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Acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 100 MG / phenylep... — RxCUI 1098435

RxNorm drug concept · Semantic clinical drug
RxCUI 1098435 Semantic clinical drug · SCD ● Current RxNorm concept 24 FDA products 35 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1098435
Official nameAcetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 100 MG / phenylephrine hydrochloride 5 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 325 MG / Dextromethorphan Hydrobromide 10 MG / Guaifenesin 100 MG / Phenylephrine Hydrochloride 5 MG Oral Tablet; acetaminophen 325 MG / dextromethorphan HBr 10 MG / guaiFENesin 100 MG / phenylephrine HCl 5 MG Oral Tablet
FDA products mapped24
Package NDCs mapped35
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It depends on the product. The injection raises low blood pressure during anesthesia and, for some products, septic shock. Eye drops dilate the pupil, nasal products relieve conges...
  • Be careful. Over-the-counter phenylephrine should not be used with a prescription MAOI or within 2 weeks of stopping one. If you aren't sure whether your medicine is an MAOI, ask m...
  • With the injection, the most common are nausea, vomiting and headache. Call for help right away if you have chest pain, a very slow heartbeat, or pain or skin changes around the IV...
  • Stop and talk to a doctor if you get nervousness, dizziness or sleeplessness. Also stop if symptoms last more than 7 days or come with a fever. Don't use more than the label recomm...
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 325 MG / dextromethorphan hydrobro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 100 MG / phenylephrine hydrochloride 5 MG Oral Tablet RxCUI 1098435

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 7

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Dextromethorphan 3289
    • Guaifenesin 5032
    • Phenylephrine 8163
    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine 689776
    • Dextromethorphan hydrobromide 102490
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Oral Tablet 376003
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Tablet 2648597
    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Oral Product 1155905
    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Pill 1155906
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product 2662312
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Pill 2659957
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 325 MG 315263
    • Dextromethorphan hydrobromide 10 MG 1014455
    • Guaifenesin 100 MG 317640
    • Phenylephrine hydrochloride 5 MG 1020198
  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

    • {1 (acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 100 MG / phenylephrine hydrochloride 5 MG Oral Tablet) / 1 (acetaminophen 325 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 5 MG Oral Tablet) } Pack 2634562

Showing up to 8 concepts per family — 20 of 21 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 325 MG SCDC · 315263
  • Dextromethorphan hydrobromide 10 MG SCDC · 1014455
  • Guaifenesin 100 MG SCDC · 317640
  • Phenylephrine hydrochloride 5 MG SCDC · 1020198
  • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Oral Tablet SCDF · 376003
  • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Tablet SCDFP · 2648597
  • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Oral Product SCDG · 1155905
  • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Pill SCDG · 1155906
  • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product SCDGP · 2662312
  • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Pill SCDGP · 2659957

📦 FDA Products & Package NDCs

24 products · 35 package NDCs
35 package NDCs map to RxCUI 1098435 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00924-0142-01 50 PACKET in 1 BOX (0924-0142-01) / 2 TABLET, FILM COATED i... Physicians Care Non-Drowsy Cold and Cough Acme United 2023-01-19
11822-5462-09 2 BLISTER PACK in 1 CARTON (11822-5462-9) / 10 TABLET, FILM... Head Congestion and Flu Severe Relief Rite Aid Corporation 2021-05-05
27854-0350-01 2 BLISTER PACK in 1 CARTON (27854-350-01) / 12 TABLET, FILM... Sedalmex XL Flu Belmora LLC 2022-03-24
36800-0474-02 2 BLISTER PACK in 1 CARTON (36800-474-02) / 12 TABLET, COAT... Head Congestion plus Flu Severe PE TOPCO ASSOCIATES LLC 2021-04-30
37808-0574-02 2 BLISTER PACK in 1 CARTON (37808-574-02) / 12 TABLET, COAT... Head Congestion plus Flu Severe HEB 2023-04-14
41163-0713-02 2 BLISTER PACK in 1 CARTON (41163-713-02) / 12 TABLET, COAT... Head Congestion plus Flu Severe United Natural Foods, Inc. dba UNFI 2022-08-19
41250-0574-02 2 BLISTER PACK in 1 CARTON (41250-574-02) / 12 TABLET, COAT... head congestion plus flu severe PE MEIJER DISTRIBUTION INC 2022-09-23
47682-0047-47 100 PACKET in 1 BOX (47682-047-47) / 2 TABLET, FILM COATED... Multi-Symptom Cold Relief Unifirst First Aid Corporation 2022-09-26
47682-0047-80 40 PACKET in 1 BOX (47682-047-80) / 2 TABLET, FILM COATED i... Multi-Symptom Cold Relief Unifirst First Aid Corporation 2022-09-26
47682-0047-99 2 TABLET, FILM COATED in 1 PACKET (47682-047-99) Multi-Symptom Cold Relief Unifirst First Aid Corporation 2022-09-26
47682-0435-36 75 PACKET in 1 BOX (47682-435-36) / 2 TABLET, FILM COATED i... Medique Decorel Forte Unifirst First Aid Corporation 2022-12-12
47682-0435-80 40 PACKET in 1 BOX (47682-435-80) / 2 TABLET, FILM COATED i... Medique Decorel Forte Unifirst First Aid Corporation 2022-09-26
47682-0435-99 2 TABLET, FILM COATED in 1 PACKET (47682-435-99) Medique Decorel Forte Unifirst First Aid Corporation 2022-09-26
47682-0735-33 50 PACKET in 1 BOX (47682-735-33) / 2 TABLET, FILM COATED i... Medique at Home Decorel Forte Unifirst First Aid Corporation 2022-09-26
47682-0735-99 2 TABLET, FILM COATED in 1 PACKET (47682-735-99) Medique at Home Decorel Forte Unifirst First Aid Corporation 2022-09-26
47682-0835-36 75 PACKET in 1 BOX (47682-835-36) / 2 TABLET, FILM COATED i... Medi-First Cough Cold Unifirst First Aid Corporation 2022-12-12
47682-0835-80 40 PACKET in 1 BOX (47682-835-80) / 2 TABLET, FILM COATED i... Medi-First Cough Cold Unifirst First Aid Corporation 2022-09-26
47682-0835-99 2 TABLET, FILM COATED in 1 PACKET (47682-835-99) Medi-First Cough Cold Unifirst First Aid Corporation 2022-09-26
47682-0836-36 75 PACKET in 1 BOX (47682-836-36) / 2 TABLET, FILM COATED i... Medi-First Plus Cough Cold Unifirst First Aid Corporation 2022-12-12
47682-0836-80 40 PACKET in 1 BOX (47682-836-80) / 2 TABLET, FILM COATED i... Medi-First Plus Cough Cold Unifirst First Aid Corporation 2022-09-26
50332-0141-03 20 PACKET in 1 BAG (50332-0141-3) / 2 TABLET, FILM COATED i... CETAFEN COUGH and COLD HART Health 2023-01-09
50332-0141-04 40 PACKET in 1 BOX (50332-0141-4) / 2 TABLET, FILM COATED i... CETAFEN COUGH and COLD HART Health 2023-01-09
50332-0141-07 100 PACKET in 1 BOX (50332-0141-7) / 2 TABLET, FILM COATED... CETAFEN COUGH and COLD HART Health 2023-01-09
50580-0450-01 2 BLISTER PACK in 1 CARTON (50580-450-01) / 12 TABLET, FILM... SUDAFED PE Head Congestion Plus Flu Severe Kenvue Brands LLC 2019-06-17
50804-0274-02 2 BLISTER PACK in 1 CARTON (50804-274-02) / 12 TABLET, COAT... Head Congestion Flu Severe PE GOODSENSE 2022-08-03
51316-0546-08 2 BLISTER PACK in 1 CARTON (51316-546-08) / 12 TABLET, FILM... Sinus PE Head Congestion and Flu Severe CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED 2021-09-25
53943-0274-02 2 BLISTER PACK in 1 CARTON (53943-274-02) / 12 TABLET, COAT... Head Congestion plus Flu Severe PE DISCOUNT DRUG MART 2022-08-01
63868-0102-24 2 BLISTER PACK in 1 CARTON (63868-102-24) / 12 TABLET, COAT... Head Congestion Flu Severe PE CHAIN DRUG MARKETING ASSOCIATION INC 2022-08-03
63941-0274-02 2 BLISTER PACK in 1 CARTON (63941-274-02) / 12 TABLET, COAT... Head Congestion plus Flu Severe PE VALU MERCHANDISERS COMPANY 2023-04-14
72036-0274-02 2 BLISTER PACK in 1 CARTON (72036-274-02) / 12 TABLET, COAT... Head Congestion plus Flu Severe PE HARRIS TEETER 2022-07-08
72476-0174-02 2 BLISTER PACK in 1 CARTON (72476-174-02) / 12 TABLET, COAT... HEAD CONGESTION PLUS FLU SEVERE PE RETAIL BUSINESS SERVICES , LLC. 2022-10-25
73408-0835-80 40 PACKET in 1 BOX (73408-835-80) / 2 TABLET, FILM COATED i... Thompson Cough and Cold Multi-Symptom Relief Thompson 2022-09-26
84269-2556-01 50 PACKET in 1 BOX (84269-2556-1) / 2 TABLET, FILM COATED i... Cold Terminator Cold Relief Wildman Business Group 2024-07-01
84269-2556-02 75 PACKET in 1 BOX (84269-2556-2) / 2 TABLET, FILM COATED i... Cold Terminator Cold Relief Wildman Business Group 2024-07-01
85766-0174-01 50 PACKET in 1 BOX (85766-174-01) / 2 TABLET, FILM COATED i... Medique at Home Decorel Forte Sportpharm LLC 2026-02-27
Observed labelers: Unifirst First Aid Corporation (13) · HART Health (3) · Wildman Business Group (2) · Acme United (1) · Belmora LLC (1) · CHAIN DRUG MARKETING ASSOCIATION INC (1) · +14 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.