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Hydrochlorothiazide 25 MG / metoprolol tartrate 50 MG Oral Tablet — RxCUI 866482

RxNorm drug concept · Semantic clinical drug
RxCUI 866482 Semantic clinical drug · SCD ● Current RxNorm concept 14 FDA products 35 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI866482
Official nameHydrochlorothiazide 25 MG / metoprolol tartrate 50 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asHCTZ 25 MG / metoprolol tartrate 50 MG Oral Tablet
FDA products mapped14
Package NDCs mapped35
Reported Medicaid activity (SDUD)3,034 prescriptions · 11 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Hydrochlorothiazide: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It's a water pill — it makes your kidneys flush out extra salt and water, which reduces the amount of fluid your body is holding. That directly lowers your blood pressure and reduc...
  • What exactly is hydrochlorothiazide supposed to do for me?
  • You can take it either way, but be consistent — take it the same way each time. Food does reduce absorption slightly, but what matters most is that you take it regularly as prescri...
  • Should I take it with food or on an empty stomach?
📖 Read our full Hydrochlorothiazide guide →

🕸️ Concept Web — How Hydrochlorothiazide 25 MG / metoprolol tartrate... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Hydrochlorothiazide 25 MG / metoprolol tartrate 50 MG Oral Tablet RxCUI 866482

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 4

    The active substance itself — no strength, form, or brand attached yet.

    • Hydrochlorothiazide 5487
    • Metoprolol 6918
    • Hydrochlorothiazide / metoprolol 214621
    • Metoprolol tartrate 203191
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Lopressor HCT 218072
  3. Dose forms 13

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Hydrochlorothiazide / metoprolol Oral Tablet 372889
    • Hydrochlorothiazide / metoprolol tartrate Oral Tablet 2647670
    • Hydrochlorothiazide / metoprolol Oral Product 1162132
    • Hydrochlorothiazide / metoprolol Pill 1162133
    • Hydrochlorothiazide / metoprolol tartrate Oral Product 2661251
    • Hydrochlorothiazide / metoprolol tartrate Pill 2662617
    • Hydrochlorothiazide / metoprolol Oral Tablet [Lopressor HCT] 866497
    • Hydrochlorothiazide / metoprolol tartrate Oral Tablet [Lopressor HCT] 2656204
    • +5 more in this family
  4. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Hydrochlorothiazide 25 MG 316049
    • Metoprolol tartrate 50 MG 866435
    • Hydrochlorothiazide 25 MG / metoprolol tartrate 50 MG Oral Tablet [Lopressor HCT] 866502
    • Hydrochlorothiazide 25 MG / metoprolol tartrate 50 MG [Lopressor HCT] 866500

Showing up to 8 concepts per family — 17 of 22 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Hydrochlorothiazide 25 MG SCDC · 316049
  • Metoprolol tartrate 50 MG SCDC · 866435
  • Hydrochlorothiazide / metoprolol Oral Tablet SCDF · 372889
  • Hydrochlorothiazide / metoprolol tartrate Oral Tablet SCDFP · 2647670
  • Hydrochlorothiazide / metoprolol Oral Product SCDG · 1162132
  • Hydrochlorothiazide / metoprolol Pill SCDG · 1162133
  • Hydrochlorothiazide / metoprolol tartrate Oral Product SCDGP · 2661251
  • Hydrochlorothiazide / metoprolol tartrate Pill SCDGP · 2662617

Brand-Name Concepts

  • Hydrochlorothiazide 25 MG / metoprolol tartrate 50 MG Oral Tablet [Lopressor HCT] SBD · 866502
  • Hydrochlorothiazide 25 MG / metoprolol tartrate 50 MG [Lopressor HCT] SBDC · 866500
  • Hydrochlorothiazide / metoprolol Oral Tablet [Lopressor HCT] SBDF · 866497
  • Hydrochlorothiazide / metoprolol tartrate Oral Tablet [Lopressor HCT] SBDFP · 2656204
  • Lopressor HCT Oral Product SBDG · 1180272
  • Lopressor HCT Pill SBDG · 1180275
  • Lopressor HCT BN · 218072

📦 FDA Products & Package NDCs

14 products · 35 package NDCs
35 package NDCs map to RxCUI 866482 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00378-0424-01 100 TABLET in 1 BOTTLE, PLASTIC (0378-0424-01) Metoprolol Tartrate and Hydrochlorothiazide Mylan Pharmaceuticals Inc. 2004-08-20
00378-0434-01 100 TABLET in 1 BOTTLE, PLASTIC (0378-0434-01) Metoprolol Tartrate and Hydrochlorothiazide Mylan Pharmaceuticals Inc. 2004-08-20
00378-0445-01 100 TABLET in 1 BOTTLE, PLASTIC (0378-0445-01) Metoprolol Tartrate and Hydrochlorothiazide Mylan Pharmaceuticals Inc. 2004-08-20
27241-0301-01 100 TABLET in 1 BOTTLE (27241-301-01) METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE Ajanta Pharma USA Inc. 2025-03-15
27241-0302-01 100 TABLET in 1 BOTTLE (27241-302-01) METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE Ajanta Pharma USA Inc. 2025-03-15
46708-0115-01 1000 TABLET in 1 BOTTLE (46708-115-01) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Limited 2013-09-17
46708-0115-10 100 TABLET in 1 BOTTLE (46708-115-10) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Limited 2013-09-17
46708-0115-30 30 TABLET in 1 BOTTLE (46708-115-30) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Limited 2013-09-17
46708-0116-10 100 TABLET in 1 BOTTLE (46708-116-10) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Limited 2013-09-17
46708-0116-30 30 TABLET in 1 BOTTLE (46708-116-30) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Limited 2013-09-17
46708-0116-50 500 TABLET in 1 BOTTLE (46708-116-50) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Limited 2013-09-17
46708-0117-10 100 TABLET in 1 BOTTLE (46708-117-10) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Limited 2013-09-17
46708-0117-30 30 TABLET in 1 BOTTLE (46708-117-30) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Limited 2013-09-17
46708-0117-50 500 TABLET in 1 BOTTLE (46708-117-50) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Limited 2013-09-17
62332-0115-30 30 TABLET in 1 BOTTLE (62332-115-30) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Inc. 2015-10-15
62332-0115-31 100 TABLET in 1 BOTTLE (62332-115-31) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Inc. 2015-10-15
62332-0115-91 1000 TABLET in 1 BOTTLE (62332-115-91) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Inc. 2015-10-15
62332-0116-30 30 TABLET in 1 BOTTLE (62332-116-30) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Inc. 2015-10-15
62332-0116-31 100 TABLET in 1 BOTTLE (62332-116-31) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Inc. 2015-10-15
62332-0116-71 500 TABLET in 1 BOTTLE (62332-116-71) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Inc. 2015-10-15
62332-0117-30 30 TABLET in 1 BOTTLE (62332-117-30) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Inc. 2015-10-15
62332-0117-31 100 TABLET in 1 BOTTLE (62332-117-31) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Inc. 2015-10-15
62332-0117-71 500 TABLET in 1 BOTTLE (62332-117-71) Metoprolol Tartrate and Hydrochlorothiazide Alembic Pharmaceuticals Inc. 2015-10-15
62756-0368-08 100 TABLET in 1 BOTTLE (62756-368-08) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0368-18 1000 TABLET in 1 BOTTLE (62756-368-18) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0368-83 30 TABLET in 1 BOTTLE (62756-368-83) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0368-88 100 TABLET in 1 BOTTLE (62756-368-88) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0369-08 100 TABLET in 1 BOTTLE (62756-369-08) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0369-18 1000 TABLET in 1 BOTTLE (62756-369-18) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0369-83 30 TABLET in 1 BOTTLE (62756-369-83) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0369-88 100 TABLET in 1 BOTTLE (62756-369-88) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0370-08 100 TABLET in 1 BOTTLE (62756-370-08) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0370-18 1000 TABLET in 1 BOTTLE (62756-370-18) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0370-83 30 TABLET in 1 BOTTLE (62756-370-83) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
62756-0370-88 100 TABLET in 1 BOTTLE (62756-370-88) Metoprolol Tartrate and Hydrochlorothiazide Sun Pharmaceutical Industries, Inc. 2022-04-01
Observed labelers: Sun Pharmaceutical Industries, Inc. (12) · Alembic Pharmaceuticals Inc. (9) · Alembic Pharmaceuticals Limited (9) · Mylan Pharmaceuticals Inc. (3) · Ajanta Pharma USA Inc. (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.