Asenapine Transdermal Patch

377 interactions 1 explained in plain English 412 cited references

Also sold as: Secuado Secuado®

About Asenapine Transdermal Patch

Asenapine transdermal patches are used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Asenapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain… Read the full Asenapine Transdermal Patch drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Mesoridazine Metoclopramide Pimozide Piperaquine Bepridil

15 Contraindicated 276 Major 86 Moderate

All (377) Contraindicated (15) Major (276) Moderate (86)

Major

Asenapine Transdermal Patch Sulpiride An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sultopride Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sunitinib Sutent Increased risk of QT interval prolongation and an increased risk of torsade de pointes Details Asenapine Transdermal Patch Tacrolimus Astagraf An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Taletrectinib Ibtrozi Increased risk of QT interval prolongation and torsade de pointes Details Asenapine Transdermal Patch Tamoxifen Nolvadex® Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Tapentadol Nucynta An increased risk of respiratory and CNS depression Details Asenapine Transdermal Patch Telaprevir Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Telavancin Vibativ Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Telithromycin Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Tetrabenazine Xenazine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Tolterodine Detrol Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Topiramate Eprontia An increased risk of CNS depression Details Asenapine Transdermal Patch Toremifene Fareston Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Tramadol ConZip Increased traMADol exposure, reduced exposure of the active metabolite and an increased risk of CNS depression Details Asenapine Transdermal Patch Tranylcypromine Parnate An increased risk of CNS depression Details Asenapine Transdermal Patch Trazodone Raldesy Increased risk of CNS depression and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Triclabendazole Egaten An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Trifluoperazine An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Trimipramine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Triptorelin Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Vandetanib Caprelsa An increased risk of QT interval prolongation and torsades de pointes Details Asenapine Transdermal Patch Vardenafil Levitra An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Vemurafenib Zelboraf Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Venlafaxine Increased venlafaxine exposure, an increased asenapine exposure and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Vepdegestrant Veppanu An increased risk of QT interval prolongation and an increased risk of torsade de pointes, polymorphic ventricular tachycardia, ot... Details Asenapine Transdermal Patch Vilanterol An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Vinflunine Increased risk of QT-interval prolongation Details Asenapine Transdermal Patch Voclosporin Lupkynis An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Voriconazole Vfend An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Vorinostat Zolinza Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Ziftomenib Komzifti An increased risk of QT interval prolongation and torsade de pointes Details Asenapine Transdermal Patch Zolpidem Ambien An increased risk of CNS depression, complex sleep behaviors and respiratory depression Details Asenapine Transdermal Patch Zotepine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Zuclopenthixol An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Zuranolone Zurzuvae An increased risk of CNS depression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.