASP |
| 00781-2322-68 | Aprepitant 80 mg/1 CAPSULE | Sandoz | 1 BLISTER PACK in 1 CARTON (0781-2322-68)... | 80 mg/1 | 96 | $294.62 | $76.852 | ● Active | CMS ASP |
| 13668-0592-84 | APREPITANT 80 mg/1 CAPSULE | Torrent | 2 BLISTER PACK in 1 CARTON (13668-592-84)... | 80 mg/1 | 32 | $98.21 | $76.852 | ● Active | CMS + PDAC |
| 13668-0592-86 | APREPITANT 80 mg/1 CAPSULE | Torrent | 3 BLISTER PACK in 1 CARTON (13668-592-86)... | 80 mg/1 | 96 | $294.62 | $76.852 | ● Active | CMS + PDAC |
| 68001-0667-01 | Aprepitant 80 mg/1 CAPSULE | BluePoint | 2 CAPSULE in 1 DOSE PACK (68001-667-01) | 80 mg/1 | 32 | $98.21 | $76.852 | ● Active | CMS + PDAC |
| 68001-0667-19 | Aprepitant 80 mg/1 CAPSULE | BluePoint | 1 BLISTER PACK in 1 CARTON (68001-667-19)... | 80 mg/1 | 96 | $294.62 | $76.852 | ● Active | CMS + PDAC |
| 68462-0584-58 | Aprepitant 80 mg/1 CAPSULE | Glenmark | 2 CAPSULE in 1 DOSE PACK (68462-584-58) | 80 mg/1 | 32 | $98.21 | $76.852 | ● Active | CMS + PDAC |
| 68462-0584-76 | Aprepitant 80 mg/1 CAPSULE | Glenmark | 1 BLISTER PACK in 1 CARTON (68462-584-76)... | 80 mg/1 | 96 | $294.62 | $76.852 | ● Active | CMS + PDAC |
| 00781-4063-36 | Aprepitant KIT | Sandoz | 1 KIT in 1 DOSE PACK (0781-4063-36) * 1... | — | 57 | $174.93 | $87.266 | ● Active | CMS ASP |
| 13668-0594-87 | APREPITANT KIT | Torrent | 1 KIT in 1 DOSE PACK (13668-594-87) * 2... | — | 57 | $174.93 | $87.266 | ● Active | CMS + PDAC |
| 68001-0669-15 | Aprepitant KIT | BluePoint | 1 KIT in 1 DOSE PACK (68001-669-15) * 2... | — | 57 | $174.93 | $87.266 | ● Active | CMS + PDAC |
| 68462-0112-33 | Aprepitant KIT | Glenmark | 1 KIT in 1 DOSE PACK (68462-112-33) * 2... | — | 57 | $174.93 | $87.266 | ● Active | CMS ASP |
| 00781-2323-68 | Aprepitant 125 mg/1 CAPSULE | Sandoz | 1 BLISTER PACK in 1 CARTON (0781-2323-68)... | 125 mg/1 | 150 | $460.35 | $115.114 | ● Active | CMS ASP |
| 13668-0593-86 | APREPITANT 125 mg/1 CAPSULE | Torrent | 6 BLISTER PACK in 1 CARTON (13668-593-86)... | 125 mg/1 | 150 | $460.35 | $115.114 | ● Active | CMS + PDAC |
| 68001-0668-19 | Aprepitant 125 mg/1 CAPSULE | BluePoint | 1 BLISTER PACK in 1 CARTON (68001-668-19)... | 125 mg/1 | 150 | $460.35 | $115.114 | ● Active | CMS + PDAC |
| 68462-0585-76 | Aprepitant 125 mg/1 CAPSULE | Glenmark | 1 BLISTER PACK in 1 CARTON (68462-585-76)... | 125 mg/1 | 150 | $460.35 | $115.114 | ● Active | CMS + PDAC |
| 00006-0461-02 | EMEND aprepitant 80 mg/1 CAPSULE | Merck | 2 CAPSULE in 1 DOSE PACK (0006-0461-02) | 80 mg/1 | 32 | $98.21 | $208.983 | ● Active | CMS + PDAC |
| 00006-3066-03 | EMEND aprepitant 125 mg/1 POWDER, FOR SUSPENSION | Merck | 1 POUCH in 1 CARTON (0006-3066-03) / 1 PO... | 125 mg/1 | 25 | $76.73 | $327.384 | ● Active | CMS ASP |
| 00006-3862-03 | EMEND aprepitant KIT | Merck | 1 KIT in 1 DOSE PACK (0006-3862-03) * 1... | — | 57 | $174.93 | — | ● Active | CMS + PDAC |
| 51407-0704-03 | APREPITANT KIT | Golden | 1 KIT in 1 DOSE PACK (51407-704-03) * 2... | — | 41 | $125.83 | — | ● Active | PDAC |
| 51407-0703-06 | APREPITANT 125 mg/1 CAPSULE | Golden | 6 BLISTER PACK in 1 CARTON (51407-703-06)... | 125 mg/1 | 25 | $76.73 | — | ● Active | PDAC |
| 51407-0702-06 | APREPITANT 80 mg/1 CAPSULE | Golden | 3 BLISTER PACK in 1 CARTON (51407-702-06)... | 80 mg/1 | 16 | $49.10 | — | ● Active | PDAC |
| 51407-0702-02 | APREPITANT 80 mg/1 CAPSULE | Golden | 2 BLISTER PACK in 1 CARTON (51407-702-02)... | 80 mg/1 | 16 | $49.10 | — | ● Active | PDAC |
| 51407-0701-05 | APREPITANT 40 mg/1 CAPSULE | Golden | 5 BLISTER PACK in 1 CARTON (51407-701-05)... | 40 mg/1 | 8 | $24.55 | — | ● Active | PDAC |
| 51407-0701-01 | APREPITANT 40 mg/1 CAPSULE | Golden | 1 BLISTER PACK in 1 CARTON (51407-701-01)... | 40 mg/1 | 8 | $24.55 | — | ● Active | PDAC |
| 52959-0748-01 | EMEND 40 MG | Unknown | — | — | 8 | $24.55 | — | — | PDAC |
| 00006-3862-13 | EMEND aprepitant KIT | Merck | 1 KIT in 1 DOSE PACK (0006-3862-13) * 1... | — | 57 | $174.93 | — | ● Active | PDAC |
| 00006-0464-10 | EMEND 40 MG | Unknown | — | — | 8 | $24.55 | — | — | PDAC |
| 00006-0464-05 | EMEND 40 MG | Unknown | — | — | 8 | $24.55 | — | — | PDAC |
| 00006-0462-06 | EMEND 125 MG | Unknown | — | — | 25 | $76.73 | — | — | PDAC |
| 00006-0461-06 | EMEND 80 MG | Unknown | — | — | 16 | $49.10 | — | — | PDAC |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
📈 Medicare Part B claims detail CMS PSPS · 2024
Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$371.60
Medicare paid
$291.35
Submitted services
10,809
Denial rate
98.8%
Allowed / service
$2.90
Submitted charges
$80.3K
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.
📊 What bills under J8501
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
39 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
No reportable utilization
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J8501 billing FAQ
What is HCPCS code J8501?
J8501 is a HCPCS Level II J-code used to bill Aprepitant, oral, 5 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J8501?
One unit of J8501 represents 5 MG. Report the number of units equal to the dose administered divided by 5 MG.
How many units of J8501 should I bill?
Divide the dose administered by the code's unit size (5 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J8501?
The Medicare Part B payment limit is $3.069 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $3.008 per unit. Payment limits are revised quarterly.
Which NDCs bill under J8501?
39 NDCs currently map to J8501 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J8501 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.