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Tretinoin 0.5 MG/ML Topical Cream — RxCUI 106303

RxNorm drug concept · Semantic clinical drug
RxCUI 106303 Semantic clinical drug · SCD ● Current RxNorm concept 30 FDA products 52 package NDCs Snapshot Jul 14, 2026

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI106303
Official nameTretinoin 0.5 MG/ML Topical Cream
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known astretinoin 0.05 % Topical Cream
FDA products mapped30
Package NDCs mapped52
Reported Medicaid activity (SDUD)965,511 prescriptions · 50 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Tretinoin: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Honestly, it won't erase wrinkles — and the label is pretty direct about that. What it's approved to do is help reduce the appearance of fine wrinkles as part of a full routine tha...
  • Will tretinoin actually get rid of my wrinkles?
  • Redness, peeling, and irritation in the first couple of weeks are very common and usually mean your skin is adjusting — not that something is wrong. If it's tolerable, try hanging...
  • My skin is really red and peeling after the first week — should I stop?
📖 Read our full Tretinoin guide →

🕸️ Concept Web — How Tretinoin 0.5 MG/ML Topical Cream Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Tretinoin 0.5 MG/ML Topical Cream RxCUI 106303

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Tretinoin 10753
  2. Brand names 2

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Retin-A 153101
    • Tretin X 645646
  3. Dose forms 8

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Tretinoin Topical Cream 377828
    • Tretinoin Topical Product 1158220
    • Tretinoin Topical Cream [Retin-A] 362106
    • Tretinoin Topical Cream [Tretin X] 645668
    • Retin-A Topical Product 1182535
    • Tretin X Topical Product 1179676
    • Topical Cream 316982
    • Topical Product 1151122
  4. Clinical & branded drugs 5

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Tretinoin 0.5 MG/ML 328693
    • Tretinoin 0.5 MG/ML Topical Cream [Retin-A] 208330
    • Tretinoin 0.5 MG/ML Topical Cream [Tretin X] 656882
    • Tretinoin 0.5 MG/ML [Retin-A] 569035
    • Tretinoin 0.5 MG/ML [Tretin X] 656881

Showing up to 8 concepts per family — 16 of 16 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Tretinoin 0.5 MG/ML SCDC · 328693
  • Tretinoin Topical Cream SCDF · 377828
  • Tretinoin Topical Product SCDG · 1158220

Brand-Name Concepts

  • Tretinoin 0.5 MG/ML Topical Cream [Retin-A] SBD · 208330
  • Tretinoin 0.5 MG/ML Topical Cream [Tretin X] SBD · 656882
  • Tretinoin 0.5 MG/ML [Retin-A] SBDC · 569035
  • Tretinoin 0.5 MG/ML [Tretin X] SBDC · 656881
  • Tretinoin Topical Cream [Retin-A] SBDF · 362106
  • Tretinoin Topical Cream [Tretin X] SBDF · 645668
  • Retin-A Topical Product SBDG · 1182535
  • Tretin X Topical Product SBDG · 1179676
  • Retin-A BN · 153101
  • Tretin X BN · 645646

📦 FDA Products & Package NDCs

30 products · 52 package NDCs
52 package NDCs map to RxCUI 106303 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00187-5160-20 1 TUBE in 1 CARTON (0187-5160-20) / 20 g in 1 TUBE Retin-A Bausch Health US, LLC 1988-10-30
00187-5160-45 1 TUBE in 1 CARTON (0187-5160-45) / 45 g in 1 TUBE Retin-A Bausch Health US, LLC 1988-10-30
00187-5162-20 1 TUBE in 1 CARTON (0187-5162-20) / 20 g in 1 TUBE Retin-A Bausch Health US, LLC 1974-07-30
00187-5162-45 1 TUBE in 1 CARTON (0187-5162-45) / 45 g in 1 TUBE Retin-A Bausch Health US, LLC 1974-07-30
00187-5164-20 1 TUBE in 1 CARTON (0187-5164-20) / 20 g in 1 TUBE Retin-A Bausch Health US, LLC 1973-04-30
00187-5164-45 1 TUBE in 1 CARTON (0187-5164-45) / 45 g in 1 TUBE Retin-A Bausch Health US, LLC 1973-04-30
00187-5170-15 1 TUBE in 1 CARTON (0187-5170-15) / 15 g in 1 TUBE Retin-A Bausch Health US, LLC 1975-07-30
00187-5170-45 1 TUBE in 1 CARTON (0187-5170-45) / 45 g in 1 TUBE Retin-A Bausch Health US, LLC 1975-07-30
00187-5172-15 1 TUBE in 1 CARTON (0187-5172-15) / 15 g in 1 TUBE Retin-A Bausch Health US, LLC 1979-07-30
00187-5172-45 1 TUBE in 1 CARTON (0187-5172-45) / 45 g in 1 TUBE Retin-A Bausch Health US, LLC 1979-07-30
00378-8082-20 1 TUBE in 1 CARTON (0378-8082-20) / 20 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2019-04-29
00378-8082-45 1 TUBE in 1 CARTON (0378-8082-45) / 45 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2019-04-03
00378-8083-20 1 TUBE in 1 CARTON (0378-8083-20) / 20 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2019-07-12
00378-8083-45 1 TUBE in 1 CARTON (0378-8083-45) / 45 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2018-12-17
00378-8084-20 1 TUBE in 1 CARTON (0378-8084-20) / 20 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2019-07-25
00378-8084-45 1 TUBE in 1 CARTON (0378-8084-45) / 45 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2019-02-27
00378-8085-15 1 TUBE in 1 CARTON (0378-8085-15) / 15 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2019-08-12
00378-8085-45 1 TUBE in 1 CARTON (0378-8085-45) / 45 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2019-08-12
00378-8086-15 1 TUBE in 1 CARTON (0378-8086-15) / 15 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2019-07-12
00378-8086-45 1 TUBE in 1 CARTON (0378-8086-45) / 45 g in 1 TUBE Tretinoin Mylan Pharmaceuticals Inc. 2019-07-25
00574-2201-20 1 TUBE in 1 CARTON (0574-2201-20) / 20 g in 1 TUBE TRETINOIN Padagis US LLC 2017-03-30
00574-2201-45 1 TUBE in 1 CARTON (0574-2201-45) / 45 g in 1 TUBE TRETINOIN Padagis US LLC 2017-04-17
00574-2205-20 1 TUBE in 1 CARTON (0574-2205-20) / 20 g in 1 TUBE TRETINOIN Padagis US LLC 2017-05-05
00574-2205-45 1 TUBE in 1 CARTON (0574-2205-45) / 45 g in 1 TUBE TRETINOIN Padagis US LLC 2017-04-26
00574-2225-20 1 TUBE in 1 CARTON (0574-2225-20) / 20 g in 1 TUBE TRETINOIN Padagis US LLC 2017-06-15
00574-2225-45 1 TUBE in 1 CARTON (0574-2225-45) / 45 g in 1 TUBE TRETINOIN Padagis US LLC 2017-06-15
00574-2301-15 1 TUBE in 1 CARTON (0574-2301-15) / 15 g in 1 TUBE TRETINOIN Padagis US LLC 2017-07-28
00574-2301-45 1 TUBE in 1 CARTON (0574-2301-45) / 45 g in 1 TUBE TRETINOIN Padagis US LLC 2017-03-30
00574-2325-15 1 TUBE in 1 CARTON (0574-2325-15) / 15 g in 1 TUBE TRETINOIN Padagis US LLC 2017-03-07
00574-2325-45 1 TUBE in 1 CARTON (0574-2325-45) / 45 g in 1 TUBE TRETINOIN Padagis US LLC 2017-12-12
16714-0249-01 1 TUBE in 1 CARTON (16714-249-01) / 20 g in 1 TUBE Tretinoin NORTHSTAR RX LLC 2022-02-25
16714-0249-02 1 TUBE in 1 CARTON (16714-249-02) / 45 g in 1 TUBE Tretinoin NORTHSTAR RX LLC 2022-02-25
21922-0077-06 1 TUBE in 1 CARTON (21922-077-06) / 45 g in 1 TUBE Tretinoin Encube Ethicals, Inc. 2026-02-13
21922-0077-25 1 TUBE in 1 CARTON (21922-077-25) / 20 g in 1 TUBE Tretinoin Encube Ethicals, Inc. 2026-02-13
21922-0078-06 1 TUBE in 1 CARTON (21922-078-06) / 45 g in 1 TUBE Tretinoin Encube Ethicals, Inc. 2026-03-26
21922-0078-25 1 TUBE in 1 CARTON (21922-078-25) / 20 g in 1 TUBE Tretinoin Encube Ethicals, Inc. 2026-03-26
21922-0079-06 1 TUBE in 1 CARTON (21922-079-06) / 45 g in 1 TUBE Tretinoin Encube Ethicals, Inc. 2025-07-11
21922-0079-25 1 TUBE in 1 CARTON (21922-079-25) / 20 g in 1 TUBE Tretinoin Encube Ethicals, Inc. 2025-07-11
46708-0808-00 1 TUBE in 1 CARTON (46708-808-00) / 45 g in 1 TUBE Tretinoin Alembic Pharmaceuticals Limited 2026-06-11
46708-0808-20 1 TUBE in 1 CARTON (46708-808-20) / 20 g in 1 TUBE Tretinoin Alembic Pharmaceuticals Limited 2026-06-11
50090-3058-00 1 TUBE in 1 CARTON (50090-3058-0) / 45 g in 1 TUBE TRETINOIN A-S Medication Solutions 2017-06-15
50090-3128-00 1 TUBE in 1 CARTON (50090-3128-0) / 20 g in 1 TUBE TRETINOIN A-S Medication Solutions 2017-08-29
50090-6819-00 1 TUBE in 1 CARTON (50090-6819-0) / 45 g in 1 TUBE Tretinoin A-S Medication Solutions 2023-11-14
51672-1394-00 1 TUBE in 1 CARTON (51672-1394-0) / 20 g in 1 TUBE Tretinoin Sun Pharmaceutical Industries, Inc. 2019-01-25
51672-1394-09 1 TUBE in 1 CARTON (51672-1394-9) / 45 g in 1 TUBE Tretinoin Sun Pharmaceutical Industries, Inc. 2019-01-25
62032-0412-20 1 TUBE in 1 CARTON (62032-412-20) / 20 g in 1 TUBE Tretinoin Cream Obagi Cosmeceuticals LLC 1974-07-19
62032-0414-20 1 TUBE in 1 CARTON (62032-414-20) / 20 g in 1 TUBE Tretinoin Cream Obagi Cosmeceuticals LLC 1988-09-16
62032-0417-20 1 TUBE in 1 CARTON (62032-417-20) / 20 g in 1 TUBE Tretinoin Cream Obagi Cosmeceuticals LLC 1973-01-26
62332-0808-20 1 TUBE in 1 CARTON (62332-808-20) / 20 g in 1 TUBE Tretinoin Alembic Pharmaceuticals Inc. 2026-06-11
62332-0808-45 1 TUBE in 1 CARTON (62332-808-45) / 45 g in 1 TUBE Tretinoin Alembic Pharmaceuticals Inc. 2026-06-11
Observed labelers: Bausch Health US, LLC (10) · Mylan Pharmaceuticals Inc. (10) · Padagis US LLC (10) · Encube Ethicals, Inc. (6) · A-S Medication Solutions (3) · Obagi Cosmeceuticals LLC (3) · +6 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.