Atropine Ophthalmic

Name: Atropine Ophthalmic Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

64 interactions 238 cited references

Also sold as: Atropine Care 1% Atropisol® Isopto® Atropine Ocu-Tropine®

About Atropine Ophthalmic

Ophthalmic atropine is used before eye examinations to dilate (open) the pupil, the black part of the eye through which you see. It is also used to relieve pain caused by swelling and inflammation of the eye. Read the full Atropine Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ambenonium Potassium Citrate Potassium Chloride Alfentanil Amantadine Amifampridine

3 Contraindicated 54 Major 4 Moderate 3 Minor

All (64) Contraindicated (3) Major (54) Moderate (4) Minor (3)

Minor

Atropine Ophthalmic Belladonna Excessive anticholinergic activity (severe dry mouth, constipation, decreased urination, excessive sedation, blurred vision) Details Atropine Ophthalmic Belladonna Alkaloids Excessive anticholinergic activity (severe dry mouth, constipation, decreased urination, excessive sedation, blurred vision) Details Atropine Ophthalmic Cisapride Propulsid® Loss of cisapride efficacy Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.