Chlordiazepoxide

Generic name: Pronounced as (klor dye az e pox' ide)
Brand names
  • A-poxide®
  • Chlordiazachel®
  • H-Tran®
  • Librax® (as a combination product containing Clidinium, Chlordiazepoxide)
  • Librelease®
  • Libritabs®
  • Librium®
  • Lygen®
  • Mitran®
  • Poxi®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 05/15/2021

Chlordiazepoxide may increase the risk of serious or life-threatening breathing problems, sedation, or coma if used along with certain medications. Tell your doctor if you are taking or plan to take certain opiate medications for cough such as codeine (in Triacin-C, in Tuzistra XR) or hydrocodone (in Anexsia, in Norco, in Zyfrel) or for pain such as codeine (in Fiorinal), fentanyl (Actiq, Duragesic, Subsys, others), hydromorphone (Dilaudid, Exalgo), meperidine (Demerol), methadone (Dolophine, Methadose), morphine (Astramorph, Duramorph PF, Kadian), oxycodone (in Oxycet, in Percocet, in Roxicet, others), and tramadol (Conzip, Ultram, in Ultracet). Your doctor may need to change the dosages of your medications and will monitor you carefully. If you take chlordiazepoxide with any of these medications and you develop any of the following symptoms, call your doctor immediately or seek emergency medical care immediately: unusual dizziness, lightheadedness, extreme sleepiness, slowed or difficult breathing, or unresponsiveness. Be sure that your caregiver or family members know which symptoms may be serious so they can call the doctor or emergency medical care if you are unable to seek treatment on your own.

Chlordiazepoxide may be habit forming. Do not take a larger dose, take it more often, or for a longer time than your doctor tells you to. Tell your doctor if you have ever drunk large amounts of alcohol, if you use or have ever used street drugs, or have overused prescription medications. Do not drink alcohol or use street drugs during your treatment. Drinking alcohol or using street drugs during your treatment with chlordiazepoxide also increases the risk that you will experience these serious, life-threatening side effects. Also tell your doctor if you have or have ever had depression or another mental illness.

Chlordiazepoxide may cause a physical dependence (a condition in which unpleasant physical symptoms occur if a medication is suddenly stopped or taken in smaller doses), especially if you take it for several days to several weeks. Do not stop taking this medication or take fewer doses without talking to your doctor. Stopping chlordiazepoxide suddenly can worsen your condition and cause withdrawal symptoms that may last for several weeks to more than 12 months. Your doctor probably will decrease your chlordiazepoxide dose gradually. Call your doctor or get emergency medical treatment if you experience any of the following symptoms: unusual movements; ringing in your ears; anxiety; memory problems; difficulty concentrating; sleep problems; seizures; shaking; muscle twitching; changes in mental health; depression; burning or prickling feeling in hands, arms, legs or feet; seeing or hearing things that others do not see or hear; thoughts of harming or killing yourself or others; overexcitement; or losing touch with reality.

Chlordiazepoxide is used to relieve anxiety and to control agitation caused by alcohol withdrawal. Chlordiazepoxide is in a class of medications called benzodiazepines. It works by decreasing abnormal electrical activity in the brain.

Chlordiazepoxide comes as a tablet and capsule to take by mouth. It usually is taken one to four times a day with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take chlordiazepoxide exactly as directed.

Chlordiazepoxide is also used to treat irritable bowel syndrome. Talk to your doctor about the possible risks of using this medication for your condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking chlordiazepoxide,

  • tell your doctor and pharmacist if you are allergic to chlordiazepoxide, alprazolam (Xanax), clonazepam (Klonopin), clorazepate (Gen-Xene, Tranxene), diazepam (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam, temazepam (Restoril), triazolam (Halcion), any other medications, or any of the ingredients in tablets and capsules. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antihistamines; cimetidine (Tagamet); digoxin (Lanoxin); disulfiram (Antabuse); fluoxetine (Prozac, Sarafem, Selfemra); isoniazid (Laniazid, in Rifamate, in Rifater); ketoconazole (Nizoral); levodopa (in Ritary, in Sinemet, in Stalevo); medications for depression, seizures, Parkinson's disease, asthma, colds, or allergies; metoprolol (Lopressor, Toprol XL, others); muscle relaxants; oral contraceptives; probenecid (Probalan, in Col-Probenecid); propranolol (Inderal, Innopran); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); sedatives; sleeping pills; theophylline (Elixophyllin, Theo 24, Theochron); tranquilizers; and valproic acid (Depakene). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had glaucoma; seizures; or lung, heart, or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking chlordiazepoxide, call your doctor immediately.

  • talk to your doctor about the risks and benefits of taking chlordiazepoxide if you are 65 years of age or older. Older adults should not usually take chlordiazepoxide because it is not as safe or effective as other medication(s) that can be used to treat the same condition.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking chlordiazepoxide.

  • you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

If you take several doses per day and miss a dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Chlordiazepoxide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • drowsiness

    • dizziness

    • tiredness

    • weakness

    • dry mouth

    • diarrhea

    • upset stomach

    • changes in appetite

  • Tell your doctor if any of these symptoms are severe or do not go away:

    • restlessness or excitement

    • constipation

    • difficulty urinating

    • frequent urination

    • blurred vision

    • changes in sex drive or ability

  • Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical help:

    • shuffling walk

    • persistent, fine tremor or inability to sit still

    • fever

    • difficulty breathing or swallowing

    • severe skin rash

    • yellowing of the skin or eyes

    • irregular heartbeat

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

Chlordiazepoxide can cause false results when using the Gravindex pregnancy test.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Limbitrol® (containing Amitriptyline, Chlordiazepoxide)
  • Menrium® (containing Chlordiazepoxide, Esterified Estrogens)

Drug Interaction
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Dolasetron.
Aminophylline Aminophylline The therapeutic efficacy of Chlordiazepoxide can be decreased when used in combination with Aminophylline.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Chlordiazepoxide.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Guanfacine.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Naratriptan.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Chlordiazepoxide.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Chlordiazepoxide.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Chlordiazepoxide.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Sumatriptan.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Tizanidine.
Zolmitriptan Zolmitriptan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Chlordiazepoxide.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Chlordiazepoxide.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Meperidine is combined with Chlordiazepoxide.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Chlordiazepoxide.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Chlordiazepoxide.
Altretamine Altretamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Chlordiazepoxide.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Ondansetron.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Granisetron.
Olanzapine Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Chlordiazepoxide.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Alosetron.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Entacapone.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Oxcarbazepine.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Zaleplon.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Desloratadine.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Linezolid.
Trimipramine Trimipramine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Trimipramine.
Glycopyrrolate Glycopyrrolate Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Escitalopram Escitalopram The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Escitalopram.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Zonisamide.
Aripiprazole Aripiprazole The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Chlordiazepoxide.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Dexmethylphenidate.
Almotriptan Almotriptan The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Almotriptan.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Chlordiazepoxide.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Frovatriptan.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Apomorphine.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Protriptyline is combined with Chlordiazepoxide.
Duloxetine Duloxetine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Duloxetine.
Trospium Trospium Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Chlordiazepoxide is combined with Eszopiclone.
Solifenacin Solifenacin Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dextroamphetamine Dextroamphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Chlordiazepoxide.
Sodium Oxybate Sodium Oxybate Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Isocarboxazid Isocarboxazid The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Isocarboxazid.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Ramelteon.
Darifenacin Darifenacin Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Chlordiazepoxide.
Pregabalin Pregabalin The therapeutic efficacy of Chlordiazepoxide can be increased when used in combination with Pregabalin.
Phenylephrine Phenylephrine The risk or severity of hypertension can be decreased when Chlordiazepoxide is combined with Phenylephrine.
Felbamate Felbamate The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Felbamate.
Rasagiline Rasagiline The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Rasagiline.
Paliperidone Paliperidone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Paliperidone.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Dimenhydrinate.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Levocetirizine.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Chlordiazepoxide.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Chlordiazepoxide.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Desvenlafaxine.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Chlordiazepoxide.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Midazolam.
Naltrexone Injection Naltrexone Injection The risk or severity of adverse effects can be increased when Naltrexone is combined with Chlordiazepoxide.
Milnacipran Milnacipran The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Milnacipran.
Fesoterodine Fesoterodine Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Iloperidone Iloperidone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Iloperidone.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Lacosamide.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Chlordiazepoxide.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Chlordiazepoxide.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Asenapine Asenapine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Vigabatrin.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Oxymorphone is combined with Chlordiazepoxide.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Chlordiazepoxide.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Lurasidone.
Vilazodone Vilazodone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Vilazodone.
Clobazam Clobazam The risk or severity of adverse effects can be increased when Clobazam is combined with Chlordiazepoxide.
Cabergoline Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Chlordiazepoxide.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Tiagabine.
Teduglutide Injection Teduglutide Injection The serum concentration of Chlordiazepoxide can be increased when it is combined with Teduglutide.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Pomalidomide.
Levomilnacipran Levomilnacipran The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Levomilnacipran.
Vortioxetine Vortioxetine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Eslicarbazepine.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Suvorexant Suvorexant Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Methamphetamine Methamphetamine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Metamfetamine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Tasimelteon.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Risperidone.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Chlordiazepoxide is combined with Haloperidol.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Flibanserin.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Chlordiazepoxide.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Cariprazine.
Eluxadoline Eluxadoline The risk or severity of adverse effects can be increased when Eluxadoline is combined with Chlordiazepoxide.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Brivaracetam.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Diphenhydramine.
Doxepin (Insomnia) Doxepin (Insomnia) The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Doxepin.
Deutetrabenazine Deutetrabenazine The risk or severity of sedation and somnolence can be increased when Chlordiazepoxide is combined with Deutetrabenazine.
Safinamide Safinamide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Safinamide.
Tetrabenazine Tetrabenazine The risk or severity of sedation and somnolence can be increased when Chlordiazepoxide is combined with Tetrabenazine.
Buprenorphine Injection Buprenorphine Injection Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lofexidine Lofexidine The therapeutic efficacy of Chlordiazepoxide can be increased when used in combination with Lofexidine.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Chlordiazepoxide.
Stiripentol Stiripentol The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Stiripentol.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Solriamfetol.
Phenytoin Injection Phenytoin Injection The serum concentration of Chlordiazepoxide can be increased when it is combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Fosphenytoin can be increased when it is combined with Chlordiazepoxide.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Lasmiditan.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Fenfluramine.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Viloxazine.
Theophylline Theophylline The therapeutic efficacy of Chlordiazepoxide can be decreased when used in combination with Theophylline.
Trazodone Trazodone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Trazodone.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Phenobarbital.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Metaxalone.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Chlordiazepoxide.
Primidone Primidone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Primidone.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Diethylpropion.
Chlorpromazine Chlorpromazine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Chlorpromazine.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Diazepam.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Oxazepam.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Flurazepam.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Clorazepic acid.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Chlordiazepoxide.
Codeine Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Chlordiazepoxide.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Chlordiazepoxide.
Bromocriptine Bromocriptine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Bromocriptine.
Tranylcypromine Tranylcypromine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Tranylcypromine.
Phenelzine Phenelzine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Ergoloid mesylate.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Chlordiazepoxide.
Thioridazine Thioridazine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Thioridazine.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Trifluoperazine.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Chlordiazepoxide.
Methadone Methadone Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Methadone.
Oxybutynin Oxybutynin Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine Benztropine Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline Maprotiline The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Maprotiline.
Trihexyphenidyl Trihexyphenidyl Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Perphenazine.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Fluphenazine.
Amoxapine Amoxapine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Amoxapine.
Carbamazepine Carbamazepine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Carbamazepine.
Molindone Molindone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Molindone.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Chlordiazepoxide.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Clonazepam.
Promethazine Promethazine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Promethazine.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Chlordiazepoxide.
Quinine Quinine The risk or severity of adverse effects can be increased when Quinine is combined with Chlordiazepoxide.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Ethosuximide.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Chlordiazepoxide.
Desipramine Desipramine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Desipramine.
Imipramine Imipramine The risk or severity of adverse effects can be increased when Imipramine is combined with Chlordiazepoxide.
Quinidine Quinidine Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Quinidine.
Disopyramide Disopyramide Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Disopyramide.
Valproic Acid Valproic Acid The risk or severity of adverse effects can be increased when Valproic acid is combined with Chlordiazepoxide.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Chlordiazepoxide.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Chlordiazepoxide is combined with Cyclobenzaprine.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Chlordiazepoxide.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Cyproheptadine Cyproheptadine Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Chlordiazepoxide.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Chlordiazepoxide.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Meclizine.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Chlordiazepoxide.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Chlordiazepoxide.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Chlordiazepoxide.
Nortriptyline Nortriptyline The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Nortriptyline.
Mercaptopurine Mercaptopurine The therapeutic efficacy of Chlordiazepoxide can be decreased when used in combination with Mercaptopurine.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Chlordiazepoxide.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Chlordiazepoxide.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Trimethobenzamide.
Flavoxate Flavoxate Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Acetazolamide.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Pyrantel.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Thiothixene.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Chlordiazepoxide.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Chlordiazepoxide.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Triazolam.
Dicyclomine Dicyclomine Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Pindolol.
Pentoxifylline Pentoxifylline The therapeutic efficacy of Chlordiazepoxide can be decreased when used in combination with Pentoxifylline.
Pimozide Pimozide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Pimozide.
Fluoxetine Fluoxetine The serum concentration of Chlordiazepoxide can be increased when it is combined with Fluoxetine.
Clozapine Clozapine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Estazolam.
Zolpidem Zolpidem Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Cisapride Cisapride The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Cisapride.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Gabapentin.
Venlafaxine Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Chlordiazepoxide.
Fluvoxamine Fluvoxamine The risk or severity of adverse effects can be increased when Fluvoxamine is combined with Chlordiazepoxide.
Nefazodone Nefazodone The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Nefazodone.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Lamotrigine.
Tramadol Tramadol The risk or severity of CNS depression can be increased when Tramadol is combined with Chlordiazepoxide.
Nicardipine Nicardipine Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Nicardipine.
Bupropion Bupropion The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Bupropion.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Riluzole.
Clomipramine Clomipramine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Clomipramine.
Mirtazapine Mirtazapine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Chlordiazepoxide.
Pramipexole Pramipexole Chlordiazepoxide may increase the sedative activities of Pramipexole.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Donepezil.
Selegiline Selegiline The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Selegiline.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Sertraline.
Ropinirole Ropinirole Chlordiazepoxide may increase the sedative activities of Ropinirole.
Quetiapine Quetiapine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Quetiapine.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Chlordiazepoxide.
Paroxetine Paroxetine The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Paroxetine.
Tolcapone Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Chlordiazepoxide.
Citalopram Citalopram The risk or severity of adverse effects can be increased when Citalopram is combined with Chlordiazepoxide.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Efavirenz.
Tolterodine Tolterodine Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Levetiracetam.

* This branded product is no longer on the market. Generic alternatives may be available.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists