Acetaminophen
33 interactions 489 cited referencesAcetaminophen is a pain reliever and fever reducer used to treat mild to moderate pain and reduce fever. Read the full Acetaminophen drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Acetaminophen Articaine An increased risk of methemoglobinemia Details Acetaminophen Carbamazepine Carbatrol An increased risk of acetaminophen hepatotoxicity and reduced acetaminophen exposure Details Acetaminophen Exenatide Bydureon Reduced oral acetaminophen absorption and reduced efficacy of oral acetaminophen Details Acetaminophen Flucloxacillin An increased risk of high anion gap metabolic acidosis (HAGMA) Details Acetaminophen Imatinib Gleevec Increased acetaminophen levels Details Acetaminophen Isoniazid An increased risk of hepatotoxicity Details Acetaminophen Lidocaine Akten An increased risk of methemoglobinemia Details Acetaminophen Pixantrone Increased CYP1A2 substrate exposure Details Acetaminophen Pneumococcal 13-Valent Vaccine, Diphtheria Conjugate An inadequate immunologic response to the vaccine Details Acetaminophen Probenecid Increased risk of acetaminophen exposure and an increased risk of acetaminophen-related adverse reactions Details Acetaminophen Exenatide Injection Bydureon Reduced oral acetaminophen absorption and reduced efficacy of oral acetaminophen DetailsNo interactions on this page match that filter — try the next page or clear the filter.
Check another drug
Still have questions about this combination?
Every question gets a real answer from a licensed pharmacist — free, and usually within a day.
Ask the pharmacist