Home › NDC Lookup › RxCUI directory › RxCUI 1110988

Acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG / phenylep... — RxCUI 1110988

RxNorm drug concept · Semantic clinical drug
RxCUI 1110988 Semantic clinical drug · SCD ● Current RxNorm concept 138 FDA products 160 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1110988
Official nameAcetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG / phenylephrine hydrochloride 5 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG / phenylephrine hydrochloride 5 MG Oral Tablet; acetaminophen 325 MG / dextromethorphan HBr 10 MG / guaiFENesin 200 MG / phenylephrine HCl 5 MG Oral Tablet
FDA products mapped138
Package NDCs mapped160
Reported Medicaid activity (SDUD)119 prescriptions · 2 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It depends on the product. The injection raises low blood pressure during anesthesia and, for some products, septic shock. Eye drops dilate the pupil, nasal products relieve conges...
  • Be careful. Over-the-counter phenylephrine should not be used with a prescription MAOI or within 2 weeks of stopping one. If you aren't sure whether your medicine is an MAOI, ask m...
  • With the injection, the most common are nausea, vomiting and headache. Call for help right away if you have chest pain, a very slow heartbeat, or pain or skin changes around the IV...
  • Stop and talk to a doctor if you get nervousness, dizziness or sleeplessness. Also stop if symptoms last more than 7 days or come with a fever. Don't use more than the label recomm...
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 325 MG / dextromethorphan hydrobro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG / phenylephrine hydrochloride 5 MG Oral Tablet RxCUI 1110988

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 7

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Dextromethorphan 3289
    • Guaifenesin 5032
    • Phenylephrine 8163
    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine 689776
    • Dextromethorphan hydrobromide 102490
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Oral Tablet 376003
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Tablet 2648597
    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Oral Product 1155905
    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Pill 1155906
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product 2662312
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Pill 2659957
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 325 MG 315263
    • Dextromethorphan hydrobromide 10 MG 1014455
    • Guaifenesin 200 MG 317384
    • Phenylephrine hydrochloride 5 MG 1020198
  4. Packs 4

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 23 of 24 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

138 products · 160 package NDCs
160 package NDCs map to RxCUI 1110988 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00067-8145-01 2 BLISTER PACK in 1 CARTON (0067-8145-01) / 10 TABLET, COAT... Theraflu ExpressMax Severe Cold and Flu Caplets Haleon US Holdings LLC 2017-07-17
00113-4500-53 6 BLISTER PACK in 1 CARTON (0113-4500-53) / 2 TABLET, FILM... good sense severe day time cold and flu L. Perrigo Company 2019-12-02
00113-4500-62 12 BLISTER PACK in 1 CARTON (0113-4500-62) / 2 TABLET, FILM... good sense severe day time cold and flu L. Perrigo Company 2019-12-02
00363-0640-08 2 BLISTER PACK in 1 CARTON (0363-0640-08) / 12 TABLET, FILM... Cold and Flu Severe Walgreen Company 2014-02-27
00363-6171-09 2 BLISTER PACK in 1 CARTON (0363-6171-09) / 10 TABLET, FILM... Sinus Pressure, Pain and Cough Walgreen Company 2022-04-14
00363-6406-08 1 KIT in 1 PACKAGE, COMBINATION (0363-6406-08) * 8 TABLET,... Cold and Flu Daytime, Nighttime, Maximum Strength Walgreen Company 2015-08-01
00363-6406-22 1 KIT in 1 PACKAGE, COMBINATION (0363-6406-22) * 8 TABLET,... Cold and Flu Daytime, Nighttime, Maximum Strength Walgreen Company 2015-08-01
00363-9617-64 4 BLISTER PACK in 1 CARTON (0363-9617-64) / 1 KIT in 1 BLIS... Mucus DM Fast Max Day Cold and Flu and Night Cold and Flu WALGREENS 2024-12-23
11673-0343-64 4 BLISTER PACK in 1 CARTON (11673-343-64) / 1 KIT in 1 BLIS... Day Cold and Flu and Night Severe Cold and Flu TARGET CORPORATION 2024-05-01
11673-0347-02 2 BLISTER PACK in 1 CARTON (11673-347-02) / 10 TABLET, COAT... DAY COLD AND FLU TARGET CORPORATION 2025-04-01
11673-0961-09 2 BLISTER PACK in 1 CARTON (11673-961-09) / 10 TABLET, FILM... sinus pressure and pain and cough Target Corporation 2019-08-30
11822-0640-08 2 BLISTER PACK in 1 CARTON (11822-0640-8) / 12 TABLET, FILM... Cold and Flu Relief Severe Daytime Rite Aid Corporation 2019-11-25
11822-5031-08 2 BLISTER PACK in 1 CARTON (11822-5031-8) / 12 TABLET, FILM... Cold and Flu Severe Rite Aid Corporation 2005-08-04
11822-5034-08 1 KIT in 1 CARTON (11822-5034-8) * 8 TABLET, FILM COATED i... Cold and Flu Severe, Daytime, Nighttime Rite Aid Corporation 2021-06-30
11822-6179-08 2 BLISTER PACK in 1 CARTON (11822-6179-8) / 10 TABLET, FILM... Cold and Flu maximum strength Rite Aid Corporation 2021-09-16
36800-0298-04 2 BLISTER PACK in 1 CARTON (36800-298-04) / 10 TABLET, COAT... Mucus Relief Cold and Flu All In One TOPCARE 2021-02-01
36800-0502-05 2 BLISTER PACK in 1 CARTON (36800-502-05) / 12 TABLET, COAT... COLD AND FLU SEVERE TOPCARE 2013-07-01
36800-0581-62 12 BLISTER PACK in 1 CARTON (36800-581-62) / 2 TABLET, FILM... topcare day time cold and flu Topco Associates LLC 2019-09-10
36800-0697-04 2 BLISTER PACK in 1 CARTON (36800-697-04) / 10 TABLET, COAT... Mucus Relief Cold Flu and Sore Throat TOPCO ASSOCIATES LLC 2021-02-01
37000-0524-02 2 TABLET in 1 POUCH (37000-524-02) DayQuil Severe plus Vicks VapoCool Cold and Flu The Procter & Gamble Manufacturing Company 2018-08-01
37808-0178-03 2 BLISTER PACK in 1 CARTON (37808-178-03) / 12 TABLET, COAT... DAYTIME SEVERE COLD AND FLU MAXIMUM STRENGTH HEB 2016-05-01
37808-0286-01 1 KIT in 1 CARTON (37808-286-01) * 8 TABLET, COATED in 1 B... Cold Flu Severe Day Night HEB 2018-03-01
37808-0497-04 2 BLISTER PACK in 1 CARTON (37808-497-04) / 10 TABLET, COAT... Mucus Relief Cold, Flu and Sore Throat HEB 2021-04-27
37808-0598-04 2 BLISTER PACK in 1 CARTON (37808-598-04) / 10 TABLET, COAT... Mucus Relief Cold and Flu HEB 2021-04-27
37808-0663-05 2 BLISTER PACK in 1 CARTON (37808-663-05) / 12 TABLET, COAT... Cold Flu Severe HEB 2018-05-01
41163-0053-08 2 BLISTER PACK in 1 CARTON (41163-053-08) / 12 TABLET, FILM... Severe Cold United Natural Foods, Inc. dba UNFI 2023-01-27
41163-0503-08 2 BLISTER PACK in 1 CARTON (41163-503-08) / 12 TABLET, FILM... daytime severe cold multi-symptom United Natural Foods, Inc. dba UNFI 2005-08-04
41226-0675-24 2 BLISTER PACK in 1 CARTON (41226-675-24) / 12 TABLET, FILM... Daytime Cold and Flu KROGER COMPANY 2025-05-26
41250-0197-04 2 PACKAGE in 1 CARTON (41250-197-04) / 10 TABLET, COATED in... mucus relief cold flu and sore throat Meijer 2021-02-01
41250-0643-08 2 BLISTER PACK in 1 CARTON (41250-643-08) / 12 TABLET, FILM... Cold and Flu Daytime Severe Meijer Distribution Inc 2020-05-08
41250-0663-05 2 BLISTER PACK in 1 CARTON (41250-663-05) / 12 TABLET, COAT... Cold and Flu Severe Meijer 2015-01-01
41250-0840-22 1 KIT in 1 CARTON (41250-840-22) * 8 TABLET, FILM COATED i... DayTime/NiteTime Severe Cold and Flu Maximum Strength Meijer Distribution Inc 2015-08-01
41250-0979-02 2 BLISTER PACK in 1 CARTON (41250-979-02) / 10 TABLET, COAT... mucus relief sinus pressure, pain and cough Meijer 2019-09-01
41250-0981-04 2 BLISTER PACK in 1 CARTON (41250-981-04) / 10 TABLET, COAT... mucus relief all in one cold and flu Meijer 2021-02-01
42507-0163-05 2 BLISTER PACK in 1 CARTON (42507-163-05) / 12 TABLET, COAT... Cold plus Flu Severe HYVEE INC 2025-11-03
42507-0278-03 2 BLISTER PACK in 1 CARTON (42507-278-03) / 12 TABLET, COAT... Severe Cold and Flu HYVEE INC 2026-01-13
46122-0418-62 2 BLISTER PACK in 1 CARTON (46122-418-62) / 12 TABLET, COAT... Cold Flu Severe AmeriSource Bergen 2018-07-01
49035-0053-08 2 BLISTER PACK in 1 CARTON (49035-053-08) / 12 TABLET, FILM... Cold and Flu severe Wal-Mart Stores Inc 2005-08-04
49035-0053-42 12 TABLET, FILM COATED in 1 BLISTER PACK (49035-053-42) Cold and Flu severe Wal-Mart Stores Inc 2005-08-04
49035-0796-02 1 KIT in 1 CARTON (49035-796-02) * 8 BLISTER PACK in 1 KIT... Equate daytime severe vaporice cold and flu nighttime severe vapor ice cold and flu Wal-Mart Stores Inc 2020-07-14
49035-0813-62 12 BLISTER PACK in 1 CARTON (49035-813-62) / 2 TABLET, FILM... equate vapor ice cold and flu Wal-Mart Stores Inc 2020-07-16
49483-0726-64 4 BLISTER PACK in 1 CARTON (49483-726-64) / 1 KIT in 1 BLIS... Maximum strength Day cold and flu and Night severe cold and flu TIME CAP LABORATORIES,INC 2023-09-21
50269-0402-25 25 POUCH in 1 BOX (50269-402-25) / 2 TABLET, FILM COATED in... Tylenol Cold Plus Flu Severe JC World Bell Wholesale Co., Inc. 2018-09-20
50269-0550-01 20 POUCH in 1 BOX (50269-550-01) / 2 TABLET, FILM COATED in... Tylenol Cold Flu Severe JC World Bell Wholesale Co., Inc. 2011-09-01
50580-0402-01 2 TABLET, FILM COATED in 1 POUCH (50580-402-01) TYLENOL Cold Plus Flu Severe Kenvue Brands LLC 2017-07-07
50580-0402-02 50 POUCH in 1 CARTON (50580-402-02) / 2 TABLET, FILM COATED... TYLENOL Cold Plus Flu Severe Kenvue Brands LLC 2017-07-07
50580-0402-26 2 BLISTER PACK in 1 CARTON (50580-402-26) / 12 TABLET, FILM... TYLENOL Cold Plus Flu Severe Kenvue Brands LLC 2012-07-11
50580-0402-72 3 CARTON in 1 PACKAGE (50580-402-72) / 2 BLISTER PACK in 1... TYLENOL Cold Plus Flu Severe Kenvue Brands LLC 2012-07-11
50580-0414-03 3 CARTON in 1 CELLO PACK (50580-414-03) / 1 KIT in 1 CARTON... TYLENOL COLD PLUS FLU SEVERE DAY/NIGHT Kenvue Brands LLC 2016-07-18
50580-0414-04 1 KIT in 1 CARTON (50580-414-04) * 2 BLISTER PACK in 1 CAR... TYLENOL COLD PLUS FLU SEVERE DAY/NIGHT Kenvue Brands LLC 2018-12-21
Observed labelers: Reckitt Benckiser LLC (15) · Lil' Drug Store Products, Inc. (7) · DISCOUNT DRUG MART (6) · Kenvue Brands LLC (6) · Lil Drug Store Products, Inc (6) · CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED (5) · +51 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.