FDA-filed SPL labeling · retrieved through openFDA

Atropine

Atropine is an anticholinergic medication used across multiple injectable and ophthalmic products to treat poisoning by nerve agents or insecticides, slow heart rate emergencies (symptomatic bradycardia and cardiac arrest), and eye conditions including dilated pupils and lazy eye therapy.

Brand names Isopto AtropineATROPEN Auto-Injector
Drug classes ⓘ Anticholinergic
Rx Forms 3 Routes Intravenous · Ophthalmic · Intramuscular; Intravenous; Subcutaneous · Endotracheal, Intramedullary, Intramuscular, Intravenous, Subcutaneous +7
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 50 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveSep 15, 2022
Clinical labels in scope ⓘ50
AvailabilityRx
Earliest approval/marketing year ⓘ1971
FDA-listed product records ⓘ192
Boxed warningNone found in compared labels
How we combine label and product data →
Other forms & routes:
Ophthalmic
⭐ Atropine at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Atropine is a powerful anticholinergic drug used in serious medical situations — from nerve agent poisoning and cardiac emergencies to surgical preparation and eye procedures. It is always given by a healthcare professional or in a supervised emergency setting, so the dose and route are carefully matched to the situation. Because it can significantly affect the heart, eyes, bladder, and ability to sweat, it needs close monitoring, especially in children, older adults, and anyone with heart or lung disease.
How we write & review this content — our editorial policy →

📖 Atropine: Patient Information Guide

A plain-language walkthrough of Atropine — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

Atropine is used across several products and routes for a wide range of urgent medical situations and eye conditions.

  • Injectable atropine (Atropine Sulfate) treats symptomatic bradycardia (dangerously slow heart rate) and bradyasystolic cardiac arrest
  • Injectable atropine acts as an antidote for poisoning by organophosphorus nerve agents, carbamate insecticides, and muscarinic mushrooms
  • ATROPEN Auto-Injector is specifically approved for treating organophosphorus nerve agent or carbamate insecticide poisoning in adults and children
  • Parenteral Atropine Sulfate is used before and during surgery to reduce saliva and airway secretions and to suppress unwanted nerve reflexes
  • Injectable atropine is used to relieve spasms of the gastrointestinal tract, including pylorospasm and hypermotility of the colon
  • Injectable atropine is used to relax the GI tract during certain imaging procedures (hypotonic radiography)
  • Injectable atropine is used for ureteral and biliary colic (spasm-related pain), bronchial spasm, and urinary tract disorders involving bladder muscle overactivity
  • Injectable atropine has been used to help manage parkinsonism-related rigidity and tremor, peptic ulcer, and excess secretions from rhinitis or hay fever
  • Atropine sulfate and Isopto Atropine eye drops are used for pupil dilation (mydriasis), cycloplegia, and penalization of the healthy eye in amblyopia (lazy eye) treatment in adults and children aged 3 months and older
  • Atropine Sulfate eye ointment is used for mydriasis, cycloplegia, and cycloplegic refraction, and for pupil dilation in inflammatory conditions of the iris and uveal tract
⚙️How it works▾

Atropine blocks a set of receptors in the body called muscarinic receptors — the sites that normally respond to the nerve chemical acetylcholine. By blocking these receptors, atropine prevents acetylcholine from slowing the heart, triggering gland secretions, tightening smooth muscle in the gut and airways, or constricting the pupil. In poisoning by nerve agents or certain insecticides, those chemicals cause an overwhelming flood of acetylcholine activity; atropine counters that flood by blocking the receptors acetylcholine would normally hit.

This blockade is competitive — meaning a high enough concentration of acetylcholine can still partially overcome it. That's why repeated or large doses are sometimes needed in severe poisoning situations.

💊How it's taken▾

Atropine is always given by a healthcare professional — the right route and timing depend entirely on what it's being used for.

  • Injectable forms may be given intravenously (IV), intramuscularly (IM), subcutaneously (under the skin), or by other routes depending on the clinical situation; IV is usually preferred when available
  • The ATROPEN Auto-Injector is injected into the mid-outer thigh in an emergency and is a single-dose device; three auto-injectors are recommended to be available for each person at risk
  • Eye drops and eye ointment are applied directly to the eye; your prescriber will specify how often
  • Always follow the prescriber's exact instructions — do not adjust the dose or frequency on your own
🤒Side effects — in detail▾

The most common side effects of atropine are direct results of its action on the body's nervous system.

  • Dry mouth
  • Blurred vision and light sensitivity (photophobia)
  • Fast heart rate (tachycardia) and palpitations
  • Flushing, warm or dry skin
  • Difficulty urinating or inability to urinate
  • Constipation, abdominal bloating, nausea, or vomiting
  • Headache and dizziness
  • Confusion, especially at higher doses

More serious reactions — including severe heart rhythm problems, hallucinations, seizures, high fever from inability to sweat, acute glaucoma, and severe allergic reactions — require emergency medical attention right away.

⚠️Warnings & precautions▾
  • Heart risks: Atropine can cause fast or irregular heart rhythms. In people with coronary artery disease or a recent heart attack, it may trigger or worsen a heart attack. Use only under close monitoring in anyone with heart disease.
  • Dangerous overheating: Atropine blocks sweating. In warm environments or during exercise, this can lead to high fever and heat injury — especially in children and after accidental injection.
  • Acute glaucoma: Atropine can raise pressure inside the eye and trigger acute glaucoma in susceptible individuals. Tell your doctor if you have narrow-angle glaucoma or are at risk.
  • Urinary retention: Atropine can make it difficult or impossible to urinate, especially in people with bladder outflow problems.
  • Bowel obstruction: In people with partial pyloric stenosis, atropine may cause complete blockage; watch for GI symptoms.
  • Chronic lung disease: Atropine can thicken airway secretions, making breathing harder in people with chronic lung conditions.
  • Severe allergic reactions: Anaphylaxis has been reported; seek emergency care for throat swelling, hives, or breathing difficulty.
🔀What it interacts with▾

Atropine has a small number of documented drug interactions to be aware of.

  • Pralidoxime: When used together with atropine for nerve agent poisoning, pralidoxime can make atropine's effects appear sooner and more strongly — watch for early signs like rapid heart rate, flushing, and dry mouth
  • Barbiturates: Atropine can increase the sedative effect of barbiturates; use together very cautiously, particularly if treating seizures related to atropine toxicity

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it▾
  • Tell your doctor about any heart disease, recent heart attack, or heart rhythm problems — atropine significantly affects heart rate and rhythm
  • Tell your doctor if you have narrow-angle glaucoma or are at risk — atropine can trigger an acute attack
  • Tell your doctor if you have trouble urinating or a known bladder obstruction
  • Tell your doctor if you have chronic lung disease — atropine can thicken secretions in the airways
  • Tell your doctor if you have partial pyloric stenosis — atropine may cause complete bowel obstruction
  • Pregnant women: atropine crosses the placenta and reaches the fetus; in a life-threatening emergency, treatment should not be withheld, but discuss all risks with your doctor
  • Breastfeeding mothers: trace amounts appear in breast milk; consider pumping and discarding milk for 24 hours after a dose before resuming breastfeeding
  • Children under 2 and adults over 65 clear atropine more slowly — effects may be more intense and longer-lasting; dosing should be cautious
  • Tell your doctor about any prior allergic reaction to atropine
🚑If you take too much▾

Too much atropine causes a recognizable pattern: flushed dry skin, very fast heart rate, widely dilated pupils that don't respond to light, high fever, and blurred vision. At higher levels, a person may become confused, disoriented, or have hallucinations, delirium, or seizures — effects that can last 48 hours or more. In the most severe cases, breathing can fail, coma can develop, and the outcome can be fatal.

Treatment is supportive — maintaining breathing, controlling body temperature (especially in children), managing agitation with a benzodiazepine if needed, and keeping urine output up. Anyone suspected of atropine overdose needs emergency medical care immediately.

📡Pharmacodynamics — effects in the body▾

Atropine's most clinically visible effect is speeding up a slow heart rate by releasing the heart from the braking influence of the vagus nerve. It also dries up secretions from salivary, bronchial, and sweat glands, relaxes smooth muscle in the gut and airways, and widens the pupil. One important caution: at very small doses, atropine can briefly slow the heart before the expected speedup occurs. Large or repeated doses can actually depress breathing rather than stimulate it, and occasionally a large dose causes an abnormal heart rhythm called atrioventricular (A-V) block.

🔬Pharmacokinetics — how your body processes it▾

After an intramuscular injection, atropine is absorbed quickly, with peak blood levels reached around 30 minutes after the shot — and physical activity after the injection can significantly increase how much is absorbed. Atropine is distributed widely throughout the body, crosses the placenta, and appears in breast milk in small amounts. It is mainly broken down in the liver, with 13–50% excreted unchanged by the kidneys, and has a half-life of about 2 to 4 hours in most adults.

Children under 2 and adults over 65 eliminate atropine more than twice as slowly as other age groups, meaning effects last longer in these populations. Notably, organophosphate pesticides can slow the breakdown of atropine in the body.

📦How to store it▾

Store between 20ºC to 25ºC (68ºF to 77ºF); excursions permitted between 15ºC and 30ºC (between 59ºF and 86ºF) . Protect from light.

📄 Written from Atropine’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Atropine — the kind of thing our pharmacy team would talk through with you at the counter.

Why is atropine being given to me — what does it actually do? ▾
Atropine works by blocking certain nerve signals that control things like your heart rate, gland secretions, and muscle activity. Depending on your situation, it might be used to speed up a dangerously slow heart rate, dry up excess secretions before surgery, treat poisoning from nerve agents or certain pesticides, or dilate your pupils for an eye exam or procedure. Your doctor or care team chose it because it's the right tool for what's happening in your body right now.
What side effects should I expect, and which ones should make me call for help? ▾
Common effects you might notice include a dry mouth, blurred vision, light sensitivity, a faster heartbeat, flushing or warm skin, and some difficulty urinating. These are expected responses to how the drug works. You should seek medical help right away if you experience chest pain or a racing or very irregular heartbeat, sudden severe eye pain, inability to urinate at all, a high fever — especially if you've been in a warm environment — or severe confusion, hallucinations, or seizures. Those are serious signals that need prompt attention.
I received an ATROPEN injection in an emergency. What should I do next? ▾
ATROPEN is designed as a first-response treatment — not a complete one. After using it, you need to get to a hospital or emergency medical facility as quickly as possible. Avoid vigorous physical activity and try to stay in a cool environment, because atropine reduces your ability to sweat and can cause dangerous overheating. If the injection was given accidentally to someone who wasn't poisoned by a nerve agent, that person should still seek medical care right away, as the drug has real effects on the heart and nervous system even in healthy people.
Is atropine safe during pregnancy or while breastfeeding? ▾
Atropine does cross the placenta and reach the baby, and trace amounts show up in breast milk. That said, if you're facing a life-threatening emergency — like severe poisoning or cardiac arrest — the danger of not treating you is far greater than the risk to the baby, so treatment should not be withheld. If you've received atropine while breastfeeding, consider pumping and discarding your milk for 24 hours before nursing again. Always let your care team know you're pregnant or breastfeeding so they can factor that in.
Are there any medicines I should tell my doctor about before getting atropine? ▾
Yes — two main ones stand out. If you're also being given pralidoxime (commonly used alongside atropine in nerve agent poisoning treatment), the effects of atropine can kick in more quickly and feel more intense, so your team will watch you closely. If you take barbiturates — a type of sedative — atropine can increase their effects, so extra caution is needed. Let your care team know everything you take, including any other prescriptions, over-the-counter medications, and supplements.
My child needs atropine — is it safe for kids, and are there any special concerns? ▾
Yes, atropine is used in children, including infants 3 months and older for the eye drop formulations, and in pediatric patients of all ages for poisoning emergencies with the ATROPEN Auto-Injector. That said, children — especially those under 2 — clear the drug more slowly than adults, which means the effects can be stronger and last longer. Watch for the same side effects as in adults, though children may show signs like confusion or agitation at lower doses. Your child's dose is based on their weight, and their care team will monitor them carefully.
Is Atropine available over the counter? ▾
Atropine is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.
When was Atropine first available? ▾
Atropine has been available in the United States since at least 1971, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Atropine? ▾
Atropine is supplied by 51 manufacturers listed in the FDA NDC Directory, including Medical Purchasing Solutions, LLC, HF Acquisition Co LLC, DBA HealthFirst, Henry Schein, Inc..

💬 Answers drafted from Atropine’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

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💊 How Atropine comes

Atropine is available in 3 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Injection

Endotracheal · Into a muscle · Into a vein · Intramedullary · Intravascular · Parenteral · Under the skin
Brands ATROPEN Auto-Injector
How this form is used
What it may be used for
  • ATROPEN Auto-Injector is specifically indicated for treating poisoning by organophosphorus nerve agents or carbamate insecticides in adults and children
  • Atropine Sulfate injection is used to temporarily block severe or life-threatening muscarinic effects, including treatment of symptomatic bradycardia (dangerously slow heart rate) and cardiac arrest
  • Atropine Sulfate injection is used as an antidote for organophosphorus, carbamate, or muscarinic mushroom poisoning
  • Parenteral atropine sulfate is used as a pre-surgical medication to reduce saliva and airway secretions, and for gastrointestinal spasms and ureteral or biliary colic
Important instructions
  • ATROPEN Auto-Injector is given as a single-dose injection into the mid-outer thigh; it is intended as initial emergency treatment — seek definitive medical care immediately after use
  • Atropine Sulfate injection is given by a healthcare professional; intravenous administration is usually preferred, but intramuscular, subcutaneous, endotracheal, and intraosseous routes are possible depending on the clinical situation
  • Inspect all injectable atropine solutions for particles or discoloration before use; do not use if the solution is not clear or the seal is not intact
  • After first opening, discard any unused portion of Atropine Sulfate injection within 24 hours
Available strengths 8 strengths
0.05 mg/mL 0.1 mg/mL 0.25 mg/0.3 mL 0.4 mg/mL 0.5 mg/0.7 mL 1 mg/0.7 mL
Show 2 more strengths Show fewer strengths
1 mg/mL 2 mg/0.7 mL
126 FDA-listed product records ⓘ

Eye drops

In the eye
Brands Isopto Atropine
How this form is used
What it may be used for
  • Atropine sulfate ophthalmic solution is used to dilate the pupil (mydriasis) and temporarily paralyze the eye's focusing muscle (cycloplegia) in adults and children 3 months and older
  • Isopto Atropine 1% is used for pupil dilation (mydriasis) and cycloplegia
  • Both Atropine sulfate and Isopto Atropine 1% are used to penalize the healthy eye in the treatment of lazy eye (amblyopia)
Important instructions
  • Apply Atropine sulfate or Isopto Atropine eye drops directly to the eye as directed by your prescriber
  • Follow your prescriber's instructions for frequency — do not use more often than directed
  • Atropine sulfate ophthalmic solution is indicated for patients aged 3 months and older
Available strengths 1 strength
10 mg/mL
44 FDA-listed product records ⓘ

Eye ointment

In the eye
How this form is used
What it may be used for
  • Atropine Sulfate eye ointment is used for pupil dilation (mydriasis) and cycloplegia
  • Atropine Sulfate eye ointment is used for cycloplegic refraction and for pupil dilation in inflammatory conditions of the iris and uveal tract
Important instructions
  • Apply Atropine Sulfate eye ointment to the eye as directed by your prescriber
  • Follow all instructions on the label regarding frequency and amount
Available strengths 1 strength
10 mg/g
3 FDA-listed product records ⓘ

📊 Atropine across the U.S. market

How Atropine appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

3
Dose forms ⓘ
51
Manufacturers
4
Brand names
192
FDA-listed product records ⓘ
1971
First marketed ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (19) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Medical Purchasing Solutions, LLC11%
HF Acquisition Co LLC, DBA HealthFirst9%
Henry Schein, Inc.9%
A-S Medication Solutions5%
Amneal Pharmaceuticals NY LLC5%
Somerset Therapeutics, LLC4%
Other makers57%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Atropine is used

A general measure of how commonly Atropine is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Atropine is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

111,807
Medicaid prescriptions filled (Q1–Q4 2025)
$5.4M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Atropine prescribed? Of the 1,597 medications we measure, Atropine ranks #494 by Medicaid prescriptions — more than 69% of them.

Where Atropine ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #494 of 1,597
#489 Palonosetron Injection 116,599 Rx #490 Cefpodoxime 115,402 Rx #491 Magnesium Sulfate Hept... 113,083 Rx #492 Nystatin and Triamcino... 112,193 Rx #493 Vancomycin Injection 112,053 Rx #494 Atropine 111,807 Rx #495 Lifitegrast Ophthalmic 109,594 Rx #496 Midazolam Nasal Spray 109,459 Rx #497 Digoxin 109,371 Rx #498 Upadacitinib 108,976 Rx #499 Chlordiazepoxide 107,446 Rx

Utilization by Atropine product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 10 mg/mL ophthalmic solution is the most-dispensed Atropine product — about 90% of these Medicaid prescriptions.

atropine sulfate 10 MG/ML Ophthalmic Solution Most dispensed

100,738 Medicaid prescriptions (Q1–Q4 2025) 90% of Atropine prescriptions shown $4.5M gross reimbursement (before rebates) ≈ $45 per prescription (gross)

Summed across the 18 of 41 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1190655

1 ML atropine sulfate 0.4 MG/ML Injection

7,865 Medicaid prescriptions (Q1–Q4 2025) 7% of Atropine prescriptions shown $668,426 gross reimbursement (before rebates) ≈ $85 per prescription (gross)

Summed across the 2 of 17 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1666781

10 ML atropine sulfate 0.1 MG/ML Prefilled Syringe

1,113 Medicaid prescriptions (Q1–Q4 2025) <1% of Atropine prescriptions shown $104,251 gross reimbursement (before rebates) ≈ $94 per prescription (gross)

Summed across the 3 of 30 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1190546

atropine sulfate 0.4 MG/ML Injectable Solution

1,058 Medicaid prescriptions (Q1–Q4 2025) <1% of Atropine prescriptions shown $30,389 gross reimbursement (before rebates) ≈ $29 per prescription (gross)

Summed across the 3 of 33 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1190776

1 ML atropine sulfate 1 MG/ML Injection

1,033 Medicaid prescriptions (Q1–Q4 2025) <1% of Atropine prescriptions shown $38,041 gross reimbursement (before rebates) ≈ $37 per prescription (gross)

Summed across the 3 of 17 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1190795

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Atropine, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 29 of 138 listed Atropine NDCs with Medicaid activity.

🔍 Compare Atropine products

A representative set of FDA-listed product records for Atropine — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 192 of 192 products — FDA National Drug Code Directory. See every product, package size and price: browse all 192 Atropine NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Atropine RxCUI 1223 7 dose forms · 28 strengths
  2. Dose form (SCDF) Injectable Solution RxCUI 370624 In current FDA listings
    Clinical drug / strength (SCD) sulfate 0.3 MG/ML RxCUI 1190764 sulfate 0.4 MG/ML RxCUI 1190776 sulfate 0.54 MG/ML RxCUI 1145629 sulfate 0.6 MG/ML RxCUI 1190787 sulfate 1.25 MG/ML RxCUI 1190800
  4. Dose form (SCDF) Ophthalmic Ointment RxCUI 374552 In current FDA listings
    Clinical drug / strength (SCD) sulfate 0.005 MG/MG RxCUI 1190563 sulfate 0.01 MG/MG RxCUI 1190570
  5. Dose form (SCDF) Ophthalmic Solution RxCUI 370964 In current FDA listings
    Clinical drug / strength (SCD) sulfate 0.31 MG/ML RxCUI 1190766 sulfate 0.62 MG/ML RxCUI 1190790 sulfate 1 MG/ML RxCUI 1190796 sulfate 1.25 MG/ML RxCUI 1190801 sulfate 10 MG/ML RxCUI 1190655 sulfate 2.5 MG/ML RxCUI 1190806 sulfate 20 MG/ML RxCUI 1190817 sulfate 5 MG/ML RxCUI 1190668
  6. Dose form (SCDF) Oral Tablet RxCUI 370625 No current FDA listing
    Clinical drug / strength (SCD) sulfate 0.4 MG RxCUI 1190692 sulfate 0.6 MG RxCUI 1190783

Look up RxCUI 1223 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Isopto Atropine ATROPEN Auto-Injector

🏭 Manufacturers & labelers

Medical Purchasing Solutions, LLC 20 HF Acquisition Co LLC, DBA HealthFirst 17 Henry Schein, Inc. 16 A-S Medication Solutions 9 Amneal Pharmaceuticals NY LLC 9 Somerset Therapeutics, LLC 7 Accord Healthcare Inc. 6 Accord Healthcare, Inc., 6 Lifestar Pharma LLC 6 Remedyrepack Inc. 6 Hospira, Inc. 6 ProPharma Distribution 5 Meridian Medical Technologies LLC 5 Hikma Pharmaceuticals USA Inc. 5 Amneal Pharmaceuticals LLC 5 Bausch & Lomb Incorporated 4 American Regent, Inc. 4 General Injectables & Vaccines, Inc 4 Akorn 3 Alcon Laboratories, Inc. 3 Apotex Corp. 3 Gland Pharma Limited 3 Boehringer Ingelheim Pharma GmbH and Co. KG 2 Bausch & Lomb Americas Inc. 2

…and 16 more on the FDA NDC directory.

RxNorm drug class

Atropine belongs to the Anticholinergic class.

Pharmacologic class Anticholinergic, Cholinergic Muscarinic Antagonist
Drug family (ATC) Belladonna alkaloids, tertiary amines, Anticholinergics, Antidotes
How it works Cholinergic Muscarinic Antagonists, Cholinergic Antagonists

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Sep 15, 2022
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Atropine.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Atropine after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
50
NDC products indexed
192
Distinct labelers/manufacturers represented
51
Linked representative label ⓘ
Meridian Medical Technologies LLC
Linked label effective
Sep 15, 2022
Composite sections available
22
Linked SPL Set ID
e2d4307d-da8f-49f5-aac0-02355dd9ffb7
Linked SPL Document ID
f1736bb6-219c-48dd-969d-f26f6fbad350
Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 50 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Meridian Medical Technologies LLC is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.