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Acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydrochlo... — RxCUI 2173662

Name: Acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydr… (RxCUI 2173662)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 2173662 Semantic clinical drug · SCD ● Current RxNorm concept 12 FDA products 12 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2173662

Official nameAcetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydrochloride 0.5 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asAPAP 32.5 MG/ML / Dextromethorphan Hydrobromide 1 MG/ML / Phenylephrine Hydrochloride 0.5 MG/ML / Triprolidine Hydrochloride 0.125 MG/ML Oral Solution; acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG / triprolidine HCl 2.5 MG in 20 mL Oral Solution; acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG / triprolidine hydrochloride 1.25 MG per 10 mL Oral Solution; acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG / triprolidine hydrochloride 2.5 MG per 20 mL Oral Solution

FDA products mapped12

Package NDCs mapped12

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
Can I use the nasal spray if I have high blood pressure or heart disease?

📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 32.5 MG/ML / dextromethorphan hydr... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydrochloride 0.5 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution RxCUI 2173662 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 8

The active substance itself — no strength, form, or brand attached yet.
- Acetaminophen 161 IN
- Dextromethorphan 3289 IN
- Phenylephrine 8163 IN
- Triprolidine 10849 IN
- Acetaminophen / dextromethorphan / phenylephrine / triprolidine 2173661 MIN
- Dextromethorphan hydrobromide 102490 PIN
- Phenylephrine hydrochloride 8164 PIN
- Triprolidine hydrochloride 71534 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Acetaminophen / dextromethorphan / phenylephrine / triprolidine Oral Solution 2173660 SCDF
- Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Oral Solution 2648222 SCDFP
- Acetaminophen / dextromethorphan / phenylephrine / triprolidine Oral Liquid Product 2173658 SCDG
- Acetaminophen / dextromethorphan / phenylephrine / triprolidine Oral Product 2173659 SCDG
- Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Oral Liquid Product 2663087 SCDGP
- Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Oral Product 2661608 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 4

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Acetaminophen 32.5 MG/ML 336021 SCDC
- Dextromethorphan hydrobromide 1 MG/ML 1020137 SCDC
- Phenylephrine hydrochloride 0.5 MG/ML 707273 SCDC
- Triprolidine hydrochloride 0.125 MG/ML 1099713 SCDC
Packs 3

Fixed collections of drugs packaged and sold together, like dose packs.
- {1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydrochloride 0.5 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution) } Pack 2637727 GPCK
- {1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydrochloride 0.5 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution) / 1 (acetaminophen 32.5 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack 2397132 GPCK
- {1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydrochloride 0.5 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack 2288826 GPCK

Showing up to 8 concepts per family — 23 of 24 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

{1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydrochloride 0.5 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution) } Pack GPCK · 2637727
{1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydrochloride 0.5 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution) / 1 (acetaminophen 32.5 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack GPCK · 2397132
Acetaminophen 32.5 MG/ML SCDC · 336021
Dextromethorphan hydrobromide 1 MG/ML SCDC · 1020137
Phenylephrine hydrochloride 0.5 MG/ML SCDC · 707273
Triprolidine hydrochloride 0.125 MG/ML SCDC · 1099713
Acetaminophen / dextromethorphan / phenylephrine / triprolidine Oral Solution SCDF · 2173660
Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Oral Solution SCDFP · 2648222
Acetaminophen / dextromethorphan / phenylephrine / triprolidine Oral Liquid Product SCDG · 2173658
Acetaminophen / dextromethorphan / phenylephrine / triprolidine Oral Product SCDG · 2173659

📦 FDA Products & Package NDCs

12 products · 12 package NDCs

12 package NDCs map to RxCUI 2173662 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00363-4278-45	1 KIT in 1 PACKAGE (0363-4278-45) * 177 mL in 1 BOTTLE, PL...	Cold and Flu Daytime Nighttime Severe	Walgreen Company	2023-10-21
00363-8078-45	177 mL in 1 BOTTLE, PLASTIC (0363-8078-45)	Cold and Flu Severe	Walgreen Company	2023-10-21
11673-0286-01	1 KIT in 1 CARTON (11673-286-01) * 180 mL in 1 BOTTLE (116...	Maximum Strength Daytime Cold and Flu and Nighttime Severe Cold and Flu	TARGET CORPORATION	2024-05-01
63824-0115-66	1 KIT in 1 CARTON (63824-115-66) * 180 mL in 1 BOTTLE (638...	Maximum Strength Mucinex Sinus-Max Severe Congestion and Pain and Mucinex Nightshift Sinus	Reckitt Benckiser LLC	2022-05-30
63824-0269-66	180 mL in 1 BOTTLE (63824-269-66)	Mucinex Nightshift Sinus	Reckitt Benckiser LLC	2019-06-15
63824-0504-66	180 mL in 1 BOTTLE (63824-504-66)	Mucinex Nightshift Severe Cold and Flu	Reckitt Benckiser LLC	2020-06-01
63824-0505-26	1 KIT in 1 CARTON (63824-505-26) * 180 mL in 1 BOTTLE (638...	Maximum Strength Mucinex Fast-Max Cold and Flu and Mucinex NightShift Severe Cold and Flu	Reckitt Benckiser LLC	2022-05-30
63824-0959-64	1 BOTTLE in 1 CARTON (63824-959-64) / 118 mL in 1 BOTTLE	Mucinex Childrens FreeFrom Multi-Symptom Cold and Flu Nighttime	Reckitt Benckiser LLC	2020-06-01
69842-0966-06	180 mL in 1 BOTTLE (69842-966-06)	CVS Overnight Cold and Flu Clear and Cool	CVS PHARMACY, INC	2020-03-31
72854-0139-26	1 KIT in 1 CARTON (72854-139-26) * 180 mL in 1 BOTTLE (728...	MUCINEX FAST MAX Liquid Cold and Flu Kickstart and MUCINEX Nightshift Kickstart	Reckitt Benckiser LLC	2023-05-01
72854-0140-66	180 mL in 1 BOTTLE (72854-140-66)	Mucinex Night Time Severe Cold and Flu	Reckitt Benckiser LLC	2023-05-01
72854-0154-26	1 KIT in 1 CARTON (72854-154-26) * 180 mL in 1 BOTTLE (638...	Mucinex Fast-Max Cold and Flu and Mucinex Nighttime Cold and Flu	Reckitt Benckiser LLC	2025-06-01

Observed labelers: Reckitt Benckiser LLC (8) · Walgreen Company (2) · CVS PHARMACY, INC (1) · TARGET CORPORATION (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.